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Recurrent Bladder Squamous Cell Carcinoma

MedGen UID:
208968
•Concept ID:
C0855186
•
Neoplastic Process
Synonyms: Recurrent Bladder Epidermoid Carcinoma; Recurrent Epidermoid Carcinoma of Bladder; Recurrent Epidermoid Carcinoma of the Bladder; Recurrent Epidermoid Carcinoma of the Urinary Bladder; Recurrent Epidermoid Carcinoma of Urinary Bladder; Recurrent Squamous Cell Carcinoma of Bladder; Recurrent Squamous Cell Carcinoma of the Bladder; Recurrent Squamous Cell Carcinoma of the Urinary Bladder; Recurrent Squamous Cell Carcinoma of Urinary Bladder; Recurrent Urinary Bladder Epidermoid Carcinoma; Recurrent Urinary Bladder Squamous Cell Carcinoma; Relapsed Bladder Epidermoid Carcinoma; Relapsed Bladder Squamous Cell Carcinoma; Relapsed Epidermoid Carcinoma of Bladder; Relapsed Epidermoid Carcinoma of the Bladder; Relapsed Epidermoid Carcinoma of the Urinary Bladder; Relapsed Epidermoid Carcinoma of Urinary Bladder; Relapsed Squamous Cell Carcinoma of Bladder; Relapsed Squamous Cell Carcinoma of the Bladder; Relapsed Squamous Cell Carcinoma of the Urinary Bladder; Relapsed Squamous Cell Carcinoma of Urinary Bladder; Relapsed Urinary Bladder Epidermoid Carcinoma; Relapsed Urinary Bladder Squamous Cell Carcinoma; Squamous Cell Carcinoma of Bladder, Recurrent; Squamous Cell Carcinoma of the Bladder, Recurrent

Definition

The reemergence of bladder squamous cell carcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Bladder Squamous Cell Carcinoma

Professional guidelines

PubMed

Current Disease Management of Primary Urethral Carcinoma.
Janisch F, Abufaraj M, Fajkovic H, Kimura S, Iwata T, Nyirady P, Rink M, Shariat SF
Eur Urol Focus 2019 Sep;5(5):722-734. Epub 2019 Jul 13 doi: 10.1016/j.euf.2019.07.001. PMID: 31307949
Patient Characteristics, Treatment Patterns and Prognostic Factors in Squamous Cell Bladder Cancer.
Zahoor H, Elson P, Stephenson A, Haber GP, Kaouk J, Fergany A, Lee B, Koshkin V, Ornstein M, Gilligan T, Garcia JA, Rini B, Grivas P
Clin Genitourin Cancer 2018 Apr;16(2):e437-e442. Epub 2017 Oct 17 doi: 10.1016/j.clgc.2017.10.005. PMID: 29154041
The biology and treatment of superficial bladder cancer.
Torti FM, Lum BL
J Clin Oncol 1984 May;2(5):505-31. doi: 10.1200/JCO.1984.2.5.505. PMID: 6427417

Recent clinical studies

Etiology

Clinicopathologic and Survival After Cystectomy Outcomes in Squamous Cell Carcinoma of the Bladder.
Agrawal P, Rostom M, Alam R, Florissi I, Biles M, Rodriguez K, Hahn NM, Johnson BA 3rd, Matoso A, Smith A, Bivalacqua TJ, Kates M, Hoffman-Censits J, Patel SH
Clin Genitourin Cancer 2023 Dec;21(6):631-638.e1. Epub 2023 May 30 doi: 10.1016/j.clgc.2023.05.019. PMID: 37336703
Neoadjuvant Pembrolizumab and Radical Cystectomy in Patients with Muscle-Invasive Urothelial Bladder Cancer: 3-Year Median Follow-Up Update of PURE-01 Trial.
Basile G, Bandini M, Gibb EA, Ross JS, Raggi D, Marandino L, Costa de Padua T, Crupi E, Colombo R, Colecchia M, Lucianò R, Nocera L, Moschini M, Briganti A, Montorsi F, Necchi A
Clin Cancer Res 2022 Dec 1;28(23):5107-5114. doi: 10.1158/1078-0432.CCR-22-2158. PMID: 36190522
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma.
Powles T, Assaf ZJ, Davarpanah N, Banchereau R, Szabados BE, Yuen KC, Grivas P, Hussain M, Oudard S, Gschwend JE, Albers P, Castellano D, Nishiyama H, Daneshmand S, Sharma S, Zimmermann BG, Sethi H, Aleshin A, Perdicchio M, Zhang J, Shames DS, Degaonkar V, Shen X, Carter C, Bais C, Bellmunt J, Mariathasan S
Nature 2021 Jul;595(7867):432-437. Epub 2021 Jun 16 doi: 10.1038/s41586-021-03642-9. PMID: 34135506
Hormone Replacement Therapy in Cancer Survivors - Review of the Literature.
Deli T, Orosz M, Jakab A
Pathol Oncol Res 2020 Jan;26(1):63-78. Epub 2019 Jan 8 doi: 10.1007/s12253-018-00569-x. PMID: 30617760Free PMC Article
Condyloma Acuminatum of Urinary Bladder: Relation to Squamous Cell Carcinoma.
Samarska IV, Epstein JI
Am J Surg Pathol 2019 Nov;43(11):1547-1553. doi: 10.1097/PAS.0000000000001339. PMID: 31368913

Diagnosis

ctDNA guiding adjuvant immunotherapy in urothelial carcinoma.
Powles T, Assaf ZJ, Davarpanah N, Banchereau R, Szabados BE, Yuen KC, Grivas P, Hussain M, Oudard S, Gschwend JE, Albers P, Castellano D, Nishiyama H, Daneshmand S, Sharma S, Zimmermann BG, Sethi H, Aleshin A, Perdicchio M, Zhang J, Shames DS, Degaonkar V, Shen X, Carter C, Bais C, Bellmunt J, Mariathasan S
Nature 2021 Jul;595(7867):432-437. Epub 2021 Jun 16 doi: 10.1038/s41586-021-03642-9. PMID: 34135506
Condyloma Acuminatum of Urinary Bladder: Relation to Squamous Cell Carcinoma.
Samarska IV, Epstein JI
Am J Surg Pathol 2019 Nov;43(11):1547-1553. doi: 10.1097/PAS.0000000000001339. PMID: 31368913
Patient Characteristics, Treatment Patterns and Prognostic Factors in Squamous Cell Bladder Cancer.
Zahoor H, Elson P, Stephenson A, Haber GP, Kaouk J, Fergany A, Lee B, Koshkin V, Ornstein M, Gilligan T, Garcia JA, Rini B, Grivas P
Clin Genitourin Cancer 2018 Apr;16(2):e437-e442. Epub 2017 Oct 17 doi: 10.1016/j.clgc.2017.10.005. PMID: 29154041
miRNA and cancer; computational and experimental approaches.
Tutar Y
Curr Pharm Biotechnol 2014;15(5):429. doi: 10.2174/138920101505140828161335. PMID: 25189575
Bladder cancer in Africa.
Heyns CF, van der Merwe A
Can J Urol 2008 Feb;15(1):3899-908. PMID: 18304401

Therapy

Neoadjuvant Pembrolizumab and Radical Cystectomy in Patients with Muscle-Invasive Urothelial Bladder Cancer: 3-Year Median Follow-Up Update of PURE-01 Trial.
Basile G, Bandini M, Gibb EA, Ross JS, Raggi D, Marandino L, Costa de Padua T, Crupi E, Colombo R, Colecchia M, Lucianò R, Nocera L, Moschini M, Briganti A, Montorsi F, Necchi A
Clin Cancer Res 2022 Dec 1;28(23):5107-5114. doi: 10.1158/1078-0432.CCR-22-2158. PMID: 36190522
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma.
Powles T, Assaf ZJ, Davarpanah N, Banchereau R, Szabados BE, Yuen KC, Grivas P, Hussain M, Oudard S, Gschwend JE, Albers P, Castellano D, Nishiyama H, Daneshmand S, Sharma S, Zimmermann BG, Sethi H, Aleshin A, Perdicchio M, Zhang J, Shames DS, Degaonkar V, Shen X, Carter C, Bais C, Bellmunt J, Mariathasan S
Nature 2021 Jul;595(7867):432-437. Epub 2021 Jun 16 doi: 10.1038/s41586-021-03642-9. PMID: 34135506
Adjuvant and Neoadjuvant Radiation Therapy for Locally Advanced Bladder Cancer.
Baumann BC, Zaghloul MS, Sargos P, Murthy V
Clin Oncol (R Coll Radiol) 2021 Jun;33(6):391-399. doi: 10.1016/j.clon.2021.03.020. PMID: 33972025
Hormone Replacement Therapy in Cancer Survivors - Review of the Literature.
Deli T, Orosz M, Jakab A
Pathol Oncol Res 2020 Jan;26(1):63-78. Epub 2019 Jan 8 doi: 10.1007/s12253-018-00569-x. PMID: 30617760Free PMC Article
Patient Characteristics, Treatment Patterns and Prognostic Factors in Squamous Cell Bladder Cancer.
Zahoor H, Elson P, Stephenson A, Haber GP, Kaouk J, Fergany A, Lee B, Koshkin V, Ornstein M, Gilligan T, Garcia JA, Rini B, Grivas P
Clin Genitourin Cancer 2018 Apr;16(2):e437-e442. Epub 2017 Oct 17 doi: 10.1016/j.clgc.2017.10.005. PMID: 29154041

Prognosis

Neoadjuvant Pembrolizumab and Radical Cystectomy in Patients with Muscle-Invasive Urothelial Bladder Cancer: 3-Year Median Follow-Up Update of PURE-01 Trial.
Basile G, Bandini M, Gibb EA, Ross JS, Raggi D, Marandino L, Costa de Padua T, Crupi E, Colombo R, Colecchia M, Lucianò R, Nocera L, Moschini M, Briganti A, Montorsi F, Necchi A
Clin Cancer Res 2022 Dec 1;28(23):5107-5114. doi: 10.1158/1078-0432.CCR-22-2158. PMID: 36190522
Squamous or Glandular Differentiation Predicts Poor Prognosis in pT1 Urothelial Carcinoma.
Nakagawa R, Iwamoto H, Makino T, Kadomoto S, Yaegashi H, Shigehara K, Izumi K, Kadono Y, Mizokami A
In Vivo 2022 Sep-Oct;36(5):2365-2370. doi: 10.21873/invivo.12968. PMID: 36099139Free PMC Article
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma.
Powles T, Assaf ZJ, Davarpanah N, Banchereau R, Szabados BE, Yuen KC, Grivas P, Hussain M, Oudard S, Gschwend JE, Albers P, Castellano D, Nishiyama H, Daneshmand S, Sharma S, Zimmermann BG, Sethi H, Aleshin A, Perdicchio M, Zhang J, Shames DS, Degaonkar V, Shen X, Carter C, Bais C, Bellmunt J, Mariathasan S
Nature 2021 Jul;595(7867):432-437. Epub 2021 Jun 16 doi: 10.1038/s41586-021-03642-9. PMID: 34135506
Condyloma Acuminatum of Urinary Bladder: Relation to Squamous Cell Carcinoma.
Samarska IV, Epstein JI
Am J Surg Pathol 2019 Nov;43(11):1547-1553. doi: 10.1097/PAS.0000000000001339. PMID: 31368913
miRNA and cancer; computational and experimental approaches.
Tutar Y
Curr Pharm Biotechnol 2014;15(5):429. doi: 10.2174/138920101505140828161335. PMID: 25189575

Clinical prediction guides

Neoadjuvant Pembrolizumab and Radical Cystectomy in Patients with Muscle-Invasive Urothelial Bladder Cancer: 3-Year Median Follow-Up Update of PURE-01 Trial.
Basile G, Bandini M, Gibb EA, Ross JS, Raggi D, Marandino L, Costa de Padua T, Crupi E, Colombo R, Colecchia M, Lucianò R, Nocera L, Moschini M, Briganti A, Montorsi F, Necchi A
Clin Cancer Res 2022 Dec 1;28(23):5107-5114. doi: 10.1158/1078-0432.CCR-22-2158. PMID: 36190522
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma.
Powles T, Assaf ZJ, Davarpanah N, Banchereau R, Szabados BE, Yuen KC, Grivas P, Hussain M, Oudard S, Gschwend JE, Albers P, Castellano D, Nishiyama H, Daneshmand S, Sharma S, Zimmermann BG, Sethi H, Aleshin A, Perdicchio M, Zhang J, Shames DS, Degaonkar V, Shen X, Carter C, Bais C, Bellmunt J, Mariathasan S
Nature 2021 Jul;595(7867):432-437. Epub 2021 Jun 16 doi: 10.1038/s41586-021-03642-9. PMID: 34135506
Expression and prognostic utility of PD-L1 in patients with squamous cell carcinoma of the bladder.
Owyong M, Lotan Y, Kapur P, Panwar V, McKenzie T, Lee TK, Zi X, Martin JW, Mosbah A, Abol-Enein H, Ghoneim M, Youssef RF
Urol Oncol 2019 Jul;37(7):478-484. Epub 2019 Mar 23 doi: 10.1016/j.urolonc.2019.02.017. PMID: 30910351
Clinical Significance of Squamous Differentiation in Urothelial Carcinoma of the Bladder.
Minato A, Noguchi H, Tomisaki I, Fukuda A, Kubo T, Nakayama T, Fujimoto N
Cancer Control 2018 Jan-Dec;25(1):1073274818800269. doi: 10.1177/1073274818800269. PMID: 30213195Free PMC Article
miRNA and cancer; computational and experimental approaches.
Tutar Y
Curr Pharm Biotechnol 2014;15(5):429. doi: 10.2174/138920101505140828161335. PMID: 25189575

Recent systematic reviews

The clinicopathological characteristics and prognostic value of squamous differentiation in patients with bladder urothelial carcinoma: a meta-analysis.
Lin X, Deng T, Wu S, Lin SX, Wang D, Wu CL
World J Urol 2020 Feb;38(2):323-333. Epub 2019 Apr 22 doi: 10.1007/s00345-019-02771-1. PMID: 31011874
Current Disease Management of Primary Urethral Carcinoma.
Janisch F, Abufaraj M, Fajkovic H, Kimura S, Iwata T, Nyirady P, Rink M, Shariat SF
Eur Urol Focus 2019 Sep;5(5):722-734. Epub 2019 Jul 13 doi: 10.1016/j.euf.2019.07.001. PMID: 31307949
Chronic urinary tract infection and bladder carcinoma risk: a meta-analysis of case-control and cohort studies.
Akhtar S, Al-Shammari A, Al-Abkal J
World J Urol 2018 Jun;36(6):839-848. Epub 2018 Feb 5 doi: 10.1007/s00345-018-2206-x. PMID: 29404674

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