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Toxocariasis

MedGen UID:
21596
Concept ID:
C0040553
Disease or Syndrome
Synonym: Toxocariases
SNOMED CT: Toxocara infection (406619001); Toxocariasis (406619001); Infection due to Toxocara (406619001); Infection caused by Toxocara (406619001)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0005988
Orphanet: ORPHA3343

Definition

A cosmopolitan zoonotic disease caused in humans by the accidental ingestion of eggs or larvae of the ascarids <i>Toxocara canis</i> or <i>Toxocara cati</i>, the common round worm of dogs and cats respectively. The infestation can be asymptomatic or can present as visceral larva migrans caused by larval migration through major organs such as liver, lungs or central nervous system (manifesting with fever, cough, hepatomegaly, pneumonia or rarely encephalitis), or as ocular larva migrans caused by larval migration to the eye (manifesting as ocular inflammation and retinal scaring). [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVToxocariasis
Follow this link to review classifications for Toxocariasis in Orphanet.

Professional guidelines

PubMed

Yoon SY, Baek S, Park SY, Shin B, Kwon HS, Cho YS, Moon HB, Kim TB
Medicine (Baltimore) 2018 Sep;97(37):e12361. doi: 10.1097/MD.0000000000012361. PMID: 30212995Free PMC Article
Schneier AJ, Durand ML
Int Ophthalmol Clin 2011 Fall;51(4):135-44. doi: 10.1097/IIO.0b013e31822d6a5a. PMID: 21897146
Pawlowski Z
J Helminthol 2001 Dec;75(4):299-305. doi: 10.1017/s0022149x01000464. PMID: 11818044

Recent clinical studies

Etiology

Healy SR, Morgan ER, Prada JM, Betson M
Parasitology 2022 Jan;149(1):1-9. Epub 2021 Oct 25 doi: 10.1017/S0031182021001591. PMID: 34694217Free PMC Article
Magnaval JF, Fillaux J, Cassaing S, Valentin A, Iriart X, Berry A
Parasite 2020;27:32. Epub 2020 May 13 doi: 10.1051/parasite/2020029. PMID: 32400389Free PMC Article
Taylan-Ozkan A
Adv Parasitol 2020;109:465-482. Epub 2020 Feb 10 doi: 10.1016/bs.apar.2020.01.021. PMID: 32381213
Fialho PMM, Correa CRS, Lescano SZ
Adv Parasitol 2020;109:357-374. Epub 2020 Jan 31 doi: 10.1016/bs.apar.2020.01.013. PMID: 32381207
Ponce-Macotela M, Martínez-Gordillo MN
Adv Parasitol 2020;109:341-355. Epub 2020 Feb 5 doi: 10.1016/bs.apar.2020.01.012. PMID: 32381206

Diagnosis

Fialho PMM, Correa CRS, Lescano SZ
Adv Parasitol 2020;109:357-374. Epub 2020 Jan 31 doi: 10.1016/bs.apar.2020.01.013. PMID: 32381207
Nicoletti A
Adv Parasitol 2020;109:219-231. Epub 2020 Jan 31 doi: 10.1016/bs.apar.2020.01.007. PMID: 32381199
Dietrich CF, Cretu C, Dong Y
Adv Parasitol 2020;109:165-187. Epub 2020 Apr 25 doi: 10.1016/bs.apar.2020.03.001. PMID: 32381196
Chen J, Liu Q, Liu GH, Zheng WB, Hong SJ, Sugiyama H, Zhu XQ, Elsheikha HM
Infect Dis Poverty 2018 Jun 13;7(1):59. doi: 10.1186/s40249-018-0437-0. PMID: 29895324Free PMC Article
Ma G, Holland CV, Wang T, Hofmann A, Fan CK, Maizels RM, Hotez PJ, Gasser RB
Lancet Infect Dis 2018 Jan;18(1):e14-e24. Epub 2017 Aug 3 doi: 10.1016/S1473-3099(17)30331-6. PMID: 28781085

Therapy

Rostami A, Ma G, Wang T, Koehler AV, Hofmann A, Chang BCH, Macpherson CN, Gasser RB
Infect Genet Evol 2019 Oct;74:104002. Epub 2019 Aug 11 doi: 10.1016/j.meegid.2019.104002. PMID: 31412276
Deshayes S, Bonhomme J, de La Blanchardière A
Infection 2016 Oct;44(5):565-74. Epub 2016 Mar 23 doi: 10.1007/s15010-016-0889-8. PMID: 27084369
Li L, Gao W, Yang X, Wu D, Bi H, Zhang S, Huang M, Yao X
Ann Allergy Asthma Immunol 2014 Aug;113(2):187-92. Epub 2014 Jun 13 doi: 10.1016/j.anai.2014.05.016. PMID: 24934109
Quattrocchi G, Nicoletti A, Marin B, Bruno E, Druet-Cabanac M, Preux PM
PLoS Negl Trop Dis 2012;6(8):e1775. Epub 2012 Aug 14 doi: 10.1371/journal.pntd.0001775. PMID: 22905274Free PMC Article
Pawlowski Z
J Helminthol 2001 Dec;75(4):299-305. doi: 10.1017/s0022149x01000464. PMID: 11818044

Prognosis

Akhmadishina LV, Ruzina MN, Lukasheva MA, Kyuregyan KK, Mikhailov MI, Lukashev AN
Adv Parasitol 2020;109:419-432. Epub 2020 Apr 9 doi: 10.1016/bs.apar.2020.01.015. PMID: 32381210
Padhi TR, Das S, Sharma S, Rath S, Rath S, Tripathy D, Panda KG, Basu S, Besirli CG
Surv Ophthalmol 2017 Mar-Apr;62(2):161-189. Epub 2016 Oct 6 doi: 10.1016/j.survophthal.2016.09.005. PMID: 27720858
Martínez-Pulgarín DF, Muñoz-Urbano M, Gomez-Suta LD, Delgado OM, Rodriguez-Morales AJ
Recent Pat Antiinfect Drug Discov 2015;10(1):35-41. doi: 10.2174/1574891x10666150410125057. PMID: 25858303
Finsterer J, Auer H
Rev Inst Med Trop Sao Paulo 2007 Sep-Oct;49(5):279-87. doi: 10.1590/s0036-46652007000500002. PMID: 18026633
Pawlowski Z
J Helminthol 2001 Dec;75(4):299-305. doi: 10.1017/s0022149x01000464. PMID: 11818044

Clinical prediction guides

Fan CK
Adv Parasitol 2020;109:233-259. Epub 2020 Feb 5 doi: 10.1016/bs.apar.2020.01.008. PMID: 32381200
Deshayes S, Bonhomme J, de La Blanchardière A
Infection 2016 Oct;44(5):565-74. Epub 2016 Mar 23 doi: 10.1007/s15010-016-0889-8. PMID: 27084369
Martínez-Pulgarín DF, Muñoz-Urbano M, Gomez-Suta LD, Delgado OM, Rodriguez-Morales AJ
Recent Pat Antiinfect Drug Discov 2015;10(1):35-41. doi: 10.2174/1574891x10666150410125057. PMID: 25858303
Pawlowski Z
J Helminthol 2001 Dec;75(4):299-305. doi: 10.1017/s0022149x01000464. PMID: 11818044
Goscienski PJ
Pediatr Infect Dis 1983 Jan-Feb;2(1):69-81. doi: 10.1097/00006454-198301000-00018. PMID: 6340080

Recent systematic reviews

Luna J, Cicero CE, Rateau G, Quattrocchi G, Marin B, Bruno E, Dalmay F, Druet-Cabanac M, Nicoletti A, Preux PM
PLoS Negl Trop Dis 2018 Jul;12(7):e0006665. Epub 2018 Jul 20 doi: 10.1371/journal.pntd.0006665. PMID: 30028858Free PMC Article
Deshayes S, Bonhomme J, de La Blanchardière A
Infection 2016 Oct;44(5):565-74. Epub 2016 Mar 23 doi: 10.1007/s15010-016-0889-8. PMID: 27084369
Fialho PM, Corrêa CR
Am J Trop Med Hyg 2016 Jun 1;94(6):1193-9. Epub 2016 Feb 1 doi: 10.4269/ajtmh.15-0733. PMID: 26834201Free PMC Article
Li L, Gao W, Yang X, Wu D, Bi H, Zhang S, Huang M, Yao X
Ann Allergy Asthma Immunol 2014 Aug;113(2):187-92. Epub 2014 Jun 13 doi: 10.1016/j.anai.2014.05.016. PMID: 24934109
Quattrocchi G, Nicoletti A, Marin B, Bruno E, Druet-Cabanac M, Preux PM
PLoS Negl Trop Dis 2012;6(8):e1775. Epub 2012 Aug 14 doi: 10.1371/journal.pntd.0001775. PMID: 22905274Free PMC Article

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