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Helminthiasis

MedGen UID:
6765
•Concept ID:
C0018889
•
Disease or Syndrome
Synonym: Worm infections
SNOMED CT: Helminth infection (27601005); Helminthiasis (27601005); Helminthosis (27601005); Worms (27601005); Worm infestation (27601005); Worm infection (27601005); Infection caused by Cestoda and/or Trematoda and/or Phylum Nemata (27601005)
 
Monarch Initiative: MONDO:0004664

Definition

A parasitic infection characterized by the infestation with worms, mainly in the intestine. [from NCI]

Professional guidelines

PubMed

Praziquantel and risk of visual disorders: Case series assessment.
Debesai M, Russom M
PLoS Negl Trop Dis 2020 Apr;14(4):e0008198. Epub 2020 Apr 15 doi: 10.1371/journal.pntd.0008198. PMID: 32294081Free PMC Article
Worm Infestation: Diagnosis, Treatment and Prevention.
Bharti B, Bharti S, Khurana S
Indian J Pediatr 2018 Nov;85(11):1017-1024. Epub 2017 Nov 11 doi: 10.1007/s12098-017-2505-z. PMID: 29127616
Management of imported cutaneous larva migrans: A case series and mini-review.
Kincaid L, Klowak M, Klowak S, Boggild AK
Travel Med Infect Dis 2015 Sep-Oct;13(5):382-7. Epub 2015 Jul 29 doi: 10.1016/j.tmaid.2015.07.007. PMID: 26243366

Recent clinical studies

Etiology

Anaemia in pregnancy.
Frayne J, Pinchon D
Aust J Gen Pract 2019 Mar;48(3):125-129. doi: 10.31128/AJGP-08-18-4664. PMID: 31256475
Host responses to intestinal nematodes.
Yasuda K, Nakanishi K
Int Immunol 2018 Mar 10;30(3):93-102. doi: 10.1093/intimm/dxy002. PMID: 29346656
Soil-transmitted helminth infections.
Jourdan PM, Lamberton PHL, Fenwick A, Addiss DG
Lancet 2018 Jan 20;391(10117):252-265. Epub 2017 Sep 4 doi: 10.1016/S0140-6736(17)31930-X. PMID: 28882382
Helminths in organ transplantation.
Cooper AJR, Dholakia S, Holland CV, Friend PJ
Lancet Infect Dis 2017 Jun;17(6):e166-e176. Epub 2017 Feb 21 doi: 10.1016/S1473-3099(16)30533-3. PMID: 28233632
Neurotoxocarosis.
Finsterer J, Auer H
Rev Inst Med Trop Sao Paulo 2007 Sep-Oct;49(5):279-87. doi: 10.1590/s0036-46652007000500002. PMID: 18026633

Diagnosis

Anaemia in pregnancy.
Frayne J, Pinchon D
Aust J Gen Pract 2019 Mar;48(3):125-129. doi: 10.31128/AJGP-08-18-4664. PMID: 31256475
Beyond O&P Times Three.
Mohapatra S, Singh DP, Alcid D, Pitchumoni CS
Am J Gastroenterol 2018 Jun;113(6):805-818. Epub 2018 Jun 5 doi: 10.1038/s41395-018-0083-y. PMID: 29867172
Soil-transmitted helminth infections.
Jourdan PM, Lamberton PHL, Fenwick A, Addiss DG
Lancet 2018 Jan 20;391(10117):252-265. Epub 2017 Sep 4 doi: 10.1016/S0140-6736(17)31930-X. PMID: 28882382
Helminths in organ transplantation.
Cooper AJR, Dholakia S, Holland CV, Friend PJ
Lancet Infect Dis 2017 Jun;17(6):e166-e176. Epub 2017 Feb 21 doi: 10.1016/S1473-3099(16)30533-3. PMID: 28233632
Oral helminthic infestations.
Hassona Y, Scully C, Delgado-Azanero W, de Almeida OP
J Investig Clin Dent 2015 May;6(2):99-107. Epub 2014 Feb 27 doi: 10.1111/jicd.12077. PMID: 24574305

Therapy

Beyond O&P Times Three.
Mohapatra S, Singh DP, Alcid D, Pitchumoni CS
Am J Gastroenterol 2018 Jun;113(6):805-818. Epub 2018 Jun 5 doi: 10.1038/s41395-018-0083-y. PMID: 29867172
Soil-transmitted helminth infections.
Jourdan PM, Lamberton PHL, Fenwick A, Addiss DG
Lancet 2018 Jan 20;391(10117):252-265. Epub 2017 Sep 4 doi: 10.1016/S0140-6736(17)31930-X. PMID: 28882382
Intestinal microbiota, fecal microbiota transplantation, and inflammatory bowel disease.
Weingarden AR, Vaughn BP
Gut Microbes 2017 May 4;8(3):238-252. Epub 2017 Feb 10 doi: 10.1080/19490976.2017.1290757. PMID: 28609251Free PMC Article
Helminths in organ transplantation.
Cooper AJR, Dholakia S, Holland CV, Friend PJ
Lancet Infect Dis 2017 Jun;17(6):e166-e176. Epub 2017 Feb 21 doi: 10.1016/S1473-3099(16)30533-3. PMID: 28233632
Helminth Therapy for MS.
Tanasescu R, Constantinescu CS
Curr Top Behav Neurosci 2015;26:195-220. doi: 10.1007/7854_2014_361. PMID: 25472634

Prognosis

Cooperation of ILC2s and T(H)2 cells in the expulsion of intestinal helminth parasites.
Zaiss DMW, Pearce EJ, Artis D, McKenzie ANJ, Klose CSN
Nat Rev Immunol 2024 Apr;24(4):294-302. Epub 2023 Oct 5 doi: 10.1038/s41577-023-00942-1. PMID: 37798539
Diet-microbiota crosstalk and immunity to helminth infection.
Myhill LJ, Williams AR
Parasite Immunol 2023 Apr;45(4):e12965. Epub 2023 Jan 11 doi: 10.1111/pim.12965. PMID: 36571323
Ocular parasitoses: A comprehensive review.
Padhi TR, Das S, Sharma S, Rath S, Rath S, Tripathy D, Panda KG, Basu S, Besirli CG
Surv Ophthalmol 2017 Mar-Apr;62(2):161-189. Epub 2016 Oct 6 doi: 10.1016/j.survophthal.2016.09.005. PMID: 27720858
Helminth Therapy for MS.
Tanasescu R, Constantinescu CS
Curr Top Behav Neurosci 2015;26:195-220. doi: 10.1007/7854_2014_361. PMID: 25472634
Neurotoxocarosis.
Finsterer J, Auer H
Rev Inst Med Trop Sao Paulo 2007 Sep-Oct;49(5):279-87. doi: 10.1590/s0036-46652007000500002. PMID: 18026633

Clinical prediction guides

Eosinophilia in Migrant Children: How Should We Proceed?
Bustamante J, García López-Hortelano M, Barcia C, Díaz Almirón M, Subirats M, Montero Vega D, Mellado MJ, Sainz T
Pediatr Infect Dis J 2022 Feb 1;41(2):102-107. doi: 10.1097/INF.0000000000003390. PMID: 34890375
Twenty-year economic impacts of deworming.
Hamory J, Miguel E, Walker M, Kremer M, Baird S
Proc Natl Acad Sci U S A 2021 Apr 6;118(14) doi: 10.1073/pnas.2023185118. PMID: 33790017Free PMC Article
Parasites and allergy: Observations from Africa.
Mpairwe H, Amoah AS
Parasite Immunol 2019 Jun;41(6):e12589. Epub 2018 Oct 21 doi: 10.1111/pim.12589. PMID: 30216486Free PMC Article
Human parasitology worldwide research.
Garrido-Cardenas JA, Mesa-Valle C, Manzano-Agugliaro F
Parasitology 2018 May;145(6):699-712. Epub 2017 Nov 9 doi: 10.1017/S0031182017001718. PMID: 29117879
Helminth Therapy for MS.
Tanasescu R, Constantinescu CS
Curr Top Behav Neurosci 2015;26:195-220. doi: 10.1007/7854_2014_361. PMID: 25472634

Recent systematic reviews

Soil-transmitted helminthic vaccines: Where are we now?
Wong MTJ, Anuar NS, Noordin R, Tye GJ
Acta Trop 2023 Mar;239:106796. Epub 2022 Dec 29 doi: 10.1016/j.actatropica.2022.106796. PMID: 36586174
Prevalence of intestinal parasitism in preschool and school children in Colombia: Systematic review and meta-analysis.
Pazmiño FA, Mora-Salamanca AF, Mahecha BSP, Moreno EJP, Olivera MJ, Ospina AK, López MC
Trop Med Int Health 2022 Sep;27(9):781-794. Epub 2022 Jul 29 doi: 10.1111/tmi.13800. PMID: 35842926
The effect of helminth infection on vaccine responses in humans and animal models: A systematic review and meta-analysis.
Natukunda A, Zirimenya L, Nassuuna J, Nkurunungi G, Cose S, Elliott AM, Webb EL
Parasite Immunol 2022 Sep;44(9):e12939. Epub 2022 Jul 5 doi: 10.1111/pim.12939. PMID: 35712983Free PMC Article
Malaria and Helminthic Co-Infection during Pregnancy in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.
Tadesse Boltena M, El-Khatib Z, Kebede AS, Asamoah BO, Yaw ASC, Kamara K, Constant Assogba P, Tadesse Boltena A, Adane HT, Hailemeskel E, Biru M
Int J Environ Res Public Health 2022 Apr 29;19(9) doi: 10.3390/ijerph19095444. PMID: 35564842Free PMC Article
Water, sanitation, hygiene, and soil-transmitted helminth infection: a systematic review and meta-analysis.
Strunz EC, Addiss DG, Stocks ME, Ogden S, Utzinger J, Freeman MC
PLoS Med 2014 Mar;11(3):e1001620. Epub 2014 Mar 25 doi: 10.1371/journal.pmed.1001620. PMID: 24667810Free PMC Article

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