U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nematoda infectious disease

MedGen UID:
45025
•Concept ID:
C0027583
•
Disease or Syndrome
Synonyms: Infection, Nematode; Infections, Nematode; Nematode Infection; Nematode Infections
SNOMED CT: Nematode infection (84706005); Nematodiasis (84706005); Infection caused by Nematoda (84706005)
 
Monarch Initiative: MONDO:0005871

Definition

Infections caused by nematode larvae which never develop into the adult stage and migrate through various body tissues. They commonly infect the skin, eyes, and viscera in humans. Ancylostoma brasiliensis causes cutaneous larva migrans. Toxocara causes visceral larva migrans. [from MONDO]

Professional guidelines

PubMed

Angiostrongylus cantonensis in travelers: clinical manifestations, diagnosis, and treatment.
Ansdell V, Wattanagoon Y
Curr Opin Infect Dis 2018 Oct;31(5):399-408. doi: 10.1097/QCO.0000000000000481. PMID: 30138142
Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?
Liao C, Cheng X, Liu M, Wang X, Boireau P
Anticancer Agents Med Chem 2018;18(8):1091-1099. doi: 10.2174/1871520617666171121115847. PMID: 29173187Free PMC Article
Screening, prevention, and treatment for hyperinfection syndrome and disseminated infections caused by Strongyloides stercoralis.
Mejia R, Nutman TB
Curr Opin Infect Dis 2012 Aug;25(4):458-63. doi: 10.1097/QCO.0b013e3283551dbd. PMID: 22691685Free PMC Article

Recent clinical studies

Therapy

Trigonelline is an NAD(+) precursor that improves muscle function during ageing and is reduced in human sarcopenia.
Membrez M, Migliavacca E, Christen S, Yaku K, Trieu J, Lee AK, Morandini F, Giner MP, Stiner J, Makarov MV, Garratt ES, Vasiloglou MF, Chanvillard L, Dalbram E, Ehrlich AM, Sanchez-Garcia JL, Canto C, Karagounis LG, Treebak JT, Migaud ME, Heshmat R, Razi F, Karnani N, Ostovar A, Farzadfar F, Tay SKH, Sanders MJ, Lillycrop KA, Godfrey KM, Nakagawa T, Moco S, Koopman R, Lynch GS, Sorrentino V, Feige JN
Nat Metab 2024 Mar;6(3):433-447. Epub 2024 Mar 19 doi: 10.1038/s42255-024-00997-x. PMID: 38504132Free PMC Article
Strongyloidiasis.
Gordon CA, Utzinger J, Muhi S, Becker SL, Keiser J, Khieu V, Gray DJ
Nat Rev Dis Primers 2024 Jan 25;10(1):6. doi: 10.1038/s41572-023-00490-x. PMID: 38272922
Human strongyloidiasis: complexities and pathways forward.
Buonfrate D, Bradbury RS, Watts MR, Bisoffi Z
Clin Microbiol Rev 2023 Dec 20;36(4):e0003323. Epub 2023 Nov 8 doi: 10.1128/cmr.00033-23. PMID: 37937980Free PMC Article
Imported onchocerciasis in migrants and travelers.
Showler AJ, Nutman TB
Curr Opin Infect Dis 2018 Oct;31(5):393-398. doi: 10.1097/QCO.0000000000000483. PMID: 30113326Free PMC Article
Pharmacotherapy of ascariasis.
St Georgiev V
Expert Opin Pharmacother 2001 Feb;2(2):223-39. doi: 10.1517/14656566.2.2.223. PMID: 11336582

Prognosis

Human dirofilariosis in Austria: the past, the present, the future.
Riebenbauer K, Weber PB, Walochnik J, Karlhofer F, Winkler S, Dorfer S, Auer H, Valencak J, Laimer M, Handisurya A
Parasit Vectors 2021 Apr 29;14(1):227. doi: 10.1186/s13071-021-04696-4. PMID: 33926526Free PMC Article
Imported onchocerciasis in migrants and travelers.
Showler AJ, Nutman TB
Curr Opin Infect Dis 2018 Oct;31(5):393-398. doi: 10.1097/QCO.0000000000000483. PMID: 30113326Free PMC Article
Factors affecting onchocerciasis transmission: lessons for infection control.
Cheke RA
Expert Rev Anti Infect Ther 2017 Apr;15(4):377-386. Epub 2017 Feb 3 doi: 10.1080/14787210.2017.1286980. PMID: 28117596
Mucocutaneous manifestations of helminth infections: Nematodes.
Lupi O, Downing C, Lee M, Pino L, Bravo F, Giglio P, Sethi A, Klaus S, Sangueza OP, Fuller C, Mendoza N, Ladizinski B, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):929-44; quiz 945-6. doi: 10.1016/j.jaad.2014.11.034. PMID: 26568337
Role of pathogens in multiple sclerosis.
Libbey JE, Cusick MF, Fujinami RS
Int Rev Immunol 2014 Jul-Aug;33(4):266-83. Epub 2013 Nov 22 doi: 10.3109/08830185.2013.823422. PMID: 24266364Free PMC Article

Clinical prediction guides

Clinical and laboratory features of Strongyloides stercoralis infection at diagnosis and after treatment: a systematic review and meta-analysis.
Buonfrate D, Fittipaldo A, Vlieghe E, Bottieau E
Clin Microbiol Infect 2021 Nov;27(11):1621-1628. Epub 2021 Jul 26 doi: 10.1016/j.cmi.2021.07.016. PMID: 34325063
Human dirofilariosis in Austria: the past, the present, the future.
Riebenbauer K, Weber PB, Walochnik J, Karlhofer F, Winkler S, Dorfer S, Auer H, Valencak J, Laimer M, Handisurya A
Parasit Vectors 2021 Apr 29;14(1):227. doi: 10.1186/s13071-021-04696-4. PMID: 33926526Free PMC Article
Behavioural and clinical predictors for Loiasis.
Mischlinger J, Veletzky L, Tazemda-Kuitsouc GB, Pitzinger P, Matsegui PB, Gmeiner M, Lagler H, Gebru T, Held J, Mordmüller B, Ramharter M
J Glob Health 2018 Jun;8(1):010413. doi: 10.7189/jogh.08.010413. PMID: 29497506Free PMC Article
Factors affecting onchocerciasis transmission: lessons for infection control.
Cheke RA
Expert Rev Anti Infect Ther 2017 Apr;15(4):377-386. Epub 2017 Feb 3 doi: 10.1080/14787210.2017.1286980. PMID: 28117596
Immunity to helminths: resistance, regulation, and susceptibility to gastrointestinal nematodes.
Grencis RK
Annu Rev Immunol 2015;33:201-25. Epub 2014 Dec 17 doi: 10.1146/annurev-immunol-032713-120218. PMID: 25533702

Recent systematic reviews

Severe strongyloidiasis: a systematic review and meta-analysis of 339 cases.
Rojas OC, Montoya AM, Villanueva-Lozano H, Carrion-Alvarez D
Trans R Soc Trop Med Hyg 2023 Oct 3;117(10):682-696. doi: 10.1093/trstmh/trad032. PMID: 37300462
Global prevalence of Trichinella in pigs: A systematic review and meta-analysis.
Eslahi AV, KarimiPourSaryazdi A, Olfatifar M, de Carvalho LMM, Foroutan M, Karim MR, Badri M, Ketzis JK
Vet Med Sci 2022 Nov;8(6):2466-2481. Epub 2022 Sep 22 doi: 10.1002/vms3.951. PMID: 36137293Free PMC Article
Global prevalence and epidemiology of Strongyloides stercoralis in dogs: a systematic review and meta-analysis.
Eslahi AV, Hashemipour S, Olfatifar M, Houshmand E, Hajialilo E, Mahmoudi R, Badri M, Ketzis JK
Parasit Vectors 2022 Jan 10;15(1):21. doi: 10.1186/s13071-021-05135-0. PMID: 35012614Free PMC Article
Human dirofilariosis in Austria: the past, the present, the future.
Riebenbauer K, Weber PB, Walochnik J, Karlhofer F, Winkler S, Dorfer S, Auer H, Valencak J, Laimer M, Handisurya A
Parasit Vectors 2021 Apr 29;14(1):227. doi: 10.1186/s13071-021-04696-4. PMID: 33926526Free PMC Article
Toxocara spp. infection and risk of childhood asthma: A systematic review and meta-analysis.
Aghaei S, Riahi SM, Rostami A, Mohammadzadeh I, Javanian M, Tohidi E, Foroutan M, Esmaeili Dooki M
Acta Trop 2018 Jun;182:298-304. Epub 2018 Mar 21 doi: 10.1016/j.actatropica.2018.03.022. PMID: 29573999

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...