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Nematoda infectious disease

MedGen UID:
45025
•Concept ID:
C0027583
•
Disease or Syndrome
Synonyms: Infection, Nematode; Infections, Nematode; Nematode Infection; Nematode Infections
SNOMED CT: Nematode infection (84706005); Nematodiasis (84706005); Disease due to Nematoda (84706005)
 
Monarch Initiative: MONDO:0005871

Definition

Infections caused by nematode larvae which never develop into the adult stage and migrate through various body tissues. They commonly infect the skin, eyes, and viscera in humans. Ancylostoma brasiliensis causes cutaneous larva migrans. Toxocara causes visceral larva migrans. [from MONDO]

Professional guidelines

PubMed

Angiostrongylus cantonensis in travelers: clinical manifestations, diagnosis, and treatment.
Ansdell V, Wattanagoon Y
Curr Opin Infect Dis 2018 Oct;31(5):399-408. doi: 10.1097/QCO.0000000000000481. PMID: 30138142
Trichinella spiralis and Tumors: Cause, Coincidence or Treatment?
Liao C, Cheng X, Liu M, Wang X, Boireau P
Anticancer Agents Med Chem 2018;18(8):1091-1099. doi: 10.2174/1871520617666171121115847. PMID: 29173187Free PMC Article
Treatment of onchocerciasis.
Van Laethem Y, Lopes C
Drugs 1996 Dec;52(6):861-9. doi: 10.2165/00003495-199652060-00007. PMID: 8957156

Recent clinical studies

Etiology

Strongyloidiasis-related lung involvement: too much of a bad thing.
Barkati S, Greenaway C, Libman M
Curr Opin Infect Dis 2023 Jun 1;36(3):203-208. Epub 2023 Mar 28 doi: 10.1097/QCO.0000000000000915. PMID: 37093059
Neutrophils: Friend or foe in Filariasis?
Ajendra J, Allen JE
Parasite Immunol 2022 Jun;44(6):e12918. Epub 2022 May 25 doi: 10.1111/pim.12918. PMID: 35373850
Cellular context of IL-33 expression dictates impact on anti-helminth immunity.
Hung LY, Tanaka Y, Herbine K, Pastore C, Singh B, Ferguson A, Vora N, Douglas B, Zullo K, Behrens EM, Li Hui Tan T, Kohanski MA, Bryce P, Lin C, Kambayashi T, Reed DR, Brown BL, Cohen NA, Herbert DR
Sci Immunol 2020 Nov 13;5(53) doi: 10.1126/sciimmunol.abc6259. PMID: 33188058Free PMC Article
Imported onchocerciasis in migrants and travelers.
Showler AJ, Nutman TB
Curr Opin Infect Dis 2018 Oct;31(5):393-398. doi: 10.1097/QCO.0000000000000483. PMID: 30113326
Foodborne anisakiasis and allergy.
Baird FJ, Gasser RB, Jabbar A, Lopata AL
Mol Cell Probes 2014 Aug;28(4):167-74. Epub 2014 Feb 27 doi: 10.1016/j.mcp.2014.02.003. PMID: 24583228

Diagnosis

Strongyloides stercoralis.
Czeresnia JM, Weiss LM
Lung 2022 Apr;200(2):141-148. Epub 2022 Apr 9 doi: 10.1007/s00408-022-00528-z. PMID: 35396957Free PMC Article
Human gnathostomiasis: a neglected food-borne zoonosis.
Liu GH, Sun MM, Elsheikha HM, Fu YT, Sugiyama H, Ando K, Sohn WM, Zhu XQ, Yao C
Parasit Vectors 2020 Dec 9;13(1):616. doi: 10.1186/s13071-020-04494-4. PMID: 33298141Free PMC Article
The Pathogenesis of Nodding Syndrome.
Johnson TP, Sejvar J, Nutman TB, Nath A
Annu Rev Pathol 2020 Jan 24;15:395-417. doi: 10.1146/annurev-pathmechdis-012419-032748. PMID: 31977293
Toxocariasis: a silent threat with a progressive public health impact.
Chen J, Liu Q, Liu GH, Zheng WB, Hong SJ, Sugiyama H, Zhu XQ, Elsheikha HM
Infect Dis Poverty 2018 Jun 13;7(1):59. doi: 10.1186/s40249-018-0437-0. PMID: 29895324Free PMC Article
Human toxocariasis.
Ma G, Holland CV, Wang T, Hofmann A, Fan CK, Maizels RM, Hotez PJ, Gasser RB
Lancet Infect Dis 2018 Jan;18(1):e14-e24. Epub 2017 Aug 3 doi: 10.1016/S1473-3099(17)30331-6. PMID: 28781085

Therapy

Important Nematodes in Children.
Veesenmeyer AF
Pediatr Clin North Am 2022 Feb;69(1):129-139. doi: 10.1016/j.pcl.2021.08.005. PMID: 34794670
Genome editing as control tool for filarial infections.
Kwarteng A, Sylverken A, Asiedu E, Ahuno ST
Biomed Pharmacother 2021 May;137:111292. Epub 2021 Feb 10 doi: 10.1016/j.biopha.2021.111292. PMID: 33581654
Imported onchocerciasis in migrants and travelers.
Showler AJ, Nutman TB
Curr Opin Infect Dis 2018 Oct;31(5):393-398. doi: 10.1097/QCO.0000000000000483. PMID: 30113326
Heartworm disease in animals and humans.
McCall JW, Genchi C, Kramer LH, Guerrero J, Venco L
Adv Parasitol 2008;66:193-285. doi: 10.1016/S0065-308X(08)00204-2. PMID: 18486691
Ascariasis and hookworm.
Sarinas PS, Chitkara RK
Semin Respir Infect 1997 Jun;12(2):130-7. PMID: 9195678

Prognosis

Human dirofilariosis in Austria: the past, the present, the future.
Riebenbauer K, Weber PB, Walochnik J, Karlhofer F, Winkler S, Dorfer S, Auer H, Valencak J, Laimer M, Handisurya A
Parasit Vectors 2021 Apr 29;14(1):227. doi: 10.1186/s13071-021-04696-4. PMID: 33926526Free PMC Article
Imported onchocerciasis in migrants and travelers.
Showler AJ, Nutman TB
Curr Opin Infect Dis 2018 Oct;31(5):393-398. doi: 10.1097/QCO.0000000000000483. PMID: 30113326
Role of miRNAs in development and disease: Lessons learnt from small organisms.
Chandra S, Vimal D, Sharma D, Rai V, Gupta SC, Chowdhuri DK
Life Sci 2017 Sep 15;185:8-14. Epub 2017 Jul 17 doi: 10.1016/j.lfs.2017.07.017. PMID: 28728902
Central nervous system manifestations of Angiostrongylus cantonensis infection.
Martins YC, Tanowitz HB, Kazacos KR
Acta Trop 2015 Jan;141(Pt A):46-53. Epub 2014 Oct 13 doi: 10.1016/j.actatropica.2014.10.002. PMID: 25312338Free PMC Article
Role of pathogens in multiple sclerosis.
Libbey JE, Cusick MF, Fujinami RS
Int Rev Immunol 2014 Jul-Aug;33(4):266-83. Epub 2013 Nov 22 doi: 10.3109/08830185.2013.823422. PMID: 24266364Free PMC Article

Clinical prediction guides

The current landscape of microRNAs (miRNAs) in bacterial pneumonia: opportunities and challenges.
Zhang F, Zhou Y, Ding J
Cell Mol Biol Lett 2022 Aug 19;27(1):70. doi: 10.1186/s11658-022-00368-y. PMID: 35986232Free PMC Article
Clinical and laboratory features of Strongyloides stercoralis infection at diagnosis and after treatment: a systematic review and meta-analysis.
Buonfrate D, Fittipaldo A, Vlieghe E, Bottieau E
Clin Microbiol Infect 2021 Nov;27(11):1621-1628. Epub 2021 Jul 26 doi: 10.1016/j.cmi.2021.07.016. PMID: 34325063
Human dirofilariosis in Austria: the past, the present, the future.
Riebenbauer K, Weber PB, Walochnik J, Karlhofer F, Winkler S, Dorfer S, Auer H, Valencak J, Laimer M, Handisurya A
Parasit Vectors 2021 Apr 29;14(1):227. doi: 10.1186/s13071-021-04696-4. PMID: 33926526Free PMC Article
Behavioural and clinical predictors for Loiasis.
Mischlinger J, Veletzky L, Tazemda-Kuitsouc GB, Pitzinger P, Matsegui PB, Gmeiner M, Lagler H, Gebru T, Held J, Mordmüller B, Ramharter M
J Glob Health 2018 Jun;8(1):010413. doi: 10.7189/jogh.08.010413. PMID: 29497506Free PMC Article
Factors affecting onchocerciasis transmission: lessons for infection control.
Cheke RA
Expert Rev Anti Infect Ther 2017 Apr;15(4):377-386. Epub 2017 Feb 3 doi: 10.1080/14787210.2017.1286980. PMID: 28117596

Recent systematic reviews

Global prevalence of Trichinella in pigs: A systematic review and meta-analysis.
Eslahi AV, KarimiPourSaryazdi A, Olfatifar M, de Carvalho LMM, Foroutan M, Karim MR, Badri M, Ketzis JK
Vet Med Sci 2022 Nov;8(6):2466-2481. Epub 2022 Sep 22 doi: 10.1002/vms3.951. PMID: 36137293Free PMC Article
The prevalence of human trichuriasis in Asia: a systematic review and meta-analysis.
Badri M, Olfatifar M, Wandra T, Budke CM, Mahmoudi R, Abdoli A, Hajialilo E, Pestehchian N, Ghaffarifar F, Foroutan M, Hashemipour S, Sotoodeh S, Samimi R, Eslahi AV
Parasitol Res 2022 Jan;121(1):1-10. Epub 2022 Jan 6 doi: 10.1007/s00436-021-07365-8. PMID: 34993634
Clinical and laboratory features of Strongyloides stercoralis infection at diagnosis and after treatment: a systematic review and meta-analysis.
Buonfrate D, Fittipaldo A, Vlieghe E, Bottieau E
Clin Microbiol Infect 2021 Nov;27(11):1621-1628. Epub 2021 Jul 26 doi: 10.1016/j.cmi.2021.07.016. PMID: 34325063
Human dirofilariosis in Austria: the past, the present, the future.
Riebenbauer K, Weber PB, Walochnik J, Karlhofer F, Winkler S, Dorfer S, Auer H, Valencak J, Laimer M, Handisurya A
Parasit Vectors 2021 Apr 29;14(1):227. doi: 10.1186/s13071-021-04696-4. PMID: 33926526Free PMC Article
Toxocara spp. infection and risk of childhood asthma: A systematic review and meta-analysis.
Aghaei S, Riahi SM, Rostami A, Mohammadzadeh I, Javanian M, Tohidi E, Foroutan M, Esmaeili Dooki M
Acta Trop 2018 Jun;182:298-304. Epub 2018 Mar 21 doi: 10.1016/j.actatropica.2018.03.022. PMID: 29573999

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