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Stenosis

MedGen UID:: 224710
•Concept ID:: C1261287
•: Pathologic Function

Synonyms:	Constriction, Pathologic; Constriction, Pathological; Constrictions, Pathologic; Pathologic Constriction; Pathologic Constrictions; Pathological Constriction; Stenoses; Stricture; Strictures
SNOMED CT:	Stenosis (415582006); Stricture (27551008); Constriction (27551008)

Definition

Narrowing or stricture of a vessel, duct or canal. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVStenosis

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Non-Neoplastic Disorder
      - Non-Neoplastic Disorder by Special Category
        Deformity
        Stenosis
        Bronchial Stricture
        Gastrointestinal stenosis
        Anal stenosis
        Colonic stenosis
        Esophageal stricture
        Esophageal anastomotic stricture
        Radiation-induced stricture of esophagus
        Gastrointestinal Stoma Stenosis
        Pancreatic Duct Stenosis
        Small intestinal stenosis
        Duodenal stenosis
        Stenosis of jejunum
        Stricture of ileum
        Stenosis of bile duct
        Stenosis of rectum
        Stenosis of stomach
        Stricture of intestine
        In Stent Restenosis
        Laryngeal stenosis
        Pharyngeal stenosis
        Reproductive System Stenosis
        Spermatic Cord Stenosis
        Uterine Cervical Stenosis
        Vaginal stricture
        Vas Deferens Stenosis
        Restenosis
        Tracheal stenosis
        Laryngotracheal stenosis
        Tracheal atresia
        Urinary Tract Stenosis
        Stenosis of bladder neck
        Stricture of ureter
        Ureteral stenosis
        Ureteropelvic junction obstruction
        Ureterovesical stenosis
        Urethral stricture
        Bulbar urethral stricture
        Fossa navicularis urethral stricture
        Pendulous urethral stricture
        Urostomy Stenosis
        Valvular Stenosis
        Aortic valve stenosis
        Subvalvular aortic stenosis
        Supravalvar aortic stenosis
        Mild Cardiac Valve Stenosis
        Mitral stenosis
        Congenital mitral stenosis
        Moderate Cardiac Valve Stenosis
        Pulmonic stenosis
        Subpulmonary stenosis
        Supravalvular pulmonary stenosis
        Valvular pulmonary stenosis
        Severe Cardiac Valve Stenosis
        Tricuspid stenosis
        Vascular Stenosis
        Arteriovenous graft stenosis
        Coronary artery stenosis
        Coronary restenosis
        Left Main Coronary Artery Stenosis
        Proximal Left Anterior Descending Coronary Artery Stenosis
        Venous stenosis
        Inferior vena cava stenosis
        Pulmonary vein stenosis
        Subclavian vein stenosis
        Superior vena cava stenosis

Professional guidelines

PubMed

Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement.

Kronenberg F, Mora S, Stroes ESG, Ference BA, Arsenault BJ, Berglund L, Dweck MR, Koschinsky M, Lambert G, Mach F, McNeal CJ, Moriarty PM, Natarajan P, Nordestgaard BG, Parhofer KG, Virani SS, von Eckardstein A, Watts GF, Stock JK, Ray KK, Tokgözoğlu LS, Catapano AL
Eur Heart J 2022 Oct 14;43(39):3925-3946. doi: 10.1093/eurheartj/ehac361. PMID: 36036785 Free PMC Article

Evidence-based clinical practice guidelines for peptic ulcer disease 2020.

Kamada T, Satoh K, Itoh T, Ito M, Iwamoto J, Okimoto T, Kanno T, Sugimoto M, Chiba T, Nomura S, Mieda M, Hiraishi H, Yoshino J, Takagi A, Watanabe S, Koike K
J Gastroenterol 2021 Apr;56(4):303-322. Epub 2021 Feb 23 doi: 10.1007/s00535-021-01769-0. PMID: 33620586 Free PMC Article

2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Otto CM, Nishimura RA, Bonow RO, Carabello BA, Erwin JP 3rd, Gentile F, Jneid H, Krieger EV, Mack M, McLeod C, O'Gara PT, Rigolin VH, Sundt TM 3rd, Thompson A, Toly C
Circulation 2021 Feb 2;143(5):e35-e71. Epub 2020 Dec 17 doi: 10.1161/CIR.0000000000000932. PMID: 33332149

See all (5525)

Recent clinical studies

Etiology

Management of atherosclerotic extracranial carotid artery stenosis.

Bonati LH, Jansen O, de Borst GJ, Brown MM
Lancet Neurol 2022 Mar;21(3):273-283. doi: 10.1016/S1474-4422(21)00359-8. PMID: 35182512

A systematic review of developmental lumbar spinal stenosis.

Lai MKL, Cheung PWH, Cheung JPY
Eur Spine J 2020 Sep;29(9):2173-2187. Epub 2020 Jul 4 doi: 10.1007/s00586-020-06524-2. PMID: 32623513

Current concepts and recent advances in understanding and managing lumbar spine stenosis.

Bagley C, MacAllister M, Dosselman L, Moreno J, Aoun SG, El Ahmadieh TY
F1000Res 2019;8 Epub 2019 Jan 31 doi: 10.12688/f1000research.16082.1. PMID: 30774933 Free PMC Article

Aortic Stenosis: Diagnosis and Treatment.

Grimard BH, Safford RE, Burns EL
Am Fam Physician 2016 Mar 1;93(5):371-8. PMID: 26926974

Spinal stenosis.

Melancia JL, Francisco AF, Antunes JL
Handb Clin Neurol 2014;119:541-9. doi: 10.1016/B978-0-7020-4086-3.00035-7. PMID: 24365318

See all (79351)

Diagnosis

Valvular Heart Disease.

Kisling A, Gallagher R
Prim Care 2024 Mar;51(1):95-109. Epub 2023 Sep 7 doi: 10.1016/j.pop.2023.08.003. PMID: 38278576

Hypertrophic Pyloric Stenosis.

Rich BS, Dolgin SE
Pediatr Rev 2021 Oct;42(10):539-545. doi: 10.1542/pir.2020-003277. PMID: 34599053

Spinal stenosis.

Melancia JL, Francisco AF, Antunes JL
Handb Clin Neurol 2014;119:541-9. doi: 10.1016/B978-0-7020-4086-3.00035-7. PMID: 24365318

Lumbar spinal stenosis.

Ciricillo SF, Weinstein PR
West J Med 1993 Feb;158(2):171-7. PMID: 8434469 Free PMC Article

Pyloric stenosis.

Bissonnette B, Sullivan PJ
Can J Anaesth 1991 Jul;38(5):668-76. doi: 10.1007/BF03008206. PMID: 1934223

See all (57723)

Therapy

A Review of the Partner Trials.

Markham R, Sharma R
Interv Cardiol Clin 2020 Oct;9(4):461-467. doi: 10.1016/j.iccl.2020.07.002. PMID: 32921370

Statin therapy increases lipoprotein(a) levels.

Tsimikas S, Gordts PLSM, Nora C, Yeang C, Witztum JL
Eur Heart J 2020 Jun 21;41(24):2275-2284. doi: 10.1093/eurheartj/ehz310. PMID: 31111151

International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial: Rationale and design.

ISCHEMIA Trial Research Group, Maron DJ, Hochman JS, O'Brien SM, Reynolds HR, Boden WE, Stone GW, Bangalore S, Spertus JA, Mark DB, Alexander KP, Shaw L, Berger JS, Ferguson TB Jr, Williams DO, Harrington RA, Rosenberg Y
Am Heart J 2018 Jul;201:124-135. Epub 2018 Apr 21 doi: 10.1016/j.ahj.2018.04.011. PMID: 29778671 Free PMC Article

Surgery versus nonsurgical treatment of lumbar spinal stenosis: a randomized trial.

Delitto A, Piva SR, Moore CG, Fritz JM, Wisniewski SR, Josbeno DA, Fye M, Welch WC
Ann Intern Med 2015 Apr 7;162(7):465-73. doi: 10.7326/M14-1420. PMID: 25844995 Free PMC Article

The win ratio: a new approach to the analysis of composite endpoints in clinical trials based on clinical priorities.

Pocock SJ, Ariti CA, Collier TJ, Wang D
Eur Heart J 2012 Jan;33(2):176-82. Epub 2011 Sep 6 doi: 10.1093/eurheartj/ehr352. PMID: 21900289

See all (48897)

Prognosis

Minimally invasive surgical aortic valve replacement.

Jahangiri M, Hussain A, Akowuah E
Heart 2019 Mar;105(Suppl 2):s10-s15. doi: 10.1136/heartjnl-2018-313512. PMID: 30846519

UK TAVI registry.

Ludman PF
Heart 2019 Mar;105(Suppl 2):s2-s5. doi: 10.1136/heartjnl-2018-313510. PMID: 30846517

Echocardiographic follow-up after transcatheter aortic valve replacement.

Sokalskis V, Muraru D, Fraccaro C, Napodano M, D'Onofrio A, Tarantini G, Badano LP
Echocardiography 2017 Feb;34(2):267-278. Epub 2017 Jan 3 doi: 10.1111/echo.13443. PMID: 28052455

Frailty scoring in transcatheter aortic valve replacement patients.

Hinterbuchner L, Strohmer B, Hammerer M, Prinz E, Hoppe UC, Schernthaner C
Eur J Cardiovasc Nurs 2016 Oct;15(6):384-97. Epub 2015 Jul 27 doi: 10.1177/1474515115596640. PMID: 26216870

Alagille syndrome.

Hadchouel M
Indian J Pediatr 2002 Sep;69(9):815-8. doi: 10.1007/BF02723697. PMID: 12420916

See all (48744)

Clinical prediction guides

Is 3D ultrasound reliable for the evaluation of carotid disease? A systematic review and meta-analysis.

Sultan SR, Bashmail FT, Alzahrani NA, Alharbi SI, Anbar R, Alkharaiji M
Med Ultrason 2023 Jun 26;25(2):216-223. Epub 2022 Nov 22 doi: 10.11152/mu-3731. PMID: 36546363

Reliability and Accuracy of Tomographic 3-D Ultrasound for Grading Vessel Stenosis: A Phantom Study.

Alzahrani A, Alotaibi SA, Aslam M, Sultan SR
Ultrasound Med Biol 2022 Sep;48(9):1899-1906. Epub 2022 Jun 14 doi: 10.1016/j.ultrasmedbio.2022.05.020. PMID: 35715330

Clinical Relevance of Coronary Computed Tomography Angiography Beyond Coronary Artery Stenosis.

Meah MN, Williams MC
Rofo 2021 Oct;193(10):1162-1170. Epub 2021 Mar 26 doi: 10.1055/a-1395-7905. PMID: 33772488

Comparison of Measurement and Grading of Carotid Stenosis with Computed Tomography Angiography and Doppler Ultrasound.

Birmpili P, Porter L, Shaikh U, Torella F
Ann Vasc Surg 2018 Aug;51:217-224. Epub 2018 Mar 6 doi: 10.1016/j.avsg.2018.01.102. PMID: 29522870

Development and validation of a new, simplified endoscopic activity score for Crohn's disease: the SES-CD.

Daperno M, D'Haens G, Van Assche G, Baert F, Bulois P, Maunoury V, Sostegni R, Rocca R, Pera A, Gevers A, Mary JY, Colombel JF, Rutgeerts P
Gastrointest Endosc 2004 Oct;60(4):505-12. doi: 10.1016/s0016-5107(04)01878-4. PMID: 15472670

See all (44648)

Recent systematic reviews

Society for Vascular Surgery clinical practice guidelines for management of extracranial cerebrovascular disease.

AbuRahma AF, Avgerinos ED, Chang RW, Darling RC 3rd, Duncan AA, Forbes TL, Malas MB, Murad MH, Perler BA, Powell RJ, Rockman CB, Zhou W
J Vasc Surg 2022 Jan;75(1S):4S-22S. Epub 2021 Jun 19 doi: 10.1016/j.jvs.2021.04.073. PMID: 34153348

A systematic review of developmental lumbar spinal stenosis.

Lai MKL, Cheung PWH, Cheung JPY
Eur Spine J 2020 Sep;29(9):2173-2187. Epub 2020 Jul 4 doi: 10.1007/s00586-020-06524-2. PMID: 32623513

Medical Treatment of Aortic Stenosis.

Marquis-Gravel G, Redfors B, Leon MB, Généreux P
Circulation 2016 Nov 29;134(22):1766-1784. doi: 10.1161/CIRCULATIONAHA.116.023997. PMID: 27895025

Surgical versus non-surgical treatment for lumbar spinal stenosis.

Zaina F, Tomkins-Lane C, Carragee E, Negrini S
Cochrane Database Syst Rev 2016 Jan 29;2016(1):CD010264. doi: 10.1002/14651858.CD010264.pub2. PMID: 26824399 Free PMC Article

Management of lumbar spinal stenosis.

Lurie J, Tomkins-Lane C
BMJ 2016 Jan 4;352:h6234. doi: 10.1136/bmj.h6234. PMID: 26727925 Free PMC Article

See all (1963)

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