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Viral hepatitis

MedGen UID:
22652
Concept ID:
C0042721
Disease or Syndrome
Synonyms: Hepatitis viral; human viral hepatitis; VH - Viral hepatitis; Viral Hepatitis; viral hepatitis; viral Hepatitis; viral human hepatitis; Viruses caused hepatitis; Viruses hepatitis
SNOMED CT: VH - Viral hepatitis (3738000); Viral hepatitis (3738000)
 
HPO: HP:0006562
Monarch Initiative: MONDO:0006011

Definition

Inflammation of the liver due to infection with a virus. [from HPO]

Conditions with this feature

MHC class II deficiency
MedGen UID:
444051
Concept ID:
C2931418
Disease or Syndrome
A rare autosomal recessive primary immunodeficiency characterized by absence of HLA class II molecules on the surface of immune cells, leading to severely impaired cellular and humoral immune response to foreign antigens, severe CD4+ T-cell lymphopenia, and hypogammaglobulinemia. The disease clinically manifests with early onset of severe and recurrent infections mainly of the respiratory and gastrointestinal tract, protracted diarrhea with failure to thrive, and autoimmune disease, and is frequently fatal in childhood.

Professional guidelines

PubMed

Smith A, Baumgartner K, Bositis C
Am Fam Physician 2019 Dec 15;100(12):759-770. PMID: 31845776
Yang JD, Hainaut P, Gores GJ, Amadou A, Plymoth A, Roberts LR
Nat Rev Gastroenterol Hepatol 2019 Oct;16(10):589-604. Epub 2019 Aug 22 doi: 10.1038/s41575-019-0186-y. PMID: 31439937Free PMC Article
Kwo PY, Cohen SM, Lim JK
Am J Gastroenterol 2017 Jan;112(1):18-35. Epub 2016 Dec 20 doi: 10.1038/ajg.2016.517. PMID: 27995906

Recent clinical studies

Etiology

Zhang L, Zi L, Kuang T, Wang K, Qiu Z, Wu Z, Liu L, Liu R, Wang P, Wang W
Front Endocrinol (Lausanne) 2023;14:1159148. Epub 2023 Jul 5 doi: 10.3389/fendo.2023.1159148. PMID: 37476494Free PMC Article
Lloyd AR, Franco RA
Infect Dis Clin North Am 2023 Jun;37(2):335-349. doi: 10.1016/j.idc.2023.02.010. PMID: 37105646
Shata MTM, Hetta HF, Sharma Y, Sherman KE
J Viral Hepat 2022 Oct;29(10):844-861. Epub 2022 Jul 7 doi: 10.1111/jvh.13725. PMID: 35748741Free PMC Article
Tagkou NM, Kondylis G, Cholongitas E
Curr Pharm Des 2021;27(36):3775-3785. doi: 10.2174/1381612826666201210113841. PMID: 33302848
Jarcuska P, Abdel-Razik A, Flisiak R, Singh RB
Can J Gastroenterol Hepatol 2018;2018:7369314. Epub 2018 Nov 4 doi: 10.1155/2018/7369314. PMID: 30519548Free PMC Article

Diagnosis

Pisano MB, Giadans CG, Flichman DM, Ré VE, Preciado MV, Valva P
World J Gastroenterol 2021 Jul 14;27(26):4018-4044. doi: 10.3748/wjg.v27.i26.4018. PMID: 34326611Free PMC Article
Castaneda D, Gonzalez AJ, Alomari M, Tandon K, Zervos XB
World J Gastroenterol 2021 Apr 28;27(16):1691-1715. doi: 10.3748/wjg.v27.i16.1691. PMID: 33967551Free PMC Article
Bunchorntavakul C, Reddy KR
Gastroenterol Clin North Am 2020 Jun;49(2):331-346. doi: 10.1016/j.gtc.2020.01.008. PMID: 32389366
Hardikar W
J Paediatr Child Health 2019 Sep;55(9):1038-1043. Epub 2019 Jul 17 doi: 10.1111/jpc.14562. PMID: 31317618
Gregorio GV, Mieli-Vergani G, Mowat AP
Arch Dis Child 1994 Apr;70(4):343-8. doi: 10.1136/adc.70.4.343. PMID: 8185372Free PMC Article

Therapy

Friedman SL, Pinzani M
Hepatology 2022 Feb;75(2):473-488. Epub 2022 Jan 11 doi: 10.1002/hep.32285. PMID: 34923653
Haber PK, Puigvehí M, Castet F, Lourdusamy V, Montal R, Tabrizian P, Buckstein M, Kim E, Villanueva A, Schwartz M, Llovet JM
Gastroenterology 2021 Sep;161(3):879-898. Epub 2021 Jun 12 doi: 10.1053/j.gastro.2021.06.008. PMID: 34126063
Abenavoli L, Izzo AA, Milić N, Cicala C, Santini A, Capasso R
Phytother Res 2018 Nov;32(11):2202-2213. Epub 2018 Aug 6 doi: 10.1002/ptr.6171. PMID: 30080294
Al-Khalili A, Dutz JP
Curr Probl Dermatol 2018;53:28-36. Epub 2017 Nov 7 doi: 10.1159/000478076. PMID: 29131035
Abenavoli L, Capasso R, Milic N, Capasso F
Phytother Res 2010 Oct;24(10):1423-32. doi: 10.1002/ptr.3207. PMID: 20564545

Prognosis

Riazi K, Azhari H, Charette JH, Underwood FE, King JA, Afshar EE, Swain MG, Congly SE, Kaplan GG, Shaheen AA
Lancet Gastroenterol Hepatol 2022 Sep;7(9):851-861. Epub 2022 Jul 5 doi: 10.1016/S2468-1253(22)00165-0. PMID: 35798021
Paik JM, Kabbara K, Eberly KE, Younossi Y, Henry L, Younossi ZM
Hepatology 2022 May;75(5):1204-1217. Epub 2021 Dec 21 doi: 10.1002/hep.32228. PMID: 34741554
Terrault NA, Levy MT, Cheung KW, Jourdain G
Nat Rev Gastroenterol Hepatol 2021 Feb;18(2):117-130. Epub 2020 Oct 12 doi: 10.1038/s41575-020-00361-w. PMID: 33046891
Sarin SK, Kumar M, Eslam M, George J, Al Mahtab M, Akbar SMF, Jia J, Tian Q, Aggarwal R, Muljono DH, Omata M, Ooka Y, Han KH, Lee HW, Jafri W, Butt AS, Chong CH, Lim SG, Pwu RF, Chen DS
Lancet Gastroenterol Hepatol 2020 Feb;5(2):167-228. Epub 2019 Dec 15 doi: 10.1016/S2468-1253(19)30342-5. PMID: 31852635Free PMC Article
Asrani SK, Devarbhavi H, Eaton J, Kamath PS
J Hepatol 2019 Jan;70(1):151-171. Epub 2018 Sep 26 doi: 10.1016/j.jhep.2018.09.014. PMID: 30266282

Clinical prediction guides

Fan R, Chen L, Zhao S, Yang H, Li Z, Qian Y, Ma H, Liu X, Wang C, Liang X, Bai J, Xie J, Fan X, Xie Q, Hao X, Wang C, Yang S, Gao Y, Bai H, Dou X, Liu J, Wu L, Jiang G, Xia Q, Zheng D, Rao H, Xia J, Shang J, Gao P, Xie D, Yu Y, Yang Y, Gao H, Liu Y, Sun A, Jiang Y, Yu Y, Niu J, Sun J, Wang H, Hou J
J Hepatol 2023 Oct;79(4):933-944. Epub 2023 Jun 10 doi: 10.1016/j.jhep.2023.05.039. PMID: 37302583
Fan R, Papatheodoridis G, Sun J, Innes H, Toyoda H, Xie Q, Mo S, Sypsa V, Guha IN, Kumada T, Niu J, Dalekos G, Yasuda S, Barnes E, Lian J, Suri V, Idilman R, Barclay ST, Dou X, Berg T, Hayes PC, Flaherty JF, Zhou Y, Zhang Z, Buti M, Hutchinson SJ, Guo Y, Calleja JL, Lin L, Zhao L, Chen Y, Janssen HLA, Zhu C, Shi L, Tang X, Gaggar A, Wei L, Jia J, Irving WL, Johnson PJ, Lampertico P, Hou J
J Hepatol 2020 Dec;73(6):1368-1378. Epub 2020 Jul 21 doi: 10.1016/j.jhep.2020.07.025. PMID: 32707225
Smith A, Baumgartner K, Bositis C
Am Fam Physician 2019 Dec 15;100(12):759-770. PMID: 31845776
Hernaez R, Solà E, Moreau R, Ginès P
Gut 2017 Mar;66(3):541-553. Epub 2017 Jan 4 doi: 10.1136/gutjnl-2016-312670. PMID: 28053053Free PMC Article
Sookoian S, Pirola CJ
World J Gastroenterol 2015 Jan 21;21(3):711-25. doi: 10.3748/wjg.v21.i3.711. PMID: 25624707Free PMC Article

Recent systematic reviews

Im YR, Jagdish R, Leith D, Kim JU, Yoshida K, Majid A, Ge Y, Ndow G, Shimakawa Y, Lemoine M
Lancet Gastroenterol Hepatol 2022 Oct;7(10):932-942. Epub 2022 Aug 10 doi: 10.1016/S2468-1253(22)00201-1. PMID: 35961359Free PMC Article
Riazi K, Azhari H, Charette JH, Underwood FE, King JA, Afshar EE, Swain MG, Congly SE, Kaplan GG, Shaheen AA
Lancet Gastroenterol Hepatol 2022 Sep;7(9):851-861. Epub 2022 Jul 5 doi: 10.1016/S2468-1253(22)00165-0. PMID: 35798021
Haber PK, Puigvehí M, Castet F, Lourdusamy V, Montal R, Tabrizian P, Buckstein M, Kim E, Villanueva A, Schwartz M, Llovet JM
Gastroenterology 2021 Sep;161(3):879-898. Epub 2021 Jun 12 doi: 10.1053/j.gastro.2021.06.008. PMID: 34126063
Leidner AJ, Murthy N, Chesson HW, Biggerstaff M, Stoecker C, Harris AM, Acosta A, Dooling K, Bridges CB
Vaccine 2019 Jan 7;37(2):226-234. Epub 2018 Dec 4 doi: 10.1016/j.vaccine.2018.11.056. PMID: 30527660Free PMC Article
Patel P, Borkowf CB, Brooks JT, Lasry A, Lansky A, Mermin J
AIDS 2014 Jun 19;28(10):1509-19. doi: 10.1097/QAD.0000000000000298. PMID: 24809629Free PMC Article

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