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AIDS-Related Malignant Cervical Neoplasm

MedGen UID:
231006
•Concept ID:
C1332050
•
Neoplastic Process
Synonyms: AIDS-Related Malignant Cervical Tumor; AIDS-Related Malignant Cervix Neoplasm; AIDS-Related Malignant Cervix Tumor; AIDS-Related Malignant Cervix Uteri Neoplasm; AIDS-Related Malignant Cervix Uteri Tumor; AIDS-Related Malignant Neoplasm of Cervix; AIDS-Related Malignant Neoplasm of Cervix Uteri; AIDS-Related Malignant Neoplasm of the Cervix; AIDS-Related Malignant Neoplasm of the Cervix Uteri; AIDS-Related Malignant Neoplasm of the Uterine Cervix; AIDS-Related Malignant Neoplasm of Uterine Cervix; AIDS-Related Malignant Tumor of Cervix; AIDS-Related Malignant Tumor of Cervix Uteri; AIDS-Related Malignant Tumor of the Cervix; AIDS-Related Malignant Tumor of the Cervix Uteri; AIDS-Related Malignant Tumor of the Uterine Cervix; AIDS-Related Malignant Tumor of Uterine Cervix; AIDS-Related Malignant Uterine Cervix Neoplasm; AIDS-Related Malignant Uterine Cervix Tumor

Definition

A malignant neoplasm that arises from the cervix in a patient with acquired immunodeficiency syndrome. This category includes cervical carcinoma, Kaposi sarcoma, and non-Hodgkin lymphoma. [from NCI]

Professional guidelines

PubMed

HIV Infection in Adults: Initial Management.
Goldschmidt R, Chu C
Am Fam Physician 2021 Apr 1;103(7):407-416. PMID: 33788514
British HIV Association guidelines for HIV-associated malignancies 2014.
Bower M, Palfreeman A, Alfa-Wali M, Bunker C, Burns F, Churchill D, Collins S, Cwynarski K, Edwards S, Fields P, Fife K, Gallop-Evans E, Kassam S, Kulasegaram R, Lacey C, Marcus R, Montoto S, Nelson M, Newsom-Davis T, Orkin C, Shaw K, Tenant-Flowers M, Webb A, Westwell S, Williams M; British HIV Association
HIV Med 2014 Mar;15 Suppl 2:1-92. doi: 10.1111/hiv.12136. PMID: 24528810
British HIV Association guidelines for HIV-associated malignancies 2008.
Bower M, Collins S, Cottrill C, Cwynarski K, Montoto S, Nelson M, Nwokolo N, Powles T, Stebbing J, Wales N, Webb A; AIDS Malignancy Subcommittee
HIV Med 2008 Jul;9(6):336-88. doi: 10.1111/j.1468-1293.2008.00608.x. PMID: 18705759

Recent clinical studies

Etiology

Squamous Carcinoma of the Cervix in a 15-Year-Old with Congenital HIV: A Case Report.
Evans M, Lawson A, Jarin JD, Wilson EE
J Pediatr Adolesc Gynecol 2021 Apr;34(2):234-237. Epub 2020 Sep 8 doi: 10.1016/j.jpag.2020.08.014. PMID: 32916302
Chapter 6: Immunosuppression and co-infection with HIV.
Palefsky JM, Holly EA
J Natl Cancer Inst Monogr 2003;(31):41-6. doi: 10.1093/oxfordjournals.jncimonographs.a003481. PMID: 12807944
Lower genital tract neoplasia in women with HIV infection.
Abercrombie PD, Korn AP
Oncology (Williston Park) 1998 Dec;12(12):1735-9; discussion 1742, 1745, 1747. PMID: 9874847
Opportunistic infections.
Vazquez E
Posit Aware 1996 Sep-Oct;7(5):12-3. PMID: 11363782
AIDS-associated malignancies.
Krown SE
Cancer Chemother Biol Response Modif 1996;16:441-61. PMID: 8639393

Diagnosis

AIDS-related cancers increase in Africa.
Brower V
J Natl Cancer Inst 2011 Jun 22;103(12):918-9. doi: 10.1093/jnci/djr235. PMID: 21693755
Neoplastic complications of HIV infection.
Spina M, Vaccher E, Carbone A, Tirelli U
Ann Oncol 1999 Nov;10(11):1271-86. doi: 10.1023/a:1008390028330. PMID: 10631453
Lower genital tract neoplasia in women with HIV infection.
Abercrombie PD, Korn AP
Oncology (Williston Park) 1998 Dec;12(12):1735-9; discussion 1742, 1745, 1747. PMID: 9874847
Opportunistic infections.
Vazquez E
Posit Aware 1996 Sep-Oct;7(5):12-3. PMID: 11363782
AIDS-associated malignancies.
Krown SE
Cancer Chemother Biol Response Modif 1996;16:441-61. PMID: 8639393

Therapy

AIDS-related cancers increase in Africa.
Brower V
J Natl Cancer Inst 2011 Jun 22;103(12):918-9. doi: 10.1093/jnci/djr235. PMID: 21693755
The treatment of AIDS-related cancers.
Levine AM, Hancock BW, MacPhail P, Ruff P, Ashcroft RE
Lancet Oncol 2003 Sep;4(9):576-81. doi: 10.1016/s1470-2045(03)01198-7. PMID: 12965280
Gender differences and sex-specific manifestations associated with human immunodeficiency virus infection in women.
Gilad J, Walfisch A, Borer A, Schlaeffer F
Eur J Obstet Gynecol Reprod Biol 2003 Aug 15;109(2):199-205. doi: 10.1016/s0301-2115(03)00048-4. PMID: 12860342
Chapter 6: Immunosuppression and co-infection with HIV.
Palefsky JM, Holly EA
J Natl Cancer Inst Monogr 2003;(31):41-6. doi: 10.1093/oxfordjournals.jncimonographs.a003481. PMID: 12807944
Cancer and HIV infection.
Cottrill CP, Bottomley DM, Phillips RH
Clin Oncol (R Coll Radiol) 1997;9(6):365-80. doi: 10.1016/s0936-6555(97)80129-x. PMID: 9448965

Prognosis

AIDS-related cancers increase in Africa.
Brower V
J Natl Cancer Inst 2011 Jun 22;103(12):918-9. doi: 10.1093/jnci/djr235. PMID: 21693755
The impact of HIV antiviral therapy on human papillomavirus (HPV) infections and HPV-related diseases.
Heard I, Palefsky JM, Kazatchkine MD
Antivir Ther 2004 Feb;9(1):13-22. PMID: 15040532
Neoplastic complications of HIV infection.
Spina M, Vaccher E, Carbone A, Tirelli U
Ann Oncol 1999 Nov;10(11):1271-86. doi: 10.1023/a:1008390028330. PMID: 10631453
Opportunistic infections update.
Proj Inf Perspect 1998 Apr;(24):17-9. PMID: 11365715
AIDS-associated malignancies.
Krown SE
Cancer Chemother Biol Response Modif 1996;16:441-61. PMID: 8639393

Clinical prediction guides

Assessing the impact of HAART on the incidence of defining and non-defining AIDS cancers among patients with HIV/AIDS: a systematic review.
Cobucci RN, Lima PH, de Souza PC, Costa VV, Cornetta Mda C, Fernandes JV, Gonçalves AK
J Infect Public Health 2015 Jan-Feb;8(1):1-10. Epub 2014 Oct 5 doi: 10.1016/j.jiph.2014.08.003. PMID: 25294086
AIDS-related cancer and severity of immunosuppression in persons with AIDS.
Biggar RJ, Chaturvedi AK, Goedert JJ, Engels EA; HIV/AIDS Cancer Match Study
J Natl Cancer Inst 2007 Jun 20;99(12):962-72. Epub 2007 Jun 12 doi: 10.1093/jnci/djm010. PMID: 17565153
Epidemiology of AIDS-related tumours in developed and developing countries.
Dal Maso L, Serraino D, Franceschi S
Eur J Cancer 2001 Jul;37(10):1188-201. doi: 10.1016/s0959-8049(01)00120-4. PMID: 11423251
Acquired immunodeficiency syndrome-associated cancers in Sub-Saharan Africa.
Thomas JO
Semin Oncol 2001 Apr;28(2):198-206. doi: 10.1016/s0093-7754(01)90092-2. PMID: 11301383
Opportunistic infections update.
Proj Inf Perspect 1998 Apr;(24):17-9. PMID: 11365715

Recent systematic reviews

Assessing the impact of HAART on the incidence of defining and non-defining AIDS cancers among patients with HIV/AIDS: a systematic review.
Cobucci RN, Lima PH, de Souza PC, Costa VV, Cornetta Mda C, Fernandes JV, Gonçalves AK
J Infect Public Health 2015 Jan-Feb;8(1):1-10. Epub 2014 Oct 5 doi: 10.1016/j.jiph.2014.08.003. PMID: 25294086

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