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Cervical adenoid cystic carcinoma

MedGen UID:
232337
Concept ID:
C1332911
Neoplastic Process
Synonym: Adenoid cystic carcinoma of the cervix uteri
SNOMED CT: Adenoid cystic carcinoma of cervix uteri (763064007); Cervical adenoid cystic carcinoma (763064007)
 
Monarch Initiative: MONDO:0006133
Orphanet: ORPHA213823

Definition

A rare, highly aggressive uterine cancer, macroscopically appearing as an irregular, slow-growing, non-friable, polypoid mass on the uterine cervix and histologically showing a pseudoglandular or cribriform growth pattern. It presents with vaginal bleeding and discharge and abdominal or pelvic pain. The tumor is highly infiltrative, often associated with vascular, lymphatic and perineural invasion, with subsequent haematogenous spread and early recurrence. [from ORDO]

Professional guidelines

PubMed

Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR Jr, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meço C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M Jr, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN
Int Forum Allergy Rhinol 2024 Feb;14(2):149-608. Epub 2024 Jan 2 doi: 10.1002/alr.23262. PMID: 37658764
Fang Y, Peng Z, Wang Y, Gao K, Liu Y, Fan R, Zhang H, Xie Z, Jiang W
Oral Oncol 2022 Jul;130:105945. Epub 2022 Jun 2 doi: 10.1016/j.oraloncology.2022.105945. PMID: 35662026
Cantù G
Acta Otorhinolaryngol Ital 2021 Aug;41(4):296-307. doi: 10.14639/0392-100X-N1729. PMID: 34533533Free PMC Article

Recent clinical studies

Etiology

Chen TD, Chuang HC, Lee LY
Int J Gynecol Pathol 2012 Jan;31(1):25-32. doi: 10.1097/PGP.0b013e31822103a1. PMID: 22123720

Diagnosis

Chen TD, Chuang HC, Lee LY
Int J Gynecol Pathol 2012 Jan;31(1):25-32. doi: 10.1097/PGP.0b013e31822103a1. PMID: 22123720
Morimura Y, Honda T, Hoshi K, Yamada J, Nemoto K, Sato A
Obstet Gynecol 1995 May;85(5 Pt 2):903-5. doi: 10.1016/0029-7844(94)00406-4. PMID: 7724157
Dayton V, Henry M, Stanley MW, Carson L, Taber E
Acta Cytol 1990 Mar-Apr;34(2):125-8. PMID: 2157320
Mazur MT, Battifora HA
Am J Clin Pathol 1982 Apr;77(4):494-500. doi: 10.1093/ajcp/77.4.494. PMID: 6176118

Prognosis

Moosavi MS, Elham Y
Pathol Oncol Res 2020 Apr;26(2):615-625. Epub 2019 Mar 29 doi: 10.1007/s12253-019-00646-9. PMID: 30927206
Chen TD, Chuang HC, Lee LY
Int J Gynecol Pathol 2012 Jan;31(1):25-32. doi: 10.1097/PGP.0b013e31822103a1. PMID: 22123720

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