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Choroid epithelioid cell melanoma

MedGen UID:
232360
•Concept ID:
C1333024
•
Neoplastic Process
Synonyms: Choroid Epithelioid Cell Melanoma; choroid epithelioid cell melanoma; Choroidal Epithelioid Cell Melanoma; choroidal epithelioid cell melanoma; Epithelioid Cell Melanoma of Choroid; epithelioid cell melanoma of choroid; epithelioid cell melanoma of optic choroid; Epithelioid Cell Melanoma of the Choroid; epithelioid cell melanoma of the choroid; optic choroid epithelioid cell melanoma
 
Monarch Initiative: MONDO:0004085

Definition

A choroid melanoma characterized by the presence of malignant large epithelioid melanocytes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChoroid epithelioid cell melanoma

Professional guidelines

PubMed

Characterization, treatment, and outcome of uveal melanoma in the first two years of life.
Yousef YA, Alkilany M
Hematol Oncol Stem Cell Ther 2015 Mar;8(1):1-5. Epub 2014 Oct 6 doi: 10.1016/j.hemonc.2014.09.004. PMID: 25300563
Update on the management of posterior uveal melanoma.
Zhao DY, Shields CL, Shields JA, Gunduz K
J Ophthalmic Nurs Technol 1998 Mar-Apr;17(2):66-71. PMID: 9677975

Recent clinical studies

Etiology

Diagnostic Cytologic Features of Uveal Melanoma.
Medina CA, Biscotti CV, Singh N, Singh AD
Ophthalmology 2015 Aug;122(8):1580-4. Epub 2015 May 23 doi: 10.1016/j.ophtha.2015.04.013. PMID: 26012864
Epidemiological trends in uveal melanoma.
Andreoli MT, Mieler WF, Leiderman YI
Br J Ophthalmol 2015 Nov;99(11):1550-3. Epub 2015 Apr 22 doi: 10.1136/bjophthalmol-2015-306810. PMID: 25904122
Characterization, treatment, and outcome of uveal melanoma in the first two years of life.
Yousef YA, Alkilany M
Hematol Oncol Stem Cell Ther 2015 Mar;8(1):1-5. Epub 2014 Oct 6 doi: 10.1016/j.hemonc.2014.09.004. PMID: 25300563
The pathology of ocular cancer.
Eagle RC Jr
Eye (Lond) 2013 Feb;27(2):128-36. Epub 2012 Nov 16 doi: 10.1038/eye.2012.237. PMID: 23154492Free PMC Article
Eye-wall resection.
Char DH, Miller T, Crawford JB
Trans Am Ophthalmol Soc 2000;98:153-9; discussion 159-61. PMID: 11190019Free PMC Article

Diagnosis

VITREOUS SEEDING OF CHOROIDAL MELANOMA.
Raval V, Bowen RC, Soto H, Biscotti C, Yeaney G, Sears J, Singh A
Retina 2021 Apr 1;41(4):890-894. doi: 10.1097/IAE.0000000000002989. PMID: 33009220
Primary lesions that may imitate metastatic tumors histologically: A selective review.
Wick MR
Semin Diagn Pathol 2018 Mar;35(2):123-142. Epub 2017 Nov 17 doi: 10.1053/j.semdp.2017.11.010. PMID: 29174934
Epidemiological trends in uveal melanoma.
Andreoli MT, Mieler WF, Leiderman YI
Br J Ophthalmol 2015 Nov;99(11):1550-3. Epub 2015 Apr 22 doi: 10.1136/bjophthalmol-2015-306810. PMID: 25904122
Uveal melanoma: estimating prognosis.
Kaliki S, Shields CL, Shields JA
Indian J Ophthalmol 2015 Feb;63(2):93-102. doi: 10.4103/0301-4738.154367. PMID: 25827538Free PMC Article
Characterization, treatment, and outcome of uveal melanoma in the first two years of life.
Yousef YA, Alkilany M
Hematol Oncol Stem Cell Ther 2015 Mar;8(1):1-5. Epub 2014 Oct 6 doi: 10.1016/j.hemonc.2014.09.004. PMID: 25300563

Therapy

No differences in the long-term prognosis of iris and choroidal melanomas when adjusting for tumor thickness and diameter.
Sabazade S, Herrspiegel C, Gill V, Stålhammar G
BMC Cancer 2021 Nov 24;21(1):1270. doi: 10.1186/s12885-021-09002-0. PMID: 34819035Free PMC Article
VITREOUS SEEDING OF CHOROIDAL MELANOMA.
Raval V, Bowen RC, Soto H, Biscotti C, Yeaney G, Sears J, Singh A
Retina 2021 Apr 1;41(4):890-894. doi: 10.1097/IAE.0000000000002989. PMID: 33009220
Neovascular glaucoma after stereotactic radiotherapy for juxtapapillary choroidal melanoma: histopathologic and dosimetric findings.
Fernandes BF, Weisbrod D, Yücel YH, Follwell M, Krema H, Heydarian M, Xu W, Payne D, McGowan H, Simpson ER, Laperriere N, Sahgal A
Int J Radiat Oncol Biol Phys 2011 Jun 1;80(2):377-84. Epub 2010 Sep 23 doi: 10.1016/j.ijrobp.2010.04.073. PMID: 20864264
Choroidal melanomas in Hispanic patients.
Hudson HL, Valluri S, Rao NA
Am J Ophthalmol 1994 Jul 15;118(1):57-62. doi: 10.1016/s0002-9394(14)72842-9. PMID: 8023876
Heterotransplantation of human uveal melanoma.
Liggett PE, Lo G, Pince KJ, Rao NA, Pascal SG, Kan-Mitchel J
Graefes Arch Clin Exp Ophthalmol 1993;231(1):15-20. doi: 10.1007/BF01681695. PMID: 8428676

Prognosis

Epidemiological trends in uveal melanoma.
Andreoli MT, Mieler WF, Leiderman YI
Br J Ophthalmol 2015 Nov;99(11):1550-3. Epub 2015 Apr 22 doi: 10.1136/bjophthalmol-2015-306810. PMID: 25904122
Uveal melanoma: estimating prognosis.
Kaliki S, Shields CL, Shields JA
Indian J Ophthalmol 2015 Feb;63(2):93-102. doi: 10.4103/0301-4738.154367. PMID: 25827538Free PMC Article
Characterization, treatment, and outcome of uveal melanoma in the first two years of life.
Yousef YA, Alkilany M
Hematol Oncol Stem Cell Ther 2015 Mar;8(1):1-5. Epub 2014 Oct 6 doi: 10.1016/j.hemonc.2014.09.004. PMID: 25300563
The pathology of ocular cancer.
Eagle RC Jr
Eye (Lond) 2013 Feb;27(2):128-36. Epub 2012 Nov 16 doi: 10.1038/eye.2012.237. PMID: 23154492Free PMC Article
Pathology of ocular melanomas.
McCartney AC
Br Med Bull 1995 Jul;51(3):678-93. doi: 10.1093/oxfordjournals.bmb.a072986. PMID: 7552088

Clinical prediction guides

Expression of Cell Cycle Markers and Proliferation Factors during Human Eye Embryogenesis and Tumorigenesis.
Marin Lovrić J, Filipović N, Znaor L, Rančić A, Petričević J, Kunac N, Šoljić V, Saraga-Babić M, Vukojević K
Int J Mol Sci 2022 Aug 20;23(16) doi: 10.3390/ijms23169421. PMID: 36012688Free PMC Article
VITREOUS SEEDING OF CHOROIDAL MELANOMA.
Raval V, Bowen RC, Soto H, Biscotti C, Yeaney G, Sears J, Singh A
Retina 2021 Apr 1;41(4):890-894. doi: 10.1097/IAE.0000000000002989. PMID: 33009220
Primary lesions that may imitate metastatic tumors histologically: A selective review.
Wick MR
Semin Diagn Pathol 2018 Mar;35(2):123-142. Epub 2017 Nov 17 doi: 10.1053/j.semdp.2017.11.010. PMID: 29174934
Epidemiological trends in uveal melanoma.
Andreoli MT, Mieler WF, Leiderman YI
Br J Ophthalmol 2015 Nov;99(11):1550-3. Epub 2015 Apr 22 doi: 10.1136/bjophthalmol-2015-306810. PMID: 25904122
Uveal melanoma: estimating prognosis.
Kaliki S, Shields CL, Shields JA
Indian J Ophthalmol 2015 Feb;63(2):93-102. doi: 10.4103/0301-4738.154367. PMID: 25827538Free PMC Article

Recent systematic reviews

Characterization, treatment, and outcome of uveal melanoma in the first two years of life.
Yousef YA, Alkilany M
Hematol Oncol Stem Cell Ther 2015 Mar;8(1):1-5. Epub 2014 Oct 6 doi: 10.1016/j.hemonc.2014.09.004. PMID: 25300563

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