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Conventional fibrosarcoma

MedGen UID:
232393
•Concept ID:
C1333156
•
Neoplastic Process
Synonyms: Classic Fibrosarcoma; classic fibrosarcoma; Classical Fibrosarcoma; classical fibrosarcoma; Conventional Fibrosarcoma; conventional fibrosarcoma
 
Monarch Initiative: MONDO:0002677

Definition

A malignant mesenchymal neoplasm composed of fibroblasts, and characterized by collagen production and usually a herringbone architectural pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVConventional fibrosarcoma

Professional guidelines

PubMed

Biology and Management of High-Grade Chondrosarcoma: An Update on Targets and Treatment Options.
Tlemsani C, Larousserie F, De Percin S, Audard V, Hadjadj D, Chen J, Biau D, Anract P, Terris B, Goldwasser F, Pasmant E, Boudou-Rouquette P
Int J Mol Sci 2023 Jan 10;24(2) doi: 10.3390/ijms24021361. PMID: 36674874Free PMC Article
Low-grade Fibromyxoid Sarcoma: Treatment Outcomes and Efficacy of Chemotherapy.
Chamberlain F, Engelmann B, Al-Muderis O, Messiou C, Thway K, Miah A, Zaidi S, Constantinidou A, Benson C, Gennatas S, Jones RL
In Vivo 2020 Jan-Feb;34(1):239-245. doi: 10.21873/invivo.11766. PMID: 31882484Free PMC Article
Resveratrol in management of bone and spinal cancers.
Chen G, Xia H, Zhang ZG, Yu HL
Nat Prod Res 2019 Feb;33(4):516-526. Epub 2017 Oct 20 doi: 10.1080/14786419.2017.1389936. PMID: 29052449

Recent clinical studies

Etiology

The contribution of electron microscopy to the characterization of soft tissue fibrosarcomas.
Franchi A, Santucci M
Ultrastruct Pathol 2013 Feb;37(1):9-14. doi: 10.3109/01913123.2012.670017. PMID: 23383612
Ultrastructure of cellular congenital mesoblastic nephroma.
O'Malley DP, Mierau GW, Beckwith JB, Weeks DA
Ultrastruct Pathol 1996 Sep-Oct;20(5):417-27. doi: 10.3109/01913129609016344. PMID: 8883325
Sclerosing epithelioid fibrosarcoma. A variant of fibrosarcoma simulating carcinoma.
Meis-Kindblom JM, Kindblom LG, Enzinger FM
Am J Surg Pathol 1995 Sep;19(9):979-93. doi: 10.1097/00000478-199509000-00001. PMID: 7661286

Diagnosis

The contribution of electron microscopy to the characterization of soft tissue fibrosarcomas.
Franchi A, Santucci M
Ultrastruct Pathol 2013 Feb;37(1):9-14. doi: 10.3109/01913123.2012.670017. PMID: 23383612
Ultrastructure of cellular congenital mesoblastic nephroma.
O'Malley DP, Mierau GW, Beckwith JB, Weeks DA
Ultrastruct Pathol 1996 Sep-Oct;20(5):417-27. doi: 10.3109/01913129609016344. PMID: 8883325
Sclerosing epithelioid fibrosarcoma. A variant of fibrosarcoma simulating carcinoma.
Meis-Kindblom JM, Kindblom LG, Enzinger FM
Am J Surg Pathol 1995 Sep;19(9):979-93. doi: 10.1097/00000478-199509000-00001. PMID: 7661286
Value of S-100 protein in the diagnosis of soft tissue tumors with particular reference to benign and malignant Schwann cell tumors.
Weiss SW, Langloss JM, Enzinger FM
Lab Invest 1983 Sep;49(3):299-308. PMID: 6310227

Prognosis

The contribution of electron microscopy to the characterization of soft tissue fibrosarcomas.
Franchi A, Santucci M
Ultrastruct Pathol 2013 Feb;37(1):9-14. doi: 10.3109/01913123.2012.670017. PMID: 23383612
Low-grade abdominopelvic sarcoma with myofibroblastic features (low-grade myofibroblastic sarcoma): clinicopathological, immunohistochemical, molecular genetic and ultrastructural study of two cases with literature review.
Agaimy A, Wünsch PH, Schroeder J, Gaumann A, Dietmaier W, Hartmann A, Hofstaedter F, Mentzel T
J Clin Pathol 2008 Mar;61(3):301-6. Epub 2007 May 18 doi: 10.1136/jcp.2007.048561. PMID: 17513510
Sclerosing epithelioid fibrosarcoma. A variant of fibrosarcoma simulating carcinoma.
Meis-Kindblom JM, Kindblom LG, Enzinger FM
Am J Surg Pathol 1995 Sep;19(9):979-93. doi: 10.1097/00000478-199509000-00001. PMID: 7661286

Clinical prediction guides

The contribution of electron microscopy to the characterization of soft tissue fibrosarcomas.
Franchi A, Santucci M
Ultrastruct Pathol 2013 Feb;37(1):9-14. doi: 10.3109/01913123.2012.670017. PMID: 23383612
Ultrastructure of cellular congenital mesoblastic nephroma.
O'Malley DP, Mierau GW, Beckwith JB, Weeks DA
Ultrastruct Pathol 1996 Sep-Oct;20(5):417-27. doi: 10.3109/01913129609016344. PMID: 8883325

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