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Bone cancer

MedGen UID:
79002
Concept ID:
C0279530
Neoplastic Process
Synonyms: Bone Cancer; Cancer of Bone; Cancer of the Bone
SNOMED CT: Malignant neoplasm of bone (428281000)
 
Monarch Initiative: MONDO:0002129

Definition

A primary or metastatic malignant neoplasm affecting the bone or articular cartilage. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBone cancer

Professional guidelines

PubMed

Tsukamoto S, Kido A, Tanaka Y, Facchini G, Peta G, Rossi G, Mavrogenis AF
Curr Oncol 2021 Aug 29;28(5):3347-3372. doi: 10.3390/curroncol28050290. PMID: 34590591Free PMC Article
Jafari F, Javdansirat S, Sanaie S, Naseri A, Shamekh A, Rostamzadeh D, Dolati S
Ann Diagn Pathol 2020 Dec;49:151654. Epub 2020 Oct 25 doi: 10.1016/j.anndiagpath.2020.151654. PMID: 33130384
Ferguson JL, Turner SP
Am Fam Physician 2018 Aug 15;98(4):205-213. PMID: 30215968

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Bone Cancer, 2024

Recent clinical studies

Etiology

Naseri A, Sanaie S, Hamzehzadeh S, Seyedi-Sahebari S, Hosseini MS, Gholipour-Khalili E, Rezazadeh-Gavgani E, Majidazar R, Seraji P, Daneshvar S, Rezazadeh-Gavgani E
J Basic Clin Physiol Pharmacol 2023 Mar 1;34(2):151-160. Epub 2022 Dec 7 doi: 10.1515/jbcpp-2022-0252. PMID: 36474458
Cole S, Gianferante DM, Zhu B, Mirabello L
Cancer 2022 Jun 1;128(11):2107-2118. Epub 2022 Feb 28 doi: 10.1002/cncr.34163. PMID: 35226758
Suh E, Stratton KL, Leisenring WM, Nathan PC, Ford JS, Freyer DR, McNeer JL, Stock W, Stovall M, Krull KR, Sklar CA, Neglia JP, Armstrong GT, Oeffinger KC, Robison LL, Henderson TO
Lancet Oncol 2020 Mar;21(3):421-435. Epub 2020 Feb 14 doi: 10.1016/S1470-2045(19)30800-9. PMID: 32066543Free PMC Article
Imran M, Salehi B, Sharifi-Rad J, Aslam Gondal T, Saeed F, Imran A, Shahbaz M, Tsouh Fokou PV, Umair Arshad M, Khan H, Guerreiro SG, Martins N, Estevinho LM
Molecules 2019 Jun 19;24(12) doi: 10.3390/molecules24122277. PMID: 31248102Free PMC Article
Pazianas M, Abrahamsen B
Bone 2011 Jul;49(1):103-10. Epub 2011 Jan 12 doi: 10.1016/j.bone.2011.01.003. PMID: 21236370

Diagnosis

Gamret AC, Klingbeil KD, Fertig RM, Jahan-Tigh RR, Silapunt S, Uzoma M, Gaudi S, Romanelli P
Skinmed 2020;18(6):382-384. Epub 2020 Dec 1 PMID: 33397571
Jafari F, Javdansirat S, Sanaie S, Naseri A, Shamekh A, Rostamzadeh D, Dolati S
Ann Diagn Pathol 2020 Dec;49:151654. Epub 2020 Oct 25 doi: 10.1016/j.anndiagpath.2020.151654. PMID: 33130384
Am Fam Physician 2018 Aug 15;98(4):Online. PMID: 30215985
Ferguson JL, Turner SP
Am Fam Physician 2018 Aug 15;98(4):205-213. PMID: 30215968
Biermann JS, Adkins DR, Agulnik M, Benjamin RS, Brigman B, Butrynski JE, Cheong D, Chow W, Curry WT, Frassica DA, Frassica FJ, Hande KR, Hornicek FJ, Jones RL, Mayerson J, McGarry SV, McGrath B, Morris CD, O'Donnell RJ, Randall RL, Santana VM, Satcher RL, Siegel HJ, von Mehren M, Bergman MA, Sundar H; National complrehensive cancer network
J Natl Compr Canc Netw 2013 Jun 1;11(6):688-723. doi: 10.6004/jnccn.2013.0088. PMID: 23744868

Therapy

Gounder M, Ratan R, Alcindor T, Schöffski P, van der Graaf WT, Wilky BA, Riedel RF, Lim A, Smith LM, Moody S, Attia S, Chawla S, D'Amato G, Federman N, Merriam P, Van Tine BA, Vincenzi B, Benson C, Bui NQ, Chugh R, Tinoco G, Charlson J, Dileo P, Hartner L, Lapeire L, Mazzeo F, Palmerini E, Reichardt P, Stacchiotti S, Bailey HH, Burgess MA, Cote GM, Davis LE, Deshpande H, Gelderblom H, Grignani G, Loggers E, Philip T, Pressey JG, Kummar S, Kasper B
N Engl J Med 2023 Mar 9;388(10):898-912. doi: 10.1056/NEJMoa2210140. PMID: 36884323Free PMC Article
Naseri A, Sanaie S, Hamzehzadeh S, Seyedi-Sahebari S, Hosseini MS, Gholipour-Khalili E, Rezazadeh-Gavgani E, Majidazar R, Seraji P, Daneshvar S, Rezazadeh-Gavgani E
J Basic Clin Physiol Pharmacol 2023 Mar 1;34(2):151-160. Epub 2022 Dec 7 doi: 10.1515/jbcpp-2022-0252. PMID: 36474458
Lv Z, Guo Y
Front Endocrinol (Lausanne) 2020;11:191. Epub 2020 Apr 16 doi: 10.3389/fendo.2020.00191. PMID: 32425881Free PMC Article
Lucchesi M, Lanzetta G, Antonuzzo A, Rozzi A, Sardi I, Favre C, Ripamonti CI, Santini D, Armento G
Crit Rev Oncol Hematol 2017 Nov;119:66-74. Epub 2017 Aug 25 doi: 10.1016/j.critrevonc.2017.08.005. PMID: 28893462
Brown HK, Tellez-Gabriel M, Heymann D
Cancer Lett 2017 Feb 1;386:189-195. Epub 2016 Nov 25 doi: 10.1016/j.canlet.2016.11.019. PMID: 27894960

Prognosis

Cole S, Gianferante DM, Zhu B, Mirabello L
Cancer 2022 Jun 1;128(11):2107-2118. Epub 2022 Feb 28 doi: 10.1002/cncr.34163. PMID: 35226758
Chen B, Zeng Y, Liu B, Lu G, Xiang Z, Chen J, Yu Y, Zuo Z, Lin Y, Ma J
Front Endocrinol (Lausanne) 2021;12:672024. Epub 2021 Jul 30 doi: 10.3389/fendo.2021.672024. PMID: 34393996Free PMC Article
Suh E, Stratton KL, Leisenring WM, Nathan PC, Ford JS, Freyer DR, McNeer JL, Stock W, Stovall M, Krull KR, Sklar CA, Neglia JP, Armstrong GT, Oeffinger KC, Robison LL, Henderson TO
Lancet Oncol 2020 Mar;21(3):421-435. Epub 2020 Feb 14 doi: 10.1016/S1470-2045(19)30800-9. PMID: 32066543Free PMC Article
Ferguson JL, Turner SP
Am Fam Physician 2018 Aug 15;98(4):205-213. PMID: 30215968
Brown HK, Tellez-Gabriel M, Heymann D
Cancer Lett 2017 Feb 1;386:189-195. Epub 2016 Nov 25 doi: 10.1016/j.canlet.2016.11.019. PMID: 27894960

Clinical prediction guides

Gounder M, Ratan R, Alcindor T, Schöffski P, van der Graaf WT, Wilky BA, Riedel RF, Lim A, Smith LM, Moody S, Attia S, Chawla S, D'Amato G, Federman N, Merriam P, Van Tine BA, Vincenzi B, Benson C, Bui NQ, Chugh R, Tinoco G, Charlson J, Dileo P, Hartner L, Lapeire L, Mazzeo F, Palmerini E, Reichardt P, Stacchiotti S, Bailey HH, Burgess MA, Cote GM, Davis LE, Deshpande H, Gelderblom H, Grignani G, Loggers E, Philip T, Pressey JG, Kummar S, Kasper B
N Engl J Med 2023 Mar 9;388(10):898-912. doi: 10.1056/NEJMoa2210140. PMID: 36884323Free PMC Article
Naseri A, Sanaie S, Hamzehzadeh S, Seyedi-Sahebari S, Hosseini MS, Gholipour-Khalili E, Rezazadeh-Gavgani E, Majidazar R, Seraji P, Daneshvar S, Rezazadeh-Gavgani E
J Basic Clin Physiol Pharmacol 2023 Mar 1;34(2):151-160. Epub 2022 Dec 7 doi: 10.1515/jbcpp-2022-0252. PMID: 36474458
Cole S, Gianferante DM, Zhu B, Mirabello L
Cancer 2022 Jun 1;128(11):2107-2118. Epub 2022 Feb 28 doi: 10.1002/cncr.34163. PMID: 35226758
Chen B, Zeng Y, Liu B, Lu G, Xiang Z, Chen J, Yu Y, Zuo Z, Lin Y, Ma J
Front Endocrinol (Lausanne) 2021;12:672024. Epub 2021 Jul 30 doi: 10.3389/fendo.2021.672024. PMID: 34393996Free PMC Article
Nugent M
Adv Exp Med Biol 2015;889:201-30. doi: 10.1007/978-3-319-23730-5_11. PMID: 26659003

Recent systematic reviews

Hajduga N, Subramanian MP, Brown H, McNally R, Zohoori V, Rand V
Bone 2025 Jan;190:117320. Epub 2024 Nov 5 doi: 10.1016/j.bone.2024.117320. PMID: 39510434
Busnelli A, Vitagliano A, Mensi L, Acerboni S, Bulfoni A, Filippi F, Somigliana E
Reprod Biomed Online 2020 Jul;41(1):96-112. Epub 2020 Feb 22 doi: 10.1016/j.rbmo.2020.02.008. PMID: 32456969
Fernandes RS, Dos Santos Ferreira D, de Aguiar Ferreira C, Giammarile F, Rubello D, de Barros ALB
Biomed Pharmacother 2016 Oct;83:1253-1264. Epub 2016 Aug 24 doi: 10.1016/j.biopha.2016.08.039. PMID: 27565848
Kwong TN, Furtado S, Gerrand C
Eur J Surg Oncol 2014 Sep;40(9):1109-24. Epub 2014 Apr 4 doi: 10.1016/j.ejso.2014.03.015. PMID: 24767804
Finlay IG, Mason MD, Shelley M
Lancet Oncol 2005 Jun;6(6):392-400. doi: 10.1016/S1470-2045(05)70206-0. PMID: 15925817

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
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    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Bone Cancer, 2024

    Consumer resources

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