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Gastric cardia adenocarcinoma

MedGen UID:
232543
•Concept ID:
C1333762
•
Neoplastic Process
Synonyms: Adenocarcinoma of Cardia of Stomach; adenocarcinoma of cardia of stomach; Adenocarcinoma of Gastric Cardia; adenocarcinoma of gastric cardia; Adenocarcinoma of the Cardia of the Stomach; adenocarcinoma of the cardia of the stomach; Adenocarcinoma of the Gastric Cardia; adenocarcinoma of the gastric cardia; cardia of stomach adenocarcinoma; Gastric Cardia Adenocarcinoma; gastric cardia adenocarcinoma
 
Monarch Initiative: MONDO:0003835

Definition

An adenocarcinoma that arises from the gastric cardia. The majority of cases have been reclassified as gastroesophageal junction adenocarcinomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastric cardia adenocarcinoma

Professional guidelines

PubMed

Helicobacter pylori eradication treatment and the risk of gastric adenocarcinoma in a Western population.
Doorakkers E, Lagergren J, Engstrand L, Brusselaers N
Gut 2018 Dec;67(12):2092-2096. Epub 2018 Jan 30 doi: 10.1136/gutjnl-2017-315363. PMID: 29382776
Treatment and survival in a population-based sample of patients diagnosed with gastroesophageal adenocarcinoma.
Cronin-Fenton DP, Mooney MM, Clegg LX, Harlan LC
World J Gastroenterol 2008 May 28;14(20):3165-73. doi: 10.3748/wjg.14.3165. PMID: 18506920Free PMC Article
Asia-Pacific consensus guidelines on gastric cancer prevention.
Fock KM, Talley N, Moayyedi P, Hunt R, Azuma T, Sugano K, Xiao SD, Lam SK, Goh KL, Chiba T, Uemura N, Kim JG, Kim N, Ang TL, Mahachai V, Mitchell H, Rani AA, Liou JM, Vilaichone RK, Sollano J; Asia-Pacific Gastric Cancer Consensus Conference
J Gastroenterol Hepatol 2008 Mar;23(3):351-65. doi: 10.1111/j.1440-1746.2008.05314.x. PMID: 18318820

Recent clinical studies

Etiology

Red and processed meat consumption and gastric cancer risk: a systematic review and meta-analysis.
Zhao Z, Yin Z, Zhao Q
Oncotarget 2017 May 2;8(18):30563-30575. doi: 10.18632/oncotarget.15699. PMID: 28430644Free PMC Article
Obesity and related risk factors in gastric cardia adenocarcinoma.
Olefson S, Moss SF
Gastric Cancer 2015 Jan;18(1):23-32. Epub 2014 Sep 11 doi: 10.1007/s10120-014-0425-4. PMID: 25209115
A meta-analysis on alcohol drinking and esophageal and gastric cardia adenocarcinoma risk.
Tramacere I, Pelucchi C, Bagnardi V, Rota M, Scotti L, Islami F, Corrao G, Boffetta P, La Vecchia C, Negri E
Ann Oncol 2012 Feb;23(2):287-97. Epub 2011 May 5 doi: 10.1093/annonc/mdr136. PMID: 21551004
Tobacco smoking and esophageal and gastric cardia adenocarcinoma: a meta-analysis.
Tramacere I, La Vecchia C, Negri E
Epidemiology 2011 May;22(3):344-9. doi: 10.1097/EDE.0b013e31821092cd. PMID: 21330928
Gastric atrophy and risk of oesophageal cancer and gastric cardia adenocarcinoma--a systematic review and meta-analysis.
Islami F, Sheikhattari P, Ren JS, Kamangar F
Ann Oncol 2011 Apr;22(4):754-760. Epub 2010 Sep 22 doi: 10.1093/annonc/mdq411. PMID: 20860989

Diagnosis

Expression of MiR-129 in Patients with Gastric Cardia Adenocarcinoma and Prognostic Analysis.
Yang J
Clin Lab 2022 Jan 1;68(1) doi: 10.7754/Clin.Lab.2021.210338. PMID: 35023689
Abdominal obesity and gastroesophageal cancer risk: systematic review and meta-analysis of prospective studies.
Du X, Hidayat K, Shi BM
Biosci Rep 2017 Jun 30;37(3) Epub 2017 May 11 doi: 10.1042/BSR20160474. PMID: 28336766Free PMC Article
Metabolic syndrome and esophageal and gastric cancer.
Lin Y, Ness-Jensen E, Hveem K, Lagergren J, Lu Y
Cancer Causes Control 2015 Dec;26(12):1825-34. Epub 2015 Oct 8 doi: 10.1007/s10552-015-0675-4. PMID: 26450604
Clinicopathological features and prognosis of gastric cardia adenocarcinoma: a multi-institutional US study.
Amini N, Spolverato G, Kim Y, Squires MH, Poultsides GA, Fields R, Schmidt C, Weber SM, Votanopoulos K, Maithel SK, Pawlik TM
J Surg Oncol 2015 Mar;111(3):285-92. Epub 2014 Oct 10 doi: 10.1002/jso.23799. PMID: 25308915
Body mass index and adenocarcinomas of the esophagus or gastric cardia: a systematic review and meta-analysis.
Kubo A, Corley DA
Cancer Epidemiol Biomarkers Prev 2006 May;15(5):872-8. doi: 10.1158/1055-9965.EPI-05-0860. PMID: 16702363

Therapy

Red and processed meat consumption and gastric cancer risk: a systematic review and meta-analysis.
Zhao Z, Yin Z, Zhao Q
Oncotarget 2017 May 2;8(18):30563-30575. doi: 10.18632/oncotarget.15699. PMID: 28430644Free PMC Article
Abdominal obesity and gastroesophageal cancer risk: systematic review and meta-analysis of prospective studies.
Du X, Hidayat K, Shi BM
Biosci Rep 2017 Jun 30;37(3) Epub 2017 May 11 doi: 10.1042/BSR20160474. PMID: 28336766Free PMC Article
A meta-analysis on alcohol drinking and esophageal and gastric cardia adenocarcinoma risk.
Tramacere I, Pelucchi C, Bagnardi V, Rota M, Scotti L, Islami F, Corrao G, Boffetta P, La Vecchia C, Negri E
Ann Oncol 2012 Feb;23(2):287-97. Epub 2011 May 5 doi: 10.1093/annonc/mdr136. PMID: 21551004
Tobacco smoking and esophageal and gastric cardia adenocarcinoma: a meta-analysis.
Tramacere I, La Vecchia C, Negri E
Epidemiology 2011 May;22(3):344-9. doi: 10.1097/EDE.0b013e31821092cd. PMID: 21330928
Gastric atrophy and risk of oesophageal cancer and gastric cardia adenocarcinoma--a systematic review and meta-analysis.
Islami F, Sheikhattari P, Ren JS, Kamangar F
Ann Oncol 2011 Apr;22(4):754-760. Epub 2010 Sep 22 doi: 10.1093/annonc/mdq411. PMID: 20860989

Prognosis

Expression of MiR-129 in Patients with Gastric Cardia Adenocarcinoma and Prognostic Analysis.
Yang J
Clin Lab 2022 Jan 1;68(1) doi: 10.7754/Clin.Lab.2021.210338. PMID: 35023689
Long Non-coding RNA LINC01503 Promotes Gastric Cardia Adenocarcinoma Progression via miR-133a-5p/VIM Axis and EMT Process.
Guo Y, Sun P, Guo W, Dong Z
Dig Dis Sci 2021 Oct;66(10):3391-3403. Epub 2020 Nov 17 doi: 10.1007/s10620-020-06690-9. PMID: 33200343
MiR-638 regulates gastric cardia adenocarcinoma cell proliferation, apoptosis, migration and invasion by targeting MACC1.
Wei CJ, Zhang ZW, Lu JH, Mao YM
Neoplasma 2020 May;67(3):537-546. Epub 2020 Feb 17 doi: 10.4149/neo_2020_190719N651. PMID: 32064885
Clinicopathological features and prognosis of gastric cardia adenocarcinoma: a multi-institutional US study.
Amini N, Spolverato G, Kim Y, Squires MH, Poultsides GA, Fields R, Schmidt C, Weber SM, Votanopoulos K, Maithel SK, Pawlik TM
J Surg Oncol 2015 Mar;111(3):285-92. Epub 2014 Oct 10 doi: 10.1002/jso.23799. PMID: 25308915
Tobacco smoking and esophageal and gastric cardia adenocarcinoma: a meta-analysis.
Tramacere I, La Vecchia C, Negri E
Epidemiology 2011 May;22(3):344-9. doi: 10.1097/EDE.0b013e31821092cd. PMID: 21330928

Clinical prediction guides

ABO genotypes and the risk of esophageal and gastric cancers.
Chen Y, Hu N, Liao L, Yu K, Shu XO, Zheng W, Yuan JM, Koh WP, Qiao YL, Fan JH, Dawsey SM, Freedman ND, Taylor PR, Goldstein AM, Abnet CC
BMC Cancer 2021 May 22;21(1):589. doi: 10.1186/s12885-021-08334-1. PMID: 34022824Free PMC Article
Metabolic syndrome and esophageal and gastric cancer.
Lin Y, Ness-Jensen E, Hveem K, Lagergren J, Lu Y
Cancer Causes Control 2015 Dec;26(12):1825-34. Epub 2015 Oct 8 doi: 10.1007/s10552-015-0675-4. PMID: 26450604
Esophageal Squamous Cell Carcinoma and Gastric Cardia Adenocarcinoma Shared Susceptibility Locus in C20orf54: Evidence from Published Studies.
Duan F, Cui S, Song C, Zhao X, Dai L, Shen Y
Sci Rep 2015 Jul 8;5:11961. doi: 10.1038/srep11961. PMID: 26154995Free PMC Article
Body mass index and adenocarcinomas of the esophagus or gastric cardia: a systematic review and meta-analysis.
Kubo A, Corley DA
Cancer Epidemiol Biomarkers Prev 2006 May;15(5):872-8. doi: 10.1158/1055-9965.EPI-05-0860. PMID: 16702363
Epidemiological and clinical aspects of nonsteroidal anti-inflammatory drugs and cancer risks.
Moran EM
J Environ Pathol Toxicol Oncol 2002;21(2):193-201. PMID: 12086406

Recent systematic reviews

Red and processed meat consumption and gastric cancer risk: a systematic review and meta-analysis.
Zhao Z, Yin Z, Zhao Q
Oncotarget 2017 May 2;8(18):30563-30575. doi: 10.18632/oncotarget.15699. PMID: 28430644Free PMC Article
Abdominal obesity and gastroesophageal cancer risk: systematic review and meta-analysis of prospective studies.
Du X, Hidayat K, Shi BM
Biosci Rep 2017 Jun 30;37(3) Epub 2017 May 11 doi: 10.1042/BSR20160474. PMID: 28336766Free PMC Article
Esophageal Squamous Cell Carcinoma and Gastric Cardia Adenocarcinoma Shared Susceptibility Locus in C20orf54: Evidence from Published Studies.
Duan F, Cui S, Song C, Zhao X, Dai L, Shen Y
Sci Rep 2015 Jul 8;5:11961. doi: 10.1038/srep11961. PMID: 26154995Free PMC Article
The association between physical activity and gastroesophageal cancer: systematic review and meta-analysis.
Behrens G, Jochem C, Keimling M, Ricci C, Schmid D, Leitzmann MF
Eur J Epidemiol 2014 Mar;29(3):151-70. Epub 2014 Apr 6 doi: 10.1007/s10654-014-9895-2. PMID: 24705782
Gastric atrophy and risk of oesophageal cancer and gastric cardia adenocarcinoma--a systematic review and meta-analysis.
Islami F, Sheikhattari P, Ren JS, Kamangar F
Ann Oncol 2011 Apr;22(4):754-760. Epub 2010 Sep 22 doi: 10.1093/annonc/mdq411. PMID: 20860989

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