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Metachronous osteosarcoma of the bone

MedGen UID:
233695
•Concept ID:
C1334704
•
Neoplastic Process
Synonyms: Metachronous Osteosarcoma; metachronous osteosarcoma; Metachronous Osteosarcoma of the Bone; metachronous osteosarcoma of the bone
 
Monarch Initiative: MONDO:0002632

Definition

A bone osteosarcoma that has metastasized to skeletal or extraskeletal sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetachronous osteosarcoma of the bone

Professional guidelines

PubMed

Treatment of 120 adult osteosarcoma patients with metachronous and synchronous metastases: A retrospective series of the French Sarcoma Group.
Lavit E, Aldea M, Piperno-Neumann S, Firmin N, Italiano A, Isambert N, Kurtz JE, Delcambre C, Lebrun V, Soibinet-Oudot P, Chevreau C, Bompas E, Le Maignan C, Boudou-Rouquette P, Le Cesne A, Mancini J, Blay JY, Duffaud F
Int J Cancer 2022 Feb 15;150(4):645-653. Epub 2021 Oct 5 doi: 10.1002/ijc.33823. PMID: 34562271
Treatment outcome of patients with chondroblastic osteosarcoma of the limbs and pelvis.
Tsagozis P, Laitinen MK, Stevenson JD, Jeys LM, Abudu A, Parry MC
Bone Joint J 2019 Jun;101-B(6):739-744. doi: 10.1302/0301-620X.101B6.BJJ-2018-1090.R1. PMID: 31154835
The role of resection in the treatment of pulmonary metastases from Ewing's sarcoma.
Lanza LA, Miser JS, Pass HI, Roth JA
J Thorac Cardiovasc Surg 1987 Aug;94(2):181-7. PMID: 3613615

Recent clinical studies

Etiology

Treatment outcome of patients with chondroblastic osteosarcoma of the limbs and pelvis.
Tsagozis P, Laitinen MK, Stevenson JD, Jeys LM, Abudu A, Parry MC
Bone Joint J 2019 Jun;101-B(6):739-744. doi: 10.1302/0301-620X.101B6.BJJ-2018-1090.R1. PMID: 31154835
Tumor Syndromes That Include Bone Tumors: An Update.
Gnoli M, Ponti F, Sangiorgi L
Surg Pathol Clin 2017 Sep;10(3):749-764. doi: 10.1016/j.path.2017.04.009. PMID: 28797512
Multicentric osteosarcoma.
Hameed S, Vijayan S, Naik M, Rao S
Singapore Med J 2012 Oct;53(10):e214-7. PMID: 23112033
Osteosarcoma lung metastases detection and principles of multimodal therapy.
Carrle D, Bielack S
Cancer Treat Res 2009;152:165-84. doi: 10.1007/978-1-4419-0284-9_8. PMID: 20213390
Multicentric chondrosarcomas.
Damron TA, Sim FH, Unni KK
Clin Orthop Relat Res 1996 Jul;(328):211-9. doi: 10.1097/00003086-199607000-00033. PMID: 8653959

Diagnosis

CT features of osteosarcoma lung metastasis: a retrospective study of 127 patients.
Silva JAM, Marchiori E, Amorim VB, Barreto MM
J Bras Pneumol 2023;49(2):e20220433. Epub 2023 Apr 28 doi: 10.36416/1806-3756/e20220433. PMID: 37132704Free PMC Article
Treatment outcome of patients with chondroblastic osteosarcoma of the limbs and pelvis.
Tsagozis P, Laitinen MK, Stevenson JD, Jeys LM, Abudu A, Parry MC
Bone Joint J 2019 Jun;101-B(6):739-744. doi: 10.1302/0301-620X.101B6.BJJ-2018-1090.R1. PMID: 31154835
Multicentric osteosarcoma.
Hameed S, Vijayan S, Naik M, Rao S
Singapore Med J 2012 Oct;53(10):e214-7. PMID: 23112033
Osteosarcoma in Paget's disease of bone.
Hansen MF, Seton M, Merchant A
J Bone Miner Res 2006 Dec;21 Suppl 2:P58-63. doi: 10.1359/jbmr.06s211. PMID: 17229010
Multicentric chondrosarcomas.
Damron TA, Sim FH, Unni KK
Clin Orthop Relat Res 1996 Jul;(328):211-9. doi: 10.1097/00003086-199607000-00033. PMID: 8653959

Therapy

Dedifferentiation in low-grade osteosarcoma: a Japanese Musculoskeletal Oncology Group (JMOG) study.
Hirai T, Kobayashi H, Kobayashi E, Saito M, Akiyama T, Kikuta K, Nakai T, Endo M, Tsukamoto S, Hakozaki M, Takenaka S, Nishimura S, Kawashima H, Tanzawa Y, Kawano H, Tanaka S
Int J Clin Oncol 2022 Nov;27(11):1758-1766. Epub 2022 Aug 6 doi: 10.1007/s10147-022-02223-8. PMID: 35932377
Treatment of 120 adult osteosarcoma patients with metachronous and synchronous metastases: A retrospective series of the French Sarcoma Group.
Lavit E, Aldea M, Piperno-Neumann S, Firmin N, Italiano A, Isambert N, Kurtz JE, Delcambre C, Lebrun V, Soibinet-Oudot P, Chevreau C, Bompas E, Le Maignan C, Boudou-Rouquette P, Le Cesne A, Mancini J, Blay JY, Duffaud F
Int J Cancer 2022 Feb 15;150(4):645-653. Epub 2021 Oct 5 doi: 10.1002/ijc.33823. PMID: 34562271
Synchronous and metachronous skeletal osteosarcomas: the Norwegian Radium Hospital experience.
Brandal P, Bjerkehagen B, Bruland OS, Skjeldal S, Bogsrud TV, Hall KS
Acta Oncol 2009;48(8):1165-72. doi: 10.3109/02841860903032809. PMID: 19863225
Dedifferentiated parosteal osteosarcoma: the experience of the Rizzoli Institute.
Bertoni F, Bacchini P, Staals EL, Davidovitz P
Cancer 2005 Jun 1;103(11):2373-82. doi: 10.1002/cncr.21039. PMID: 15852358
The role of resection in the treatment of pulmonary metastases from Ewing's sarcoma.
Lanza LA, Miser JS, Pass HI, Roth JA
J Thorac Cardiovasc Surg 1987 Aug;94(2):181-7. PMID: 3613615

Prognosis

Treatment of 120 adult osteosarcoma patients with metachronous and synchronous metastases: A retrospective series of the French Sarcoma Group.
Lavit E, Aldea M, Piperno-Neumann S, Firmin N, Italiano A, Isambert N, Kurtz JE, Delcambre C, Lebrun V, Soibinet-Oudot P, Chevreau C, Bompas E, Le Maignan C, Boudou-Rouquette P, Le Cesne A, Mancini J, Blay JY, Duffaud F
Int J Cancer 2022 Feb 15;150(4):645-653. Epub 2021 Oct 5 doi: 10.1002/ijc.33823. PMID: 34562271
Multicentric osteosarcoma.
Hameed S, Vijayan S, Naik M, Rao S
Singapore Med J 2012 Oct;53(10):e214-7. PMID: 23112033
Multicentric osteosarcoma: clinicopathologic and radiographic study of 56 cases.
Corradi D, Wenger DE, Bertoni F, Bacchini P, Bosio S, Goldoni M, Unni KK, Sim FH, Inwards CY
Am J Clin Pathol 2011 Nov;136(5):799-807. doi: 10.1309/AJCP0V0OATKCNAZP. PMID: 22031320
Osteosarcoma lung metastases detection and principles of multimodal therapy.
Carrle D, Bielack S
Cancer Treat Res 2009;152:165-84. doi: 10.1007/978-1-4419-0284-9_8. PMID: 20213390
Multicentric chondrosarcomas.
Damron TA, Sim FH, Unni KK
Clin Orthop Relat Res 1996 Jul;(328):211-9. doi: 10.1097/00003086-199607000-00033. PMID: 8653959

Clinical prediction guides

CT features of osteosarcoma lung metastasis: a retrospective study of 127 patients.
Silva JAM, Marchiori E, Amorim VB, Barreto MM
J Bras Pneumol 2023;49(2):e20220433. Epub 2023 Apr 28 doi: 10.36416/1806-3756/e20220433. PMID: 37132704Free PMC Article
Evaluation of P-glycoprotein, HER-2/ErbB-2, p53, and Bcl-2 in primary tumor and metachronous lung metastases in patients with high-grade osteosarcoma.
Ferrari S, Bertoni F, Zanella L, Setola E, Bacchini P, Alberghini M, Versari M, Bacci G
Cancer 2004 May 1;100(9):1936-42. doi: 10.1002/cncr.20151. PMID: 15112275
Somatostatin receptor (SSTR) scintigraphy in patients with osteosarcoma.
Ferrari S, Dondi M, Fanti S, Zoboli S, Giacomini S, Mercuri M, Bacci G
Cancer Biother Radiopharm 2003 Oct;18(5):847-51. doi: 10.1089/108497803770418391. PMID: 14629833
The expression of ccn3(nov) gene in musculoskeletal tumors.
Manara MC, Perbal B, Benini S, Strammiello R, Cerisano V, Perdichizzi S, Serra M, Astolfi A, Bertoni F, Alami J, Yeger H, Picci P, Scotlandi K
Am J Pathol 2002 Mar;160(3):849-59. doi: 10.1016/S0002-9440(10)64908-5. PMID: 11891184Free PMC Article
Multicentric chondrosarcomas.
Damron TA, Sim FH, Unni KK
Clin Orthop Relat Res 1996 Jul;(328):211-9. doi: 10.1097/00003086-199607000-00033. PMID: 8653959

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