U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

EBV-Related Hodgkin Lymphoma

MedGen UID:
234225
•Concept ID:
C1333430
•
Neoplastic Process
Synonyms: EBV Related Hodgkin's Lymphoma; EBV-Related Hodgkin's Lymphoma; Epstein-Barr Virus Related Hodgkin's Lymphoma; Epstein-Barr Virus-Related Hodgkin Lymphoma; Epstein-Barr Virus-Related Hodgkin's Lymphoma

Definition

Hodgkin lymphoma that is caused by Epstein-Barr virus infection. [from NCI]

Professional guidelines

PubMed

Current Treatment Options for Older Patients with Hodgkin Lymphoma.
Carter J, David KA, Kritharis A, Evens AM
Curr Treat Options Oncol 2020 Apr 23;21(5):42. doi: 10.1007/s11864-020-00745-9. PMID: 32328822
In situ hybridisation for Epstein-Barr virus as a differential diagnostic tool for T- and natural killer/T-cell lymphomas in non-immunocompromised patients.
Chuang SS
Pathology 2014 Dec;46(7):581-91. doi: 10.1097/PAT.0000000000000161. PMID: 25393247
EBV-related lymphomas: new approaches to treatment.
Kanakry JA, Ambinder RF
Curr Treat Options Oncol 2013 Jun;14(2):224-36. doi: 10.1007/s11864-013-0231-y. PMID: 23549980Free PMC Article

Recent clinical studies

Etiology

Primary Epstein-Barr virus infection with and without infectious mononucleosis.
Rostgaard K, Balfour HH Jr, Jarrett R, Erikstrup C, Pedersen O, Ullum H, Nielsen LP, Voldstedlund M, Hjalgrim H
PLoS One 2019;14(12):e0226436. Epub 2019 Dec 17 doi: 10.1371/journal.pone.0226436. PMID: 31846480Free PMC Article
Epstein-Barr Virus (EBV)-Related Lymphoproliferative Disorders in Ataxia Telangiectasia: Does ATM Regulate EBV Life Cycle?
Tatfi M, Hermine O, Suarez F
Front Immunol 2018;9:3060. Epub 2019 Jan 4 doi: 10.3389/fimmu.2018.03060. PMID: 30662441Free PMC Article
Human immunodeficiency virus (HIV) and Epstein-Barr virus (EBV) related lymphomas, pathology view point.
Linke-Serinsöz E, Fend F, Quintanilla-Martinez L
Semin Diagn Pathol 2017 Jul;34(4):352-363. Epub 2017 Apr 7 doi: 10.1053/j.semdp.2017.04.003. PMID: 28506687
Epstein-Barr virus (EBV)-associated lymphoid lesions of the head and neck.
Auerbach A, Aguilera NS
Semin Diagn Pathol 2015 Jan;32(1):12-22. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2014.12.001. PMID: 25804341
Epstein-Barr virus vaccines.
Morgan AJ
Vaccine 1992;10(9):563-71. doi: 10.1016/0264-410x(92)90434-l. PMID: 1323899

Diagnosis

NK-/T-cell lymphomas.
Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356Free PMC Article
Current Treatment Options for Older Patients with Hodgkin Lymphoma.
Carter J, David KA, Kritharis A, Evens AM
Curr Treat Options Oncol 2020 Apr 23;21(5):42. doi: 10.1007/s11864-020-00745-9. PMID: 32328822
Novel EBV LMP-2-affibody and affitoxin in molecular imaging and targeted therapy of nasopharyngeal carcinoma.
Zhu S, Chen J, Xiong Y, Kamara S, Gu M, Tang W, Chen S, Dong H, Xue X, Zheng ZM, Zhang L
PLoS Pathog 2020 Jan;16(1):e1008223. Epub 2020 Jan 6 doi: 10.1371/journal.ppat.1008223. PMID: 31905218Free PMC Article
Primary CNS lymphoma in HIV infection.
Brandsma D, Bromberg JEC
Handb Clin Neurol 2018;152:177-186. doi: 10.1016/B978-0-444-63849-6.00014-1. PMID: 29604975
Epstein-Barr virus (EBV)-associated lymphoid lesions of the head and neck.
Auerbach A, Aguilera NS
Semin Diagn Pathol 2015 Jan;32(1):12-22. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2014.12.001. PMID: 25804341

Therapy

Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
NK-/T-cell lymphomas.
Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356Free PMC Article
Novel EBV LMP-2-affibody and affitoxin in molecular imaging and targeted therapy of nasopharyngeal carcinoma.
Zhu S, Chen J, Xiong Y, Kamara S, Gu M, Tang W, Chen S, Dong H, Xue X, Zheng ZM, Zhang L
PLoS Pathog 2020 Jan;16(1):e1008223. Epub 2020 Jan 6 doi: 10.1371/journal.ppat.1008223. PMID: 31905218Free PMC Article
Primary CNS lymphoma in HIV infection.
Brandsma D, Bromberg JEC
Handb Clin Neurol 2018;152:177-186. doi: 10.1016/B978-0-444-63849-6.00014-1. PMID: 29604975
Immunotherapy for EBV-associated malignancies.
Merlo A, Turrini R, Dolcetti R, Zanovello P, Rosato A
Int J Hematol 2011 Mar;93(3):281-293. Epub 2011 Feb 19 doi: 10.1007/s12185-011-0782-2. PMID: 21336546

Prognosis

NK-/T-cell lymphomas.
Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356Free PMC Article
Epstein-Barr Virus (EBV)-Related Lymphoproliferative Disorders in Ataxia Telangiectasia: Does ATM Regulate EBV Life Cycle?
Tatfi M, Hermine O, Suarez F
Front Immunol 2018;9:3060. Epub 2019 Jan 4 doi: 10.3389/fimmu.2018.03060. PMID: 30662441Free PMC Article
Primary CNS lymphoma in HIV infection.
Brandsma D, Bromberg JEC
Handb Clin Neurol 2018;152:177-186. doi: 10.1016/B978-0-444-63849-6.00014-1. PMID: 29604975
Epstein-Barr virus (EBV)-associated lymphoid lesions of the head and neck.
Auerbach A, Aguilera NS
Semin Diagn Pathol 2015 Jan;32(1):12-22. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2014.12.001. PMID: 25804341
Matrix metalloproteinase-9 is consistently expressed in Hodgkin/Reed-Sternberg cells and has no impact on survival in patients with Epstein-Barr virus (EBV)-related and non-related Hodgkin lymphoma in Brazil.
Souza EM, Baiocchi OC, Zanichelli MA, Alves AC, Assis MG, Silva JM, Dobo C, Oliveira JS
Med Oncol 2012 Sep;29(3):2148-52. Epub 2011 Sep 16 doi: 10.1007/s12032-011-0063-1. PMID: 21922298

Clinical prediction guides

Estimating the global burden of Epstein-Barr virus-related cancers.
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
NK-/T-cell lymphomas.
Wang H, Fu BB, Gale RP, Liang Y
Leukemia 2021 Sep;35(9):2460-2468. Epub 2021 Jun 11 doi: 10.1038/s41375-021-01313-2. PMID: 34117356Free PMC Article
Primary Epstein-Barr virus infection with and without infectious mononucleosis.
Rostgaard K, Balfour HH Jr, Jarrett R, Erikstrup C, Pedersen O, Ullum H, Nielsen LP, Voldstedlund M, Hjalgrim H
PLoS One 2019;14(12):e0226436. Epub 2019 Dec 17 doi: 10.1371/journal.pone.0226436. PMID: 31846480Free PMC Article
Human immunodeficiency virus (HIV) and Epstein-Barr virus (EBV) related lymphomas, pathology view point.
Linke-Serinsöz E, Fend F, Quintanilla-Martinez L
Semin Diagn Pathol 2017 Jul;34(4):352-363. Epub 2017 Apr 7 doi: 10.1053/j.semdp.2017.04.003. PMID: 28506687
Epstein-Barr virus (EBV)-associated lymphoid lesions of the head and neck.
Auerbach A, Aguilera NS
Semin Diagn Pathol 2015 Jan;32(1):12-22. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2014.12.001. PMID: 25804341

Recent systematic reviews

EBV Positivity and Programmed Death-ligand 1 Expression in Diffuse Large B-cell Lymphoma: A Systematic Review.
Barzyk GA, Sheriff V
Anticancer Res 2020 Nov;40(11):5951-5968. doi: 10.21873/anticanres.14616. PMID: 33109533

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...