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Adenocarcinoma In Situ in Tubular Adenoma

MedGen UID:
235114
•Concept ID:
C1377632
•
Neoplastic Process
Synonym: Adenocarcinoma in situ in tubular adenoma
SNOMED CT: Adenocarcinoma in situ in tubular adenoma (60286009)

Definition

An intraepithelial adenocarcinoma arising from a tubular adenoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdenocarcinoma In Situ in Tubular Adenoma

Recent clinical studies

Etiology

Clinicopathologic and Molecular Characterization of Anorectal Neuroendocrine Carcinomas Reveals Human Papillomavirus, p53, and c-Myc as Alternative Mechanisms of Carcinogenesis.
Cox AJ, Crowe WE, Yang Q, Zhang B, Oltvai ZN, Liao X
Mod Pathol 2023 Nov;36(11):100295. Epub 2023 Jul 29 doi: 10.1016/j.modpat.2023.100295. PMID: 37517480
Primary HPV-Associated Enteric-Type Adenocarcinoma of Vagina: A Case Report.
Felicelli C, Strickland A, Wei JJ
Int J Surg Pathol 2023 Oct;31(7):1393-1397. Epub 2023 Jan 24 doi: 10.1177/10668969221150529. PMID: 36694422
Syringocystadenocarcinoma papilliferum: Clinicopathologic analysis of 10 cases.
Zhang Y, Kong YY, Cai X, Shen XX, Kong JC
J Cutan Pathol 2017 Jun;44(6):538-543. Epub 2017 Apr 17 doi: 10.1111/cup.12934. PMID: 28337777
The frequency of advanced adenoma in consulting patients: a nationwide survey in Iceland (2003-2006).
Rubio CA, Kristjansdottir S, Thodleifsson B, Olafsdóttir E, Jonasson JG
Colorectal Dis 2012 Sep;14(9):e595-602. doi: 10.1111/j.1463-1318.2012.03119.x. PMID: 22672531
Gene expression profiling reveals sequential changes in gastric tubular adenoma and carcinoma in situ.
Lee CH, Bang SH, Lee SK, Song KY, Lee IC
World J Gastroenterol 2005 Apr 7;11(13):1937-45. doi: 10.3748/wjg.v11.i13.1937. PMID: 15800983Free PMC Article

Diagnosis

Ancillary immunohistochemical and molecular testing in the classification of cutaneous sweat gland/duct neoplasms: A validation study with emphasis on histomorphologic correlation and pathological diagnosis.
Nguyen AJ, Johnson E, Camilleri M, Wieland C, Lehman JS, Agrawal S, Comfere N, Fadra N, Knudson RA, Greipp P, Halling K, Ray Guo R
Hum Pathol 2024 Aug;150:1-8. Epub 2024 Jun 12 doi: 10.1016/j.humpath.2024.06.006. PMID: 38876201
Syringomatous Adenoma of the Nipple with Associated Invasive Carcinoma: A Case Report.
Pratt D, Sunassee A
S D Med 2022 Jul;75(7):302-303. PMID: 36542569
Nephrogenic Adenoma Intermixed With Urothelial Carcinoma.
Kryvenko ON, Wasco MJ, Williamson SR
Arch Pathol Lab Med 2022 May 1;147(5):552-558. doi: 10.5858/arpa.2021-0620-OA. PMID: 35976666
Perianal Paget's disease as spread from non-invasive colorectal adenomas.
Hutchings D, Windon A, Assarzadegan N, Salimian KJ, Voltaggio L, Montgomery EA
Histopathology 2021 Jan;78(2):276-280. Epub 2020 Sep 23 doi: 10.1111/his.14218. PMID: 32705713Free PMC Article
Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases.
Adsay V, Jang KT, Roa JC, Dursun N, Ohike N, Bagci P, Basturk O, Bandyopadhyay S, Cheng JD, Sarmiento JM, Escalona OT, Goodman M, Kong SY, Terry P
Am J Surg Pathol 2012 Sep;36(9):1279-301. doi: 10.1097/PAS.0b013e318262787c. PMID: 22895264

Prognosis

Ancillary immunohistochemical and molecular testing in the classification of cutaneous sweat gland/duct neoplasms: A validation study with emphasis on histomorphologic correlation and pathological diagnosis.
Nguyen AJ, Johnson E, Camilleri M, Wieland C, Lehman JS, Agrawal S, Comfere N, Fadra N, Knudson RA, Greipp P, Halling K, Ray Guo R
Hum Pathol 2024 Aug;150:1-8. Epub 2024 Jun 12 doi: 10.1016/j.humpath.2024.06.006. PMID: 38876201
Perianal Paget's disease as spread from non-invasive colorectal adenomas.
Hutchings D, Windon A, Assarzadegan N, Salimian KJ, Voltaggio L, Montgomery EA
Histopathology 2021 Jan;78(2):276-280. Epub 2020 Sep 23 doi: 10.1111/his.14218. PMID: 32705713Free PMC Article
Syringocystadenocarcinoma papilliferum: Clinicopathologic analysis of 10 cases.
Zhang Y, Kong YY, Cai X, Shen XX, Kong JC
J Cutan Pathol 2017 Jun;44(6):538-543. Epub 2017 Apr 17 doi: 10.1111/cup.12934. PMID: 28337777
Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases.
Adsay V, Jang KT, Roa JC, Dursun N, Ohike N, Bagci P, Basturk O, Bandyopadhyay S, Cheng JD, Sarmiento JM, Escalona OT, Goodman M, Kong SY, Terry P
Am J Surg Pathol 2012 Sep;36(9):1279-301. doi: 10.1097/PAS.0b013e318262787c. PMID: 22895264
The frequency of advanced adenoma in consulting patients: a nationwide survey in Iceland (2003-2006).
Rubio CA, Kristjansdottir S, Thodleifsson B, Olafsdóttir E, Jonasson JG
Colorectal Dis 2012 Sep;14(9):e595-602. doi: 10.1111/j.1463-1318.2012.03119.x. PMID: 22672531

Clinical prediction guides

Ancillary immunohistochemical and molecular testing in the classification of cutaneous sweat gland/duct neoplasms: A validation study with emphasis on histomorphologic correlation and pathological diagnosis.
Nguyen AJ, Johnson E, Camilleri M, Wieland C, Lehman JS, Agrawal S, Comfere N, Fadra N, Knudson RA, Greipp P, Halling K, Ray Guo R
Hum Pathol 2024 Aug;150:1-8. Epub 2024 Jun 12 doi: 10.1016/j.humpath.2024.06.006. PMID: 38876201
Circulating miR-182 is a biomarker of colorectal adenocarcinoma progression.
Perilli L, Vicentini C, Agostini M, Pizzini S, Pizzi M, D'Angelo E, Bortoluzzi S, Mandruzzato S, Mammano E, Rugge M, Nitti D, Scarpa A, Fassan M, Zanovello P
Oncotarget 2014 Aug 30;5(16):6611-9. doi: 10.18632/oncotarget.2245. PMID: 25115394Free PMC Article
The frequency of advanced adenoma in consulting patients: a nationwide survey in Iceland (2003-2006).
Rubio CA, Kristjansdottir S, Thodleifsson B, Olafsdóttir E, Jonasson JG
Colorectal Dis 2012 Sep;14(9):e595-602. doi: 10.1111/j.1463-1318.2012.03119.x. PMID: 22672531
PDCD4 nuclear loss inversely correlates with miR-21 levels in colon carcinogenesis.
Fassan M, Pizzi M, Giacomelli L, Mescoli C, Ludwig K, Pucciarelli S, Rugge M
Virchows Arch 2011 Apr;458(4):413-9. Epub 2011 Jan 29 doi: 10.1007/s00428-011-1046-5. PMID: 21279518
Computer-assisted pathology of intraepithelial adenocarcinoma and related lesions: 3-D distribution, structural aberration and discrimination.
Takahashi T, Chiba R, Mori M, Furukawa T, Suzuki M, Tezuka F
J Cell Biochem Suppl 1995;23:25-32. doi: 10.1002/jcb.240590905. PMID: 8747375

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