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Lung hilum carcinoma

MedGen UID:
235266
•Concept ID:
C1334445
•
Neoplastic Process
Synonyms: carcinoma of lung hilus; Hilar Lung Carcinoma; hilar lung carcinoma; Lung Hilum Carcinoma; lung hilum carcinoma; lung hilus carcinoma
 
Monarch Initiative: MONDO:0004499

Definition

A lung carcinoma arising from the hilum of the lung. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLung hilum carcinoma

Professional guidelines

PubMed

Patterns of Treatment Failure after Concurrent Chemoradiotherapy or Adjuvant Radiotherapy in Patients with Locally Advanced Cervical Cancer.
Wang Y, Zhang T, Peng S, Zhou R, Li L, Kou L, Yuan M, Li M
Oncol Res Treat 2021;44(3):76-85. Epub 2021 Jan 18 doi: 10.1159/000513170. PMID: 33461197
Salvage treatment of NSCLC recurrence after first-line chemotherapy failure: Iodine-125 seed brachytherapy or microwave ablation?
Liu B, Wang Y, Tian S, Hertzanu Y, Zhao X, Li Y
Thorac Cancer 2020 Mar;11(3):697-703. Epub 2020 Jan 29 doi: 10.1111/1759-7714.13320. PMID: 31995853Free PMC Article
Microwave ablation therapy: clinical utility in treatment of pulmonary metastases.
Vogl TJ, Naguib NN, Gruber-Rouh T, Koitka K, Lehnert T, Nour-Eldin NE
Radiology 2011 Nov;261(2):643-51. doi: 10.1148/radiol.11101643. PMID: 22012906

Recent clinical studies

Etiology

MSCT findings of primary Pulmonary mucoepidermoid carcinoma.
Liu Y, Liu M, Nie Y
Ann Med 2023;55(2):2263869. Epub 2023 Oct 2 doi: 10.1080/07853890.2023.2263869. PMID: 37783202Free PMC Article
Trans-Inferior-Pulmonary-Ligament Single-Direction Thoracoscopic RS9 Segmentectomy: Application of Stem-Branch Method for Tracking Anatomy.
Zhu Y, Pu Q, Liu C, Mei J, Liu L
Ann Surg Oncol 2020 Aug;27(8):3092-3093. Epub 2020 Mar 9 doi: 10.1245/s10434-020-08309-9. PMID: 32152779
Salvage treatment of NSCLC recurrence after first-line chemotherapy failure: Iodine-125 seed brachytherapy or microwave ablation?
Liu B, Wang Y, Tian S, Hertzanu Y, Zhao X, Li Y
Thorac Cancer 2020 Mar;11(3):697-703. Epub 2020 Jan 29 doi: 10.1111/1759-7714.13320. PMID: 31995853Free PMC Article
Margin Distance Does Not Influence Recurrence and Survival After Wedge Resection for Lung Cancer.
Maurizi G, D'Andrilli A, Ciccone AM, Ibrahim M, Andreetti C, Tierno S, Poggi C, Menna C, Venuta F, Rendina EA
Ann Thorac Surg 2015 Sep;100(3):918-24; discussion 924-5. Epub 2015 Jul 21 doi: 10.1016/j.athoracsur.2015.04.064. PMID: 26209486
Cytologic findings of NUT midline carcinoma in the hilum of the lung.
Policarpio-Nicolas ML, de Leon EM, Jagirdar J
Diagn Cytopathol 2015 Sep;43(9):739-42. Epub 2015 Jul 3 doi: 10.1002/dc.23291. PMID: 26138851

Diagnosis

Atypical clinical and radiologic findings in a patient with brain metastatic lesions.
Halil E, Viteva E, Vasilev G, Shukerski K, Atanassova P
Folia Med (Plovdiv) 2023 Oct 31;65(5):844-848. doi: 10.3897/folmed.65.e84810. PMID: 38351770
MSCT findings of primary Pulmonary mucoepidermoid carcinoma.
Liu Y, Liu M, Nie Y
Ann Med 2023;55(2):2263869. Epub 2023 Oct 2 doi: 10.1080/07853890.2023.2263869. PMID: 37783202Free PMC Article
Salvage treatment of NSCLC recurrence after first-line chemotherapy failure: Iodine-125 seed brachytherapy or microwave ablation?
Liu B, Wang Y, Tian S, Hertzanu Y, Zhao X, Li Y
Thorac Cancer 2020 Mar;11(3):697-703. Epub 2020 Jan 29 doi: 10.1111/1759-7714.13320. PMID: 31995853Free PMC Article
Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature.
Al-Obaidy KI, Idrees MT, Grignon DJ, Ulbright TM
Am J Surg Pathol 2019 May;43(5):670-681. doi: 10.1097/PAS.0000000000001219. PMID: 30676333
Cytologic findings of NUT midline carcinoma in the hilum of the lung.
Policarpio-Nicolas ML, de Leon EM, Jagirdar J
Diagn Cytopathol 2015 Sep;43(9):739-42. Epub 2015 Jul 3 doi: 10.1002/dc.23291. PMID: 26138851

Therapy

Salvage treatment of NSCLC recurrence after first-line chemotherapy failure: Iodine-125 seed brachytherapy or microwave ablation?
Liu B, Wang Y, Tian S, Hertzanu Y, Zhao X, Li Y
Thorac Cancer 2020 Mar;11(3):697-703. Epub 2020 Jan 29 doi: 10.1111/1759-7714.13320. PMID: 31995853Free PMC Article
Stereotactic body radiation therapy for isolated hilar and mediastinal non-small cell lung cancers.
Horne ZD, Richman AH, Dohopolski MJ, Clump DA, Burton SA, Heron DE
Lung Cancer 2018 Jan;115:1-4. Epub 2017 Nov 10 doi: 10.1016/j.lungcan.2017.10.014. PMID: 29290248
Total thoracoscopic posterior basal segmentectomy for primary lung cancer.
Nishio W, Tane K, Uchino K, Yoshimura M
Multimed Man Cardiothorac Surg 2014;2014 Epub 2014 Dec 12 doi: 10.1093/mmcts/mmu025. PMID: 25500769
Segmentectomy for c-T1N0M0 non-small cell lung cancer.
Nomori H
Surg Today 2014 May;44(5):812-9. Epub 2013 Jun 29 doi: 10.1007/s00595-013-0649-7. PMID: 23812915
Post-operative radiation therapy (PORT) in completely resected non-small-cell lung cancer.
Krupitskaya Y, Loo BW Jr
Curr Treat Options Oncol 2008 Dec;9(4-6):343-56. Epub 2009 Apr 22 doi: 10.1007/s11864-009-0090-8. PMID: 19387842

Prognosis

Lobectomy versus segmentectomy: a propensity score-matched comparison of postoperative complications, pulmonary function and prognosis.
Nomori H, Yamazaki I, Machida Y, Otsuki A, Cong Y, Sugimura H, Oyama Y
Interact Cardiovasc Thorac Surg 2022 Jan 6;34(1):57-65. Epub 2021 Oct 25 doi: 10.1093/icvts/ivab212. PMID: 34999814Free PMC Article
Two-port intrapericardial left VATS pneumonectomy.
Nicotra S, Comacchio G, Natale G, Pangoni A, Rebusso A, Rea F
Multimed Man Cardiothorac Surg 2019 Dec 20;2019 doi: 10.1510/mmcts.2019.047. PMID: 31869011
Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature.
Al-Obaidy KI, Idrees MT, Grignon DJ, Ulbright TM
Am J Surg Pathol 2019 May;43(5):670-681. doi: 10.1097/PAS.0000000000001219. PMID: 30676333
Margin Distance Does Not Influence Recurrence and Survival After Wedge Resection for Lung Cancer.
Maurizi G, D'Andrilli A, Ciccone AM, Ibrahim M, Andreetti C, Tierno S, Poggi C, Menna C, Venuta F, Rendina EA
Ann Thorac Surg 2015 Sep;100(3):918-24; discussion 924-5. Epub 2015 Jul 21 doi: 10.1016/j.athoracsur.2015.04.064. PMID: 26209486
Segmentectomy for c-T1N0M0 non-small cell lung cancer.
Nomori H
Surg Today 2014 May;44(5):812-9. Epub 2013 Jun 29 doi: 10.1007/s00595-013-0649-7. PMID: 23812915

Clinical prediction guides

Lobectomy versus segmentectomy: a propensity score-matched comparison of postoperative complications, pulmonary function and prognosis.
Nomori H, Yamazaki I, Machida Y, Otsuki A, Cong Y, Sugimura H, Oyama Y
Interact Cardiovasc Thorac Surg 2022 Jan 6;34(1):57-65. Epub 2021 Oct 25 doi: 10.1093/icvts/ivab212. PMID: 34999814Free PMC Article
Staple Line Thickening After Sublobar Resection: Reaction or Recurrence?
Sun B, Kamel MK, Nasar A, Harrison S, Lee B, Port JL, Altorki NK, Stiles BM
Ann Thorac Surg 2020 Jun;109(6):1670-1676. Epub 2020 Feb 11 doi: 10.1016/j.athoracsur.2019.12.065. PMID: 32057814
Relationship between the Size and Location of the Mass and Hilar and Mediastinal Lymph Node Metastasis in Early and Locally Advanced Non-small Cell Lung Cancer.
Kuzucuoglu M, Gokyer A, Kula O, Yekdes AC, Sunal BS, Karamustafaoglu YA, Yoruk Y, Cicin I
J Coll Physicians Surg Pak 2020 Feb;30(2):172-176. doi: 10.29271/jcpsp.2020.02.172. PMID: 32036826
Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature.
Al-Obaidy KI, Idrees MT, Grignon DJ, Ulbright TM
Am J Surg Pathol 2019 May;43(5):670-681. doi: 10.1097/PAS.0000000000001219. PMID: 30676333
Sequential multimodality bronchoscopic investigation of peripheral pulmonary lesions.
Steinfort DP, Bonney A, See K, Irving LB
Eur Respir J 2016 Feb;47(2):607-14. Epub 2015 Nov 5 doi: 10.1183/13993003.00786-2015. PMID: 26541529

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