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Small intestinal intraepithelial neoplasia

MedGen UID:
236822
•Concept ID:
C1335999
•
Neoplastic Process
Synonyms: Small Intestinal Dysplasia; small intestinal dysplasia; Small Intestinal Intraepithelial Neoplasia; small intestinal intraepithelial neoplasia
 
Monarch Initiative: MONDO:0006419

Definition

A precancerous neoplastic process that affects the small intestine. It is characterized by low or high grade dysplasia of the mucosal epithelium. There is no evidence of invasion. [from NCI]

Professional guidelines

PubMed

Expected value of artificial intelligence in gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.
Messmann H, Bisschops R, Antonelli G, Libânio D, Sinonquel P, Abdelrahim M, Ahmad OF, Areia M, Bergman JJGHM, Bhandari P, Boskoski I, Dekker E, Domagk D, Ebigbo A, Eelbode T, Eliakim R, Häfner M, Haidry RJ, Jover R, Kaminski MF, Kuvaev R, Mori Y, Palazzo M, Repici A, Rondonotti E, Rutter MD, Saito Y, Sharma P, Spada C, Spadaccini M, Veitch A, Gralnek IM, Hassan C, Dinis-Ribeiro M
Endoscopy 2022 Dec;54(12):1211-1231. Epub 2022 Oct 21 doi: 10.1055/a-1950-5694. PMID: 36270318
A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas.
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article
Impact of staging on treatment of pancreatic and ampullary cancer.
Karl RC, Carey LC
Endoscopy 1993 Jan;25(1):69-74. doi: 10.1055/s-2007-1009127. PMID: 8384102

Recent clinical studies

Etiology

Long-term outcomes of endoscopic papillectomy for ampullary adenoma with high-grade dysplasia or adenocarcinoma: a propensity score-matched analysis.
Yoon SB, Jung MK, Lee YS, Park JK, Jang DK, Lee JM, Lee HS, Shin DW, Lee JC, Hwang JH
Surg Endosc 2023 May;37(5):3522-3530. Epub 2022 Dec 31 doi: 10.1007/s00464-022-09856-w. PMID: 36587061
Exosomal miRNA signatures of pancreatic lesions.
Vicentini C, Calore F, Nigita G, Fadda P, Simbolo M, Sperandio N, Luchini C, Lawlor RT, Croce CM, Corbo V, Fassan M, Scarpa A
BMC Gastroenterol 2020 May 6;20(1):137. doi: 10.1186/s12876-020-01287-y. PMID: 32375666Free PMC Article
Transduodenal excision of ampullary tumours.
Bohra AK, McKie L, Diamond T
Ulster Med J 2002 Nov;71(2):121-7. PMID: 12513008Free PMC Article
Duodenal villous tumors.
Bjork KJ, Davis CJ, Nagorney DM, Mucha P Jr
Arch Surg 1990 Aug;125(8):961-5. doi: 10.1001/archsurg.1990.01410200019001. PMID: 2378560
Do all colorectal carcinomas arise in preexisting adenomas?
Jass JR
World J Surg 1989 Jan-Feb;13(1):45-51. doi: 10.1007/BF01671153. PMID: 2658353

Diagnosis

Expected value of artificial intelligence in gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.
Messmann H, Bisschops R, Antonelli G, Libânio D, Sinonquel P, Abdelrahim M, Ahmad OF, Areia M, Bergman JJGHM, Bhandari P, Boskoski I, Dekker E, Domagk D, Ebigbo A, Eelbode T, Eliakim R, Häfner M, Haidry RJ, Jover R, Kaminski MF, Kuvaev R, Mori Y, Palazzo M, Repici A, Rondonotti E, Rutter MD, Saito Y, Sharma P, Spada C, Spadaccini M, Veitch A, Gralnek IM, Hassan C, Dinis-Ribeiro M
Endoscopy 2022 Dec;54(12):1211-1231. Epub 2022 Oct 21 doi: 10.1055/a-1950-5694. PMID: 36270318
Prognostic impact of circulating tumor cells in patients with ampullary cancer.
Sun B, Liu H, Wang S, Xiang J, Liu X
J Cell Physiol 2018 Jun;233(6):5014-5022. Epub 2018 Jan 4 doi: 10.1002/jcp.26353. PMID: 29215725Free PMC Article
A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas.
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article
An introduction to mucin-producing tumors of the pancreas: why they deserve more attention.
Takada T, Yasuda H, Amano H, Yoshida M, Hijikata H, Takada K
Hepatogastroenterology 1998 Nov-Dec;45(24):1967-72. PMID: 9951849
Duodenoscopy and endoscopic retrograde choledochopancreatography: present position in relation to periampullary and pancreatic cancer.
Blumgart LH
J Surg Oncol 1975;7(2):107-19. doi: 10.1002/jso.2930070206. PMID: 168436

Therapy

Videourodynamic evaluation of intracorporeally reconstructed orthotopic U-shaped ileal neobladders.
Palleschi G, Pastore AL, Ripoli A, Silvestri L, Petrozza V, Carbone A
Urology 2015 Apr;85(4):883-9. doi: 10.1016/j.urology.2014.09.067. PMID: 25817111
Colonic in situ mantle cell lymphoma.
Neto AG, Oroszi G, Protiva P, Rose M, Shafi N, Torres R
Ann Diagn Pathol 2012 Dec;16(6):508-14. Epub 2011 Aug 12 doi: 10.1016/j.anndiagpath.2011.05.001. PMID: 21840231
Short-term results of 42 endoscopic ampullectomies: a single-center experience.
Jeanniard-Malet O, Caillol F, Pesenti C, Bories E, Monges G, Giovannini M
Scand J Gastroenterol 2011 Jul;46(7-8):1014-9. Epub 2011 Apr 15 doi: 10.3109/00365521.2011.571711. PMID: 21492053
Duodenoscopy and endoscopic retrograde choledochopancreatography: present position in relation to periampullary and pancreatic cancer.
Blumgart LH
J Surg Oncol 1975;7(2):107-19. doi: 10.1002/jso.2930070206. PMID: 168436
Malignant tumours following immunosuppressive therapy.
Pritzker KP, Huang SN, Marshall KG
Can Med Assoc J 1970 Dec 19;103(13):1362-5. PMID: 4923839Free PMC Article

Prognosis

Exosomal miRNA signatures of pancreatic lesions.
Vicentini C, Calore F, Nigita G, Fadda P, Simbolo M, Sperandio N, Luchini C, Lawlor RT, Croce CM, Corbo V, Fassan M, Scarpa A
BMC Gastroenterol 2020 May 6;20(1):137. doi: 10.1186/s12876-020-01287-y. PMID: 32375666Free PMC Article
Prognostic impact of circulating tumor cells in patients with ampullary cancer.
Sun B, Liu H, Wang S, Xiang J, Liu X
J Cell Physiol 2018 Jun;233(6):5014-5022. Epub 2018 Jan 4 doi: 10.1002/jcp.26353. PMID: 29215725Free PMC Article
An introduction to mucin-producing tumors of the pancreas: why they deserve more attention.
Takada T, Yasuda H, Amano H, Yoshida M, Hijikata H, Takada K
Hepatogastroenterology 1998 Nov-Dec;45(24):1967-72. PMID: 9951849
Duodenal villous tumors.
Bjork KJ, Davis CJ, Nagorney DM, Mucha P Jr
Arch Surg 1990 Aug;125(8):961-5. doi: 10.1001/archsurg.1990.01410200019001. PMID: 2378560
Duodenoscopy and endoscopic retrograde choledochopancreatography: present position in relation to periampullary and pancreatic cancer.
Blumgart LH
J Surg Oncol 1975;7(2):107-19. doi: 10.1002/jso.2930070206. PMID: 168436

Clinical prediction guides

Long-term outcomes of endoscopic papillectomy for ampullary adenoma with high-grade dysplasia or adenocarcinoma: a propensity score-matched analysis.
Yoon SB, Jung MK, Lee YS, Park JK, Jang DK, Lee JM, Lee HS, Shin DW, Lee JC, Hwang JH
Surg Endosc 2023 May;37(5):3522-3530. Epub 2022 Dec 31 doi: 10.1007/s00464-022-09856-w. PMID: 36587061
A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas.
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article
Videourodynamic evaluation of intracorporeally reconstructed orthotopic U-shaped ileal neobladders.
Palleschi G, Pastore AL, Ripoli A, Silvestri L, Petrozza V, Carbone A
Urology 2015 Apr;85(4):883-9. doi: 10.1016/j.urology.2014.09.067. PMID: 25817111
Cyclin E overexpression and amplification in human tumours.
Schraml P, Bucher C, Bissig H, Nocito A, Haas P, Wilber K, Seelig S, Kononen J, Mihatsch MJ, Dirnhofer S, Sauter G
J Pathol 2003 Jul;200(3):375-82. doi: 10.1002/path.1356. PMID: 12845634
Urethral recurrence in patients with orthotopic ileal neobladders.
Freeman JA, Tarter TA, Esrig D, Stein JP, Elmajian DA, Chen SC, Groshen S, Lieskovsky G, Skinner DG
J Urol 1996 Nov;156(5):1615-9. PMID: 8863551

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