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Stage IVB Liver Cancer

MedGen UID:
236925
•Concept ID:
C1336377
•
Neoplastic Process
Synonym: Stage IVB Liver Carcinoma

Definition

Stage IVB carcinoma of the liver according to the American Joint Committee on Cancer, 7th and 8th editions. [from NCI]

Professional guidelines

PubMed

Impact of Socioeconomic Factors on Prognosis and Clinical Management in Patients with Hepatocellular Carcinoma.
Su BB, Zhou BH, Bai DS, Qian JJ, Zhang C, Jin SJ, Jiang GQ
Turk J Gastroenterol 2021 Aug;32(8):667-677. doi: 10.5152/tjg.2021.20617. PMID: 34528880Free PMC Article
Distribution of tumor stage and initial treatment modality in patients with primary hepatocellular carcinoma.
Xiang X, Zhong JH, Wang YY, You XM, Ma L, Xiang BD, Li LQ
Clin Transl Oncol 2017 Jul;19(7):891-897. Epub 2017 Feb 3 doi: 10.1007/s12094-017-1621-6. PMID: 28160206
U.K. consensus statement on safe clinical prescribing of bexarotene for patients with cutaneous T-cell lymphoma.
Scarisbrick JJ, Morris S, Azurdia R, Illidge T, Parry E, Graham-Brown R, Cowan R, Gallop-Evans E, Wachsmuth R, Eagle M, Wierzbicki AS, Soran H, Whittaker S, Wain EM
Br J Dermatol 2013 Jan;168(1):192-200. Epub 2012 Dec 3 doi: 10.1111/bjd.12042. PMID: 22963233

Recent clinical studies

Etiology

Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.
Hong L, Aminu M, Li S, Lu X, Petranovic M, Saad MB, Chen P, Qin K, Varghese S, Rinsurongkawong W, Rinsurongkawong V, Spelman A, Elamin YY, Negrao MV, Skoulidis F, Gay CM, Cascone T, Gandhi SJ, Lin SH, Lee PP, Carter BW, Wu CC, Antonoff MB, Sepesi B, Lewis J, Gibbons DL, Vaporciyan AA, Le X, Jack Lee J, Roy-Chowdhuri S, Routbort MJ, Gainor JF, Heymach JV, Lou Y, Wu J, Zhang J, Vokes NI
Nat Commun 2023 Feb 8;14(1):695. doi: 10.1038/s41467-023-36328-z. PMID: 36755027Free PMC Article
Metastatic extent-specific prognosis of women with stage IVB cervical cancer: multiple versus single distant organ involvement.
Joh S, Violette CJ, Khetan VU, Tavakoli A, Jooya ND, Cahoon SS, Klar M, Roman LD, Matsuo K
Arch Gynecol Obstet 2023 Feb;307(2):533-540. Epub 2022 May 21 doi: 10.1007/s00404-022-06611-3. PMID: 35596748
Laparoscopic segment 4b+5 liver resection for stage T3 gallbladder cancer.
Huang L, Zhang C, Tian Y, Liao C, Yan M, Qiu F, Zhou S, Lai Z, Wang Y, Lin Y, Chen S
Surg Endosc 2022 Dec;36(12):8893-8907. Epub 2022 Jul 29 doi: 10.1007/s00464-022-09325-4. PMID: 35906460
Resection of oesophageal and oesophagogastric junction cancer liver metastases - a summary of current evidence.
Weiss ARR, Donlon NE, Schlitt HJ, Hackl C
Langenbecks Arch Surg 2022 May;407(3):947-955. Epub 2021 Dec 3 doi: 10.1007/s00423-021-02387-3. PMID: 34860291Free PMC Article
Pan-cancer analysis of prognostic metastatic phenotypes.
Zaorsky NG, Wang X, Garrett SM, Lehrer EJ, Lin C, DeGraff DJ, Spratt DE, Trifiletti DM, Kishan AU, Showalter TN, Park HS, Yang JT, Chinchilli VM, Wang M
Int J Cancer 2022 Jan 1;150(1):132-141. Epub 2021 Aug 27 doi: 10.1002/ijc.33744. PMID: 34287840Free PMC Article

Diagnosis

Panorama of multidetector-row computed tomography findings of carcinoma gall bladder - A retrospective observational study.
Mohakud S, Sidhu S, Deep N, Naik S
J Cancer Res Ther 2022 Apr-Jun;18(3):661-667. doi: 10.4103/jcrt.jcrt_235_21. PMID: 35900538
CyberKnife Stereotactic Radiosurgery for Cholangiocarcinoma.
Harada Y, Miyazaki S
Intern Med 2018 May 15;57(10):1411-1414. Epub 2017 Dec 27 doi: 10.2169/internalmedicine.9572-17. PMID: 29279492Free PMC Article
Barcelona clinic liver cancer-stage C hepatocellular carcinoma: A novel approach to subclassification and treatment.
Jun CH, Yoon JH, Cho E, Shin SS, Cho SB, Kim HJ, Park CH, Kim HS, Choi SK, Rew JS
Medicine (Baltimore) 2017 Apr;96(17):e6745. doi: 10.1097/MD.0000000000006745. PMID: 28445298Free PMC Article
Systemic involvement in mycosis fungoides.
Burg G
Clin Dermatol 2015 Sep-Oct;33(5):563-71. Epub 2015 Jun 1 doi: 10.1016/j.clindermatol.2015.05.008. PMID: 26321404
Interventional endoscopy, neoadjuvant therapy and the gastroenterologist.
Snady H
Hematol Oncol Clin North Am 2002 Feb;16(1):53-79. doi: 10.1016/s0889-8588(01)00010-7. PMID: 12063829

Therapy

Construction of web-based prediction nomogram models for cancer-specific survival in patients at stage IV of hepatocellular carcinoma depending on SEER database.
Zhan G, Cao P, Peng H
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2023 Oct 28;48(10):1546-1560. doi: 10.11817/j.issn.1672-7347.2023.230040. PMID: 38432884Free PMC Article
Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.
Hong L, Aminu M, Li S, Lu X, Petranovic M, Saad MB, Chen P, Qin K, Varghese S, Rinsurongkawong W, Rinsurongkawong V, Spelman A, Elamin YY, Negrao MV, Skoulidis F, Gay CM, Cascone T, Gandhi SJ, Lin SH, Lee PP, Carter BW, Wu CC, Antonoff MB, Sepesi B, Lewis J, Gibbons DL, Vaporciyan AA, Le X, Jack Lee J, Roy-Chowdhuri S, Routbort MJ, Gainor JF, Heymach JV, Lou Y, Wu J, Zhang J, Vokes NI
Nat Commun 2023 Feb 8;14(1):695. doi: 10.1038/s41467-023-36328-z. PMID: 36755027Free PMC Article
Laparoscopic segment 4b+5 liver resection for stage T3 gallbladder cancer.
Huang L, Zhang C, Tian Y, Liao C, Yan M, Qiu F, Zhou S, Lai Z, Wang Y, Lin Y, Chen S
Surg Endosc 2022 Dec;36(12):8893-8907. Epub 2022 Jul 29 doi: 10.1007/s00464-022-09325-4. PMID: 35906460
Resection of oesophageal and oesophagogastric junction cancer liver metastases - a summary of current evidence.
Weiss ARR, Donlon NE, Schlitt HJ, Hackl C
Langenbecks Arch Surg 2022 May;407(3):947-955. Epub 2021 Dec 3 doi: 10.1007/s00423-021-02387-3. PMID: 34860291Free PMC Article
Barcelona clinic liver cancer-stage C hepatocellular carcinoma: A novel approach to subclassification and treatment.
Jun CH, Yoon JH, Cho E, Shin SS, Cho SB, Kim HJ, Park CH, Kim HS, Choi SK, Rew JS
Medicine (Baltimore) 2017 Apr;96(17):e6745. doi: 10.1097/MD.0000000000006745. PMID: 28445298Free PMC Article

Prognosis

Metastatic extent-specific prognosis of women with stage IVB cervical cancer: multiple versus single distant organ involvement.
Joh S, Violette CJ, Khetan VU, Tavakoli A, Jooya ND, Cahoon SS, Klar M, Roman LD, Matsuo K
Arch Gynecol Obstet 2023 Feb;307(2):533-540. Epub 2022 May 21 doi: 10.1007/s00404-022-06611-3. PMID: 35596748
Laparoscopic segment 4b+5 liver resection for stage T3 gallbladder cancer.
Huang L, Zhang C, Tian Y, Liao C, Yan M, Qiu F, Zhou S, Lai Z, Wang Y, Lin Y, Chen S
Surg Endosc 2022 Dec;36(12):8893-8907. Epub 2022 Jul 29 doi: 10.1007/s00464-022-09325-4. PMID: 35906460
Resection of oesophageal and oesophagogastric junction cancer liver metastases - a summary of current evidence.
Weiss ARR, Donlon NE, Schlitt HJ, Hackl C
Langenbecks Arch Surg 2022 May;407(3):947-955. Epub 2021 Dec 3 doi: 10.1007/s00423-021-02387-3. PMID: 34860291Free PMC Article
Pan-cancer analysis of prognostic metastatic phenotypes.
Zaorsky NG, Wang X, Garrett SM, Lehrer EJ, Lin C, DeGraff DJ, Spratt DE, Trifiletti DM, Kishan AU, Showalter TN, Park HS, Yang JT, Chinchilli VM, Wang M
Int J Cancer 2022 Jan 1;150(1):132-141. Epub 2021 Aug 27 doi: 10.1002/ijc.33744. PMID: 34287840Free PMC Article
Systemic involvement in mycosis fungoides.
Burg G
Clin Dermatol 2015 Sep-Oct;33(5):563-71. Epub 2015 Jun 1 doi: 10.1016/j.clindermatol.2015.05.008. PMID: 26321404

Clinical prediction guides

Construction of web-based prediction nomogram models for cancer-specific survival in patients at stage IV of hepatocellular carcinoma depending on SEER database.
Zhan G, Cao P, Peng H
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2023 Oct 28;48(10):1546-1560. doi: 10.11817/j.issn.1672-7347.2023.230040. PMID: 38432884Free PMC Article
Laparoscopic segment 4b+5 liver resection for stage T3 gallbladder cancer.
Huang L, Zhang C, Tian Y, Liao C, Yan M, Qiu F, Zhou S, Lai Z, Wang Y, Lin Y, Chen S
Surg Endosc 2022 Dec;36(12):8893-8907. Epub 2022 Jul 29 doi: 10.1007/s00464-022-09325-4. PMID: 35906460
Resection of oesophageal and oesophagogastric junction cancer liver metastases - a summary of current evidence.
Weiss ARR, Donlon NE, Schlitt HJ, Hackl C
Langenbecks Arch Surg 2022 May;407(3):947-955. Epub 2021 Dec 3 doi: 10.1007/s00423-021-02387-3. PMID: 34860291Free PMC Article
Pan-cancer analysis of prognostic metastatic phenotypes.
Zaorsky NG, Wang X, Garrett SM, Lehrer EJ, Lin C, DeGraff DJ, Spratt DE, Trifiletti DM, Kishan AU, Showalter TN, Park HS, Yang JT, Chinchilli VM, Wang M
Int J Cancer 2022 Jan 1;150(1):132-141. Epub 2021 Aug 27 doi: 10.1002/ijc.33744. PMID: 34287840Free PMC Article
Gallbladder neuroendocrine carcinoma: A single center experience.
Chu H, Zhang C, Shi Y, Wu W, Hu Z, Zhang J, Huang D
Medicine (Baltimore) 2020 Sep 4;99(36):e21912. doi: 10.1097/MD.0000000000021912. PMID: 32899024Free PMC Article

Recent systematic reviews

Resection of oesophageal and oesophagogastric junction cancer liver metastases - a summary of current evidence.
Weiss ARR, Donlon NE, Schlitt HJ, Hackl C
Langenbecks Arch Surg 2022 May;407(3):947-955. Epub 2021 Dec 3 doi: 10.1007/s00423-021-02387-3. PMID: 34860291Free PMC Article

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