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Sclerosing hepatic carcinoma

MedGen UID:
266088
•Concept ID:
C1266018
•
Neoplastic Process
Synonyms: Hepatocellular carcinoma, scirrhous; scirrhous hepatocellular cancer; Scirrhous Hepatocellular Carcinoma; scirrhous hepatocellular carcinoma; Sclerosing Hepatic Carcinoma; sclerosing hepatic carcinoma; Sclerosing Hepatocellular Carcinoma; sclerosing hepatocellular carcinoma
SNOMED CT: Sclerosing hepatic carcinoma (128646008); Hepatocellular carcinoma, scirrhous (128646008)
 
Monarch Initiative: MONDO:0003246

Definition

An uncommon type of hepatocelluar carcinoma, morphologically characterized by significant fibrosis around the sinusoid-like spaces and atrophy of the tumor trabeculae. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSclerosing hepatic carcinoma

Professional guidelines

PubMed

Imaging Features of Primary Sclerosing Cholangitis: From Diagnosis to Liver Transplant Follow-up.
Khoshpouri P, Habibabadi RR, Hazhirkarzar B, Ameli S, Ghadimi M, Ghasabeh MA, Menias CO, Kim A, Li Z, Kamel IR
Radiographics 2019 Nov-Dec;39(7):1938-1964. Epub 2019 Oct 18 doi: 10.1148/rg.2019180213. PMID: 31626561
Pathogenesis, diagnosis, and management of cholangiocarcinoma.
Rizvi S, Gores GJ
Gastroenterology 2013 Dec;145(6):1215-29. Epub 2013 Oct 15 doi: 10.1053/j.gastro.2013.10.013. PMID: 24140396Free PMC Article
Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management.
Eaton JE, Talwalkar JA, Lazaridis KN, Gores GJ, Lindor KD
Gastroenterology 2013 Sep;145(3):521-36. Epub 2013 Jul 1 doi: 10.1053/j.gastro.2013.06.052. PMID: 23827861Free PMC Article

Recent clinical studies

Etiology

CT-Guided Percutaneous Microwave Ablation of Sclerosing Hepatic Carcinoma.
Song H, Ding H, Zhu C
Can J Gastroenterol Hepatol 2020;2020:8881978. Epub 2020 Jul 15 doi: 10.1155/2020/8881978. PMID: 32733821Free PMC Article
Sclerosing hepatic carcinoma: relationship to hypercalcemia.
Omata M, Peters RL, Tatter D
Liver 1981 Mar;1(1):33-49. doi: 10.1111/j.1600-0676.1981.tb00020.x. PMID: 6294435

Diagnosis

Sclerosing hepatic carcinoma: helical CT features.
Kim SH, Lee WJ, Lim HK, Park CK
Abdom Imaging 2007 Nov;32(6):725-9. Epub 2007 Jan 3 doi: 10.1007/s00261-006-9174-0. PMID: 17203330
Sclerosing hepatic carcinoma in non-cirrhotic liver resembling metastatic adenocarcinoma.
Llovet JM, Miquel R
J Hepatol 1999 Jan;30(1):161. doi: 10.1016/s0168-8278(99)80021-x. PMID: 9927164
Sclerosing hepatic carcinoma: relationship to hypercalcemia.
Omata M, Peters RL, Tatter D
Liver 1981 Mar;1(1):33-49. doi: 10.1111/j.1600-0676.1981.tb00020.x. PMID: 6294435

Therapy

CT-Guided Percutaneous Microwave Ablation of Sclerosing Hepatic Carcinoma.
Song H, Ding H, Zhu C
Can J Gastroenterol Hepatol 2020;2020:8881978. Epub 2020 Jul 15 doi: 10.1155/2020/8881978. PMID: 32733821Free PMC Article

Prognosis

CT-Guided Percutaneous Microwave Ablation of Sclerosing Hepatic Carcinoma.
Song H, Ding H, Zhu C
Can J Gastroenterol Hepatol 2020;2020:8881978. Epub 2020 Jul 15 doi: 10.1155/2020/8881978. PMID: 32733821Free PMC Article
Sclerosing hepatic carcinoma: a report of a case treated with a transcatheter arterial embolization.
Ohtomo K, Furui S, Iio M, Kanamori H, Ishikawa T, Takaku F
Radiat Med 1984 Apr-Jun;2(2):104-7. PMID: 6522635

Clinical prediction guides

In situ demonstration of parathyroid hormone-related protein mRNA in sclerosing hepatic carcinoma.
Kitazawa R, Kitazawa S, Yoon S, Kasuga M, Maeda S
Virchows Arch 1999 Aug;435(2):137-42. doi: 10.1007/s004280050411. PMID: 10599313

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