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Chondroid lipoma

MedGen UID:
266104
•Concept ID:
C1266131
•
Neoplastic Process
Synonyms: Chondroid Lipoma; chondroid lipoma
SNOMED CT: Chondroid lipoma (404065000); Chondroid lipoma (128746001)
 
Monarch Initiative: MONDO:0000977

Definition

A rare benign adipose tissue neoplasm characterized by nests and cord of abundant univacuolated and multivacuolated lipoblasts and mature adipocytes in a prominent myxoid to hyalinized chondroid matrix admix. It predominantly affects females. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChondroid lipoma

Professional guidelines

PubMed

Cytogenetic and molecular genetic analyses of liposarcoma and its soft tissue simulators: recognition of new variants and differential diagnosis.
Meis-Kindblom JM, Sjögren H, Kindblom LG, Peydró-Mellquist A, Röijer E, Aman P, Stenman G
Virchows Arch 2001 Aug;439(2):141-51. doi: 10.1007/s004280100423. PMID: 11561754

Recent clinical studies

Etiology

A contemporary review of myxoid adipocytic tumors.
Creytens D
Semin Diagn Pathol 2019 Mar;36(2):129-141. Epub 2019 Feb 28 doi: 10.1053/j.semdp.2019.02.008. PMID: 30853315
Tumoral, quasitumoral and pseudotumoral lesions of the superficial and somatic soft tissue: new entities and new variants of old entities recorded during the last 25 years. Part XII: appendix.
Bisceglia M, Spagnolo D, Galliani C, Fisher C, Suster S, Kazakov DV, Cooper K, Michal M
Pathologica 2006 Aug;98(4):239-98. PMID: 17175794
Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses.
Gaskin CM, Helms CA
AJR Am J Roentgenol 2004 Mar;182(3):733-9. doi: 10.2214/ajr.182.3.1820733. PMID: 14975977
Lipomatous tumors.
Weiss SW
Monogr Pathol 1996;38:207-39. PMID: 8744279
Lipomatous tumours of soft tissues: an update.
Mentzel T, Fletcher CD
Virchows Arch 1995;427(4):353-63. doi: 10.1007/BF00199383. PMID: 8548119

Diagnosis

Characteristics of chondroid lipoma: A case report and literature review.
Huang C, Guo W, Qu W, Zhu Z, Li R
Medicine (Baltimore) 2019 May;98(19):e15587. doi: 10.1097/MD.0000000000015587. PMID: 31083243Free PMC Article
A contemporary review of myxoid adipocytic tumors.
Creytens D
Semin Diagn Pathol 2019 Mar;36(2):129-141. Epub 2019 Feb 28 doi: 10.1053/j.semdp.2019.02.008. PMID: 30853315
Chondroid lipoma: an update and review.
Thway K, Flora RS, Fisher C
Ann Diagn Pathol 2012 Jun;16(3):230-4. doi: 10.1016/j.anndiagpath.2012.01.002. PMID: 22607659
Ossifying chondroid lipoma.
Hoch B, Hermann G, Klein MJ, Abdelwahab IF
Skeletal Radiol 2008 May;37(5):475-80. Epub 2008 Feb 8 doi: 10.1007/s00256-007-0444-x. PMID: 18259746
Lipomatous tumors.
Weiss SW
Monogr Pathol 1996;38:207-39. PMID: 8744279

Prognosis

Chondroid lipoma--a case report.
Manna AK, Chattopadhyay A, Chowdhury K, Chowdhury MK, Dutta SK
Indian J Pathol Microbiol 2006 Jul;49(3):422-4. PMID: 17001908
Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses.
Gaskin CM, Helms CA
AJR Am J Roentgenol 2004 Mar;182(3):733-9. doi: 10.2214/ajr.182.3.1820733. PMID: 14975977
Cytogenetic and molecular genetic analyses of liposarcoma and its soft tissue simulators: recognition of new variants and differential diagnosis.
Meis-Kindblom JM, Sjögren H, Kindblom LG, Peydró-Mellquist A, Röijer E, Aman P, Stenman G
Virchows Arch 2001 Aug;439(2):141-51. doi: 10.1007/s004280100423. PMID: 11561754
Lipomatous tumors.
Weiss SW
Monogr Pathol 1996;38:207-39. PMID: 8744279

Clinical prediction guides

Chondroid lipoma: multimodality imaging in a 9-year-old female.
Tannenbaum M, Colucci PG, Baad M, Borczuk AC, Steigman SA, Kovanlikaya A
Skeletal Radiol 2020 Jan;49(1):161-169. Epub 2019 Jun 22 doi: 10.1007/s00256-019-03259-0. PMID: 31230114
Chondroid lipoma of the neck: a case report.
Katsuyama Y, Shirai T, Terauchi R, Tsuchida S, Mizoshiri N, Mori Y, Kubo T
BMC Res Notes 2018 Jun 28;11(1):415. doi: 10.1186/s13104-018-3523-2. PMID: 29954455Free PMC Article
Chondroid lipoma of the trunk: MRI appearance and pathologic correlation.
Boets A, Van Mieghem IM, Sciot R, Van Breuseghem I
Skeletal Radiol 2004 Nov;33(11):666-9. Epub 2004 May 5 doi: 10.1007/s00256-004-0774-x. PMID: 15133639
Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses.
Gaskin CM, Helms CA
AJR Am J Roentgenol 2004 Mar;182(3):733-9. doi: 10.2214/ajr.182.3.1820733. PMID: 14975977
Chondroid lipoma: an ultrastructural and immunohistochemical analysis with further observations regarding its differentiation.
Kindblom LG, Meis-Kindblom JM
Hum Pathol 1995 Jul;26(7):706-15. doi: 10.1016/0046-8177(95)90217-1. PMID: 7628841

Recent systematic reviews

Chondroid lipoma: multimodality imaging in a 9-year-old female.
Tannenbaum M, Colucci PG, Baad M, Borczuk AC, Steigman SA, Kovanlikaya A
Skeletal Radiol 2020 Jan;49(1):161-169. Epub 2019 Jun 22 doi: 10.1007/s00256-019-03259-0. PMID: 31230114

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