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Cervical basaloid carcinoma

MedGen UID:
267027
•Concept ID:
C1511063
•
Neoplastic Process
Synonyms: Cervical Basaloid Carcinoma; cervical basaloid carcinoma; Cervical Basaloid Squamous Cell Carcinoma; cervical basaloid squamous cell carcinoma
 
Monarch Initiative: MONDO:0004088

Definition

An aggressive variant of cervical squamous cell carcinoma characterized by the presence of nests of malignant basaloid squamous cells with scant amount of cytoplasm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCervical basaloid carcinoma

Professional guidelines

PubMed

How phenotype guides management of non-conventional squamous cell carcinomas of the larynx?
López F, Williams MD, Cardesa A, Hunt JL, Strojan P, Rinaldo A, Nixon IJ, Rodrigo JP, Saba NF, Mendenhall WM, Quer M, Suárez C, Ferlito A
Eur Arch Otorhinolaryngol 2017 Jul;274(7):2709-2726. Epub 2017 Mar 31 doi: 10.1007/s00405-017-4533-8. PMID: 28364287
Role of cytology in the diagnosis and management of HPV-associated head and neck carcinoma.
Krane JF
Acta Cytol 2013;57(2):117-26. Epub 2013 Feb 28 doi: 10.1159/000346715. PMID: 23406782
A reappraisal of "basaloid carcinoma" of the cervix, and the differential diagnosis of basaloid cervical neoplasms.
Grayson W, Cooper K
Adv Anat Pathol 2002 Sep;9(5):290-300. doi: 10.1097/00125480-200209000-00003. PMID: 12195218

Recent clinical studies

Etiology

Transoral laryngeal microsurgery for early-stage laryngeal basaloid squamous cell carcinoma.
Verro B, Saraniti C
BMJ Case Rep 2021 Dec 30;14(12) doi: 10.1136/bcr-2021-245746. PMID: 34969794Free PMC Article
Oral epithelial dysplasia: Recognition, grading and clinical significance.
Odell E, Kujan O, Warnakulasuriya S, Sloan P
Oral Dis 2021 Nov;27(8):1947-1976. Epub 2021 Sep 14 doi: 10.1111/odi.13993. PMID: 34418233
Comedo-like skin metastases in cervical carcinoma.
Kozubík E, Pribulová T, Rokos T, Kudela E, Slavik P, Biringer K
Neuro Endocrinol Lett 2021 Jul;42(3):157-159. PMID: 34279858
How phenotype guides management of non-conventional squamous cell carcinomas of the larynx?
López F, Williams MD, Cardesa A, Hunt JL, Strojan P, Rinaldo A, Nixon IJ, Rodrigo JP, Saba NF, Mendenhall WM, Quer M, Suárez C, Ferlito A
Eur Arch Otorhinolaryngol 2017 Jul;274(7):2709-2726. Epub 2017 Mar 31 doi: 10.1007/s00405-017-4533-8. PMID: 28364287
The role of cytology in the era of HPV-related head and neck carcinoma.
Roy-Chowdhuri S, Krishnamurthy S
Semin Diagn Pathol 2015 Jul;32(4):250-7. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.006. PMID: 25638437

Diagnosis

Oral epithelial dysplasia: Recognition, grading and clinical significance.
Odell E, Kujan O, Warnakulasuriya S, Sloan P
Oral Dis 2021 Nov;27(8):1947-1976. Epub 2021 Sep 14 doi: 10.1111/odi.13993. PMID: 34418233
Diagnostic traps awaiting the head/neck pathologist: "Cytoplasm-poor" neoplasms.
Wakely PE Jr
Ann Diagn Pathol 2019 Oct;42:78-86. Epub 2019 Jul 27 doi: 10.1016/j.anndiagpath.2019.07.005. PMID: 31382078
How phenotype guides management of non-conventional squamous cell carcinomas of the larynx?
López F, Williams MD, Cardesa A, Hunt JL, Strojan P, Rinaldo A, Nixon IJ, Rodrigo JP, Saba NF, Mendenhall WM, Quer M, Suárez C, Ferlito A
Eur Arch Otorhinolaryngol 2017 Jul;274(7):2709-2726. Epub 2017 Mar 31 doi: 10.1007/s00405-017-4533-8. PMID: 28364287
The role of cytology in the era of HPV-related head and neck carcinoma.
Roy-Chowdhuri S, Krishnamurthy S
Semin Diagn Pathol 2015 Jul;32(4):250-7. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.006. PMID: 25638437
Basaloid-squamous carcinoma of the palate.
Lovejoy HM, Matthews BL
Otolaryngol Head Neck Surg 1992 Feb;106(2):159-62. doi: 10.1177/019459989210600206. PMID: 1738547

Therapy

Systemic therapy in non-conventional cancers of the larynx.
Tan E, Mody MD, Saba NF
Oral Oncol 2018 Jul;82:61-68. Epub 2018 May 26 doi: 10.1016/j.oraloncology.2018.05.005. PMID: 29909903
Basaloid squamous cell carcinoma of the larynx--A systematic review.
Thankappan K
Auris Nasus Larynx 2012 Aug;39(4):397-401. Epub 2011 Aug 24 doi: 10.1016/j.anl.2011.07.018. PMID: 21868181
Recent data about the role of human papillomavirus (HPV) in oncogenesis of head and neck cancer.
Bădulescu F, Crişan A, Bădulescu A, Schenker M
Rom J Morphol Embryol 2010;51(3):437-40. PMID: 20809017
Papillary squamous cell carcinoma of the uterine cervix, high-risk human papilloma virus infection and p16(INK4a) expression: a case report.
Eleutério J Jr, Giraldo PC, Cavalcante DI, Gonçalves AK, Eleutério RM, Giraldo HP
Acta Cytol 2009 Mar-Apr;53(2):188-90. doi: 10.1159/000325122. PMID: 19365973
The histomorphologic spectrum of endocervical (Müllerian) adenocarcinoma--a potential prognostic indicator.
Parker JC Jr, Nagell JR Jr, Bissig T
J Surg Oncol 1977;9(3):267-75. doi: 10.1002/jso.2930090309. PMID: 195142

Prognosis

Case Report: Basaloid Squamous Cell Carcinoma of the Tongue: A Case Report.
Khan SJA, Gawande M, Hande A, Patil S, Sonone A, Pakhale A
F1000Res 2023;12:1008. Epub 2024 Mar 26 doi: 10.12688/f1000research.134826.2. PMID: 38515860Free PMC Article
Oral epithelial dysplasia: Recognition, grading and clinical significance.
Odell E, Kujan O, Warnakulasuriya S, Sloan P
Oral Dis 2021 Nov;27(8):1947-1976. Epub 2021 Sep 14 doi: 10.1111/odi.13993. PMID: 34418233
The role of cytology in the era of HPV-related head and neck carcinoma.
Roy-Chowdhuri S, Krishnamurthy S
Semin Diagn Pathol 2015 Jul;32(4):250-7. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.006. PMID: 25638437
Adenoid cystic carcinoma: clinical and molecular features.
Moskaluk CA
Head Neck Pathol 2013 Mar;7(1):17-22. Epub 2013 Mar 5 doi: 10.1007/s12105-013-0426-3. PMID: 23463073Free PMC Article
Basaloid squamous cell carcinoma of the larynx--A systematic review.
Thankappan K
Auris Nasus Larynx 2012 Aug;39(4):397-401. Epub 2011 Aug 24 doi: 10.1016/j.anl.2011.07.018. PMID: 21868181

Clinical prediction guides

Oral epithelial dysplasia: Recognition, grading and clinical significance.
Odell E, Kujan O, Warnakulasuriya S, Sloan P
Oral Dis 2021 Nov;27(8):1947-1976. Epub 2021 Sep 14 doi: 10.1111/odi.13993. PMID: 34418233
Penile Analogue of Stratified Mucin-Producing Intraepithelial Lesion of the Cervix: The First Described Case. A Diagnostic Pitfall.
Michal M, Michal M, Miesbauerova M, Hercogova J, Skopalikova B, Kazakov DV
Am J Dermatopathol 2016 May;38(5):e64-7. doi: 10.1097/DAD.0000000000000462. PMID: 27097242
Cytologic mimics of non-Hodgkin lymphoma in the head and neck.
Ylagan LR
Semin Diagn Pathol 2015 Jul;32(4):296-304. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2014.12.011. PMID: 25753530
The role of cytology in the era of HPV-related head and neck carcinoma.
Roy-Chowdhuri S, Krishnamurthy S
Semin Diagn Pathol 2015 Jul;32(4):250-7. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.006. PMID: 25638437
The occasional role of low-risk human papillomaviruses 6, 11, 42, 44, and 70 in anogenital carcinoma defined by laser capture microdissection/PCR methodology: results from a global study.
Guimerà N, Lloveras B, Lindeman J, Alemany L, van de Sandt M, Alejo M, Hernandez-Suarez G, Bravo IG, Molijn A, Jenkins D, Cubilla A, Muñoz N, de Sanjose S, Bosch FX, Quint W; RIS HPV TTHPV VVAPO study groups
Am J Surg Pathol 2013 Sep;37(9):1299-310. doi: 10.1097/PAS.0b013e31828b6be4. PMID: 24076770

Recent systematic reviews

Effectiveness of Nasolacrimal SCC Treatments and Promising Role of Chemo-Induction: A Case Report and Systematic Review.
Alsavaf MB, Abouammo MD, Bhuskute GS, Sun S, Issa M, Seim NB, VanKoevering KK, Bhateja P, Bonomi M, Carrau RL
Laryngoscope 2024 Sep;134(9):3892-3902. Epub 2024 Apr 23 doi: 10.1002/lary.31426. PMID: 38651346
Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma-An Even Broader Tumor Entity?
Zupancic M, Näsman A
Viruses 2021 Sep 17;13(9) doi: 10.3390/v13091861. PMID: 34578442Free PMC Article
Comparative Analysis Between Dentinogenic Ghost Cell Tumor and Ghost Cell Odontogenic Carcinoma: A Systematic Review.
de Souza Vieira G, de Pinho Montovani P, Rozza-de-Menezes RE, Cunha KSG, Conde DC
Head Neck Pathol 2021 Dec;15(4):1265-1283. Epub 2021 Jun 14 doi: 10.1007/s12105-021-01347-z. PMID: 34128137Free PMC Article
Basaloid squamous cell carcinoma of the larynx--A systematic review.
Thankappan K
Auris Nasus Larynx 2012 Aug;39(4):397-401. Epub 2011 Aug 24 doi: 10.1016/j.anl.2011.07.018. PMID: 21868181

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