U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Base-Base Mismatch

MedGen UID:
267029
Concept ID:
C1511065
Cell or Molecular Dysfunction

Definition

Base-Base Mismatch results from mutagenic factors that induce chemical modification of DNA bases so that pairing between specific bases on complementary DNA strands is eliminated causing mispairing. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBase-Base Mismatch

Professional guidelines

PubMed

Pietrantonio F, Randon G, Romagnoli D, Di Donato S, Benelli M, de Braud F
Cancer Treat Rev 2020 Jan;82:101935. Epub 2019 Nov 28 doi: 10.1016/j.ctrv.2019.101935. PMID: 31821983
Lee DU, Huang W, Rittenhouse KD, Jessen B
J Ocul Pharmacol Ther 2012 Jun;28(3):222-30. Epub 2012 Feb 3 doi: 10.1089/jop.2011.0116. PMID: 22304497
King BP, Leathart JB, Mutch E, Williams FM, Daly AK
Br J Clin Pharmacol 2003 Jun;55(6):625-9. doi: 10.1046/j.1365-2125.2003.01798.x. PMID: 12814460Free PMC Article

Recent clinical studies

Diagnosis

Nohmi T, Matsumoto K
Environ Mol Mutagen 2020 Jan;61(1):193-199. Epub 2019 Jul 25 doi: 10.1002/em.22315. PMID: 31294882
Pinto RM, Dragileva E, Kirby A, Lloret A, Lopez E, St Claire J, Panigrahi GB, Hou C, Holloway K, Gillis T, Guide JR, Cohen PE, Li GM, Pearson CE, Daly MJ, Wheeler VC
PLoS Genet 2013 Oct;9(10):e1003930. Epub 2013 Oct 31 doi: 10.1371/journal.pgen.1003930. PMID: 24204323Free PMC Article
Pepponi R, Graziani G, Falcinelli S, Vernole P, Levati L, Lacal PM, Pagani E, Bonmassar E, Jiricny J, D'Atri S
Carcinogenesis 2001 Aug;22(8):1131-7. doi: 10.1093/carcin/22.8.1131. PMID: 11470740

Clinical prediction guides

Nohmi T, Matsumoto K
Environ Mol Mutagen 2020 Jan;61(1):193-199. Epub 2019 Jul 25 doi: 10.1002/em.22315. PMID: 31294882
Huang YM, Chen SU, Goodman SD, Wu SH, Kao JT, Lee CN, Cheng WC, Tsai KS, Fang WH
J Biol Chem 2004 Jul 16;279(29):30228-35. Epub 2004 May 18 doi: 10.1074/jbc.M401675200. PMID: 15151992

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...