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DNA Adduction

MedGen UID:
268315
Concept ID:
C1511660
Cell or Molecular Dysfunction
Synonym: DNA Adduct Formation

Definition

DNA Adduction involves formation of a covalent bond between a molecule and the DNA macromolecule. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDNA Adduction

Professional guidelines

PubMed

McQuade RM, Stojanovska V, Bornstein JC, Nurgali K
Curr Med Chem 2017;24(15):1537-1557. doi: 10.2174/0929867324666170111152436. PMID: 28079003
Xu Y, Cui B, Ran R, Liu Y, Chen H, Kai G, Shi J
Food Chem Toxicol 2014 Jul;69:1-12. Epub 2014 Apr 5 doi: 10.1016/j.fct.2014.03.037. PMID: 24713263
Yongvanit P, Pinlaor S, Loilome W
J Hepatobiliary Pancreat Sci 2014 May;21(5):309-15. Epub 2014 Jan 10 doi: 10.1002/jhbp.63. PMID: 24408859

Recent clinical studies

Etiology

Krawic C, Zhitkovich A
Adv Pharmacol 2023;96:25-46. Epub 2022 Aug 26 doi: 10.1016/bs.apha.2022.07.003. PMID: 36858775Free PMC Article
Caliri AW, Tommasi S, Besaratinia A
Mutat Res Rev Mutat Res 2021 Jan-Jun;787:108365. Epub 2021 Jan 11 doi: 10.1016/j.mrrev.2021.108365. PMID: 34083039Free PMC Article
Pfohl-Leszkowicz A, Manderville RA
Chem Res Toxicol 2012 Feb 20;25(2):252-62. Epub 2011 Nov 16 doi: 10.1021/tx200430f. PMID: 22054007
Pfohl-Leszkowicz A, Manderville RA
Mol Nutr Food Res 2007 Jan;51(1):61-99. doi: 10.1002/mnfr.200600137. PMID: 17195275
McDonald TA, Komulainen H
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2005;23(2):163-214. doi: 10.1080/10590500500234988. PMID: 16291527

Diagnosis

Madeen E, Siddens LK, Uesugi S, McQuistan T, Corley RA, Smith J, Waters KM, Tilton SC, Anderson KA, Ognibene T, Turteltaub K, Williams DE
Toxicol Appl Pharmacol 2019 Feb 1;364:97-105. Epub 2018 Dec 21 doi: 10.1016/j.taap.2018.12.010. PMID: 30582946Free PMC Article
Wang S, Scharadin TM, Zimmermann M, Malfatti MA, Turteltaub KW, de Vere White R, Pan CX, Henderson PT
Chem Res Toxicol 2018 Dec 17;31(12):1293-1304. Epub 2018 Nov 19 doi: 10.1021/acs.chemrestox.8b00170. PMID: 30381944Free PMC Article
Pfohl-Leszkowicz A, Manderville RA
Mol Nutr Food Res 2007 Jan;51(1):61-99. doi: 10.1002/mnfr.200600137. PMID: 17195275
Peluso M, Neri M, Margarino G, Mereu C, Munnia A, Ceppi M, Buratti M, Felletti R, Stea F, Quaglia R, Puntoni R, Taioli E, Garte S, Bonassi S
Carcinogenesis 2004 Dec;25(12):2459-65. Epub 2004 Aug 19 doi: 10.1093/carcin/bgh259. PMID: 15319297
Turteltaub KW, Vogel JS, Frantz C, Felton JS, McManus M
Princess Takamatsu Symp 1995;23:93-102. PMID: 8844800

Therapy

Caliri AW, Tommasi S, Besaratinia A
Mutat Res Rev Mutat Res 2021 Jan-Jun;787:108365. Epub 2021 Jan 11 doi: 10.1016/j.mrrev.2021.108365. PMID: 34083039Free PMC Article
He Y, Shi M, Wu X, Ma J, Ng KT, Xia Q, Zhu L, Fu PP, Man K, Tsui SK, Lin G
Hepatology 2021 Jul;74(1):264-280. Epub 2021 Jun 15 doi: 10.1002/hep.31723. PMID: 33462832
Sidorenko VS
Adv Exp Med Biol 2020;1241:139-166. doi: 10.1007/978-3-030-41283-8_9. PMID: 32383120
Besaratinia A, Tommasi S
FASEB J 2013 Jun;27(6):2090-100. Epub 2013 Feb 28 doi: 10.1096/fj.12-227074. PMID: 23449930
De Flora S, Cesarone CF, Balansky RM, Albini A, D'Agostini F, Bennicelli C, Bagnasco M, Camoirano A, Scatolini L, Rovida A
J Cell Biochem Suppl 1995;22:33-41. doi: 10.1002/jcb.240590806. PMID: 8538208

Prognosis

Chen C, Zhang D, Yuan A, Shen J, Wang L, Wang SL
Sci Total Environ 2022 Oct 15;843:157052. Epub 2022 Jul 1 doi: 10.1016/j.scitotenv.2022.157052. PMID: 35787903
Wang S, Scharadin TM, Zimmermann M, Malfatti MA, Turteltaub KW, de Vere White R, Pan CX, Henderson PT
Chem Res Toxicol 2018 Dec 17;31(12):1293-1304. Epub 2018 Nov 19 doi: 10.1021/acs.chemrestox.8b00170. PMID: 30381944Free PMC Article
Besaratinia A, Tommasi S
FASEB J 2013 Jun;27(6):2090-100. Epub 2013 Feb 28 doi: 10.1096/fj.12-227074. PMID: 23449930
Colvin ME, Hatch FT, Felton JS
Mutat Res 1998 May 25;400(1-2):479-92. doi: 10.1016/s0027-5107(98)00073-6. PMID: 9685706
Mariën K, Mathews K, van Holde K, Bailey G
J Biol Chem 1989 Aug 5;264(22):13226-32. PMID: 2502547

Clinical prediction guides

Chen C, Zhang D, Yuan A, Shen J, Wang L, Wang SL
Sci Total Environ 2022 Oct 15;843:157052. Epub 2022 Jul 1 doi: 10.1016/j.scitotenv.2022.157052. PMID: 35787903
Wang S, Scharadin TM, Zimmermann M, Malfatti MA, Turteltaub KW, de Vere White R, Pan CX, Henderson PT
Chem Res Toxicol 2018 Dec 17;31(12):1293-1304. Epub 2018 Nov 19 doi: 10.1021/acs.chemrestox.8b00170. PMID: 30381944Free PMC Article
Pfohl-Leszkowicz A, Manderville RA
Mol Nutr Food Res 2007 Jan;51(1):61-99. doi: 10.1002/mnfr.200600137. PMID: 17195275
McDonald TA, Komulainen H
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2005;23(2):163-214. doi: 10.1080/10590500500234988. PMID: 16291527
Colvin ME, Hatch FT, Felton JS
Mutat Res 1998 May 25;400(1-2):479-92. doi: 10.1016/s0027-5107(98)00073-6. PMID: 9685706

Supplemental Content

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    Practice guidelines

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