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Ovarian Mucinous Cystic Tumor with Mural Nodules

MedGen UID:
269341
Concept ID:
C1513716
Neoplastic Process

Definition

A mucinous cystic tumor of the ovary characterized by the presence of one or more well circumscribed solid nodules in the wall of the cysts (mural nodules) that protrude into the lumen. The mural nodules may be benign (sarcoma-like) or malignant. The malignant mural nodules histologically are anaplastic carcinomas, carcinosarcomas, or sarcomas. The clinical course depends on the histology of the mural nodules. The prognosis of mucinous cystic tumors with benign mural nodules is the same as the corresponding types of mucinous cystic tumors without the mural nodules. Mucinous cystic tumors with malignant mural nodules may follow a malignant clinical course. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian Mucinous Cystic Tumor with Mural Nodules

Professional guidelines

Recent clinical studies

Etiology

Li D, Kiryu S, Wang F
J Pediatr Adolesc Gynecol 2022 Jun;35(3):346-352. Epub 2021 Oct 31 doi: 10.1016/j.jpag.2021.10.008. PMID: 34728347
Kaga T, Kato H, Hatano Y, Kawaguchi M, Furui T, Morishige KI, Matsuo M
Eur J Radiol 2020 Nov;132:109281. Epub 2020 Sep 12 doi: 10.1016/j.ejrad.2020.109281. PMID: 32961452
Keane MG, Shamali A, Nilsson LN, Antila A, Millastre Bocos J, Marijinissen Van Zanten M, Verdejo Gil C, Maisonneuve P, Vaalavuo Y, Hoskins T, Robinson S, Ceyhan GO, Abu Hilal M, Pereira SP, Laukkarinen J, Del Chiaro M
Br J Surg 2018 Mar;105(4):439-446. doi: 10.1002/bjs.10787. PMID: 29488646
Gil E, Choi SH, Choi DW, Heo JS, Kim MJ
ANZ J Surg 2013 Dec;83(12):985-90. Epub 2012 Oct 16 doi: 10.1111/j.1445-2197.2012.06295.x. PMID: 23072713
Bagué S, Rodríguez IM, Prat J
Am J Surg Pathol 2002 Nov;26(11):1467-76. doi: 10.1097/00000478-200211000-00009. PMID: 12409723

Diagnosis

Huang M, Lv Q, Xie J
J Ovarian Res 2022 Jul 14;15(1):83. doi: 10.1186/s13048-022-01010-3. PMID: 35836292Free PMC Article
Shetty D, Bhalekar S, Rao S, Mukharji S, Rao R
Int J Gynecol Pathol 2022 Jul 1;41(4):343-348. Epub 2021 Aug 11 doi: 10.1097/PGP.0000000000000816. PMID: 34380973
Yang S, Wang L, Sun K
Medicine (Baltimore) 2019 Jan;98(3):e14066. doi: 10.1097/MD.0000000000014066. PMID: 30653119Free PMC Article
Gil E, Choi SH, Choi DW, Heo JS, Kim MJ
ANZ J Surg 2013 Dec;83(12):985-90. Epub 2012 Oct 16 doi: 10.1111/j.1445-2197.2012.06295.x. PMID: 23072713
Chang JS, Chua CC, Lee CC
Ann Saudi Med 2012 Jul-Aug;32(4):415-20. doi: 10.5144/0256-4947.2012.415. PMID: 22705615Free PMC Article

Therapy

Chaudet K, Kem M, Lerwill M, Young RH, Mino-Kenudson M, Agaimy A, McCluggage WG, Oliva E
Histopathology 2020 Aug;77(2):231-239. Epub 2020 Jul 2 doi: 10.1111/his.14110. PMID: 32268438
Chang JS, Chua CC, Lee CC
Ann Saudi Med 2012 Jul-Aug;32(4):415-20. doi: 10.5144/0256-4947.2012.415. PMID: 22705615Free PMC Article
Kaku M, Ohara N, Seima Y, Imanishi K, Tomura N, Kobayashi A, Yamasaki M, Hirata Y, Murao S
Arch Gynecol Obstet 2004 Dec;270(4):302-6. Epub 2003 Oct 10 doi: 10.1007/s00404-003-0550-5. PMID: 14551796
Mizuno K, Hirata S, Kasai T, Yasumizu T, Kato J
J Obstet Gynaecol Res 1996 Oct;22(5):461-5. doi: 10.1111/j.1447-0756.1996.tb01058.x. PMID: 8987329
Tsuruchi N, Kaku T, Kinoshita H, Amada S, Saito T, Kamura T, Tsukamoto N, Nakano H
Gynecol Oncol 1993 Aug;50(2):259-63. doi: 10.1006/gyno.1993.1204. PMID: 8375741

Prognosis

Huang M, Lv Q, Xie J
J Ovarian Res 2022 Jul 14;15(1):83. doi: 10.1186/s13048-022-01010-3. PMID: 35836292Free PMC Article
Shetty D, Bhalekar S, Rao S, Mukharji S, Rao R
Int J Gynecol Pathol 2022 Jul 1;41(4):343-348. Epub 2021 Aug 11 doi: 10.1097/PGP.0000000000000816. PMID: 34380973
Gil E, Choi SH, Choi DW, Heo JS, Kim MJ
ANZ J Surg 2013 Dec;83(12):985-90. Epub 2012 Oct 16 doi: 10.1111/j.1445-2197.2012.06295.x. PMID: 23072713
Hart WR
Int J Gynecol Pathol 2005 Jan;24(1):4-25. PMID: 15626914
Chan YF, Ho HC, Yau SM, Ma L
Gynecol Oncol 1989 Oct;35(1):112-9. doi: 10.1016/0090-8258(89)90024-3. PMID: 2477315

Clinical prediction guides

Ohya A, Fujinaga Y
Jpn J Radiol 2022 Dec;40(12):1213-1234. Epub 2022 Aug 2 doi: 10.1007/s11604-022-01321-x. PMID: 35916971Free PMC Article
Chapel DB, Lee EK, Da Silva AFL, Teschan N, Feltmate C, Matulonis UA, Crum CP, Sholl LM, Konstantinopoulos PA, Nucci MR
Mod Pathol 2021 Mar;34(3):613-626. Epub 2020 Aug 5 doi: 10.1038/s41379-020-0642-9. PMID: 32759977
Kaga T, Kato H, Hatano Y, Kawaguchi M, Furui T, Morishige KI, Matsuo M
Eur J Radiol 2020 Nov;132:109281. Epub 2020 Sep 12 doi: 10.1016/j.ejrad.2020.109281. PMID: 32961452
Keane MG, Shamali A, Nilsson LN, Antila A, Millastre Bocos J, Marijinissen Van Zanten M, Verdejo Gil C, Maisonneuve P, Vaalavuo Y, Hoskins T, Robinson S, Ceyhan GO, Abu Hilal M, Pereira SP, Laukkarinen J, Del Chiaro M
Br J Surg 2018 Mar;105(4):439-446. doi: 10.1002/bjs.10787. PMID: 29488646
Mesbah Ardakani N, Giardina T, Amanuel B, Stewart CJ
Am J Surg Pathol 2017 Sep;41(9):1261-1266. doi: 10.1097/PAS.0000000000000875. PMID: 28498287

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