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Testis polyembryoma

MedGen UID:
271324
•Concept ID:
C1514200
•
Neoplastic Process
Synonyms: Polyembryoma of Testis; polyembryoma of testis; Polyembryoma of the Testis; polyembryoma of the testis; Testicular Polyembryoma; testicular polyembryoma; testis polyembryoma
 
Monarch Initiative: MONDO:0004442

Definition

A rare malignant germ cell tumor that arises from the testis and is characterized by the presence of embryoid bodies. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTestis polyembryoma

Professional guidelines

PubMed

Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467

Recent clinical studies

Etiology

Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467
Germ cell neoplasms of the testis.
Ulbright TM
Am J Surg Pathol 1993 Nov;17(11):1075-91. doi: 10.1097/00000478-199311000-00001. PMID: 8214253

Diagnosis

FoxA2 is a reliable marker for the diagnosis of yolk sac tumour postpubertal-type.
Ricci C, Ambrosi F, Franceschini T, Giunchi F, Di Filippo G, Franchini E, Massari F, Mollica V, Tateo V, Bianchi FM, Colecchia M, Acosta AM, Fiorentino M
Histopathology 2023 Sep;83(3):465-476. Epub 2023 Jun 14 doi: 10.1111/his.14968. PMID: 37317674
Polyembryoma of the testis: a report of two cases dominant within mixed germ cell tumors and review of gonadal polyembryomas.
Stall JN, Young RH
Mod Pathol 2017 Jul;30(7):908-918. Epub 2017 Apr 21 doi: 10.1038/modpathol.2017.25. PMID: 28429716
Testicular tumors--some new and a few perennial problems.
Young RH
Arch Pathol Lab Med 2008 Apr;132(4):548-64. doi: 10.5858/2008-132-548-TTNAAF. PMID: 18384207
Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467
Polyembryoma of testis.
Cornet A, Bultinck J, Declercq G
Acta Urol Belg 1985;53(1):107-14. PMID: 2986435

Therapy

Diffuse embryoma of the testis. An immunohistochemical study of two cases.
de Peralta-Venturina MN, Ro JY, Ordónez NG, Ayala AG
Am J Clin Pathol 1994 Oct;102(4):402-5. doi: 10.1093/ajcp/102.4.402. PMID: 7524298

Prognosis

Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467

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