U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Prostate Stromal Tumor of Uncertain Malignant Potential

MedGen UID:
271404
Concept ID:
C1514517
Neoplastic Process
Synonyms: Prostate Stromal Proliferation of Uncertain Malignant Potential; Prostatic Stromal Tumor of Uncertain Malignant Potential

Definition

A neoplastic lesion that arises from the prostate gland stroma. Morphologic characteristics include hypercellular stroma with scattered atypical cells, prominent overgrowth of the prostatic stroma, or changes resembling benign phyllodes tumor. The majority of cases do not have an aggressive clinical course. A minority of cases however, may progress to stromal sarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProstate Stromal Tumor of Uncertain Malignant Potential

Professional guidelines

PubMed

Li Y, Mongan J, Behr SC, Sud S, Coakley FV, Simko J, Westphalen AC
Radiographics 2016 Jul-Aug;36(4):1055-75. Epub 2016 Jun 17 doi: 10.1148/rg.2016150226. PMID: 27315446

Recent clinical studies

Etiology

Liu Y, Wu J, Shen Q, Li D, He Z, Zhou L, Xiao J
J Med Imaging Radiat Oncol 2022 Dec;66(8):1065-1072. Epub 2022 Apr 26 doi: 10.1111/1754-9485.13414. PMID: 35470966
Shen Q, Zhou Z, Liu Z, Hu S, Lin Z, Li S, Li S, Song H, Chen Y, Meng Y, Wang Y, Fan Y, Li X, Xiao Y, He Q, Jin J, Zhang Q, Yu W
Urol Int 2021;105(3-4):206-214. Epub 2020 Nov 20 doi: 10.1159/000508763. PMID: 33221793
Xu Y, Li Z, Shi J, Fu Y, Zhu L, Fan X, Foo WC
Virchows Arch 2021 Apr;478(4):619-626. Epub 2020 Aug 20 doi: 10.1007/s00428-020-02909-2. PMID: 32820389
Mokhtari M, Homayoun M, Yazdan Panah S
Arch Iran Med 2016 Jul;19(7):488-90. PMID: 27362242
Gaudin PB, Rosai J, Epstein JI
Am J Surg Pathol 1998 Feb;22(2):148-62. doi: 10.1097/00000478-199802000-00002. PMID: 9500215

Diagnosis

Bostwick DG, Egevad L
Pathology 2021 Jan;53(1):12-25. Epub 2020 Nov 13 doi: 10.1016/j.pathol.2020.09.017. PMID: 33190920
McKenney JK
Mod Pathol 2018 Jan;31(S1):S133-142. doi: 10.1038/modpathol.2017.155. PMID: 29297486
Li Y, Mongan J, Behr SC, Sud S, Coakley FV, Simko J, Westphalen AC
Radiographics 2016 Jul-Aug;36(4):1055-75. Epub 2016 Jun 17 doi: 10.1148/rg.2016150226. PMID: 27315446
Murer LM, Talmon GA
Arch Pathol Lab Med 2014 Nov;138(11):1542-5. doi: 10.5858/arpa.2013-0212-RS. PMID: 25357117
Tavora F, Kryvenko ON, Epstein JI
Pathology 2013 Feb;45(2):104-15. doi: 10.1097/PAT.0b013e32835c768b. PMID: 23250042

Therapy

Heymach JV, Shackleford TJ, Tran HT, Yoo SY, Do KA, Wergin M, Saintigny P, Vollmer RT, Polascik TJ, Snyder DC, Ruffin MT 4th, Yan S, Dewhirst M, Kunnumakkara AB, Aggarwal BB, Demark-Wahnefried W
Cancer Prev Res (Phila) 2011 Oct;4(10):1590-8. Epub 2011 Jul 15 doi: 10.1158/1940-6207.CAPR-10-0136. PMID: 21764858Free PMC Article

Prognosis

Liu Y, Wu J, Shen Q, Li D, He Z, Zhou L, Xiao J
J Med Imaging Radiat Oncol 2022 Dec;66(8):1065-1072. Epub 2022 Apr 26 doi: 10.1111/1754-9485.13414. PMID: 35470966
Marcal LP, Surabhi VR, Ramani NS, Katabathina VS, Paspulati RM, Prasad SR
Radiographics 2022 Mar-Apr;42(2):417-432. Epub 2022 Jan 14 doi: 10.1148/rg.210084. PMID: 35030067
Shen Q, Zhou Z, Liu Z, Hu S, Lin Z, Li S, Li S, Song H, Chen Y, Meng Y, Wang Y, Fan Y, Li X, Xiao Y, He Q, Jin J, Zhang Q, Yu W
Urol Int 2021;105(3-4):206-214. Epub 2020 Nov 20 doi: 10.1159/000508763. PMID: 33221793
Murer LM, Talmon GA
Arch Pathol Lab Med 2014 Nov;138(11):1542-5. doi: 10.5858/arpa.2013-0212-RS. PMID: 25357117
Tavora F, Kryvenko ON, Epstein JI
Pathology 2013 Feb;45(2):104-15. doi: 10.1097/PAT.0b013e32835c768b. PMID: 23250042

Clinical prediction guides

Liu Y, Wu J, Shen Q, Li D, He Z, Zhou L, Xiao J
J Med Imaging Radiat Oncol 2022 Dec;66(8):1065-1072. Epub 2022 Apr 26 doi: 10.1111/1754-9485.13414. PMID: 35470966
Greenland NY, Zhang L, Cowan JE, Carroll PR, Stohr BA, Simko JP
J Urol 2019 Jul;202(1):90-95. Epub 2019 Jun 7 doi: 10.1097/JU.0000000000000175. PMID: 30810466
Ronchi A, La Mantia E, Gigantino V, Perdonà S, De Sio M, Facchini G, Franco R, De Chiara A
Diagn Pathol 2017 Jul 7;12(1):50. doi: 10.1186/s13000-017-0640-5. PMID: 28687087Free PMC Article
Sadimin ET, Epstein JI
Hum Pathol 2016 Jun;52:68-73. Epub 2016 Feb 1 doi: 10.1016/j.humpath.2016.01.002. PMID: 26980017
Reikie BA, Yilmaz A, Medlicott S, Trpkov K
Adv Anat Pathol 2015 Mar;22(2):113-20. doi: 10.1097/PAP.0000000000000057. PMID: 25664946

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...