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Disorder of male genital organ

MedGen UID:: 42195
•Concept ID:: C0017412
•: Disease or Syndrome

Synonyms:	Disease, Male Genital; Diseases, Male Genital; Genital Disease, Male; Genital Diseases, Male; Male Genital Disease; Male Genital Diseases
SNOMED CT:	Male genital organ disease (64557000); Disorder of male genital organ (64557000)

Definition

Pathological processes involving the male reproductive tract (GENITALIA, MALE). [from MeSH]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVDisorder of male genital organ

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Disorder of the genitourinary system
        Diseases, Genital
        Disorder of male genital organ
        Disorder of testis
        Cryptorchidism
        Bilateral cryptorchidism
        Unilateral cryptorchidism
        Orchitis
        Non-specific granulomatous orchitis
        Testicular neoplasm
        Benign neoplasm of testis
        Childhood testicular neoplasm
        Germ cell tumor of testis
        Juvenile type testicular granulosa cell tumor
        Malignant tumor of testis
        Sertoli cell neoplasm
        Sertoli-Leydig cell tumor
        Testicular adrenal rest tumor
        Testicular Brenner tumor
        Testicular gonadoblastoma
        Testicular Mixed Germ Cell-Sex Cord-Stromal Tumor, Unclassified
        Testicular sex cord-stromal neoplasm
        Testicular teratoma
        Testicular Non-Neoplastic Disorder
        Ascending Testicle
        Retractile testis
        Testicular atrophy
        Testicular Hypotrophy
        Testicular infarct
        Testicular torsion
        Dyspareunia
        Epididymitis
        Erectile dysfunction
        Autonomic erectile dysfunction
        Impotence
        Priapism
        Vasculogenic impotence
        Fournier gangrene
        Genital herpes
        Hemospermia
        Hydrocele testis
        Congenital hydrocele
        Encysted hydrocele of the cord
        Infantile hydrocele
        Vaginal hydrocele
        Infection, Reproductive Tract
        Male genital tuberculosis
        Male hematocele
        Male infertility
        Abnormal sperm morphology
        Abnormal sperm axoneme morphology
        Abnormal sperm head morphology
        Abnormal sperm mid-piece morphology
        Abnormal sperm neck morphology
        Abnormal sperm tail morphology
        Excess residual spermatozoal cytoplasm
        Aspermia
        Azoospermia
        Non-obstructive azoospermia
        Obstructive azoospermia
        Pretesticular azoospermia
        Congenital absence of germinal epithelium of testes
        Oligozoospermia
        Cryptozoospermia
        Extreme oligozoospermia
        Mild oligozoospermia
        Moderate oligozoospermia
        Severe oligozoospermia
        Reduced sperm motility
        Male reproductive system neoplasm
        Benign male reproductive system neoplasm
        Benign neoplasm of epididymis
        Benign neoplasm of penis
        Benign neoplasm of prostate
        Benign Seminal Vesicle Neoplasm
        Paratesticular Adenomatoid Tumor
        Paratesticular Cellular Angiofibroma
        Paratesticular Deep (Aggressive) Angiomyxoma
        Paratesticular Hemangioma
        Paratesticular Leiomyoma
        Paratesticular lipoma
        Paratesticular Mammary-Type Myofibroblastoma
        Paratesticular Rhabdomyoma
        Paratesticular Schwannoma
        Rete testis adenoma
        Male Reproductive System Precancerous Condition
        Penile Intraepithelial Neoplasia
        Prostate intraepithelial neoplasia
        Prostate Stromal Tumor of Uncertain Malignant Potential
        Malignant Male Reproductive System Neoplasm
        Epididymis cancer
        Male Reproductive System Carcinoma
        Malignant Seminal Vesicle Neoplasm
        Malignant tumor of prostate
        Paratesticular Leiomyosarcoma
        Paratesticular Liposarcoma
        Paratesticular Malignant Mesothelioma
        Paratesticular Rhabdomyosarcoma
        Paratesticular Squamous Cell Carcinoma
        Paratesticular Wilms Tumor
        Penile cancer
        Recurrent Malignant Male Reproductive System Neoplasm
        Refractory Malignant Male Reproductive System Neoplasm
        Spermatic cord cancer
        Neoplasm of the male external genitalia
        Neoplasm of the penis
        Neoplasm of the scrotum
        Paratesticular Neoplasm
        Epididymal neoplasm
        Paratesticular Paraganglioma
        Paratesticular Soft Tissue Neoplasm
        Rete testis neoplasm
        Seminal vesicle tumor
        Prostate neoplasm
        Atypical Small Acinar Proliferation of the Prostate Gland
        Prostate neuroendocrine neoplasm
        Prostate phyllodes tumor
        Prostate Soft Tissue Neoplasm
        Prostatic Neoplasms, Castration-Resistant
        Penile disorder
        Balanitis
        Balanitis xerotica obliterans
        Leukoplakia of penis
        Hypospadias
        Coronal hypospadias
        Glandular hypospadias
        Midshaft hypospadias
        Penile hypospadias
        Penoscrotal hypospadias
        Perineal hypospadias
        Scrotal hypospadias
        Induratio penis plastica
        Penile Non-Neoplastic Disorder
        Paraphimosis
        Penile Chordee
        Tight foreskin
        Vascular disorder of penis
        Penile Angiosarcoma
        Penile Epithelioid Hemangioendothelioma
        Penile Hemangioma
        Penile Kaposi Sarcoma
        Penile Lymphangioma
        Premature ejaculation
        Prostate disorder
        Hyperplasia of prostate
        Proliferative Inflammatory Atrophy
        Prostate Non-Neoplastic Disorder
        Enlarged Prostate with Lower Urinary Tract Symptoms
        Prostatic Infection
        Prostatitis
        Spermatocele
        Varicocele

Professional guidelines

PubMed

EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.

Mottet N, van den Bergh RCN, Briers E, Van den Broeck T, Cumberbatch MG, De Santis M, Fanti S, Fossati N, Gandaglia G, Gillessen S, Grivas N, Grummet J, Henry AM, van der Kwast TH, Lam TB, Lardas M, Liew M, Mason MD, Moris L, Oprea-Lager DE, van der Poel HG, Rouvière O, Schoots IG, Tilki D, Wiegel T, Willemse PM, Cornford P
Eur Urol 2021 Feb;79(2):243-262. Epub 2020 Nov 7 doi: 10.1016/j.eururo.2020.09.042. PMID: 33172724

Prostate cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Parker C, Castro E, Fizazi K, Heidenreich A, Ost P, Procopio G, Tombal B, Gillessen S; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2020 Sep;31(9):1119-1134. Epub 2020 Jun 25 doi: 10.1016/j.annonc.2020.06.011. PMID: 32593798

Genital Ulcers: Differential Diagnosis and Management.

Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252

See all (18119)

Recent clinical studies

Etiology

Genital Ulcers: Differential Diagnosis and Management.

Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252

Micropenis: etiology, diagnosis and treatment approaches.

Hatipoğlu N, Kurtoğlu S
J Clin Res Pediatr Endocrinol 2013;5(4):217-23. doi: 10.4274/Jcrpe.1135. PMID: 24379029 Free PMC Article

Micropenis.

Wiygul J, Palmer LS
ScientificWorldJournal 2011 Jul 28;11:1462-9. doi: 10.1100/tsw.2011.135. PMID: 21805015 Free PMC Article

Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males.

Giuliano AR, Palefsky JM, Goldstone S, Moreira ED Jr, Penny ME, Aranda C, Vardas E, Moi H, Jessen H, Hillman R, Chang YH, Ferris D, Rouleau D, Bryan J, Marshall JB, Vuocolo S, Barr E, Radley D, Haupt RM, Guris D
N Engl J Med 2011 Feb 3;364(5):401-11. doi: 10.1056/NEJMoa0909537. PMID: 21288094 Free PMC Article

HPV infection in men.

Palefsky JM
Dis Markers 2007;23(4):261-72. doi: 10.1155/2007/159137. PMID: 17627061 Free PMC Article

See all (94735)

Diagnosis

Genital Ulcers: Differential Diagnosis and Management.

Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252

Urogenital infections.

Wagenlehner F
World J Urol 2020 Jan;38(1):1-2. doi: 10.1007/s00345-019-03039-4. PMID: 31788716

Genitourinary Procedures.

Jones MP, Mekuria K
Emerg Med Clin North Am 2019 Nov;37(4):811-819. doi: 10.1016/j.emc.2019.07.014. PMID: 31563209

Micropenis: etiology, diagnosis and treatment approaches.

Hatipoğlu N, Kurtoğlu S
J Clin Res Pediatr Endocrinol 2013;5(4):217-23. doi: 10.4274/Jcrpe.1135. PMID: 24379029 Free PMC Article

Scrotal emergencies.

Davis JE, Silverman M
Emerg Med Clin North Am 2011 Aug;29(3):469-84. doi: 10.1016/j.emc.2011.04.011. PMID: 21782069

See all (81401)

Therapy

Complications associated with intimate body piercings.

Lee B, Vangipuram R, Petersen E, Tyring SK
Dermatol Online J 2018 Jul 15;24(7) PMID: 30261561

Genital Allergic Contact Dermatitis.

Yale K, Awosika O, Rengifo-Pardo M, Ehrlich A
Dermatitis 2018 May/Jun;29(3):112-119. doi: 10.1097/DER.0000000000000371. PMID: 29698355

Micropenis.

Wiygul J, Palmer LS
ScientificWorldJournal 2011 Jul 28;11:1462-9. doi: 10.1100/tsw.2011.135. PMID: 21805015 Free PMC Article

Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males.

The International Index of Erectile Function (IIEF): a state-of-the-science review.

Rosen RC, Cappelleri JC, Gendrano N 3rd
Int J Impot Res 2002 Aug;14(4):226-44. doi: 10.1038/sj.ijir.3900857. PMID: 12152111

See all (72984)

Prognosis

Reconsidering Prostate Cancer Mortality - The Future of PSA Screening.

Welch HG, Albertsen PC
N Engl J Med 2020 Apr 16;382(16):1557-1563. doi: 10.1056/NEJMms1914228. PMID: 32294352

Epidemiology of prostate cancer in Asian countries.

Kimura T, Egawa S
Int J Urol 2018 Jun;25(6):524-531. Epub 2018 May 8 doi: 10.1111/iju.13593. PMID: 29740894

Ageing and inflammation in the male reproductive tract.

Frungieri MB, Calandra RS, Bartke A, Matzkin ME
Andrologia 2018 Dec;50(11):e13034. Epub 2018 May 8 doi: 10.1111/and.13034. PMID: 29740839

Presentation and Diagnosis of Fournier Gangrene.

Voelzke BB, Hagedorn JC
Urology 2018 Apr;114:8-13. Epub 2017 Nov 13 doi: 10.1016/j.urology.2017.10.031. PMID: 29146218

Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males.

See all (57704)

Clinical prediction guides

Genital Ulcers: Differential Diagnosis and Management.

Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252

Psoriasis and male sexuality.

Dauendorffer JN, Ly S, Beylot-Barry M
Ann Dermatol Venereol 2019 Apr;146(4):273-278. Epub 2019 Mar 28 doi: 10.1016/j.annder.2019.01.021. PMID: 30928124

Ageing and inflammation in the male reproductive tract.

Frungieri MB, Calandra RS, Bartke A, Matzkin ME
Andrologia 2018 Dec;50(11):e13034. Epub 2018 May 8 doi: 10.1111/and.13034. PMID: 29740839

Ultrasound of the male genital tract in relation to male reproductive health.

Lotti F, Maggi M
Hum Reprod Update 2015 Jan-Feb;21(1):56-83. Epub 2014 Jul 19 doi: 10.1093/humupd/dmu042. PMID: 25038770

Criteria for diagnosis of Behçet's disease. International Study Group for Behçet's Disease.

Lancet 1990 May 5;335(8697):1078-80. PMID: 1970380

See all (68527)

Recent systematic reviews

2022 Update on Prostate Cancer Epidemiology and Risk Factors-A Systematic Review.

Bergengren O, Pekala KR, Matsoukas K, Fainberg J, Mungovan SF, Bratt O, Bray F, Brawley O, Luckenbaugh AN, Mucci L, Morgan TM, Carlsson SV
Eur Urol 2023 Aug;84(2):191-206. Epub 2023 May 16 doi: 10.1016/j.eururo.2023.04.021. PMID: 37202314

European Association of Urology Guidelines on Sexual and Reproductive Health-2021 Update: Male Sexual Dysfunction.

Salonia A, Bettocchi C, Boeri L, Capogrosso P, Carvalho J, Cilesiz NC, Cocci A, Corona G, Dimitropoulos K, Gül M, Hatzichristodoulou G, Jones TH, Kadioglu A, Martínez Salamanca JI, Milenkovic U, Modgil V, Russo GI, Serefoglu EC, Tharakan T, Verze P, Minhas S; EAU Working Group on Male Sexual and Reproductive Health
Eur Urol 2021 Sep;80(3):333-357. Epub 2021 Jun 26 doi: 10.1016/j.eururo.2021.06.007. PMID: 34183196

Radiotherapy of oligometastatic prostate cancer: a systematic review.

Rogowski P, Roach M 3rd, Schmidt-Hegemann NS, Trapp C, von Bestenbostel R, Shi R, Buchner A, Stief C, Belka C, Li M
Radiat Oncol 2021 Mar 9;16(1):50. doi: 10.1186/s13014-021-01776-8. PMID: 33750437 Free PMC Article

EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.

Benign prostate hyperplasia and nutrition.

Das K, Buchholz N
Clin Nutr ESPEN 2019 Oct;33:5-11. Epub 2019 Aug 12 doi: 10.1016/j.clnesp.2019.07.015. PMID: 31451276

See all (3380)

MedGen

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Send to:

Disorder of male genital organ

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

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