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Disorder of male genital organ

MedGen UID:
42195
•Concept ID:
C0017412
•
Disease or Syndrome
Synonyms: Disease, Male Genital; Diseases, Male Genital; Genital Disease, Male; Genital Diseases, Male; Male Genital Disease; Male Genital Diseases
SNOMED CT: Male genital organ disease (64557000); Disorder of male genital organ (64557000)

Definition

Pathological processes involving the male reproductive tract (GENITALIA, MALE). [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDisorder of male genital organ

Professional guidelines

PubMed

EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer-2024 Update. Part I: Screening, Diagnosis, and Local Treatment with Curative Intent.
Cornford P, van den Bergh RCN, Briers E, Van den Broeck T, Brunckhorst O, Darraugh J, Eberli D, De Meerleer G, De Santis M, Farolfi A, Gandaglia G, Gillessen S, Grivas N, Henry AM, Lardas M, van Leenders GJLH, Liew M, Linares Espinos E, Oldenburg J, van Oort IM, Oprea-Lager DE, Ploussard G, Roberts MJ, Rouvière O, Schoots IG, Schouten N, Smith EJ, Stranne J, Wiegel T, Willemse PM, Tilki D
Eur Urol 2024 Aug;86(2):148-163. Epub 2024 Apr 13 doi: 10.1016/j.eururo.2024.03.027. PMID: 38614820
EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.
Mottet N, van den Bergh RCN, Briers E, Van den Broeck T, Cumberbatch MG, De Santis M, Fanti S, Fossati N, Gandaglia G, Gillessen S, Grivas N, Grummet J, Henry AM, van der Kwast TH, Lam TB, Lardas M, Liew M, Mason MD, Moris L, Oprea-Lager DE, van der Poel HG, Rouvière O, Schoots IG, Tilki D, Wiegel T, Willemse PM, Cornford P
Eur Urol 2021 Feb;79(2):243-262. Epub 2020 Nov 7 doi: 10.1016/j.eururo.2020.09.042. PMID: 33172724
Genital Ulcers: Differential Diagnosis and Management.
Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252

Recent clinical studies

Etiology

Genital Ulcers: Differential Diagnosis and Management.
Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252
Micropenis: etiology, diagnosis and treatment approaches.
Hatipoğlu N, Kurtoğlu S
J Clin Res Pediatr Endocrinol 2013;5(4):217-23. doi: 10.4274/Jcrpe.1135. PMID: 24379029Free PMC Article
Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males.
Giuliano AR, Palefsky JM, Goldstone S, Moreira ED Jr, Penny ME, Aranda C, Vardas E, Moi H, Jessen H, Hillman R, Chang YH, Ferris D, Rouleau D, Bryan J, Marshall JB, Vuocolo S, Barr E, Radley D, Haupt RM, Guris D
N Engl J Med 2011 Feb 3;364(5):401-11. doi: 10.1056/NEJMoa0909537. PMID: 21288094Free PMC Article
Fournier's gangrene.
Kobayashi S
Am J Surg 2008 Feb;195(2):257-8. doi: 10.1016/j.amjsurg.2007.01.042. PMID: 18083136
HPV infection in men.
Palefsky JM
Dis Markers 2007;23(4):261-72. doi: 10.1155/2007/159137. PMID: 17627061Free PMC Article

Diagnosis

Massive Scrotal Swelling.
Thomas T, Roberts-Woodbury J
Am Fam Physician 2022 Jan 1;105(1):77-78. PMID: 35029938
Genital Ulcers: Differential Diagnosis and Management.
Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252
Genitourinary Procedures.
Jones MP, Mekuria K
Emerg Med Clin North Am 2019 Nov;37(4):811-819. doi: 10.1016/j.emc.2019.07.014. PMID: 31563209
Micropenis: etiology, diagnosis and treatment approaches.
Hatipoğlu N, Kurtoğlu S
J Clin Res Pediatr Endocrinol 2013;5(4):217-23. doi: 10.4274/Jcrpe.1135. PMID: 24379029Free PMC Article
Inconspicuous penis.
Srinivasan AK, Palmer LS, Palmer JS
ScientificWorldJournal 2011;11:2559-64. Epub 2011 Dec 29 doi: 10.1100/2011/238519. PMID: 22235186Free PMC Article

Therapy

Inconspicuous penis.
Srinivasan AK, Palmer LS, Palmer JS
ScientificWorldJournal 2011;11:2559-64. Epub 2011 Dec 29 doi: 10.1100/2011/238519. PMID: 22235186Free PMC Article
Micropenis.
Wiygul J, Palmer LS
ScientificWorldJournal 2011 Jul 28;11:1462-9. doi: 10.1100/tsw.2011.135. PMID: 21805015Free PMC Article
Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males.
Giuliano AR, Palefsky JM, Goldstone S, Moreira ED Jr, Penny ME, Aranda C, Vardas E, Moi H, Jessen H, Hillman R, Chang YH, Ferris D, Rouleau D, Bryan J, Marshall JB, Vuocolo S, Barr E, Radley D, Haupt RM, Guris D
N Engl J Med 2011 Feb 3;364(5):401-11. doi: 10.1056/NEJMoa0909537. PMID: 21288094Free PMC Article
A management algorithm for hematospermia.
Aslam MI, Cheetham P, Miller MA
Nat Rev Urol 2009 Jul;6(7):398-402. doi: 10.1038/nrurol.2009.98. PMID: 19578357
Fournier's gangrene.
Kobayashi S
Am J Surg 2008 Feb;195(2):257-8. doi: 10.1016/j.amjsurg.2007.01.042. PMID: 18083136

Prognosis

The Management of Incidental Prostate Cancer Following TURP.
Matanhelia DM, Croghan S, Nason GJ, O’Connell C, Galvin DJ
Ir Med J 2019 Feb 14;112(2):866. PMID: 30875166
Benefits and risks of prostate cancer screening.
Fornara P, Theil G, Schaefer C, Heß J, Rübben H
Oncol Res Treat 2014;37 Suppl 3:29-37. Epub 2014 Aug 29 doi: 10.1159/000363756. PMID: 25195830
Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males.
Giuliano AR, Palefsky JM, Goldstone S, Moreira ED Jr, Penny ME, Aranda C, Vardas E, Moi H, Jessen H, Hillman R, Chang YH, Ferris D, Rouleau D, Bryan J, Marshall JB, Vuocolo S, Barr E, Radley D, Haupt RM, Guris D
N Engl J Med 2011 Feb 3;364(5):401-11. doi: 10.1056/NEJMoa0909537. PMID: 21288094Free PMC Article
Fournier's gangrene.
Kobayashi S
Am J Surg 2008 Feb;195(2):257-8. doi: 10.1016/j.amjsurg.2007.01.042. PMID: 18083136
Fournier's gangrene.
Morpurgo E, Galandiuk S
Surg Clin North Am 2002 Dec;82(6):1213-24. doi: 10.1016/s0039-6109(02)00058-0. PMID: 12516849

Clinical prediction guides

Borderline Gleason scores: communication is the key.
Varma M, Delahunt B, van der Kwast TH, Williamson SR, Berney DM
J Clin Pathol 2020 Oct;73(10):616-617. Epub 2020 Aug 7 doi: 10.1136/jclinpath-2020-206948. PMID: 32769213
Genital Ulcers: Differential Diagnosis and Management.
Roett MA
Am Fam Physician 2020 Mar 15;101(6):355-361. PMID: 32163252
PIRADS 2.0: what is new?
Turkbey B, Choyke PL
Diagn Interv Radiol 2015 Sep-Oct;21(5):382-4. doi: 10.5152/dir.2015.15099. PMID: 26200484Free PMC Article
Leiomyosarcoma of the spermatic cord.
Watanabe J, Soma T, Kawa G, Hida S, Koisi M
Int J Urol 1999 Oct;6(10):536-8. doi: 10.1046/j.1442-2042.1999.00100.x. PMID: 10533906
Criteria for diagnosis of Behçet's disease. International Study Group for Behçet's Disease.
Lancet 1990 May 5;335(8697):1078-80. PMID: 1970380

Recent systematic reviews

EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer-2024 Update. Part I: Screening, Diagnosis, and Local Treatment with Curative Intent.
Cornford P, van den Bergh RCN, Briers E, Van den Broeck T, Brunckhorst O, Darraugh J, Eberli D, De Meerleer G, De Santis M, Farolfi A, Gandaglia G, Gillessen S, Grivas N, Henry AM, Lardas M, van Leenders GJLH, Liew M, Linares Espinos E, Oldenburg J, van Oort IM, Oprea-Lager DE, Ploussard G, Roberts MJ, Rouvière O, Schoots IG, Schouten N, Smith EJ, Stranne J, Wiegel T, Willemse PM, Tilki D
Eur Urol 2024 Aug;86(2):148-163. Epub 2024 Apr 13 doi: 10.1016/j.eururo.2024.03.027. PMID: 38614820
2022 Update on Prostate Cancer Epidemiology and Risk Factors-A Systematic Review.
Bergengren O, Pekala KR, Matsoukas K, Fainberg J, Mungovan SF, Bratt O, Bray F, Brawley O, Luckenbaugh AN, Mucci L, Morgan TM, Carlsson SV
Eur Urol 2023 Aug;84(2):191-206. Epub 2023 May 16 doi: 10.1016/j.eururo.2023.04.021. PMID: 37202314Free PMC Article
European Association of Urology Guidelines on Sexual and Reproductive Health-2021 Update: Male Sexual Dysfunction.
Salonia A, Bettocchi C, Boeri L, Capogrosso P, Carvalho J, Cilesiz NC, Cocci A, Corona G, Dimitropoulos K, Gül M, Hatzichristodoulou G, Jones TH, Kadioglu A, Martínez Salamanca JI, Milenkovic U, Modgil V, Russo GI, Serefoglu EC, Tharakan T, Verze P, Minhas S; EAU Working Group on Male Sexual and Reproductive Health
Eur Urol 2021 Sep;80(3):333-357. Epub 2021 Jun 26 doi: 10.1016/j.eururo.2021.06.007. PMID: 34183196
Radiotherapy of oligometastatic prostate cancer: a systematic review.
Rogowski P, Roach M 3rd, Schmidt-Hegemann NS, Trapp C, von Bestenbostel R, Shi R, Buchner A, Stief C, Belka C, Li M
Radiat Oncol 2021 Mar 9;16(1):50. doi: 10.1186/s13014-021-01776-8. PMID: 33750437Free PMC Article
EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.
Mottet N, van den Bergh RCN, Briers E, Van den Broeck T, Cumberbatch MG, De Santis M, Fanti S, Fossati N, Gandaglia G, Gillessen S, Grivas N, Grummet J, Henry AM, van der Kwast TH, Lam TB, Lardas M, Liew M, Mason MD, Moris L, Oprea-Lager DE, van der Poel HG, Rouvière O, Schoots IG, Tilki D, Wiegel T, Willemse PM, Cornford P
Eur Urol 2021 Feb;79(2):243-262. Epub 2020 Nov 7 doi: 10.1016/j.eururo.2020.09.042. PMID: 33172724

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