U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TFG-ALKshort Fusion Protein Expression

MedGen UID:
271738
Concept ID:
C1515160
Cell or Molecular Dysfunction

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTFG-ALKshort Fusion Protein Expression

Professional guidelines

PubMed

Yang L, Wu C, Parker E, Li Y, Dong Y, Tucker L, Brann DW, Lin HW, Zhang Q
Theranostics 2022;12(5):2205-2231. Epub 2022 Feb 14 doi: 10.7150/thno.70756. PMID: 35265207Free PMC Article
Gulley JL, Schlom J, Barcellos-Hoff MH, Wang XJ, Seoane J, Audhuy F, Lan Y, Dussault I, Moustakas A
Mol Oncol 2022 Jun;16(11):2117-2134. Epub 2022 Jan 4 doi: 10.1002/1878-0261.13146. PMID: 34854206Free PMC Article
Gao Q, Liang WW, Foltz SM, Mutharasu G, Jayasinghe RG, Cao S, Liao WW, Reynolds SM, Wyczalkowski MA, Yao L, Yu L, Sun SQ; Fusion Analysis Working Group; Cancer Genome Atlas Research Network, Chen K, Lazar AJ, Fields RC, Wendl MC, Van Tine BA, Vij R, Chen F, Nykter M, Shmulevich I, Ding L
Cell Rep 2018 Apr 3;23(1):227-238.e3. doi: 10.1016/j.celrep.2018.03.050. PMID: 29617662Free PMC Article

Recent clinical studies

Etiology

Dall'Aglio L, Lewis CM, Pain O
Biol Psychiatry 2021 Mar 15;89(6):627-636. Epub 2020 Sep 12 doi: 10.1016/j.biopsych.2020.09.010. PMID: 33279206Free PMC Article
Arindrarto W, Borràs DM, de Groen RAL, van den Berg RR, Locher IJ, van Diessen SAME, van der Holst R, van der Meijden ED, Honders MW, de Leeuw RH, Verlaat W, Jedema I, Kroes WGM, Knijnenburg J, van Wezel T, Vermaat JSP, Valk PJM, Janssen B, de Knijff P, van Bergen CAM, van den Akker EB, Hoen PAC', Kiełbasa SM, Laros JFJ, Griffioen M, Veelken H
Leukemia 2021 Jan;35(1):47-61. Epub 2020 Mar 3 doi: 10.1038/s41375-020-0762-8. PMID: 32127641Free PMC Article
Gomes-Silva D, Srinivasan M, Sharma S, Lee CM, Wagner DL, Davis TH, Rouce RH, Bao G, Brenner MK, Mamonkin M
Blood 2017 Jul 20;130(3):285-296. Epub 2017 May 24 doi: 10.1182/blood-2017-01-761320. PMID: 28539325Free PMC Article
Gu Z, Churchman M, Roberts K, Li Y, Liu Y, Harvey RC, McCastlain K, Reshmi SC, Payne-Turner D, Iacobucci I, Shao Y, Chen IM, Valentine M, Pei D, Mungall KL, Mungall AJ, Ma Y, Moore R, Marra M, Stonerock E, Gastier-Foster JM, Devidas M, Dai Y, Wood B, Borowitz M, Larsen EE, Maloney K, Mattano LA Jr, Angiolillo A, Salzer WL, Burke MJ, Gianni F, Spinelli O, Radich JP, Minden MD, Moorman AV, Patel B, Fielding AK, Rowe JM, Luger SM, Bhatia R, Aldoss I, Forman SJ, Kohlschmidt J, Mrózek K, Marcucci G, Bloomfield CD, Stock W, Kornblau S, Kantarjian HM, Konopleva M, Paietta E, Willman CL, Loh ML, Hunger SP, Mullighan CG
Nat Commun 2016 Nov 8;7:13331. doi: 10.1038/ncomms13331. PMID: 27824051Free PMC Article
Lilljebjörn H, Henningsson R, Hyrenius-Wittsten A, Olsson L, Orsmark-Pietras C, von Palffy S, Askmyr M, Rissler M, Schrappe M, Cario G, Castor A, Pronk CJ, Behrendtz M, Mitelman F, Johansson B, Paulsson K, Andersson AK, Fontes M, Fioretos T
Nat Commun 2016 Jun 6;7:11790. doi: 10.1038/ncomms11790. PMID: 27265895Free PMC Article

Diagnosis

Arindrarto W, Borràs DM, de Groen RAL, van den Berg RR, Locher IJ, van Diessen SAME, van der Holst R, van der Meijden ED, Honders MW, de Leeuw RH, Verlaat W, Jedema I, Kroes WGM, Knijnenburg J, van Wezel T, Vermaat JSP, Valk PJM, Janssen B, de Knijff P, van Bergen CAM, van den Akker EB, Hoen PAC', Kiełbasa SM, Laros JFJ, Griffioen M, Veelken H
Leukemia 2021 Jan;35(1):47-61. Epub 2020 Mar 3 doi: 10.1038/s41375-020-0762-8. PMID: 32127641Free PMC Article
Gu Z, Churchman M, Roberts K, Li Y, Liu Y, Harvey RC, McCastlain K, Reshmi SC, Payne-Turner D, Iacobucci I, Shao Y, Chen IM, Valentine M, Pei D, Mungall KL, Mungall AJ, Ma Y, Moore R, Marra M, Stonerock E, Gastier-Foster JM, Devidas M, Dai Y, Wood B, Borowitz M, Larsen EE, Maloney K, Mattano LA Jr, Angiolillo A, Salzer WL, Burke MJ, Gianni F, Spinelli O, Radich JP, Minden MD, Moorman AV, Patel B, Fielding AK, Rowe JM, Luger SM, Bhatia R, Aldoss I, Forman SJ, Kohlschmidt J, Mrózek K, Marcucci G, Bloomfield CD, Stock W, Kornblau S, Kantarjian HM, Konopleva M, Paietta E, Willman CL, Loh ML, Hunger SP, Mullighan CG
Nat Commun 2016 Nov 8;7:13331. doi: 10.1038/ncomms13331. PMID: 27824051Free PMC Article
Liu YF, Wang BY, Zhang WN, Huang JY, Li BS, Zhang M, Jiang L, Li JF, Wang MJ, Dai YJ, Zhang ZG, Wang Q, Kong J, Chen B, Zhu YM, Weng XQ, Shen ZX, Li JM, Wang J, Yan XJ, Li Y, Liang YM, Liu L, Chen XQ, Zhang WG, Yan JS, Hu JD, Shen SH, Chen J, Gu LJ, Pei D, Li Y, Wu G, Zhou X, Ren RB, Cheng C, Yang JJ, Wang KK, Wang SY, Zhang J, Mi JQ, Pui CH, Tang JY, Chen Z, Chen SJ
EBioMedicine 2016 Jun;8:173-183. Epub 2016 May 13 doi: 10.1016/j.ebiom.2016.04.038. PMID: 27428428Free PMC Article
Seo JS, Ju YS, Lee WC, Shin JY, Lee JK, Bleazard T, Lee J, Jung YJ, Kim JO, Shin JY, Yu SB, Kim J, Lee ER, Kang CH, Park IK, Rhee H, Lee SH, Kim JI, Kang JH, Kim YT
Genome Res 2012 Nov;22(11):2109-19. Epub 2012 Sep 13 doi: 10.1101/gr.145144.112. PMID: 22975805Free PMC Article
Gossen M, Bujard H
Proc Natl Acad Sci U S A 1992 Jun 15;89(12):5547-51. doi: 10.1073/pnas.89.12.5547. PMID: 1319065Free PMC Article

Therapy

Liu X, Miao Y, Liu C, Lu W, Feng Q, Zhang Q
Front Immunol 2023;14:1161311. Epub 2023 May 1 doi: 10.3389/fimmu.2023.1161311. PMID: 37197658Free PMC Article
Guo R, Luo J, Chang J, Rekhtman N, Arcila M, Drilon A
Nat Rev Clin Oncol 2020 Sep;17(9):569-587. Epub 2020 Jun 8 doi: 10.1038/s41571-020-0377-z. PMID: 32514147Free PMC Article
Li AY, McCusker MG, Russo A, Scilla KA, Gittens A, Arensmeyer K, Mehra R, Adamo V, Rolfo C
Cancer Treat Rev 2019 Dec;81:101911. Epub 2019 Oct 30 doi: 10.1016/j.ctrv.2019.101911. PMID: 31715421
Ye Z, Li Z, Jin H, Qian Q
Adv Exp Med Biol 2016;909:139-67. doi: 10.1007/978-94-017-7555-7_3. PMID: 27240458
Seo JS, Ju YS, Lee WC, Shin JY, Lee JK, Bleazard T, Lee J, Jung YJ, Kim JO, Shin JY, Yu SB, Kim J, Lee ER, Kang CH, Park IK, Rhee H, Lee SH, Kim JI, Kang JH, Kim YT
Genome Res 2012 Nov;22(11):2109-19. Epub 2012 Sep 13 doi: 10.1101/gr.145144.112. PMID: 22975805Free PMC Article

Prognosis

Alerasool N, Leng H, Lin ZY, Gingras AC, Taipale M
Mol Cell 2022 Feb 3;82(3):677-695.e7. Epub 2022 Jan 10 doi: 10.1016/j.molcel.2021.12.008. PMID: 35016035
Arindrarto W, Borràs DM, de Groen RAL, van den Berg RR, Locher IJ, van Diessen SAME, van der Holst R, van der Meijden ED, Honders MW, de Leeuw RH, Verlaat W, Jedema I, Kroes WGM, Knijnenburg J, van Wezel T, Vermaat JSP, Valk PJM, Janssen B, de Knijff P, van Bergen CAM, van den Akker EB, Hoen PAC', Kiełbasa SM, Laros JFJ, Griffioen M, Veelken H
Leukemia 2021 Jan;35(1):47-61. Epub 2020 Mar 3 doi: 10.1038/s41375-020-0762-8. PMID: 32127641Free PMC Article
Li JF, Dai YT, Lilljebjörn H, Shen SH, Cui BW, Bai L, Liu YF, Qian MX, Kubota Y, Kiyoi H, Matsumura I, Miyazaki Y, Olsson L, Tan AM, Ariffin H, Chen J, Takita J, Yasuda T, Mano H, Johansson B, Yang JJ, Yeoh AE, Hayakawa F, Chen Z, Pui CH, Fioretos T, Chen SJ, Huang JY
Proc Natl Acad Sci U S A 2018 Dec 11;115(50):E11711-E11720. Epub 2018 Nov 28 doi: 10.1073/pnas.1814397115. PMID: 30487223Free PMC Article
Liu YF, Wang BY, Zhang WN, Huang JY, Li BS, Zhang M, Jiang L, Li JF, Wang MJ, Dai YJ, Zhang ZG, Wang Q, Kong J, Chen B, Zhu YM, Weng XQ, Shen ZX, Li JM, Wang J, Yan XJ, Li Y, Liang YM, Liu L, Chen XQ, Zhang WG, Yan JS, Hu JD, Shen SH, Chen J, Gu LJ, Pei D, Li Y, Wu G, Zhou X, Ren RB, Cheng C, Yang JJ, Wang KK, Wang SY, Zhang J, Mi JQ, Pui CH, Tang JY, Chen Z, Chen SJ
EBioMedicine 2016 Jun;8:173-183. Epub 2016 May 13 doi: 10.1016/j.ebiom.2016.04.038. PMID: 27428428Free PMC Article
Trinh R, Gurbaxani B, Morrison SL, Seyfzadeh M
Mol Immunol 2004 Jan;40(10):717-22. doi: 10.1016/j.molimm.2003.08.006. PMID: 14644097

Clinical prediction guides

Xia Y, Jin Z, Zhang C, Ouyang L, Dong Y, Li J, Guo L, Jing B, Shi Y, Miao S, Xi R
Nat Commun 2023 Sep 23;14(1):5935. doi: 10.1038/s41467-023-41649-0. PMID: 37741817Free PMC Article
Watson S, Perrin V, Guillemot D, Reynaud S, Coindre JM, Karanian M, Guinebretière JM, Freneaux P, Le Loarer F, Bouvet M, Galmiche-Rolland L, Larousserie F, Longchampt E, Ranchere-Vince D, Pierron G, Delattre O, Tirode F
J Pathol 2018 May;245(1):29-40. Epub 2018 Mar 30 doi: 10.1002/path.5053. PMID: 29431183
Ross JS, Wang K, Chmielecki J, Gay L, Johnson A, Chudnovsky J, Yelensky R, Lipson D, Ali SM, Elvin JA, Vergilio JA, Roels S, Miller VA, Nakamura BN, Gray A, Wong MK, Stephens PJ
Int J Cancer 2016 Feb 15;138(4):881-90. Epub 2015 Sep 8 doi: 10.1002/ijc.29825. PMID: 26314551Free PMC Article
Tsiliki G, Kossida S
J Proteomics 2011 Nov 18;74(12):2774-85. Epub 2011 Jul 13 doi: 10.1016/j.jprot.2011.07.001. PMID: 21767675
Trinh R, Gurbaxani B, Morrison SL, Seyfzadeh M
Mol Immunol 2004 Jan;40(10):717-22. doi: 10.1016/j.molimm.2003.08.006. PMID: 14644097

Recent systematic reviews

Bienstman T, Güvenç C, Garmyn M
Int J Mol Sci 2024 May 25;25(11) doi: 10.3390/ijms25115760. PMID: 38891945Free PMC Article
Nusir A, Sinclair P, Kabbani N
Biomolecules 2023 Nov 11;13(11) doi: 10.3390/biom13111638. PMID: 38002320Free PMC Article
Henry NL, Somerfield MR, Dayao Z, Elias A, Kalinsky K, McShane LM, Moy B, Park BH, Shanahan KM, Sharma P, Shatsky R, Stringer-Reasor E, Telli M, Turner NC, DeMichele A
J Clin Oncol 2022 Sep 20;40(27):3205-3221. Epub 2022 Jun 27 doi: 10.1200/JCO.22.01063. PMID: 35759724
Rao AKDM, Rajkumar T, Mani S
Mol Biol Rep 2017 Apr;44(2):203-218. Epub 2017 Apr 8 doi: 10.1007/s11033-017-4103-6. PMID: 28391434
Masson P, Henderson L, Chapman JR, Craig JC, Webster AC
Cochrane Database Syst Rev 2014 Nov 24;2014(11):CD010699. doi: 10.1002/14651858.CD010699.pub2. PMID: 25416857Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...