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t(11;22)(q24;q12)

MedGen UID:
271864
•Concept ID:
C1515713
•
Cell or Molecular Dysfunction
Synonyms: t(11;22) (q24;q12); t(11;22) EWS-FLI1; t(11;22)(q24;q12)(EWS/FLI-1)

Definition

A chromosomal translocation involving the FLI1 gene on chromosome 11q24 and the EWSR1 gene on chromosome 22q12. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVt(11;22)(q24;q12)

Professional guidelines

PubMed

Practical Approach in Management of Extraosseous Ewing's Sarcoma of Head and Neck: A Case Series and Review of literature.
Sethi P, Singh A, Srinivas BH, Ganesh RN, Kayal S
Gulf J Oncolog 2022 May;1(39):79-88. PMID: 35695350
Oncogene-targeted antisense oligonucleotides for the treatment of Ewing sarcoma.
Maksimenko A, Malvy C
Expert Opin Ther Targets 2005 Aug;9(4):825-30. doi: 10.1517/14728222.9.4.825. PMID: 16083345
Assessment of molecular genetic detection of chromosome translocations in the differential diagnosis of pediatric sarcomas.
Dockhorn-Dworniczak B, Schäfer KL, Blasius S, Christiansen H, Koscielniak E, Ritter J, Winkelmann W, Jürgens H, Böcker W
Klin Padiatr 1997 Jul-Aug;209(4):156-64. doi: 10.1055/s-2008-1043964. PMID: 9293447

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