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Localized Askin Tumor

MedGen UID:
272111
•Concept ID:
C1321778
•
Neoplastic Process
Synonym: Localized Askin's Tumor

Definition

A small round cell tumor confined to a specific area of the thoracic cavity without evidence of spread to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocalized Askin Tumor

Professional guidelines

PubMed

Bispecific antibodies for the treatment of neuroblastoma.
Espinosa-Cotton M, Cheung NV
Pharmacol Ther 2022 Sep;237:108241. Epub 2022 Jul 10 doi: 10.1016/j.pharmthera.2022.108241. PMID: 35830901Free PMC Article
Management of Neuroblastoma in Pediatric Patients.
Croteau N, Nuchtern J, LaQuaglia MP
Surg Oncol Clin N Am 2021 Apr;30(2):291-304. Epub 2021 Feb 10 doi: 10.1016/j.soc.2020.11.010. PMID: 33706901
Overview and recent advances in the treatment of neuroblastoma.
Whittle SB, Smith V, Doherty E, Zhao S, McCarty S, Zage PE
Expert Rev Anticancer Ther 2017 Apr;17(4):369-386. Epub 2017 Mar 15 doi: 10.1080/14737140.2017.1285230. PMID: 28142287

Recent clinical studies

Etiology

Advancing therapy for neuroblastoma.
Qiu B, Matthay KK
Nat Rev Clin Oncol 2022 Aug;19(8):515-533. Epub 2022 May 25 doi: 10.1038/s41571-022-00643-z. PMID: 35614230
Immunotherapy of Neuroblastoma: Facts and Hopes.
Anderson J, Majzner RG, Sondel PM
Clin Cancer Res 2022 Aug 2;28(15):3196-3206. doi: 10.1158/1078-0432.CCR-21-1356. PMID: 35435953Free PMC Article
Management of Neuroblastoma in Pediatric Patients.
Croteau N, Nuchtern J, LaQuaglia MP
Surg Oncol Clin N Am 2021 Apr;30(2):291-304. Epub 2021 Feb 10 doi: 10.1016/j.soc.2020.11.010. PMID: 33706901
Overview and recent advances in the treatment of neuroblastoma.
Whittle SB, Smith V, Doherty E, Zhao S, McCarty S, Zage PE
Expert Rev Anticancer Ther 2017 Apr;17(4):369-386. Epub 2017 Mar 15 doi: 10.1080/14737140.2017.1285230. PMID: 28142287
Recent advances in neuroblastoma.
Maris JM
N Engl J Med 2010 Jun 10;362(23):2202-11. doi: 10.1056/NEJMra0804577. PMID: 20558371Free PMC Article

Diagnosis

Cellular senescence in neuroblastoma.
Zanotti S, Decaesteker B, Vanhauwaert S, De Wilde B, De Vos WH, Speleman F
Br J Cancer 2022 Jun;126(11):1529-1538. Epub 2022 Feb 23 doi: 10.1038/s41416-022-01755-0. PMID: 35197583Free PMC Article
Overview and recent advances in the treatment of neuroblastoma.
Whittle SB, Smith V, Doherty E, Zhao S, McCarty S, Zage PE
Expert Rev Anticancer Ther 2017 Apr;17(4):369-386. Epub 2017 Mar 15 doi: 10.1080/14737140.2017.1285230. PMID: 28142287
Neuroblastoma.
Humpl T
World J Urol 1995;13(4):233-9. doi: 10.1007/BF00182969. PMID: 8528298
Esthesioneuroblastoma.
Shah JP, Feghali J
CA Cancer J Clin 1983 May-Jun;33(3):154-9. doi: 10.3322/canjclin.33.3.154. PMID: 6404523
Esthesioneuroblastoma.
Shah JP, Feghali J
Am J Surg 1981 Oct;142(4):456-8. doi: 10.1016/0002-9610(81)90374-3. PMID: 7283046

Therapy

Advancing therapy for neuroblastoma.
Qiu B, Matthay KK
Nat Rev Clin Oncol 2022 Aug;19(8):515-533. Epub 2022 May 25 doi: 10.1038/s41571-022-00643-z. PMID: 35614230
Immunotherapy of Neuroblastoma: Facts and Hopes.
Anderson J, Majzner RG, Sondel PM
Clin Cancer Res 2022 Aug 2;28(15):3196-3206. doi: 10.1158/1078-0432.CCR-21-1356. PMID: 35435953Free PMC Article
Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis.
Heczey A, Courtney AN, Montalbano A, Robinson S, Liu K, Li M, Ghatwai N, Dakhova O, Liu B, Raveh-Sadka T, Chauvin-Fleurence CN, Xu X, Ngai H, Di Pierro EJ, Savoldo B, Dotti G, Metelitsa LS
Nat Med 2020 Nov;26(11):1686-1690. Epub 2020 Oct 12 doi: 10.1038/s41591-020-1074-2. PMID: 33046868
Anti-GD2 immunotherapy for neuroblastoma.
Sait S, Modak S
Expert Rev Anticancer Ther 2017 Oct;17(10):889-904. Epub 2017 Aug 14 doi: 10.1080/14737140.2017.1364995. PMID: 28780888Free PMC Article
Recent advances in neuroblastoma.
Maris JM
N Engl J Med 2010 Jun 10;362(23):2202-11. doi: 10.1056/NEJMra0804577. PMID: 20558371Free PMC Article

Prognosis

Anti-GD2 immunotherapy for neuroblastoma.
Sait S, Modak S
Expert Rev Anticancer Ther 2017 Oct;17(10):889-904. Epub 2017 Aug 14 doi: 10.1080/14737140.2017.1364995. PMID: 28780888Free PMC Article
Overview and recent advances in the treatment of neuroblastoma.
Whittle SB, Smith V, Doherty E, Zhao S, McCarty S, Zage PE
Expert Rev Anticancer Ther 2017 Apr;17(4):369-386. Epub 2017 Mar 15 doi: 10.1080/14737140.2017.1285230. PMID: 28142287
Neuroblastoma.
Matthay KK, Maris JM, Schleiermacher G, Nakagawara A, Mackall CL, Diller L, Weiss WA
Nat Rev Dis Primers 2016 Nov 10;2:16078. doi: 10.1038/nrdp.2016.78. PMID: 27830764
Recent advances in neuroblastoma.
Maris JM
N Engl J Med 2010 Jun 10;362(23):2202-11. doi: 10.1056/NEJMra0804577. PMID: 20558371Free PMC Article
Neuroblastoma.
Humpl T
World J Urol 1995;13(4):233-9. doi: 10.1007/BF00182969. PMID: 8528298

Clinical prediction guides

Anti-GD2 Antibody Dinutuximab Beta and Low-Dose Interleukin 2 After Haploidentical Stem-Cell Transplantation in Patients With Relapsed Neuroblastoma: A Multicenter, Phase I/II Trial.
Flaadt T, Ladenstein RL, Ebinger M, Lode HN, Arnardóttir HB, Poetschger U, Schwinger W, Meisel R, Schuster FR, Döring M, Ambros PF, Queudeville M, Fuchs J, Warmann SW, Schäfer J, Seitz C, Schlegel P, Brecht IB, Holzer U, Feuchtinger T, Simon T, Schulte JH, Eggert A, Teltschik HM, Illhardt T, Handgretinger R, Lang P
J Clin Oncol 2023 Jun 10;41(17):3135-3148. Epub 2023 Feb 28 doi: 10.1200/JCO.22.01630. PMID: 36854071Free PMC Article
Cellular senescence in neuroblastoma.
Zanotti S, Decaesteker B, Vanhauwaert S, De Wilde B, De Vos WH, Speleman F
Br J Cancer 2022 Jun;126(11):1529-1538. Epub 2022 Feb 23 doi: 10.1038/s41416-022-01755-0. PMID: 35197583Free PMC Article
Anlotinib Induces a T Cell-Inflamed Tumor Microenvironment by Facilitating Vessel Normalization and Enhances the Efficacy of PD-1 Checkpoint Blockade in Neuroblastoma.
Su Y, Luo B, Lu Y, Wang D, Yan J, Zheng J, Xiao J, Wang Y, Xue Z, Yin J, Chen P, Li L, Zhao Q
Clin Cancer Res 2022 Feb 15;28(4):793-809. doi: 10.1158/1078-0432.CCR-21-2241. PMID: 34844980Free PMC Article
Management of Neuroblastoma in Pediatric Patients.
Croteau N, Nuchtern J, LaQuaglia MP
Surg Oncol Clin N Am 2021 Apr;30(2):291-304. Epub 2021 Feb 10 doi: 10.1016/j.soc.2020.11.010. PMID: 33706901
Neuroblastoma.
Davidoff AM
Semin Pediatr Surg 2012 Feb;21(1):2-14. doi: 10.1053/j.sempedsurg.2011.10.009. PMID: 22248965Free PMC Article

Recent systematic reviews

Ophthalmologic Manifestations of Neuroblastoma: A Systemic Review.
Kuchalska K, Derwich K, Gotz-Więckowska A
J Pediatr Hematol Oncol 2023 Mar 1;45(2):47-56. Epub 2022 Sep 13 doi: 10.1097/MPH.0000000000002543. PMID: 36161977
Long-term carcinologic results of advanced esthesioneuroblastoma: a systematic review.
De Bonnecaze G, Lepage B, Rimmer J, Al Hawat A, Vairel B, Serrano E, Chaput B, Vergez S
Eur Arch Otorhinolaryngol 2016 Jan;273(1):21-6. Epub 2014 Oct 17 doi: 10.1007/s00405-014-3320-z. PMID: 25323151
Endoscopic endonasal compared with anterior craniofacial and combined cranionasal resection of esthesioneuroblastomas.
Komotar RJ, Starke RM, Raper DM, Anand VK, Schwartz TH
World Neurosurg 2013 Jul-Aug;80(1-2):148-59. Epub 2012 Dec 7 doi: 10.1016/j.wneu.2012.12.003. PMID: 23228365
Minimally invasive adrenalectomy in children.
Heloury Y, Muthucumaru M, Panabokke G, Cheng W, Kimber C, Leclair MD
J Pediatr Surg 2012 Feb;47(2):415-21. doi: 10.1016/j.jpedsurg.2011.08.003. PMID: 22325405
High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma.
Yalçin B, Kremer LC, Caron HN, van Dalen EC
Cochrane Database Syst Rev 2010 May 12;(5):CD006301. doi: 10.1002/14651858.CD006301.pub2. PMID: 20464740

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