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Localized Askin Tumor

MedGen UID:
272111
Concept ID:
C1321778
Neoplastic Process
Synonym: Localized Askin's Tumor

Definition

A small round cell tumor confined to a specific area of the thoracic cavity without evidence of spread to other anatomic sites. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Slotkin EK, Meyers PA
Pediatr Blood Cancer 2023 Jan;70(1):e30005. Epub 2022 Oct 2 doi: 10.1002/pbc.30005. PMID: 36184748Free PMC Article
Croteau N, Nuchtern J, LaQuaglia MP
Surg Oncol Clin N Am 2021 Apr;30(2):291-304. Epub 2021 Feb 10 doi: 10.1016/j.soc.2020.11.010. PMID: 33706901
Whittle SB, Smith V, Doherty E, Zhao S, McCarty S, Zage PE
Expert Rev Anticancer Ther 2017 Apr;17(4):369-386. Epub 2017 Mar 15 doi: 10.1080/14737140.2017.1285230. PMID: 28142287

Recent clinical studies

Etiology

Gao J, Fosbrook C, Gibson J, Underwood TJ, Gray JC, Walters ZS
Cancer Treat Rev 2023 Sep;119:102600. Epub 2023 Jul 13 doi: 10.1016/j.ctrv.2023.102600. PMID: 37467626
Whittle SB, Smith V, Doherty E, Zhao S, McCarty S, Zage PE
Expert Rev Anticancer Ther 2017 Apr;17(4):369-386. Epub 2017 Mar 15 doi: 10.1080/14737140.2017.1285230. PMID: 28142287
Pugh TJ, Morozova O, Attiyeh EF, Asgharzadeh S, Wei JS, Auclair D, Carter SL, Cibulskis K, Hanna M, Kiezun A, Kim J, Lawrence MS, Lichenstein L, McKenna A, Pedamallu CS, Ramos AH, Shefler E, Sivachenko A, Sougnez C, Stewart C, Ally A, Birol I, Chiu R, Corbett RD, Hirst M, Jackman SD, Kamoh B, Khodabakshi AH, Krzywinski M, Lo A, Moore RA, Mungall KL, Qian J, Tam A, Thiessen N, Zhao Y, Cole KA, Diamond M, Diskin SJ, Mosse YP, Wood AC, Ji L, Sposto R, Badgett T, London WB, Moyer Y, Gastier-Foster JM, Smith MA, Guidry Auvil JM, Gerhard DS, Hogarty MD, Jones SJ, Lander ES, Gabriel SB, Getz G, Seeger RC, Khan J, Marra MA, Meyerson M, Maris JM
Nat Genet 2013 Mar;45(3):279-84. Epub 2013 Jan 20 doi: 10.1038/ng.2529. PMID: 23334666Free PMC Article
Davidoff AM
Semin Pediatr Surg 2012 Feb;21(1):2-14. doi: 10.1053/j.sempedsurg.2011.10.009. PMID: 22248965Free PMC Article
Maris JM
N Engl J Med 2010 Jun 10;362(23):2202-11. doi: 10.1056/NEJMra0804577. PMID: 20558371Free PMC Article

Diagnosis

Zanotti S, Decaesteker B, Vanhauwaert S, De Wilde B, De Vos WH, Speleman F
Br J Cancer 2022 Jun;126(11):1529-1538. Epub 2022 Feb 23 doi: 10.1038/s41416-022-01755-0. PMID: 35197583Free PMC Article
Fisher JPH, Tweddle DA
Semin Fetal Neonatal Med 2012 Aug;17(4):207-215. Epub 2012 Jun 4 doi: 10.1016/j.siny.2012.05.002. PMID: 22673527
Nuchtern JG
Semin Pediatr Surg 2006 Feb;15(1):10-6. doi: 10.1053/j.sempedsurg.2005.11.003. PMID: 16458841
Shah JP, Feghali J
Am J Surg 1981 Oct;142(4):456-8. doi: 10.1016/0002-9610(81)90374-3. PMID: 7283046
Elkon D, Hightower SI, Lim ML, Cantrell RW, Constable WC
Cancer 1979 Sep;44(3):1087-94. doi: 10.1002/1097-0142(197909)44:3<1087::aid-cncr2820440343>3.0.co;2-a. PMID: 383268

Therapy

Slotkin EK, Meyers PA
Pediatr Blood Cancer 2023 Jan;70(1):e30005. Epub 2022 Oct 2 doi: 10.1002/pbc.30005. PMID: 36184748Free PMC Article
Qiu B, Matthay KK
Nat Rev Clin Oncol 2022 Aug;19(8):515-533. Epub 2022 May 25 doi: 10.1038/s41571-022-00643-z. PMID: 35614230
Anderson J, Majzner RG, Sondel PM
Clin Cancer Res 2022 Aug 2;28(15):3196-3206. doi: 10.1158/1078-0432.CCR-21-1356. PMID: 35435953Free PMC Article
Fletcher JI, Ziegler DS, Trahair TN, Marshall GM, Haber M, Norris MD
Nat Rev Cancer 2018 Jun;18(6):389-400. doi: 10.1038/s41568-018-0003-x. PMID: 29632319
Maris JM
N Engl J Med 2010 Jun 10;362(23):2202-11. doi: 10.1056/NEJMra0804577. PMID: 20558371Free PMC Article

Prognosis

Whittle SB, Smith V, Doherty E, Zhao S, McCarty S, Zage PE
Expert Rev Anticancer Ther 2017 Apr;17(4):369-386. Epub 2017 Mar 15 doi: 10.1080/14737140.2017.1285230. PMID: 28142287
Matthay KK, Maris JM, Schleiermacher G, Nakagawara A, Mackall CL, Diller L, Weiss WA
Nat Rev Dis Primers 2016 Nov 10;2:16078. doi: 10.1038/nrdp.2016.78. PMID: 27830764
Fisher JPH, Tweddle DA
Semin Fetal Neonatal Med 2012 Aug;17(4):207-215. Epub 2012 Jun 4 doi: 10.1016/j.siny.2012.05.002. PMID: 22673527
Maris JM
N Engl J Med 2010 Jun 10;362(23):2202-11. doi: 10.1056/NEJMra0804577. PMID: 20558371Free PMC Article
Nuchtern JG
Semin Pediatr Surg 2006 Feb;15(1):10-6. doi: 10.1053/j.sempedsurg.2005.11.003. PMID: 16458841

Clinical prediction guides

Flaadt T, Ladenstein RL, Ebinger M, Lode HN, Arnardóttir HB, Poetschger U, Schwinger W, Meisel R, Schuster FR, Döring M, Ambros PF, Queudeville M, Fuchs J, Warmann SW, Schäfer J, Seitz C, Schlegel P, Brecht IB, Holzer U, Feuchtinger T, Simon T, Schulte JH, Eggert A, Teltschik HM, Illhardt T, Handgretinger R, Lang P
J Clin Oncol 2023 Jun 10;41(17):3135-3148. Epub 2023 Feb 28 doi: 10.1200/JCO.22.01630. PMID: 36854071Free PMC Article
Nijhuis A, Sikka A, Yogev O, Herendi L, Balcells C, Ma Y, Poon E, Eckold C, Valbuena GN, Xu Y, Liu Y, da Costa BM, Gruet M, Wickremesinghe C, Benito A, Kramer H, Montoya A, Carling D, Want EJ, Jamin Y, Chesler L, Keun HC
Nat Commun 2022 Mar 16;13(1):1380. doi: 10.1038/s41467-022-28907-3. PMID: 35296644Free PMC Article
Zanotti S, Decaesteker B, Vanhauwaert S, De Wilde B, De Vos WH, Speleman F
Br J Cancer 2022 Jun;126(11):1529-1538. Epub 2022 Feb 23 doi: 10.1038/s41416-022-01755-0. PMID: 35197583Free PMC Article
Fisher JPH, Tweddle DA
Semin Fetal Neonatal Med 2012 Aug;17(4):207-215. Epub 2012 Jun 4 doi: 10.1016/j.siny.2012.05.002. PMID: 22673527
Nuchtern JG
Semin Pediatr Surg 2006 Feb;15(1):10-6. doi: 10.1053/j.sempedsurg.2005.11.003. PMID: 16458841

Recent systematic reviews

Kuchalska K, Derwich K, Gotz-Więckowska A
J Pediatr Hematol Oncol 2023 Mar 1;45(2):47-56. Epub 2022 Sep 13 doi: 10.1097/MPH.0000000000002543. PMID: 36161977
Seth N, Seth I, Bulloch G, Siu AHY, Guo A, Chatterjee R, MacManus M, Donnan L
Pediatr Blood Cancer 2022 Mar;69(3):e29415. Epub 2021 Oct 28 doi: 10.1002/pbc.29415. PMID: 34709700
De Bonnecaze G, Lepage B, Rimmer J, Al Hawat A, Vairel B, Serrano E, Chaput B, Vergez S
Eur Arch Otorhinolaryngol 2016 Jan;273(1):21-6. Epub 2014 Oct 17 doi: 10.1007/s00405-014-3320-z. PMID: 25323151
Komotar RJ, Starke RM, Raper DM, Anand VK, Schwartz TH
World Neurosurg 2013 Jul-Aug;80(1-2):148-59. Epub 2012 Dec 7 doi: 10.1016/j.wneu.2012.12.003. PMID: 23228365
Heloury Y, Muthucumaru M, Panabokke G, Cheng W, Kimber C, Leclair MD
J Pediatr Surg 2012 Feb;47(2):415-21. doi: 10.1016/j.jpedsurg.2011.08.003. PMID: 22325405

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