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Breast angiosarcoma

MedGen UID:
272382
•Concept ID:
C1332614
•
Neoplastic Process
Synonym: Angiosarcoma of the breast
 
Monarch Initiative: MONDO:0003024

Definition

A malignant vascular neoplasm arising from the breast. [from NCI]

Professional guidelines

PubMed

The Complex Management of the Breast Angiosarcoma: A Retrospective Study.
Cannella L, Perri F, Clemente O, von Arx C, Pizzolorusso A, Di Bonito M, Bracigliano A, Di Marzo M, Della Vittoria Scarpati G, De Chiara A, Tafuto S
Oncology 2023;101(4):234-239. Epub 2022 Dec 20 doi: 10.1159/000525146. PMID: 36538913
Clinical and Molecular Insights of Radiation-Induced Breast Sarcomas: Is There Hope on the Horizon for Effective Treatment of This Aggressive Disease?
Kokkali S, Moreno JD, Klijanienko J, Theocharis S
Int J Mol Sci 2022 Apr 8;23(8) doi: 10.3390/ijms23084125. PMID: 35456944Free PMC Article
Treatment and Prognosis of Radiation-Associated Breast Angiosarcoma in a Nationwide Population.
Salminen SH, Wiklund T, Sampo MM, Tarkkanen M, Pulliainen L, Böhling TO, Tukiainen E, Hukkinen K, Blomqvist CP
Ann Surg Oncol 2020 Apr;27(4):1002-1010. Epub 2019 Nov 26 doi: 10.1245/s10434-019-08085-1. PMID: 31773514Free PMC Article

Recent clinical studies

Etiology

Breast angiosarcoma after primary breast cancer surgery: A systematic review.
Sato F, Yamamoto T
J Plast Reconstr Aesthet Surg 2022 Sep;75(9):2882-2889. Epub 2022 Jun 21 doi: 10.1016/j.bjps.2022.06.046. PMID: 35907689
Does Angiosarcoma of the Breast Need Nodal Staging?
Herb J, Maduekwe UN, Goel N, Rosenberger LH, Spanheimer PM
J Am Coll Surg 2022 May 1;234(5):774-782. doi: 10.1097/XCS.0000000000000131. PMID: 35426390Free PMC Article
Characteristics and Long-Term Risk of Breast Angiosarcoma.
Friedrich AU, Reisenbichler ES, Heller DR, LeBlanc JM, Park TS, Killelea BK, Lannin DR
Ann Surg Oncol 2021 Sep;28(9):5112-5118. Epub 2021 Feb 18 doi: 10.1245/s10434-021-09689-2. PMID: 33604827
Primary and secondary breast angiosarcoma: single center report and a meta-analysis.
Abdou Y, Elkhanany A, Attwood K, Ji W, Takabe K, Opyrchal M
Breast Cancer Res Treat 2019 Dec;178(3):523-533. Epub 2019 Sep 14 doi: 10.1007/s10549-019-05432-4. PMID: 31522347Free PMC Article
Mammography and MRI manifestations of breast angiosarcoma.
Wu WH, Ji QL, Li ZZ, Wang QN, Liu SY, Yu JF
BMC Womens Health 2019 Jun 10;19(1):73. doi: 10.1186/s12905-019-0769-3. PMID: 31182098Free PMC Article

Diagnosis

Clinical and Molecular Insights of Radiation-Induced Breast Sarcomas: Is There Hope on the Horizon for Effective Treatment of This Aggressive Disease?
Kokkali S, Moreno JD, Klijanienko J, Theocharis S
Int J Mol Sci 2022 Apr 8;23(8) doi: 10.3390/ijms23084125. PMID: 35456944Free PMC Article
Clinicopathologic and immunohistochemical study of breast angiosarcoma.
Yan M, Gilmore H, Bomeisl P, Harbhajanka A
Ann Diagn Pathol 2021 Oct;54:151795. Epub 2021 Jul 19 doi: 10.1016/j.anndiagpath.2021.151795. PMID: 34392127
Characteristics and Long-Term Risk of Breast Angiosarcoma.
Friedrich AU, Reisenbichler ES, Heller DR, LeBlanc JM, Park TS, Killelea BK, Lannin DR
Ann Surg Oncol 2021 Sep;28(9):5112-5118. Epub 2021 Feb 18 doi: 10.1245/s10434-021-09689-2. PMID: 33604827
MYC and NOTCH1-positive postradiation cutaneous angiosarcoma of the breast.
Sheu TG, Hunt KK, Middleton LP
Breast J 2021 Mar;27(3):264-267. Epub 2021 Feb 1 doi: 10.1111/tbj.14171. PMID: 33527629
Angiosarcoma of the breast following surgery and radiotherapy for breast cancer.
Abbott R, Palmieri C
Nat Clin Pract Oncol 2008 Dec;5(12):727-36. Epub 2008 Oct 21 doi: 10.1038/ncponc1242. PMID: 18936792

Therapy

Breast angiosarcoma after primary breast cancer surgery: A systematic review.
Sato F, Yamamoto T
J Plast Reconstr Aesthet Surg 2022 Sep;75(9):2882-2889. Epub 2022 Jun 21 doi: 10.1016/j.bjps.2022.06.046. PMID: 35907689
Treatment and Prognosis of Radiation-Associated Breast Angiosarcoma in a Nationwide Population.
Salminen SH, Wiklund T, Sampo MM, Tarkkanen M, Pulliainen L, Böhling TO, Tukiainen E, Hukkinen K, Blomqvist CP
Ann Surg Oncol 2020 Apr;27(4):1002-1010. Epub 2019 Nov 26 doi: 10.1245/s10434-019-08085-1. PMID: 31773514Free PMC Article
Secondary breast angiosarcoma: A multicentre retrospective survey by the national Italian association of Breast Surgeons (ANISC).
Taffurelli M, Pellegrini A, Meattini I, Orzalesi L, Tinterri C, Roncella M, Terribile D, Caruso F, Tazzioli G, Pollini G, Friedman D, Mariotti C, Cianchetti E, Cabula C, Thomas R, Cedolini C, Rovera F, Grassi M, Lucani G, Cappella A, Bortul M, Stacul G, Scarabeo F, Procaccini E, Galimberti V
Breast 2019 Jun;45:56-60. Epub 2019 Mar 7 doi: 10.1016/j.breast.2019.02.011. PMID: 30877870
Extent of resection and role of adjuvant treatment in resected localized breast angiosarcoma.
McClelland S 3rd, Hatfield J, Degnin C, Chen Y, Mitin T
Breast Cancer Res Treat 2019 Jun;175(2):409-418. Epub 2019 Feb 28 doi: 10.1007/s10549-019-05172-5. PMID: 30820717
Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX Study.
Penel N, Bui BN, Bay JO, Cupissol D, Ray-Coquard I, Piperno-Neumann S, Kerbrat P, Fournier C, Taieb S, Jimenez M, Isambert N, Peyrade F, Chevreau C, Bompas E, Brain EG, Blay JY
J Clin Oncol 2008 Nov 10;26(32):5269-74. Epub 2008 Sep 22 doi: 10.1200/JCO.2008.17.3146. PMID: 18809609

Prognosis

Breast angiosarcoma after primary breast cancer surgery: A systematic review.
Sato F, Yamamoto T
J Plast Reconstr Aesthet Surg 2022 Sep;75(9):2882-2889. Epub 2022 Jun 21 doi: 10.1016/j.bjps.2022.06.046. PMID: 35907689
MYC and NOTCH1-positive postradiation cutaneous angiosarcoma of the breast.
Sheu TG, Hunt KK, Middleton LP
Breast J 2021 Mar;27(3):264-267. Epub 2021 Feb 1 doi: 10.1111/tbj.14171. PMID: 33527629
Primary and secondary breast angiosarcoma: single center report and a meta-analysis.
Abdou Y, Elkhanany A, Attwood K, Ji W, Takabe K, Opyrchal M
Breast Cancer Res Treat 2019 Dec;178(3):523-533. Epub 2019 Sep 14 doi: 10.1007/s10549-019-05432-4. PMID: 31522347Free PMC Article
Breast angiosarcoma that is not related to radiation exposure: a comprehensive review of the literature.
Kaklamanos IG, Birbas K, Syrigos KN, Vlachodimitropoulos D, Goutas N, Bonatsos G
Surg Today 2011 Feb;41(2):163-8. Epub 2011 Jan 26 doi: 10.1007/s00595-010-4341-x. PMID: 21264749
Angiosarcoma of the breast following surgery and radiotherapy for breast cancer.
Abbott R, Palmieri C
Nat Clin Pract Oncol 2008 Dec;5(12):727-36. Epub 2008 Oct 21 doi: 10.1038/ncponc1242. PMID: 18936792

Clinical prediction guides

Angiosarcoma in the breast: a population-based cohort from Sweden.
Olander S, Wennstig AK, Garmo H, Holmberg L, Nilsson G, Blomqvist C, Karlsson F, Wickberg Å, Wärnberg F, Sund M, Wadsten C
Br J Surg 2023 Nov 9;110(12):1850-1856. doi: 10.1093/bjs/znad290. PMID: 37708086
Clinicopathologic and immunohistochemical study of breast angiosarcoma.
Yan M, Gilmore H, Bomeisl P, Harbhajanka A
Ann Diagn Pathol 2021 Oct;54:151795. Epub 2021 Jul 19 doi: 10.1016/j.anndiagpath.2021.151795. PMID: 34392127
Primary and secondary breast angiosarcoma: single center report and a meta-analysis.
Abdou Y, Elkhanany A, Attwood K, Ji W, Takabe K, Opyrchal M
Breast Cancer Res Treat 2019 Dec;178(3):523-533. Epub 2019 Sep 14 doi: 10.1007/s10549-019-05432-4. PMID: 31522347Free PMC Article
Mammography and MRI manifestations of breast angiosarcoma.
Wu WH, Ji QL, Li ZZ, Wang QN, Liu SY, Yu JF
BMC Womens Health 2019 Jun 10;19(1):73. doi: 10.1186/s12905-019-0769-3. PMID: 31182098Free PMC Article
Radiation-Induced Breast Angiosarcoma: Case Report and Clinical Approach.
Peterson CB, Beauregard S
J Cutan Med Surg 2016 Jul;20(4):304-7. Epub 2016 Feb 4 doi: 10.1177/1203475416631525. PMID: 26848144

Recent systematic reviews

Breast angiosarcoma after primary breast cancer surgery: A systematic review.
Sato F, Yamamoto T
J Plast Reconstr Aesthet Surg 2022 Sep;75(9):2882-2889. Epub 2022 Jun 21 doi: 10.1016/j.bjps.2022.06.046. PMID: 35907689
Primary and secondary breast angiosarcoma: single center report and a meta-analysis.
Abdou Y, Elkhanany A, Attwood K, Ji W, Takabe K, Opyrchal M
Breast Cancer Res Treat 2019 Dec;178(3):523-533. Epub 2019 Sep 14 doi: 10.1007/s10549-019-05432-4. PMID: 31522347Free PMC Article

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