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Pediatric infratentorial ependymoblastoma

MedGen UID:
272462
Concept ID:
C1332972
Neoplastic Process
Synonyms: Childhood Infratentorial Embryonal Tumor with Multilayered Rosettes, C19MC-Altered; childhood infratentorial embryonal tumor with Multilayered Rosettes, C19MC-altered; childhood infratentorial embryonal tumour with Multilayered Rosettes, C19MC-altered; Childhood Infratentorial Ependymoblastoma; childhood infratentorial ependymoblastoma; Pediatric Infratentorial Ependymoblastoma; pediatric infratentorial ependymoblastoma
 
Monarch Initiative: MONDO:0004263

Definition

An embryonal tumor with multilayered rosettes, C19MC-altered that arises from the infratentorial region and occurs in children. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPediatric infratentorial ependymoblastoma

Professional guidelines

PubMed

Aziz HF, Bajwa MH, Mushtaq N, Bakhshi SK, Siddiqui K, Khan SA, Shakir M, Masroor M, Suleman F, Enam SA; Pakistan Brain Tumour Consortium
J Pak Med Assoc 2024 Mar;74(3 (Supple-3)):S186-S190. doi: 10.47391/JPMA.S3.GNO-22. PMID: 39262080
Saury JM, Emanuelson I
Pediatr Neurol 2011 Jan;44(1):21-30. doi: 10.1016/j.pediatrneurol.2010.07.004. PMID: 21147383
Slampa P, Pavelka Z, Dusek L, Hynkova L, Sterba J, Ondrova B, Princ D, Novotny T, Kostakova S
Neoplasma 2007;54(1):62-7. PMID: 17203894

Recent clinical studies

Etiology

Suresh H, Morgan BR, Mithani K, Warsi NM, Yan H, Germann J, Boutet A, Loh A, Gouveia FV, Young J, Quon J, Morgado F, Lerch J, Lozano AM, Al-Fatly B, Kühn AA, Laughlin S, Dewan MC, Mabbott D, Gorodetsky C, Bartels U, Huang A, Tabori U, Rutka JT, Drake JM, Kulkarni AV, Dirks P, Taylor MD, Ramaswamy V, Ibrahim GM
Neuro Oncol 2024 May 3;26(5):950-964. doi: 10.1093/neuonc/noad230. PMID: 38079480Free PMC Article
Okonechnikov K, Joshi P, Sepp M, Leiss K, Sarropoulos I, Murat F, Sill M, Beck P, Chan KC, Korshunov A, Sah F, Deng MY, Sturm D, DeSisto J, Donson AM, Foreman NK, Green AL, Robinson G, Orr BA, Gao Q, Darrow E, Hadley JL, Northcott PA, Gojo J, Kawauchi D, Hovestadt V, Filbin MG, von Deimling A, Zuckermann M, Pajtler KW, Kool M, Jones DTW, Jäger N, Kutscher LM, Kaessmann H, Pfister SM
Neuro Oncol 2023 Oct 3;25(10):1895-1909. doi: 10.1093/neuonc/noad124. PMID: 37534924Free PMC Article
Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Raybaud C, Ramaswamy V, Taylor MD, Laughlin S
Childs Nerv Syst 2015 Oct;31(10):1661-76. Epub 2015 Sep 9 doi: 10.1007/s00381-015-2834-z. PMID: 26351220
Pitsika M, Tsitouras V
J Neurosurg Pediatr 2013 Dec;12(6):604-14. Epub 2013 Sep 27 doi: 10.3171/2013.8.PEDS13168. PMID: 24073751

Diagnosis

Suresh H, Morgan BR, Mithani K, Warsi NM, Yan H, Germann J, Boutet A, Loh A, Gouveia FV, Young J, Quon J, Morgado F, Lerch J, Lozano AM, Al-Fatly B, Kühn AA, Laughlin S, Dewan MC, Mabbott D, Gorodetsky C, Bartels U, Huang A, Tabori U, Rutka JT, Drake JM, Kulkarni AV, Dirks P, Taylor MD, Ramaswamy V, Ibrahim GM
Neuro Oncol 2024 May 3;26(5):950-964. doi: 10.1093/neuonc/noad230. PMID: 38079480Free PMC Article
Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Bianchi F, Chieffo DPR, Frassanito P, Di Rocco C, Tamburrini G
Childs Nerv Syst 2020 Jun;36(6):1153-1157. Epub 2019 Jun 14 doi: 10.1007/s00381-019-04252-7. PMID: 31201497
Raybaud C, Ramaswamy V, Taylor MD, Laughlin S
Childs Nerv Syst 2015 Oct;31(10):1661-76. Epub 2015 Sep 9 doi: 10.1007/s00381-015-2834-z. PMID: 26351220
Poretti A, Meoded A, Huisman TA
J Magn Reson Imaging 2012 Jan;35(1):32-47. Epub 2011 Oct 11 doi: 10.1002/jmri.22722. PMID: 21989968

Therapy

Dury RJ, Lourdusamy A, Macarthur DC, Peet AC, Auer DP, Grundy RG, Dineen RA
J Magn Reson Imaging 2022 Jul;56(1):147-157. Epub 2021 Nov 29 doi: 10.1002/jmri.28007. PMID: 34842328
Kasatkin V, Deviaterikova A, Shurupova M, Karelin A
Eur J Phys Rehabil Med 2022 Feb;58(1):51-59. Epub 2021 Jul 12 doi: 10.23736/S1973-9087.21.06854-4. PMID: 34247471Free PMC Article
Devine CA, Liu KX, Ioakeim-Ioannidou M, Susko M, Poussaint TY, Huisman TAGM, Aboian M, Brown D, Zaslowe-Dude C, Rao AD, Orlina LT, Rawal B, Mueller S, Marcus KJ, Terezakis SA, Braunstein SE, Haas-Kogan DA
Int J Radiat Oncol Biol Phys 2019 Dec 1;105(5):1034-1042. Epub 2019 Aug 28 doi: 10.1016/j.ijrobp.2019.08.039. PMID: 31472183
Pitsika M, Tsitouras V
J Neurosurg Pediatr 2013 Dec;12(6):604-14. Epub 2013 Sep 27 doi: 10.3171/2013.8.PEDS13168. PMID: 24073751
Greenberg HS, Chamberlain MC, Glantz MJ, Wang S
Neuro Oncol 2001 Jan;3(1):29-34. doi: 10.1093/neuonc/3.1.29. PMID: 11305414Free PMC Article

Prognosis

Suresh H, Morgan BR, Mithani K, Warsi NM, Yan H, Germann J, Boutet A, Loh A, Gouveia FV, Young J, Quon J, Morgado F, Lerch J, Lozano AM, Al-Fatly B, Kühn AA, Laughlin S, Dewan MC, Mabbott D, Gorodetsky C, Bartels U, Huang A, Tabori U, Rutka JT, Drake JM, Kulkarni AV, Dirks P, Taylor MD, Ramaswamy V, Ibrahim GM
Neuro Oncol 2024 May 3;26(5):950-964. doi: 10.1093/neuonc/noad230. PMID: 38079480Free PMC Article
Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Bianchi F, Chieffo DPR, Frassanito P, Di Rocco C, Tamburrini G
Childs Nerv Syst 2020 Jun;36(6):1153-1157. Epub 2019 Jun 14 doi: 10.1007/s00381-019-04252-7. PMID: 31201497
Raybaud C, Ramaswamy V, Taylor MD, Laughlin S
Childs Nerv Syst 2015 Oct;31(10):1661-76. Epub 2015 Sep 9 doi: 10.1007/s00381-015-2834-z. PMID: 26351220
Greenberg HS, Chamberlain MC, Glantz MJ, Wang S
Neuro Oncol 2001 Jan;3(1):29-34. doi: 10.1093/neuonc/3.1.29. PMID: 11305414Free PMC Article

Clinical prediction guides

Grønbæk JK, Wibroe M, Toescu S, Frič R, Thomsen BL, Møller LN, Grillner P, Gustavsson B, Mallucci C, Aquilina K, Fellows GA, Molinari E, Hjort MA, Westerholm-Ormio M, Kiudeliene R, Mudra K, Hauser P, van Baarsen K, Hoving E, Zipfel J, Nysom K, Schmiegelow K, Sehested A, Juhler M, Mathiasen R; CMS study group
Lancet Child Adolesc Health 2021 Nov;5(11):814-824. Epub 2021 Oct 6 doi: 10.1016/S2352-4642(21)00274-1. PMID: 34624241
Zhang M, Wong SW, Wright JN, Toescu S, Mohammadzadeh M, Han M, Lummus S, Wagner MW, Yecies D, Lai H, Eghbal A, Radmanesh A, Nemelka J, Harward S, Malinzak M, Laughlin S, Perreault S, Braun KRM, Vossough A, Poussaint T, Goetti R, Ertl-Wagner B, Ho CY, Oztekin O, Ramaswamy V, Mankad K, Vitanza NA, Cheshier SH, Said M, Aquilina K, Thompson E, Jaju A, Grant GA, Lober RM, Yeom KW
Neurosurgery 2021 Oct 13;89(5):892-900. doi: 10.1093/neuros/nyab311. PMID: 34392363Free PMC Article
Vinchon M, Leblond P
Neurochirurgie 2021 Feb;67(1):23-27. Epub 2019 Sep 5 doi: 10.1016/j.neuchi.2019.04.006. PMID: 31494131
Reddy N, Ellison DW, Soares BP, Carson KA, Huisman TAGM, Patay Z
J Neuroimaging 2020 Jul;30(4):503-511. Epub 2020 Jun 12 doi: 10.1111/jon.12704. PMID: 32529709
Bianchi F, Chieffo DPR, Frassanito P, Di Rocco C, Tamburrini G
Childs Nerv Syst 2020 Jun;36(6):1153-1157. Epub 2019 Jun 14 doi: 10.1007/s00381-019-04252-7. PMID: 31201497

Recent systematic reviews

Dury RJ, Lourdusamy A, Macarthur DC, Peet AC, Auer DP, Grundy RG, Dineen RA
J Magn Reson Imaging 2022 Jul;56(1):147-157. Epub 2021 Nov 29 doi: 10.1002/jmri.28007. PMID: 34842328

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