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Undifferentiated Neuroblastoma

MedGen UID:
274348
•Concept ID:
C1519787
•
Neoplastic Process

Definition

A neuroblastoma characterized by the absence of differentiating neuroblasts. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUndifferentiated Neuroblastoma

Professional guidelines

PubMed

Polysialylated neural cell adhesion molecule as a marker for differential diagnosis in pediatric tumors.
Glüer S, Schelp C, Gerardy-Schahn R, von Schweinitz D
J Pediatr Surg 1998 Oct;33(10):1516-20. doi: 10.1016/s0022-3468(98)90488-2. PMID: 9802804

Recent clinical studies

Therapy

Five Years Follow-up of Opsoclonus-Myoclonus-Ataxia Syndrome-Associated Neurogenic Tumors in Children.
Aktekin EH, Gezer HÖ, Yazıcı N, Erol İ, Erbay A, Sarıalioğlu F
Neuropediatrics 2024 Feb;55(1):57-62. Epub 2023 Apr 5 doi: 10.1055/s-0043-1768143. PMID: 37019145
Pigment epithelium-derived factor (PEDF) in neuroblastoma: a multifunctional mediator of Schwann cell antitumor activity.
Crawford SE, Stellmach V, Ranalli M, Huang X, Huang L, Volpert O, De Vries GH, Abramson LP, Bouck N
J Cell Sci 2001 Dec;114(Pt 24):4421-8. doi: 10.1242/jcs.114.24.4421. PMID: 11792807
Polysialylated neural cell adhesion molecule in childhood ganglioneuroma and neuroblastoma of different histological grade and clinical stage.
Glüer S, Zense M, Radtke E, von Schweinitz D
Langenbecks Arch Surg 1998 Oct;383(5):340-4. doi: 10.1007/s004230050145. PMID: 9860228
Chemotherapy for neuroendocrine tumors: the Beatson Oncology Centre experience.
Hatton MQ, Reed NS
Clin Oncol (R Coll Radiol) 1997;9(6):385-9. doi: 10.1016/s0936-6555(97)80132-x. PMID: 9448967

Prognosis

Five Years Follow-up of Opsoclonus-Myoclonus-Ataxia Syndrome-Associated Neurogenic Tumors in Children.
Aktekin EH, Gezer HÖ, Yazıcı N, Erol İ, Erbay A, Sarıalioğlu F
Neuropediatrics 2024 Feb;55(1):57-62. Epub 2023 Apr 5 doi: 10.1055/s-0043-1768143. PMID: 37019145
Pediatric neuroblastic tumors: A critical evaluation of cytomorphological features for risk stratification on aspiration cytology.
Behera G, Chhabra G, Mishra P, Sable M
Diagn Cytopathol 2020 May;48(5):464-474. Epub 2020 Feb 11 doi: 10.1002/dc.24389. PMID: 32043835
Polysialylated neural cell adhesion molecule in childhood ganglioneuroma and neuroblastoma of different histological grade and clinical stage.
Glüer S, Zense M, Radtke E, von Schweinitz D
Langenbecks Arch Surg 1998 Oct;383(5):340-4. doi: 10.1007/s004230050145. PMID: 9860228
Chemotherapy for neuroendocrine tumors: the Beatson Oncology Centre experience.
Hatton MQ, Reed NS
Clin Oncol (R Coll Radiol) 1997;9(6):385-9. doi: 10.1016/s0936-6555(97)80132-x. PMID: 9448967
Stage-specific expression of integrin alphaVbeta3 in neuroblastic tumors.
Gladson CL, Hancock S, Arnold MM, Faye-Petersen OM, Castleberry RP, Kelly DR
Am J Pathol 1996 May;148(5):1423-34. PMID: 8623914Free PMC Article

Clinical prediction guides

Investigation of mechanisms underlying the inhibitory effects of metformin against proliferation and growth of neuroblastoma SH-SY5Y cells.
Binlateh T, Reudhabibadh R, Prommeenate P, Hutamekalin P
Toxicol In Vitro 2022 Sep;83:105410. Epub 2022 Jun 5 doi: 10.1016/j.tiv.2022.105410. PMID: 35675846
Pediatric neuroblastic tumors: A critical evaluation of cytomorphological features for risk stratification on aspiration cytology.
Behera G, Chhabra G, Mishra P, Sable M
Diagn Cytopathol 2020 May;48(5):464-474. Epub 2020 Feb 11 doi: 10.1002/dc.24389. PMID: 32043835
Binding, internalization and fate of Huntingtin Exon1 fibrillar assemblies in mitotic and nonmitotic neuroblastoma cells.
Ruiz-Arlandis G, Pieri L, Bousset L, Melki R
Neuropathol Appl Neurobiol 2016 Feb;42(2):137-52. Epub 2015 Jul 20 doi: 10.1111/nan.12258. PMID: 26111612
Induction of apoptosis and differentiation in neuroblastoma and astrocytoma cells by the overexpression of Bin1, a novel Myc interacting protein.
Galderisi U, Di Bernardo G, Cipollaro M, Jori FP, Piegari E, Cascino A, Peluso G, Melone MA
J Cell Biochem 1999 Sep 1;74(3):313-22. PMID: 10412034
Aggressive neuroblastoma simulating Wilms tumor.
Rosenfield NS, Leonidas JC, Barwick KW
Radiology 1988 Jan;166(1 Pt 1):165-7. doi: 10.1148/radiology.166.1.2827230. PMID: 2827230

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