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Intermixed schwannian stroma-rich ganglioneuroblastoma

MedGen UID:
274565
•Concept ID:
C1517444
•
Neoplastic Process
Synonyms: Ganglioneuroblastoma, intermixed; Ganglioneuroblastoma, Intermixed; ganglioneuroblastoma, intermixed; Ganglioneuroblastoma, Intermixed (Schwannian Stroma-Rich); ganglioneuroblastoma, intermixed (Schwannian Stroma-rich); Intermixed ganglioneuroblastoma; intermixed schwannian stroma-rich ganglioneuroblastoma
SNOMED CT: Ganglioneuroblastoma, intermixed (822951003); Intermixed ganglioneuroblastoma (822951003)
 
Monarch Initiative: MONDO:0003326

Definition

A ganglioneuroblastoma characterized by the presence of neuroblastic cells in a Schwannian stroma, without the presence of hemorrhagic neuroblastic nodules. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntermixed schwannian stroma-rich ganglioneuroblastoma

Professional guidelines

PubMed

Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee.
Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B
Cancer 1999 Jul 15;86(2):349-63. PMID: 10421272

Recent clinical studies

Etiology

Genome analysis and gene expression profiling of neuroblastoma and ganglioneuroblastoma reveal differences between neuroblastic and Schwannian stromal cells.
Coco S, Defferrari R, Scaruffi P, Cavazzana A, Di Cristofano C, Longo L, Mazzocco K, Perri P, Gambini C, Moretti S, Bonassi S, Tonini GP
J Pathol 2005 Nov;207(3):346-57. doi: 10.1002/path.1843. PMID: 16178058
The International Neuroblastoma Pathology Classification (the Shimada system).
Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B, Stram DO, Gerbing RB, Lukens JN, Matthay KK, Castleberry RP
Cancer 1999 Jul 15;86(2):364-72. PMID: 10421273
Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee.
Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B
Cancer 1999 Jul 15;86(2):349-63. PMID: 10421272

Diagnosis

The International Neuroblastoma Pathology Classification (the Shimada system).
Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B, Stram DO, Gerbing RB, Lukens JN, Matthay KK, Castleberry RP
Cancer 1999 Jul 15;86(2):364-72. PMID: 10421273

Prognosis

The International Neuroblastoma Pathology Classification (the Shimada system).
Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B, Stram DO, Gerbing RB, Lukens JN, Matthay KK, Castleberry RP
Cancer 1999 Jul 15;86(2):364-72. PMID: 10421273
Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee.
Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B
Cancer 1999 Jul 15;86(2):349-63. PMID: 10421272

Clinical prediction guides

Genome analysis and gene expression profiling of neuroblastoma and ganglioneuroblastoma reveal differences between neuroblastic and Schwannian stromal cells.
Coco S, Defferrari R, Scaruffi P, Cavazzana A, Di Cristofano C, Longo L, Mazzocco K, Perri P, Gambini C, Moretti S, Bonassi S, Tonini GP
J Pathol 2005 Nov;207(3):346-57. doi: 10.1002/path.1843. PMID: 16178058

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