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Uterine corpus dissecting leiomyoma

MedGen UID:
275552
Concept ID:
C1519847
Neoplastic Process
Synonyms: Cotyledonoid Dissecting Leiomyoma; Cotyledonoid dissecting leiomyoma; Sternberg Tumor; Sternberg tumor; Uterine Corpus Dissecting Leiomyoma; uterine corpus dissecting leiomyoma
 
Monarch Initiative: MONDO:0001842

Definition

A rare morphologic variant of uterine corpus leiomyoma. Macroscopically, it is characterized by large, fungating, and multinodular neoplasm masses arising from the uterine corpus, and extending into the broad ligament or the peritoneal cavity. Microscopically, it shows neoplastic smooth muscle cells infiltrating the myometrium. The neoplastic cells are arranged in a micronodular pattern. Hydropic changes and increased vascularity are also present. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUterine corpus dissecting leiomyoma

Recent clinical studies

Etiology

Mairaing K, Huang KG
J Minim Invasive Gynecol 2018 May-Jun;25(4):580-581. Epub 2017 Oct 12 doi: 10.1016/j.jmig.2017.10.009. PMID: 29032253

Diagnosis

Lenz J, Chvátal R, Konečná P
Ceska Gynekol 2020 Winter;85(3):197-200. PMID: 33562973
Ando H, Ogawa M, Watanabe Y, Tsurunaga K, Nakamura C, Tamura H, Ikeda K, Takahashi R, Nakajima R, Yoshida S, Tsujie T, Doi R, Wakimoto A, Adachi S
Int J Gynecol Pathol 2020 May;39(3):227-232. doi: 10.1097/PGP.0000000000000589. PMID: 30789500
Weng SS, Chou YC, Sun FJ
Taiwan J Obstet Gynecol 2018 Feb;57(1):28-31. doi: 10.1016/j.tjog.2017.12.005. PMID: 29458899
Makharoblidze E, Goishvili N, Mchedlishvili M, Khakhutaishvili I, Jangavadze M
Georgian Med News 2013 Mar;(216):7-11. PMID: 23567300
Roth LM, Kirker JA, Insull M, Whittaker J
Int J Gynecol Pathol 2013 Mar;32(2):215-20. doi: 10.1097/PGP.0b013e318257dff4. PMID: 23370645

Therapy

Weng SS, Chou YC, Sun FJ
Taiwan J Obstet Gynecol 2018 Feb;57(1):28-31. doi: 10.1016/j.tjog.2017.12.005. PMID: 29458899

Clinical prediction guides

Lenz J, Chvátal R, Konečná P
Ceska Gynekol 2020 Winter;85(3):197-200. PMID: 33562973
Ando H, Ogawa M, Watanabe Y, Tsurunaga K, Nakamura C, Tamura H, Ikeda K, Takahashi R, Nakajima R, Yoshida S, Tsujie T, Doi R, Wakimoto A, Adachi S
Int J Gynecol Pathol 2020 May;39(3):227-232. doi: 10.1097/PGP.0000000000000589. PMID: 30789500

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