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Atypical Melanocytic Nevus of Genital Type

MedGen UID:
275613
Concept ID:
C1520072
Neoplastic Process
Synonyms: Atypical Melanocytic Nevus of the Genital Type; Atypical Melanocytic Nevus, Genital Type; Atypical Vulvar Nevus

Definition

A small, well circumscribed melanocytic neoplasm that arises from the vulva and affects women in their reproductive years. It is characterized by the presence of junctional nests of melanocytes. Some of the superficial melanocytes show atypia. During pregnancy the atypical melanocytic changes may appear more prominent. This neoplasm is not associated with the presence of dysplastic nevi in other anatomic areas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAtypical Melanocytic Nevus of Genital Type

Recent clinical studies

Etiology

Khalifeh I, Taraif S, Reed JA, Lazar AF, Diwan AH, Prieto VG
Am J Surg Pathol 2007 Jul;31(7):1130-6. doi: 10.1097/PAS.0b013e31802e63a2. PMID: 17592281
Clark WH Jr, Hood AF, Tucker MA, Jampel RM
Hum Pathol 1998 Jan;29(1 Suppl 1):S1-24. doi: 10.1016/s0046-8177(98)80028-2. PMID: 9445124

Diagnosis

Cengiz FP, Emiroglu N, Wellenhof RH
An Bras Dermatol 2015 Mar-Apr;90(2):178-83. doi: 10.1590/abd1806-4841.20153294. PMID: 25830986Free PMC Article
Quddus MR, Rashid LB, Sung CJ, Robinson-Bostom L, Lawrence WD
Dermatol Online J 2010 Feb 15;16(2):9. PMID: 20178705
Ribé A
J Cutan Pathol 2008 Nov;35 Suppl 2:24-7. doi: 10.1111/j.1600-0560.2008.01150.x. PMID: 18976416
Culpepper KS, Granter SR, McKee PH
J Clin Pathol 2004 Nov;57(11):1121-31. doi: 10.1136/jcp.2003.008516. PMID: 15509670Free PMC Article
Clark WH Jr, Hood AF, Tucker MA, Jampel RM
Hum Pathol 1998 Jan;29(1 Suppl 1):S1-24. doi: 10.1016/s0046-8177(98)80028-2. PMID: 9445124

Prognosis

Ribé A
J Cutan Pathol 2008 Nov;35 Suppl 2:24-7. doi: 10.1111/j.1600-0560.2008.01150.x. PMID: 18976416
Lopansri S, Mihm MC Jr
J Cutan Pathol 1979 Jun;6(3):180-94. doi: 10.1111/j.1600-0560.1979.tb01122.x. PMID: 479437

Clinical prediction guides

Cengiz FP, Emiroglu N, Wellenhof RH
An Bras Dermatol 2015 Mar-Apr;90(2):178-83. doi: 10.1590/abd1806-4841.20153294. PMID: 25830986Free PMC Article
Ribé A
J Cutan Pathol 2008 Nov;35 Suppl 2:24-7. doi: 10.1111/j.1600-0560.2008.01150.x. PMID: 18976416

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