U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ovarian adenosarcoma

MedGen UID:
277458
•Concept ID:
C1335169
•
Neoplastic Process
Synonyms: adenosarcoma of ovary; Ovarian Adenosarcoma; ovarian adenosarcoma; Ovarian Mesodermal Adenosarcoma; ovarian mesodermal adenosarcoma; Ovarian Mullerian Adenosarcoma; ovarian Mullerian adenosarcoma; ovarian mullerian adenosarcoma; Ovarian Müllerian Adenosarcoma; ovarian Müllerian adenosarcoma; ovary adenosarcoma
 
Monarch Initiative: MONDO:0002880

Definition

A biphasic neoplasm that arises from the ovary and is characterized by the presence of mullerian-type epithelial tissue in a mesenchymal sarcomatous stroma. The presence of a high grade sarcomatous component is associated with recurrences and metastases. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian adenosarcoma

Professional guidelines

PubMed

Embryonal Rhabdomyosarcoma of the Uterine Cervix: A Clinicopathologic Study of 94 Cases Emphasizing Issues in Differential Diagnosis Staging, and Prognostic Factors.
Devins KM, Young RH, Ghioni M, Burandt E, Bennett JA, Oliva E
Am J Surg Pathol 2022 Nov 1;46(11):1477-1489. Epub 2022 Aug 9 doi: 10.1097/PAS.0000000000001933. PMID: 35941719
DICER1-associated Tumors in the Female Genital Tract: Molecular Basis, Clinicopathologic Features, and Differential Diagnosis.
Han LM, Weiel JJ, Longacre TA, Folkins AK
Adv Anat Pathol 2022 Sep 1;29(5):297-308. Epub 2022 Jul 1 doi: 10.1097/PAP.0000000000000351. PMID: 35778792
Annual report of the Committee on Gynecologic Oncology, the Japan Society of Obstetrics and Gynecology: Annual patient report for 2017 and annual treatment report for 2012.
Nagase S, Ohta T, Takahashi F, Yaegashi N; Board members of the 2020 Committee on Gynecologic Oncology of the Japan Society of Obstetrics and Gynecology
J Obstet Gynaecol Res 2021 May;47(5):1631-1642. Epub 2021 Feb 25 doi: 10.1111/jog.14724. PMID: 33631867

Recent clinical studies

Etiology

Adenosarcoma of the ovary. A case report.
Litta P, Pozzan C, Sacco G, Merlin F, Saccardi C, Ambrosini A
Eur J Gynaecol Oncol 2004;25(4):507-8. PMID: 15285316
Benign and low grade variants of mixed mesodermal tumor (adenosarcoma) of the ovary and adnexal region.
Kao GF, Norris HJ
Cancer 1978 Sep;42(3):1314-24. doi: 10.1002/1097-0142(197809)42:3<1314::aid-cncr2820420342>3.0.co;2-v. PMID: 698918

Diagnosis

Endometriosis Malignant Transformation Review: Rhabdomyosarcoma Arising From an Endometrioma.
Nezhat C, Vu M, Vang N, Ganjoo K, Karam A, Folkins A, Nezhat A, Nezhat F
JSLS 2019 Oct-Dec;23(4) doi: 10.4293/JSLS.2019.00038. PMID: 31624455Free PMC Article
Primary extra-uterine and extra-ovarian mullerian adenosarcoma: case report and literature review.
Mandato VD, Torricelli F, Mastrofilippo V, Valli R, Aguzzoli L, La Sala GB
BMC Cancer 2018 Feb 5;18(1):134. doi: 10.1186/s12885-018-4037-y. PMID: 29402239Free PMC Article
Juvenile granulosa cell tumor arising in ovarian adenosarcoma: an unusual form of sarcomatous overgrowth.
Carleton C, Houghton OP, McCluggage WG
Hum Pathol 2015 Apr;46(4):614-9. Epub 2015 Jan 7 doi: 10.1016/j.humpath.2014.12.010. PMID: 25656930
Ovarian adenosarcoma with extensive deciduoid morphology arising in endometriosis: a case report.
Manipadam MT, Munemane A, Emmanuel P, McCluggage WG
Int J Gynecol Pathol 2008 Jul;27(3):398-401. doi: 10.1097/PGP.0b013e318165e2d0. PMID: 18580317
Müllerian adenosarcoma of the ovary: case report and review of the literature.
Shetty M, Lal N, Vu NH
Ultrasound Q 2007 Sep;23(3):189-91. doi: 10.1097/RUQ.0b013e31814b94f7. PMID: 17805167

Prognosis

Primary extra-uterine and extra-ovarian mullerian adenosarcoma: case report and literature review.
Mandato VD, Torricelli F, Mastrofilippo V, Valli R, Aguzzoli L, La Sala GB
BMC Cancer 2018 Feb 5;18(1):134. doi: 10.1186/s12885-018-4037-y. PMID: 29402239Free PMC Article
Adenosarcoma of the ovary. A case report.
Litta P, Pozzan C, Sacco G, Merlin F, Saccardi C, Ambrosini A
Eur J Gynaecol Oncol 2004;25(4):507-8. PMID: 15285316
Adenosarcoma of the ovary. A light- and electron-microscopic study with review of the literature.
Czernobilsky B, Gillespie JJ, Roth LM
Diagn Gynecol Obstet 1982 Spring;4(1):25-36. PMID: 6280945

Clinical prediction guides

CD10, estrogen and progesterone receptor expression in ovarian adenosarcoma.
Van Mieghem T, Abeler VM, Moerman P, Verbist L, Vergote I, Amant F
Gynecol Oncol 2005 Nov;99(2):493-6. Epub 2005 Jul 26 doi: 10.1016/j.ygyno.2005.06.013. PMID: 16051333

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...