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Testicular Mixed Choriocarcinoma and Teratoma

MedGen UID:
277811
Concept ID:
C1336714
Neoplastic Process
Synonyms: Mixed Choriocarcinoma and Teratoma of Testis; Mixed Choriocarcinoma and Teratoma of the Testis

Definition

A malignant mixed germ cell tumor arising from the testis. It is characterized by the presence of a teratomatous component and malignant syncytiotrophoblastic cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTesticular Mixed Choriocarcinoma and Teratoma

Professional guidelines

PubMed

Rougemont AL, Tille JC
Hum Pathol 2018 Nov;81:26-36. Epub 2018 May 16 doi: 10.1016/j.humpath.2018.04.025. PMID: 29753846
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467
Brandes AA, Pasetto LM, Monfardini S
Cancer Treat Rev 2000 Aug;26(4):233-42. doi: 10.1053/ctrv.2000.0169. PMID: 10913379

Recent clinical studies

Etiology

Wu P, Yang Y, Yu Z, Zhao L, Feng S
J Surg Res 2023 Aug;288:362-371. Epub 2023 Apr 14 doi: 10.1016/j.jss.2023.03.018. PMID: 37062232
Gondim DD, Ulbright TM, Cheng L, Idrees MT
Am J Surg Pathol 2017 Jun;41(6):788-794. doi: 10.1097/PAS.0000000000000830. PMID: 28296679
Al-Hussain T, Bakshi N, Akhtar M
Adv Anat Pathol 2015 May;22(3):202-12. doi: 10.1097/PAP.0000000000000066. PMID: 25844678
Sesterhenn IA, Davis CJ Jr
Cancer Control 2004 Nov-Dec;11(6):374-87. doi: 10.1177/107327480401100605. PMID: 15625525
Ulbright TM
Am J Surg Pathol 1993 Nov;17(11):1075-91. doi: 10.1097/00000478-199311000-00001. PMID: 8214253

Diagnosis

Pęksa R, Kunc M, Bieńkowski M, Popęda M, Biernat W
Pol J Pathol 2022;73(2):159-165. doi: 10.5114/pjp.2022.120098. PMID: 36345953
Gondim DD, Ulbright TM, Cheng L, Idrees MT
Am J Surg Pathol 2017 Jun;41(6):788-794. doi: 10.1097/PAS.0000000000000830. PMID: 28296679
Sesterhenn IA, Davis CJ Jr
Cancer Control 2004 Nov-Dec;11(6):374-87. doi: 10.1177/107327480401100605. PMID: 15625525
Weidner N
Semin Diagn Pathol 1999 Feb;16(1):42-50. PMID: 10355653
Ayala AG, Ro JY
Semin Urol Oncol 1998 May;16(2):72-81. PMID: 9649230

Therapy

Pagliaro LC
J Clin Oncol 2017 Apr 1;35(10):1036-1040. Epub 2016 Dec 19 doi: 10.1200/JCO.2016.70.6523. PMID: 27992270
Tiffany P, Morse MJ, Bosl G, Vaughan ED Jr, Sogani PC, Herr HW, Whitmore WF Jr
Cancer 1986 Mar 1;57(5):978-83. doi: 10.1002/1097-0142(19860301)57:5<978::aid-cncr2820570517>3.0.co;2-9. PMID: 3002596
Lapis P, Kopper L, Bodrogi I, Sugár J, Lapis K, Eckhardt S
Oncology 1985;42(2):112-8. doi: 10.1159/000226012. PMID: 2581199
Foster BJ, Javadpour N, Ozols RF
Int J Cell Cloning 1983 Apr;1(1):2-14. doi: 10.1002/stem.5530010103. PMID: 6201566

Prognosis

Wu P, Yang Y, Yu Z, Zhao L, Feng S
J Surg Res 2023 Aug;288:362-371. Epub 2023 Apr 14 doi: 10.1016/j.jss.2023.03.018. PMID: 37062232
Gondim DD, Ulbright TM, Cheng L, Idrees MT
Am J Surg Pathol 2017 Jun;41(6):788-794. doi: 10.1097/PAS.0000000000000830. PMID: 28296679
Brandes AA, Pasetto LM, Monfardini S
Cancer Treat Rev 2000 Aug;26(4):233-42. doi: 10.1053/ctrv.2000.0169. PMID: 10913379
Weidner N
Semin Diagn Pathol 1999 Feb;16(1):42-50. PMID: 10355653
Ayala AG, Ro JY
Semin Urol Oncol 1998 May;16(2):72-81. PMID: 9649230

Clinical prediction guides

Pęksa R, Kunc M, Bieńkowski M, Popęda M, Biernat W
Pol J Pathol 2022;73(2):159-165. doi: 10.5114/pjp.2022.120098. PMID: 36345953
Zhou Y, Rothrock A, Murugan P, Li F, Bu L
Exp Mol Pathol 2022 Jun;126:104761. Epub 2022 Apr 4 doi: 10.1016/j.yexmp.2022.104761. PMID: 35390309
Xiao GQ, Li F, Unger PD, Katerji H, Yang Q, McMahon L, Burstein DE
Mod Pathol 2016 Jun;29(6):591-8. Epub 2016 Feb 26 doi: 10.1038/modpathol.2016.46. PMID: 26916077
Bahrami A, Ro JY, Ayala AG
Arch Pathol Lab Med 2007 Aug;131(8):1267-80. doi: 10.5858/2007-131-1267-AOOTGC. PMID: 17683189
Ayala AG, Ro JY
Semin Urol Oncol 1998 May;16(2):72-81. PMID: 9649230

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