U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Testicular Mixed Yolk Sac Tumor and Teratoma with Seminoma

MedGen UID:
277815
Concept ID:
C1336722
Neoplastic Process
Synonyms: Mixed Endodermal Sinus Neoplasm and Teratoma with Seminoma of Testis; Mixed Endodermal Sinus Neoplasm and Teratoma with Seminoma of the Testis; Mixed Endodermal Sinus Tumor and Teratoma with Seminoma of Testis; Mixed Endodermal Sinus Tumor and Teratoma with Seminoma of the Testis; Mixed Yolk Sac Neoplasm and Teratoma with Seminoma of Testis; Mixed Yolk Sac Neoplasm and Teratoma with Seminoma of the Testis; Mixed Yolk Sac Tumor and Teratoma with Seminoma of Testis; Mixed Yolk Sac Tumor and Teratoma with Seminoma of the Testis; Testicular Mixed Endodermal Sinus Neoplasm and Teratoma with Seminoma; Testicular Mixed Endodermal Sinus Tumor and Teratoma with Seminoma; Testicular Mixed Yolk Sac Neoplasm and Teratoma with Seminoma

Definition

A malignant germ cell tumor arising from the testis. It is characterized by a mixture of yolk sac, teratomatous, and seminomatous morphologic elements. Patients may present with painless or painful testicular swelling. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTesticular Mixed Yolk Sac Tumor and Teratoma with Seminoma

Professional guidelines

PubMed

Beg A, Kumar R, Sahay A, Janu A, Joshi A, Noronha V, Prabhash K, Karimundackal G, Jiwnani S, Agarwal JP, Pramesh CS
Ann Diagn Pathol 2021 Aug;53:151763. Epub 2021 May 26 doi: 10.1016/j.anndiagpath.2021.151763. PMID: 34111707
Rougemont AL, Tille JC
Hum Pathol 2018 Nov;81:26-36. Epub 2018 May 16 doi: 10.1016/j.humpath.2018.04.025. PMID: 29753846
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467

Recent clinical studies

Etiology

Lee K, Kim YI, Oh JS, Seo SY, Yun JK, Lee GD, Choi S, Kim HR, Kim YH, Kim DK, Park SI, Ryu JS
Sci Rep 2023 Oct 17;13(1):17619. doi: 10.1038/s41598-023-44913-x. PMID: 37848723Free PMC Article
Al-Obaidy KI, Idrees MT
Adv Anat Pathol 2021 Jul 1;28(4):258-275. doi: 10.1097/PAP.0000000000000302. PMID: 33871428
Bilen MA, Hess KR, Campbell MT, Wang J, Broaddus RR, Karam JA, Ward JF, Wood CG, Choi SL, Rao P, Zhang M, Naing A, General R, Cauley DH, Lin SH, Logothetis CJ, Pisters LL, Tu SM
Oncotarget 2016 Dec 27;7(52):86280-86289. doi: 10.18632/oncotarget.13380. PMID: 27861143Free PMC Article
Al-Hussain T, Bakshi N, Akhtar M
Adv Anat Pathol 2015 May;22(3):202-12. doi: 10.1097/PAP.0000000000000066. PMID: 25844678
Yakirevich E, Lefel O, Sova Y, Stein A, Cohen O, Izhak OB, Resnick MB
J Pathol 2002 Jan;196(1):67-75. doi: 10.1002/path.996. PMID: 11748644

Diagnosis

Lee K, Kim YI, Oh JS, Seo SY, Yun JK, Lee GD, Choi S, Kim HR, Kim YH, Kim DK, Park SI, Ryu JS
Sci Rep 2023 Oct 17;13(1):17619. doi: 10.1038/s41598-023-44913-x. PMID: 37848723Free PMC Article
Al-Obaidy KI, Idrees MT
Adv Anat Pathol 2021 Jul 1;28(4):258-275. doi: 10.1097/PAP.0000000000000302. PMID: 33871428
Sanfrancesco JM, Trevino KE, Xu H, Ulbright TM, Idrees MT
Am J Surg Pathol 2018 Mar;42(3):306-311. doi: 10.1097/PAS.0000000000001008. PMID: 29309304
Bilen MA, Hess KR, Campbell MT, Wang J, Broaddus RR, Karam JA, Ward JF, Wood CG, Choi SL, Rao P, Zhang M, Naing A, General R, Cauley DH, Lin SH, Logothetis CJ, Pisters LL, Tu SM
Oncotarget 2016 Dec 27;7(52):86280-86289. doi: 10.18632/oncotarget.13380. PMID: 27861143Free PMC Article
Woodward PJ, Sohaey R, O'Donoghue MJ, Green DE
Radiographics 2002 Jan-Feb;22(1):189-216. doi: 10.1148/radiographics.22.1.g02ja14189. PMID: 11796908

Therapy

Stump JA, Acosta AM, Whaley RD, Cheng L, Fang AM, Rais-Bahrami S, Gordetsky JB
Hum Pathol 2022 Oct;128:48-55. Epub 2022 Jul 9 doi: 10.1016/j.humpath.2022.06.026. PMID: 35817140

Prognosis

Lee K, Kim YI, Oh JS, Seo SY, Yun JK, Lee GD, Choi S, Kim HR, Kim YH, Kim DK, Park SI, Ryu JS
Sci Rep 2023 Oct 17;13(1):17619. doi: 10.1038/s41598-023-44913-x. PMID: 37848723Free PMC Article
Stang A, Trocchi P, Kajüter H, Trabert B, Oosterhuis JW, McGlynn KA
Andrology 2023 Jan;11(1):65-72. Epub 2022 Sep 12 doi: 10.1111/andr.13282. PMID: 36059277
Lobo J, Costa AL, Vilela-Salgueiro B, Rodrigues Â, Guimarães R, Cantante M, Lopes P, Antunes L, Jerónimo C, Henrique R
Hum Pathol 2018 Dec;82:113-124. Epub 2018 Jul 21 doi: 10.1016/j.humpath.2018.07.016. PMID: 30041024
Woodward PJ, Sohaey R, O'Donoghue MJ, Green DE
Radiographics 2002 Jan-Feb;22(1):189-216. doi: 10.1148/radiographics.22.1.g02ja14189. PMID: 11796908
Yakirevich E, Lefel O, Sova Y, Stein A, Cohen O, Izhak OB, Resnick MB
J Pathol 2002 Jan;196(1):67-75. doi: 10.1002/path.996. PMID: 11748644

Clinical prediction guides

Lobo J, Costa AL, Vilela-Salgueiro B, Rodrigues Â, Guimarães R, Cantante M, Lopes P, Antunes L, Jerónimo C, Henrique R
Hum Pathol 2018 Dec;82:113-124. Epub 2018 Jul 21 doi: 10.1016/j.humpath.2018.07.016. PMID: 30041024
Malagón HD, Valdez AM, Moran CA, Suster S
Am J Surg Pathol 2007 Sep;31(9):1356-62. doi: 10.1097/PAS.0b013e318033c7c4. PMID: 17721191
Ota S, Hishinuma M, Yamauchi N, Goto A, Morikawa T, Fujimura T, Kitamura T, Kodama T, Aburatani H, Fukayama M
Virchows Arch 2006 Sep;449(3):308-14. Epub 2006 Aug 4 doi: 10.1007/s00428-006-0238-x. PMID: 16896894
Woodward PJ, Sohaey R, O'Donoghue MJ, Green DE
Radiographics 2002 Jan-Feb;22(1):189-216. doi: 10.1148/radiographics.22.1.g02ja14189. PMID: 11796908
Stock C, Ambros IM, Lion T, Haas OA, Zoubek A, Gadner H, Ambros PF
Genes Chromosomes Cancer 1994 Sep;11(1):40-50. doi: 10.1002/gcc.2870110107. PMID: 7529045

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...