U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

DNA Crosslinking

MedGen UID:
307393
Concept ID:
C1511665
Cell or Molecular Dysfunction
Synonym: DNA Crosslink

Definition

DNA Crosslinking involves the formation of a covalent bond between two bases on DNA. (NCI) [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Li Y, Köpper F, Dobbelstein M
Cancer Lett 2018 Aug 1;428:45-54. Epub 2018 Apr 25 doi: 10.1016/j.canlet.2018.04.030. PMID: 29704518
Sangster-Guity N, Conrad BH, Papadopoulos N, Bunz F
Oncogene 2011 Jun 2;30(22):2526-33. Epub 2011 Jan 24 doi: 10.1038/onc.2010.624. PMID: 21258400Free PMC Article
Marsit CJ, Liu M, Nelson HH, Posner M, Suzuki M, Kelsey KT
Oncogene 2004 Jan 29;23(4):1000-4. doi: 10.1038/sj.onc.1207256. PMID: 14647419

Recent clinical studies

Etiology

Ali AM, Singh TR, Meetei AR
Mutat Res 2009 Jul 31;668(1-2):20-6. Epub 2009 Apr 18 doi: 10.1016/j.mrfmmm.2009.04.002. PMID: 19379763Free PMC Article
Jacquemont C, Taniguchi T
BMC Biochem 2007 Nov 22;8 Suppl 1(Suppl 1):S10. doi: 10.1186/1471-2091-8-S1-S10. PMID: 18047734Free PMC Article
Mathew CG
Oncogene 2006 Sep 25;25(43):5875-84. doi: 10.1038/sj.onc.1209878. PMID: 16998502
Taniguchi T, D'Andrea AD
Blood 2006 Jun 1;107(11):4223-33. Epub 2006 Feb 21 doi: 10.1182/blood-2005-10-4240. PMID: 16493006
D'Andrea AD, Grompe M
Nat Rev Cancer 2003 Jan;3(1):23-34. doi: 10.1038/nrc970. PMID: 12509764

Diagnosis

Sun X, Gao C, Xu X, Li M, Zhao X, Wang Y, Wang Y, Zhang S, Yan Z, Liu X, Wu C
EMBO Rep 2023 Sep 6;24(9):e56230. Epub 2023 Jul 25 doi: 10.15252/embr.202256230. PMID: 37489617Free PMC Article
Attard NR, Karran P
Photochem Photobiol Sci 2012 Jan;11(1):62-8. Epub 2011 Aug 23 doi: 10.1039/c1pp05194f. PMID: 21860872
Auerbach AD
Mutat Res 2009 Jul 31;668(1-2):4-10. Epub 2009 Feb 28 doi: 10.1016/j.mrfmmm.2009.01.013. PMID: 19622403Free PMC Article
Jacquemont C, Taniguchi T
BMC Biochem 2007 Nov 22;8 Suppl 1(Suppl 1):S10. doi: 10.1186/1471-2091-8-S1-S10. PMID: 18047734Free PMC Article
D'Andrea AD, Grompe M
Nat Rev Cancer 2003 Jan;3(1):23-34. doi: 10.1038/nrc970. PMID: 12509764

Therapy

Sun X, Gao C, Xu X, Li M, Zhao X, Wang Y, Wang Y, Zhang S, Yan Z, Liu X, Wu C
EMBO Rep 2023 Sep 6;24(9):e56230. Epub 2023 Jul 25 doi: 10.15252/embr.202256230. PMID: 37489617Free PMC Article
Webster ALH, Sanders MA, Patel K, Dietrich R, Noonan RJ, Lach FP, White RR, Goldfarb A, Hadi K, Edwards MM, Donovan FX, Hoogenboezem RM, Jung M, Sridhar S, Wiley TF, Fedrigo O, Tian H, Rosiene J, Heineman T, Kennedy JA, Bean L, Rosti RO, Tryon R, Gonzalez AM, Rosenberg A, Luo JD, Carroll TS, Shroff S, Beaumont M, Velleuer E, Rastatter JC, Wells SI, Surrallés J, Bagby G, MacMillan ML, Wagner JE, Cancio M, Boulad F, Scognamiglio T, Vaughan R, Beaumont KG, Koren A, Imielinski M, Chandrasekharappa SC, Auerbach AD, Singh B, Kutler DI, Campbell PJ, Smogorzewska A
Nature 2022 Dec;612(7940):495-502. Epub 2022 Nov 30 doi: 10.1038/s41586-022-05253-4. PMID: 36450981Free PMC Article
Dhillon S
Drugs 2021 Jun;81(8):963-969. doi: 10.1007/s40265-021-01522-0. PMID: 33961277
Rycenga HB, Long DT
Curr Opin Pharmacol 2018 Aug;41:20-26. Epub 2018 Apr 18 doi: 10.1016/j.coph.2018.04.004. PMID: 29679802Free PMC Article
Hegi ME, Sciuscio D, Murat A, Levivier M, Stupp R
Clin Cancer Res 2009 Aug 15;15(16):5026-31. Epub 2009 Aug 11 doi: 10.1158/1078-0432.CCR-08-1169. PMID: 19671858

Prognosis

Ma XY, Zhao JF, Ruan Y, Zhang WM, Zhang LQ, Cai ZD, Xu HQ
Molecules 2022 Dec 12;27(24) doi: 10.3390/molecules27248790. PMID: 36557923Free PMC Article
Fan XZ, Chen YF, Zhang SB, He DH, Wei SF, Wang Q, Pan HF, Liu YQ
Phytomedicine 2021 Oct;91:153689. Epub 2021 Aug 6 doi: 10.1016/j.phymed.2021.153689. PMID: 34446320
Essers PBM, van der Heijden M, Verhagen CVM, Ploeg EM, de Roest RH, Leemans CR, Brakenhoff RH, van den Brekel MWM, Bartelink H, Verheij M, Vens C
Cancer Res 2019 Nov 1;79(21):5597-5611. Epub 2019 Sep 12 doi: 10.1158/0008-5472.CAN-18-3388. PMID: 31515237
Taniguchi T, D'Andrea AD
Blood 2006 Jun 1;107(11):4223-33. Epub 2006 Feb 21 doi: 10.1182/blood-2005-10-4240. PMID: 16493006
Begleiter A, Mowat M, Israels LG, Johnston JB
Leuk Lymphoma 1996 Oct;23(3-4):187-201. doi: 10.3109/10428199609054821. PMID: 9031099

Clinical prediction guides

Zhang H, Cheng N, Li Z, Bai L, Fang C, Li Y, Zhang W, Dong X, Jiang M, Liang Y, Zhang S, Mi J, Zhu J, Zhang Y, Chen SJ, Zhao Y, Weng XQ, Hu W, Chen Z, Huang J, Meng G
Cancer Commun (Lond) 2021 Nov;41(11):1116-1136. Epub 2021 Oct 26 doi: 10.1002/cac2.12234. PMID: 34699692Free PMC Article
Jacquemont C, Taniguchi T
BMC Biochem 2007 Nov 22;8 Suppl 1(Suppl 1):S10. doi: 10.1186/1471-2091-8-S1-S10. PMID: 18047734Free PMC Article
Mathew CG
Oncogene 2006 Sep 25;25(43):5875-84. doi: 10.1038/sj.onc.1209878. PMID: 16998502
Taniguchi T, D'Andrea AD
Blood 2006 Jun 1;107(11):4223-33. Epub 2006 Feb 21 doi: 10.1182/blood-2005-10-4240. PMID: 16493006
Begleiter A, Mowat M, Israels LG, Johnston JB
Leuk Lymphoma 1996 Oct;23(3-4):187-201. doi: 10.3109/10428199609054821. PMID: 9031099

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...