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Pulmonary type ovarian small cell carcinoma

MedGen UID:
309517
Concept ID:
C1518737
Neoplastic Process
Synonyms: ovarian small cell carcinoma, pulmonary type; Ovarian Small Cell Carcinoma, Pulmonary-Type; Ovarian Small Cell NEC; Ovarian Small Cell Neuroendocrine Carcinoma; pulmonary type ovarian small cell carcinoma
 
Monarch Initiative: MONDO:0004318

Definition

An aggressive small cell neuroendocrine carcinoma that arises from the ovary. Morphologically, it resembles the small cell carcinoma that arises from the lung. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPulmonary type ovarian small cell carcinoma

Professional guidelines

PubMed

Roskoski R Jr
Pharmacol Res 2017 Jul;121:202-212. Epub 2017 Apr 30 doi: 10.1016/j.phrs.2017.04.022. PMID: 28465216
Labuzek K, Kozłowski M, Szkudłapski D, Sikorska P, Kozłowska M, Okopień B
Eur J Intern Med 2013 Apr;24(3):207-12. Epub 2013 Jan 31 doi: 10.1016/j.ejim.2013.01.009. PMID: 23375875
Cohen JG, Chan JK, Kapp DS
Curr Opin Oncol 2012 Sep;24(5):572-9. doi: 10.1097/CCO.0b013e3283565ed6. PMID: 22820410

Recent clinical studies

Etiology

Bauer TM, Moore KN, Rader JS, Simpkins F, Mita AC, Beck JT, Hart L, Chu Q, Oza A, Tinker AV, Imedio ER, Kumar S, Mugundu G, Jenkins S, Chmielecki J, Jones S, Spigel D, Fu S
Target Oncol 2023 Jul;18(4):517-530. Epub 2023 Jun 6 doi: 10.1007/s11523-023-00965-7. PMID: 37278879Free PMC Article
Kommoss FK, Tessier-Cloutier B, Witkowski L, Forgo E, Koelsche C, Köbel M, Foulkes WD, Lee CH, Kolin DL, von Deimling A, Howitt BE
J Pathol 2022 Jun;257(2):140-145. Epub 2022 Mar 25 doi: 10.1002/path.5889. PMID: 35218556
Hellwig B, Madjar K, Edlund K, Marchan R, Cadenas C, Heimes AS, Almstedt K, Lebrecht A, Sicking I, Battista MJ, Micke P, Schmidt M, Hengstler JG, Rahnenführer J
PLoS One 2016;11(12):e0167585. Epub 2016 Dec 7 doi: 10.1371/journal.pone.0167585. PMID: 27926932Free PMC Article
Labuzek K, Kozłowski M, Szkudłapski D, Sikorska P, Kozłowska M, Okopień B
Eur J Intern Med 2013 Apr;24(3):207-12. Epub 2013 Jan 31 doi: 10.1016/j.ejim.2013.01.009. PMID: 23375875
Dropcho EJ
Ann Neurol 1995 May;37 Suppl 1:S102-13. doi: 10.1002/ana.410370711. PMID: 8968221

Diagnosis

Blatnik A, Dragoš VŠ, Blatnik O, Stegel V, Klančar G, Novaković S, Drev P, Žagar T, Merlo S, Škof E, Bojadžiski MP, Strojnik K, Krajc M
Arch Pathol Lab Med 2024 Mar 1;148(3):299-309. doi: 10.5858/arpa.2022-0297-OA. PMID: 37270804
Bauer TM, Moore KN, Rader JS, Simpkins F, Mita AC, Beck JT, Hart L, Chu Q, Oza A, Tinker AV, Imedio ER, Kumar S, Mugundu G, Jenkins S, Chmielecki J, Jones S, Spigel D, Fu S
Target Oncol 2023 Jul;18(4):517-530. Epub 2023 Jun 6 doi: 10.1007/s11523-023-00965-7. PMID: 37278879Free PMC Article
Kommoss FK, Tessier-Cloutier B, Witkowski L, Forgo E, Koelsche C, Köbel M, Foulkes WD, Lee CH, Kolin DL, von Deimling A, Howitt BE
J Pathol 2022 Jun;257(2):140-145. Epub 2022 Mar 25 doi: 10.1002/path.5889. PMID: 35218556
Shanbhogue KP, Prasad AS, Ucisik-Keser FE, Katabathina VS, Morani AC
Clin Radiol 2021 Apr;76(4):313.e15-313.e26. Epub 2021 Jan 19 doi: 10.1016/j.crad.2020.11.116. PMID: 33353730
Scully RE
Int J Gynecol Pathol 1993 Apr;12(2):148-52. doi: 10.1097/00004347-199304000-00010. PMID: 8385068

Therapy

Bauer TM, Moore KN, Rader JS, Simpkins F, Mita AC, Beck JT, Hart L, Chu Q, Oza A, Tinker AV, Imedio ER, Kumar S, Mugundu G, Jenkins S, Chmielecki J, Jones S, Spigel D, Fu S
Target Oncol 2023 Jul;18(4):517-530. Epub 2023 Jun 6 doi: 10.1007/s11523-023-00965-7. PMID: 37278879Free PMC Article
Liu Z, Lai J, Jiang H, Ma C, Huang H
FASEB J 2021 Jun;35(6):e21603. doi: 10.1096/fj.202100054RR. PMID: 33999448
Labuzek K, Kozłowski M, Szkudłapski D, Sikorska P, Kozłowska M, Okopień B
Eur J Intern Med 2013 Apr;24(3):207-12. Epub 2013 Jan 31 doi: 10.1016/j.ejim.2013.01.009. PMID: 23375875
Mo YY, Moschos SJ
Expert Opin Ther Targets 2005 Dec;9(6):1203-16. doi: 10.1517/14728222.9.6.1203. PMID: 16300471
Dropcho EJ
Ann Neurol 1995 May;37 Suppl 1:S102-13. doi: 10.1002/ana.410370711. PMID: 8968221

Prognosis

Wang J, Ning Y, Du Y, Kang Y
Curr Oncol 2022 Oct 16;29(10):7802-7815. doi: 10.3390/curroncol29100617. PMID: 36290894Free PMC Article
Corgnac S, Boutet M, Kfoury M, Naltet C, Mami-Chouaib F
Front Immunol 2018;9:1904. Epub 2018 Aug 15 doi: 10.3389/fimmu.2018.01904. PMID: 30158938Free PMC Article
Hellwig B, Madjar K, Edlund K, Marchan R, Cadenas C, Heimes AS, Almstedt K, Lebrecht A, Sicking I, Battista MJ, Micke P, Schmidt M, Hengstler JG, Rahnenführer J
PLoS One 2016;11(12):e0167585. Epub 2016 Dec 7 doi: 10.1371/journal.pone.0167585. PMID: 27926932Free PMC Article
Cruz-López O, Conejo-García A, Núñez MC, Kimatrai M, García-Rubiño ME, Morales F, Gómez-Pérez V, Campos JM
Curr Med Chem 2011;18(7):943-63. doi: 10.2174/092986711794940824. PMID: 21254978
Scully RE
Int J Gynecol Pathol 1993 Apr;12(2):148-52. doi: 10.1097/00004347-199304000-00010. PMID: 8385068

Clinical prediction guides

Feng BJ, Li TH, Li YH, Feng JX, Zhang J, Ma JY, Wang YW, Lu SS
BMC Womens Health 2023 Nov 13;23(1):595. doi: 10.1186/s12905-023-02722-4. PMID: 37953251Free PMC Article
Liu Z, Lai J, Jiang H, Ma C, Huang H
FASEB J 2021 Jun;35(6):e21603. doi: 10.1096/fj.202100054RR. PMID: 33999448
Gerber DE, Infante JR, Gordon MS, Goldberg SB, Martín M, Felip E, Martinez Garcia M, Schiller JH, Spigel DR, Cordova J, Westcott V, Wang Y, Shames DS, Choi Y, Kahn R, Dere RC, Samineni D, Xu J, Lin K, Wood K, Royer-Joo S, Lemahieu V, Schuth E, Vaze A, Maslyar D, Humke EW, Burris HA 3rd
Clin Cancer Res 2020 Jan 15;26(2):364-372. Epub 2019 Sep 20 doi: 10.1158/1078-0432.CCR-18-3965. PMID: 31540980
Sun Y, Zhang Y, Lang Z, Huang J, Zou Z
Medicine (Baltimore) 2019 Oct;98(40):e17346. doi: 10.1097/MD.0000000000017346. PMID: 31577729Free PMC Article
Scully RE
Int J Gynecol Pathol 1993 Apr;12(2):148-52. doi: 10.1097/00004347-199304000-00010. PMID: 8385068

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