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Ulcerative Colitis-Associated Dysplasia of the Colorectum

MedGen UID:
313138
•Concept ID:
C1707837
•
Finding
Synonym: Dysplasia in Ulcerative Colitis

Definition

A morphologic finding indicating the presence of dysplastic epithelial changes in a large intestinal tissue sample that is affected by ulcerative colitis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUlcerative Colitis-Associated Dysplasia of the Colorectum

Recent clinical studies

Etiology

A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients With Ulcerative Colitis-Associated Colorectal Cancer.
Toiyama Y, Okugawa Y, Tanaka K, Araki T, Uchida K, Hishida A, Uchino M, Ikeuchi H, Hirota S, Kusunoki M, Boland CR, Goel A
Gastroenterology 2017 Dec;153(6):1634-1646.e8. Epub 2017 Aug 25 doi: 10.1053/j.gastro.2017.08.037. PMID: 28847750Free PMC Article
Two distinct groups of colorectal cancer in inflammatory bowel disease.
Brackmann S, Andersen SN, Aamodt G, Roald B, Langmark F, Clausen OP, Aadland E, Fausa O, Rydning A, Vatn MH
Inflamm Bowel Dis 2009 Jan;15(1):9-16. doi: 10.1002/ibd.20542. PMID: 18618636

Diagnosis

A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients With Ulcerative Colitis-Associated Colorectal Cancer.
Toiyama Y, Okugawa Y, Tanaka K, Araki T, Uchida K, Hishida A, Uchino M, Ikeuchi H, Hirota S, Kusunoki M, Boland CR, Goel A
Gastroenterology 2017 Dec;153(6):1634-1646.e8. Epub 2017 Aug 25 doi: 10.1053/j.gastro.2017.08.037. PMID: 28847750Free PMC Article
Two distinct groups of colorectal cancer in inflammatory bowel disease.
Brackmann S, Andersen SN, Aamodt G, Roald B, Langmark F, Clausen OP, Aadland E, Fausa O, Rydning A, Vatn MH
Inflamm Bowel Dis 2009 Jan;15(1):9-16. doi: 10.1002/ibd.20542. PMID: 18618636

Prognosis

A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients With Ulcerative Colitis-Associated Colorectal Cancer.
Toiyama Y, Okugawa Y, Tanaka K, Araki T, Uchida K, Hishida A, Uchino M, Ikeuchi H, Hirota S, Kusunoki M, Boland CR, Goel A
Gastroenterology 2017 Dec;153(6):1634-1646.e8. Epub 2017 Aug 25 doi: 10.1053/j.gastro.2017.08.037. PMID: 28847750Free PMC Article
Two distinct groups of colorectal cancer in inflammatory bowel disease.
Brackmann S, Andersen SN, Aamodt G, Roald B, Langmark F, Clausen OP, Aadland E, Fausa O, Rydning A, Vatn MH
Inflamm Bowel Dis 2009 Jan;15(1):9-16. doi: 10.1002/ibd.20542. PMID: 18618636

Clinical prediction guides

A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients With Ulcerative Colitis-Associated Colorectal Cancer.
Toiyama Y, Okugawa Y, Tanaka K, Araki T, Uchida K, Hishida A, Uchino M, Ikeuchi H, Hirota S, Kusunoki M, Boland CR, Goel A
Gastroenterology 2017 Dec;153(6):1634-1646.e8. Epub 2017 Aug 25 doi: 10.1053/j.gastro.2017.08.037. PMID: 28847750Free PMC Article
Two distinct groups of colorectal cancer in inflammatory bowel disease.
Brackmann S, Andersen SN, Aamodt G, Roald B, Langmark F, Clausen OP, Aadland E, Fausa O, Rydning A, Vatn MH
Inflamm Bowel Dis 2009 Jan;15(1):9-16. doi: 10.1002/ibd.20542. PMID: 18618636

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