U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Recurrent Anterior Pituitary Gland Neoplasm

MedGen UID:
318114
•Concept ID:
C1709873
•
Neoplastic Process
Synonyms: Recurrent Anterior Pituitary Gland Tumor; Recurrent Anterior Pituitary Neoplasm; Recurrent Anterior Pituitary Tumor; Recurrent Neoplasm of Anterior Pituitary; Recurrent Neoplasm of Anterior Pituitary Gland; Recurrent Neoplasm of the Anterior Pituitary; Recurrent Neoplasm of the Anterior Pituitary Gland; Recurrent Tumor of Anterior Pituitary; Recurrent Tumor of Anterior Pituitary Gland; Recurrent Tumor of the Anterior Pituitary; Recurrent Tumor of the Anterior Pituitary Gland; Relapsed Anterior Pituitary Gland Neoplasm; Relapsed Anterior Pituitary Gland Tumor; Relapsed Anterior Pituitary Neoplasm; Relapsed Anterior Pituitary Tumor; Relapsed Neoplasm of Anterior Pituitary; Relapsed Neoplasm of Anterior Pituitary Gland; Relapsed Neoplasm of the Anterior Pituitary; Relapsed Neoplasm of the Anterior Pituitary Gland; Relapsed Tumor of Anterior Pituitary Gland; Relapsed Tumor of the Anterior Pituitary Gland

Definition

The reemergence of a pituitary gland neoplasm after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Anterior Pituitary Gland Neoplasm

Professional guidelines

PubMed

Treatment outcome of metastasis to the pituitary gland: a case series of 21 patients with pathological diagnosis.
Hong S, Atkinson JL, Erickson D, Kizilbash SH, Little JT, Routman DM, Van Gompel JJ
Neurosurg Focus 2023 Aug;55(2):E13. doi: 10.3171/2023.5.FOCUS23185. PMID: 37527679
Cystic lesions of the sellar-suprasellar region - diagnosis and treatment.
Andrysiak-Mamos E, Sagan K, Sagan L, Sowińska-Przepiera E, Syrenicz A
Endokrynol Pol 2018;69(2):212-228. doi: 10.5603/EP.2018.0023. PMID: 29952427
Megavoltage pituitary irradiation in the management of prolactinomas: long-term follow-up.
Tsagarakis S, Grossman A, Plowman PN, Jones AE, Touzel R, Rees LH, Wass JA, Besser GM
Clin Endocrinol (Oxf) 1991 May;34(5):399-406. doi: 10.1111/j.1365-2265.1991.tb00312.x. PMID: 1647898

Recent clinical studies

Etiology

Refractory Pit1 plurihormonal tumours and thyrotroph adenomas.
Nf L, Ai M
Pituitary 2023 Apr;26(2):182-186. Epub 2023 Apr 29 doi: 10.1007/s11102-023-01312-9. PMID: 37117845Free PMC Article
Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET.
Zhang Q, Yao B, Long X, Chen Z, He M, Wu Y, Qiao N, Ma Z, Ye Z, Zhang Y, Yao S, Wang Y, Cheng H, Chen H, Ye H, Wang Y, Li Y, Chen J, Zhang Z, Guo F, Zhao Y
Cell Rep Med 2023 Feb 21;4(2):100934. Epub 2023 Feb 7 doi: 10.1016/j.xcrm.2023.100934. PMID: 36754052Free PMC Article
Clinical and Pathological Aspects of Silent Pituitary Adenomas.
Drummond J, Roncaroli F, Grossman AB, Korbonits M
J Clin Endocrinol Metab 2019 Jul 1;104(7):2473-2489. doi: 10.1210/jc.2018-00688. PMID: 30020466Free PMC Article
The 2017 World Health Organization classification of tumors of the pituitary gland: a summary.
Lopes MBS
Acta Neuropathol 2017 Oct;134(4):521-535. Epub 2017 Aug 18 doi: 10.1007/s00401-017-1769-8. PMID: 28821944
Ectopic sphenoid sinus pituitary adenoma (ESSPA) with normal anterior pituitary gland: a clinicopathologic and immunophenotypic study of 32 cases with a comprehensive review of the english literature.
Thompson LD, Seethala RR, Müller S
Head Neck Pathol 2012 Mar;6(1):75-100. Epub 2012 Mar 20 doi: 10.1007/s12105-012-0336-9. PMID: 22430769Free PMC Article

Diagnosis

Recent Understanding and Future Directions of Recurrent Corticotroph Tumors.
Hinojosa-Amaya JM, Lam-Chung CE, Cuevas-Ramos D
Front Endocrinol (Lausanne) 2021;12:657382. Epub 2021 Apr 26 doi: 10.3389/fendo.2021.657382. PMID: 33986726Free PMC Article
Clinical and Pathological Aspects of Silent Pituitary Adenomas.
Drummond J, Roncaroli F, Grossman AB, Korbonits M
J Clin Endocrinol Metab 2019 Jul 1;104(7):2473-2489. doi: 10.1210/jc.2018-00688. PMID: 30020466Free PMC Article
Silent somatotroph pituitary adenomas: an update.
Langlois F, Woltjer R, Cetas JS, Fleseriu M
Pituitary 2018 Apr;21(2):194-202. doi: 10.1007/s11102-017-0858-y. PMID: 29305680
The 2017 World Health Organization classification of tumors of the pituitary gland: a summary.
Lopes MBS
Acta Neuropathol 2017 Oct;134(4):521-535. Epub 2017 Aug 18 doi: 10.1007/s00401-017-1769-8. PMID: 28821944
Pituicytoma.
Kowalski RJ, Prayson RA, Mayberg MR
Ann Diagn Pathol 2004 Oct;8(5):290-4. doi: 10.1016/j.anndiagpath.2004.07.006. PMID: 15494936

Therapy

Comparative study of complications after primary and revision transsphenoidal endoscopic surgeries.
do Amaral LC, Reis BL, Ribeiro-Oliveira A Jr, da Silva Santos TM, Giannetti AV
Neurosurg Rev 2021 Jun;44(3):1687-1702. Epub 2020 Aug 11 doi: 10.1007/s10143-020-01360-w. PMID: 32783077
Anterior interhemispheric approach for removing large sellar region tumor.
Feng SY, Zhou T, Sun ZH, Bu B, Jiang JL
Medicine (Baltimore) 2018 Jun;97(24):e10840. doi: 10.1097/MD.0000000000010840. PMID: 29901576Free PMC Article
Update on radiation therapy in patients with Cushing's disease.
Tritos NA, Biller BM
Pituitary 2015 Apr;18(2):263-8. doi: 10.1007/s11102-014-0615-4. PMID: 25359445
Pituitary insufficiency as a side effect after radiosurgery for pituitary adenomas: the role of the hypothalamus.
Feigl GC, Pistracher K, Berghold A, Mokry M
J Neurosurg 2010 Dec;113 Suppl:153-59. PMID: 21222294
Surgical treatment of craniopharyngiomas: endocrinological results.
Honegger J, Buchfelder M, Fahlbusch R
J Neurosurg 1999 Feb;90(2):251-7. doi: 10.3171/jns.1999.90.2.0251. PMID: 9950495

Prognosis

Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET.
Zhang Q, Yao B, Long X, Chen Z, He M, Wu Y, Qiao N, Ma Z, Ye Z, Zhang Y, Yao S, Wang Y, Cheng H, Chen H, Ye H, Wang Y, Li Y, Chen J, Zhang Z, Guo F, Zhao Y
Cell Rep Med 2023 Feb 21;4(2):100934. Epub 2023 Feb 7 doi: 10.1016/j.xcrm.2023.100934. PMID: 36754052Free PMC Article
Biological and Therapeutic Implications of the Tumor Microenvironment in Pituitary Adenomas.
Ilie MD, Vasiljevic A, Bertolino P, Raverot G
Endocr Rev 2023 Mar 4;44(2):297-311. doi: 10.1210/endrev/bnac024. PMID: 36269838
Surgical and radiosurgical treatment strategies for Cushing's disease.
Bunevicius A, Laws ER, Vance ML, Iuliano S, Sheehan J
J Neurooncol 2019 Dec;145(3):403-413. Epub 2019 Nov 1 doi: 10.1007/s11060-019-03325-6. PMID: 31677031
Clinical and Pathological Aspects of Silent Pituitary Adenomas.
Drummond J, Roncaroli F, Grossman AB, Korbonits M
J Clin Endocrinol Metab 2019 Jul 1;104(7):2473-2489. doi: 10.1210/jc.2018-00688. PMID: 30020466Free PMC Article
The 2017 World Health Organization classification of tumors of the pituitary gland: a summary.
Lopes MBS
Acta Neuropathol 2017 Oct;134(4):521-535. Epub 2017 Aug 18 doi: 10.1007/s00401-017-1769-8. PMID: 28821944

Clinical prediction guides

Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET.
Zhang Q, Yao B, Long X, Chen Z, He M, Wu Y, Qiao N, Ma Z, Ye Z, Zhang Y, Yao S, Wang Y, Cheng H, Chen H, Ye H, Wang Y, Li Y, Chen J, Zhang Z, Guo F, Zhao Y
Cell Rep Med 2023 Feb 21;4(2):100934. Epub 2023 Feb 7 doi: 10.1016/j.xcrm.2023.100934. PMID: 36754052Free PMC Article
Functioning gonadotroph adenomas in premenopausal women: clinical and molecular characterization and review of the literature.
Wang L, Liang H, Deng C, Yu Q, Gong F, Feng F, You H, Liang Z, Chen B, Deng K, Ma J, Wang R, Yao Y, Zhu H
Pituitary 2022 Jun;25(3):454-467. Epub 2022 Feb 9 doi: 10.1007/s11102-021-01205-9. PMID: 35138520
Clinical characteristics and outcomes of null-cell versus silent gonadotroph adenomas in a series of 1166 pituitary adenomas from a single institution.
Haddad AF, Young JS, Oh T, Pereira MP, Joshi RS, Pereira KM, Osorio RC, Donohue KC, Peeran Z, Sudhir S, Jain S, Beniwal A, Chopra AS, Sandhu NS, Theodosopoulos PV, Kunwar S, El-Sayed IH, Gurrola J, Blevins LS, Aghi MK
Neurosurg Focus 2020 Jun;48(6):E13. doi: 10.3171/2020.3.FOCUS20114. PMID: 32480370
Surgical Management of Rathke Cleft Cysts.
Ratha V, Patil S, Karmarkar VS, Shah NJ, Deopujari CE
World Neurosurg 2017 Nov;107:276-284. Epub 2017 Aug 5 doi: 10.1016/j.wneu.2017.07.164. PMID: 28826711
Pituicytoma.
Kowalski RJ, Prayson RA, Mayberg MR
Ann Diagn Pathol 2004 Oct;8(5):290-4. doi: 10.1016/j.anndiagpath.2004.07.006. PMID: 15494936

Recent systematic reviews

Post-operative surveillance for somatotroph, lactotroph and non-functional pituitary adenomas after curative resection: a systematic review.
Caulley L, Whelan J, Khoury M, Mavedatnia D, Sahlollbey N, Amrani L, Eid A, Doyle MA, Malcolm J, Alkherayf F, Ramsay T, Moher D, Johnson-Obaseki S, Schramm D, Hunink MGM, Kilty SJ
Pituitary 2023 Feb;26(1):73-93. Epub 2022 Nov 23 doi: 10.1007/s11102-022-01289-x. PMID: 36422846
Gonadotroph Pituitary Adenoma Causing Treatable Infertility and Ovarian Hyperstimulation Syndrome in Female Patients: Neurosurgical, Endocrinologic, Gynecologic, and Reproductive Outcomes.
Hasegawa H, Nesvick CL, Erickson D, Cohen SC, Yolcu YU, Khan Z, Raghunathan A, Nippoldt TB, Atkinson JL, Van Gompel JJ
World Neurosurg 2021 Jun;150:e162-e175. Epub 2021 Mar 5 doi: 10.1016/j.wneu.2021.02.115. PMID: 33684575

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...