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Complete heart block with narrow QRS complexes

MedGen UID:
331099
Concept ID:
C1841661
Pathologic Function
HPO: HP:0005178

Definition

A type of third degree heart block in which the escape rhythm arises at the atrioventricular node, which produces a narrow QRS complex. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVComplete heart block with narrow QRS complexes

Conditions with this feature

Progressive familial heart block type II
MedGen UID:
333884
Concept ID:
C1841658
Disease or Syndrome
Progressive familial heart block type II (PFHB2) is an autosomal dominant disorder, similar to type I progressive familial heart block (PFHB1; see 113900). The pattern of PFHB2, however, tends to develop along the lines of a sinus bradycardia with a left posterior hemiblock, presenting clinically as syncopal episodes, Stokes-Adams seizures, or sudden death when complete heart block supervenes (Brink and Torrington, 1977).

Professional guidelines

PubMed

Murakoshi Y, Hoshino K
BMC Pediatr 2023 Aug 5;23(1):384. doi: 10.1186/s12887-023-04200-0. PMID: 37543571Free PMC Article

Recent clinical studies

Etiology

Murakoshi Y, Hoshino K
BMC Pediatr 2023 Aug 5;23(1):384. doi: 10.1186/s12887-023-04200-0. PMID: 37543571Free PMC Article
Poels TT, Engels EB, Kats S, Veenstra L, van Ommen V, Vernooy K, Maessen JG, Prinzen FW
Medicina (Kaunas) 2021 Jul 7;57(7) doi: 10.3390/medicina57070695. PMID: 34356976Free PMC Article
Chen S, Zhang F, Wei Y, Lu X, Zhou G, Liu S
Ann Noninvasive Electrocardiol 2021 Nov;26(6):e12836. Epub 2021 Feb 25 doi: 10.1111/anec.12836. PMID: 33629476Free PMC Article
Ragupathi L, Johnson D, Greenspon A, Frisch D, Ho RT, Pavri BB
Heart Rhythm 2018 Sep;15(9):1372-1377. Epub 2018 Apr 18 doi: 10.1016/j.hrthm.2018.04.013. PMID: 29678778
Bexton RS, Camm AJ
Eur Heart J 1984 Mar;5 Suppl A:111-4. doi: 10.1093/eurheartj/5.suppl_a.111. PMID: 6373268

Diagnosis

Murakoshi Y, Hoshino K
BMC Pediatr 2023 Aug 5;23(1):384. doi: 10.1186/s12887-023-04200-0. PMID: 37543571Free PMC Article
Mehrabi Nasab E, Athari SS
ESC Heart Fail 2023 Apr;10(2):1418-1421. Epub 2022 Nov 8 doi: 10.1002/ehf2.14227. PMID: 36347818Free PMC Article
Qian Z, Qin C, Zou F, Xue S, Wang Y, Zhang X, Qiu Y, Wu H, Hou X, Zhou W, Zou J
Int J Cardiol 2022 Jun 15;357:81-87. Epub 2022 Mar 23 doi: 10.1016/j.ijcard.2022.03.045. PMID: 35337937
Ragupathi L, Johnson D, Greenspon A, Frisch D, Ho RT, Pavri BB
Heart Rhythm 2018 Sep;15(9):1372-1377. Epub 2018 Apr 18 doi: 10.1016/j.hrthm.2018.04.013. PMID: 29678778
Bexton RS, Camm AJ
Eur Heart J 1984 Mar;5 Suppl A:111-4. doi: 10.1093/eurheartj/5.suppl_a.111. PMID: 6373268

Therapy

Mehrabi Nasab E, Athari SS
ESC Heart Fail 2023 Apr;10(2):1418-1421. Epub 2022 Nov 8 doi: 10.1002/ehf2.14227. PMID: 36347818Free PMC Article
Prochnau D, Kühnemund J, Heyne JP
Herzschrittmacherther Elektrophysiol 2022 Sep;33(3):327-329. Epub 2022 Jun 23 doi: 10.1007/s00399-022-00879-3. PMID: 35737134
Poels TT, Engels EB, Kats S, Veenstra L, van Ommen V, Vernooy K, Maessen JG, Prinzen FW
Medicina (Kaunas) 2021 Jul 7;57(7) doi: 10.3390/medicina57070695. PMID: 34356976Free PMC Article
Silvetti MS, Battipaglia I, Pazzano V, Saputo FA, Ravà L, Ammirati A, Calvieri C, Ciani M, Drago F
Pacing Clin Electrophysiol 2018 Sep;41(9):1204-1211. Epub 2018 Aug 9 doi: 10.1111/pace.13447. PMID: 29989185
Du YY, Yao R, Chen QH, Zhao LS, Li L
Cardiol J 2015;22(3):233-40. Epub 2014 Sep 2 doi: 10.5603/CJ.a2014.0060. PMID: 25179315

Prognosis

Qian Z, Qin C, Zou F, Xue S, Wang Y, Zhang X, Qiu Y, Wu H, Hou X, Zhou W, Zou J
Int J Cardiol 2022 Jun 15;357:81-87. Epub 2022 Mar 23 doi: 10.1016/j.ijcard.2022.03.045. PMID: 35337937
Poels TT, Engels EB, Kats S, Veenstra L, van Ommen V, Vernooy K, Maessen JG, Prinzen FW
Medicina (Kaunas) 2021 Jul 7;57(7) doi: 10.3390/medicina57070695. PMID: 34356976Free PMC Article
Ragupathi L, Johnson D, Greenspon A, Frisch D, Ho RT, Pavri BB
Heart Rhythm 2018 Sep;15(9):1372-1377. Epub 2018 Apr 18 doi: 10.1016/j.hrthm.2018.04.013. PMID: 29678778
Tantchou Tchoumi JC, Foresti S, Lupo P, Cappato R, Butera G
Cardiovasc J Afr 2012 Nov;23(10):538-40. doi: 10.5830/CVJA-2012-059. PMID: 23192257Free PMC Article
Bexton RS, Camm AJ
Eur Heart J 1984 Mar;5 Suppl A:111-4. doi: 10.1093/eurheartj/5.suppl_a.111. PMID: 6373268

Clinical prediction guides

Poels TT, Engels EB, Kats S, Veenstra L, van Ommen V, Vernooy K, Maessen JG, Prinzen FW
Medicina (Kaunas) 2021 Jul 7;57(7) doi: 10.3390/medicina57070695. PMID: 34356976Free PMC Article
Wang RX, Lee HC, Li JP, Hodge DO, Cha YM, Friedman PA, Munger TM, Srivathsan K, Pavri BB, Shen WK
Clin Cardiol 2017 Jan;40(1):18-25. Epub 2016 Oct 17 doi: 10.1002/clc.22600. PMID: 27748530Free PMC Article
Lustgarten DL, Crespo EM, Arkhipova-Jenkins I, Lobel R, Winget J, Koehler J, Liberman E, Sheldon T
Heart Rhythm 2015 Jul;12(7):1548-57. Epub 2015 Mar 28 doi: 10.1016/j.hrthm.2015.03.048. PMID: 25828601
Tantchou Tchoumi JC, Foresti S, Lupo P, Cappato R, Butera G
Cardiovasc J Afr 2012 Nov;23(10):538-40. doi: 10.5830/CVJA-2012-059. PMID: 23192257Free PMC Article
Cao K, Chen M, Zou J, Shan Q, Chen C, Yang B, Zhu L, Xu D, Jin Y, Gonska BD
J Interv Card Electrophysiol 2005 Jul;13(2):151-7. doi: 10.1007/s10840-005-0204-6. PMID: 16133843

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