U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Subcutaneous Nodular Fasciitis

MedGen UID:
354209
•Concept ID:
C1710225
•
Neoplastic Process

Definition

A self-limiting, rapidly growing, non-encapsulated benign neoplasm arising from the subcutaneous tissues. It is characterized by the growth of plump spindle-shaped fibroblasts in a storiform pattern, multinucleated osteoclast-like giant cells, red blood cell extravasation, chronic inflammatory cells, and high mitotic activity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubcutaneous Nodular Fasciitis

Professional guidelines

PubMed

Ultrasound features and differential diagnosis for superficial nodular fasciitis.
Zhuang N, Lyu H, Zhao C, Zhang Y, Dong L, Luo H, Tian Y, Xie L, Wu W, Liu L, Sun D, Xie H
J Clin Ultrasound 2023 Oct;51(8):1370-1375. Epub 2023 Aug 21 doi: 10.1002/jcu.23542. PMID: 37602559

Recent clinical studies

Etiology

Ultrasound features and differential diagnosis for superficial nodular fasciitis.
Zhuang N, Lyu H, Zhao C, Zhang Y, Dong L, Luo H, Tian Y, Xie L, Wu W, Liu L, Sun D, Xie H
J Clin Ultrasound 2023 Oct;51(8):1370-1375. Epub 2023 Aug 21 doi: 10.1002/jcu.23542. PMID: 37602559
MR imaging features and a redefinition of the classification system for nodular fasciitis.
Wu SY, Zhao J, Chen HY, Hu MM, Zheng YY, Min JK, Yu RS
Medicine (Baltimore) 2020 Nov 6;99(45):e22906. doi: 10.1097/MD.0000000000022906. PMID: 33157932Free PMC Article
Nodular fasciitis: characteristic imaging features on sonography and magnetic resonance imaging.
Khuu A, Yablon CM, Jacobson JA, Inyang A, Lucas DR, Biermann JS
J Ultrasound Med 2014 Apr;33(4):565-73. doi: 10.7863/ultra.33.4.565. PMID: 24658936
Nodular fasciitis.
Zuber TJ, Finley JL
South Med J 1994 Aug;87(8):842-4. doi: 10.1097/00007611-199408000-00020. PMID: 8052900
Proliferative fasciitis.
Chung EB, Enzinger FM
Cancer 1975 Oct;36(4):1450-8. doi: 10.1002/1097-0142(197510)36:4<1450::aid-cncr2820360437>3.0.co;2-4. PMID: 1058047

Diagnosis

Ultrasound features and differential diagnosis for superficial nodular fasciitis.
Zhuang N, Lyu H, Zhao C, Zhang Y, Dong L, Luo H, Tian Y, Xie L, Wu W, Liu L, Sun D, Xie H
J Clin Ultrasound 2023 Oct;51(8):1370-1375. Epub 2023 Aug 21 doi: 10.1002/jcu.23542. PMID: 37602559
Pseudomyogenic Hemangioendothelioma.
Ansai SI, Morimoto M, Akaishi S
J Nippon Med Sch 2019;86(2):126-130. doi: 10.1272/jnms.JNMS.2019_86-209. PMID: 31130564
Panniculitis.
Ter Poorten MC, Thiers BH
Dermatol Clin 2002 Jul;20(3):421-33, vi. doi: 10.1016/s0733-8635(02)00008-6. PMID: 12170876
Nodular fasciitis.
Zuber TJ, Finley JL
South Med J 1994 Aug;87(8):842-4. doi: 10.1097/00007611-199408000-00020. PMID: 8052900
Proliferative fasciitis.
Chung EB, Enzinger FM
Cancer 1975 Oct;36(4):1450-8. doi: 10.1002/1097-0142(197510)36:4<1450::aid-cncr2820360437>3.0.co;2-4. PMID: 1058047

Therapy

Small vessel vasculitis and relapsing panniculitis in tumour necrosis factor receptor associated periodic syndrome (TRAPS).
Lamprecht P, Moosig F, Adam-Klages S, Mrowietz U, Csernok E, Kirrstetter M, Ahmadi-Simab K, Schroder JO, Gross WL
Ann Rheum Dis 2004 Nov;63(11):1518-20. doi: 10.1136/ard.2003.016733. PMID: 15479908Free PMC Article
Nodular fasciitis: response to intralesional corticosteroids.
Graham BS, Barrett TL, Goltz RW
J Am Acad Dermatol 1999 Mar;40(3):490-2. doi: 10.1016/s0190-9622(99)70506-2. PMID: 10071327

Prognosis

Intraneural Nodular Fasciitis of the Dorsal Scapular Nerve: Case Report and Review of the Literature.
Domazet I, Njiric N, Jakovcevic A, Bitunjac A, Domazet K, Pašalić I, Mrak G
J Neurol Surg A Cent Eur Neurosurg 2023 Jul;84(4):404-407. Epub 2021 Dec 12 doi: 10.1055/s-0041-1739218. PMID: 34897609
Extradural nodular fasciitis arising in the spinal canal.
Kubota K, Okada S, Maeda T, Matsumoto Y, Sakamoto A, Harimaya K, Saiwai H, Kumamaru H, Oda Y, Iwamoto Y
Spine (Phila Pa 1976) 2012 Jan 15;37(2):E133-7. doi: 10.1097/BRS.0b013e318224568a. PMID: 21629160
Intradermal nodular fasciitis of the face.
Kang SK, Kim HH, Ahn SJ, Choi JH, Sung KJ, Moon KC, Koh JK
J Dermatol 2002 May;29(5):310-4. doi: 10.1111/j.1346-8138.2002.tb00269.x. PMID: 12081164
Nodular fasciitis.
Zuber TJ, Finley JL
South Med J 1994 Aug;87(8):842-4. doi: 10.1097/00007611-199408000-00020. PMID: 8052900
Proliferative fasciitis.
Chung EB, Enzinger FM
Cancer 1975 Oct;36(4):1450-8. doi: 10.1002/1097-0142(197510)36:4<1450::aid-cncr2820360437>3.0.co;2-4. PMID: 1058047

Clinical prediction guides

Laryngeal nodular fasciitis in a 75-year-old man: a rare case report and review of the literature.
Wen Y, Ye S, Liu C, Zhu Y
J Int Med Res 2024 Aug;52(8):3000605241259764. doi: 10.1177/03000605241259764. PMID: 39142703Free PMC Article
Ultrasound features and differential diagnosis for superficial nodular fasciitis.
Zhuang N, Lyu H, Zhao C, Zhang Y, Dong L, Luo H, Tian Y, Xie L, Wu W, Liu L, Sun D, Xie H
J Clin Ultrasound 2023 Oct;51(8):1370-1375. Epub 2023 Aug 21 doi: 10.1002/jcu.23542. PMID: 37602559
Nodular fasciitis on the cheek of a child.
Patel D, Samson TD, Cochran EL, Zaenglein AL
Pediatr Dermatol 2021 Mar;38(2):508-509. Epub 2021 Jan 6 doi: 10.1111/pde.14497. PMID: 33403707
MR imaging features and a redefinition of the classification system for nodular fasciitis.
Wu SY, Zhao J, Chen HY, Hu MM, Zheng YY, Min JK, Yu RS
Medicine (Baltimore) 2020 Nov 6;99(45):e22906. doi: 10.1097/MD.0000000000022906. PMID: 33157932Free PMC Article
Aggressive myxoinflammatory fibroblastic sarcoma with multiple site metastases.
Srivastava P, Husain N, Neyaz A, Gupta V
BMJ Case Rep 2018 Jul 18;2018 doi: 10.1136/bcr-2018-224259. PMID: 30021730Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...