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Reactive Vascular Proliferation

MedGen UID:
354461
•Concept ID:
C1711295
•
Disease or Syndrome

Definition

A non-neoplastic proliferation of vessels in reaction to a process. [from NCI]

Professional guidelines

PubMed

Injectable Anti-Inflammatory Supramolecular Nanofiber Hydrogel to Promote Anti-VEGF Therapy in Age-Related Macular Degeneration Treatment.
Gao H, Chen M, Liu Y, Zhang D, Shen J, Ni N, Tang Z, Ju Y, Dai X, Zhuang A, Wang Z, Chen Q, Fan X, Liu Z, Gu P
Adv Mater 2023 Jan;35(2):e2204994. Epub 2022 Dec 11 doi: 10.1002/adma.202204994. PMID: 36349821
Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review.
Hung SW, Zhang R, Tan Z, Chung JPW, Zhang T, Wang CC
Med Res Rev 2021 Jul;41(4):2489-2564. Epub 2021 May 5 doi: 10.1002/med.21802. PMID: 33948974Free PMC Article
Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases.
Cheong DHJ, Tan DWS, Wong FWS, Tran T
Pharmacol Res 2020 Aug;158:104901. Epub 2020 May 13 doi: 10.1016/j.phrs.2020.104901. PMID: 32405226Free PMC Article

Recent clinical studies

Etiology

Calciphylaxis in uraemic and nonuraemic settings: clinical risk factors and histopathological findings.
Ababneh EI, Hassanein M, Saad AM, Cook EE, Ko JS, Fatica RA, Vachharajani TJ, Fernandez AP, Billings SD
Clin Exp Dermatol 2022 Apr;47(4):700-708. Epub 2021 Dec 16 doi: 10.1111/ced.15009. PMID: 34762763
Papillary Endothelial Hyperplasia (Masson Tumor) of the Hand. Surgical and Pathological Consideration from Seven Cases Using New Vascular Markers.
Patai BB, Peterfy N, Szakacs N, Sapi Z, Hetthessy JR
Pathol Oncol Res 2020 Oct;26(4):2083-2090. Epub 2020 Jul 15 doi: 10.1007/s12253-020-00838-8. PMID: 32671676Free PMC Article
Persistent cutaneous abdominal ulcerations secondary to diffuse dermal angiomatosis: an underestimated sign for severe atherosclerosis: A case report.
García-Colmenero L, Martin-Ezquerra G, Gómez-Martín I, Mellado Joan M, Barranco C, Albero-González R, Villar-García J, Pujol RM
Medicine (Baltimore) 2016 Jul;95(29):e4212. doi: 10.1097/MD.0000000000004212. PMID: 27442644Free PMC Article
Cutaneous reactive angiomatosis associated with cholesterol embolism.
Yang YW, Chen CL, Ho WT, Wang KH
J Cutan Pathol 2010 Jun;37(6):692-6. Epub 2009 Jul 10 doi: 10.1111/j.1600-0560.2009.01326.x. PMID: 19614996
Cutaneous vascular proliferations. Part III. Malignant neoplasms, other cutaneous neoplasms with significant vascular component, and disorders erroneously considered as vascular neoplasms.
Requena L, Sangueza OP
J Am Acad Dermatol 1998 Feb;38(2 Pt 1):143-75; quiz 176-8. doi: 10.1016/s0190-9622(98)70237-3. PMID: 9486670

Diagnosis

Calciphylaxis in uraemic and nonuraemic settings: clinical risk factors and histopathological findings.
Ababneh EI, Hassanein M, Saad AM, Cook EE, Ko JS, Fatica RA, Vachharajani TJ, Fernandez AP, Billings SD
Clin Exp Dermatol 2022 Apr;47(4):700-708. Epub 2021 Dec 16 doi: 10.1111/ced.15009. PMID: 34762763
Papillary Endothelial Hyperplasia (Masson Tumor) of the Hand. Surgical and Pathological Consideration from Seven Cases Using New Vascular Markers.
Patai BB, Peterfy N, Szakacs N, Sapi Z, Hetthessy JR
Pathol Oncol Res 2020 Oct;26(4):2083-2090. Epub 2020 Jul 15 doi: 10.1007/s12253-020-00838-8. PMID: 32671676Free PMC Article
Imaging characteristics of intravascular papillary endothelial hyperplasia.
Craig KA, Escobar E, Inwards CY, Kransdorf MJ
Skeletal Radiol 2016 Nov;45(11):1467-72. Epub 2016 Aug 18 doi: 10.1007/s00256-016-2445-0. PMID: 27538971
Serious renal hemorrhage in Masson tumor.
Rizza V, Coletti G, Di Cocco P, Mazzotta C, Famulari A, Pisani F
Transplant Proc 2009 May;41(4):1402-4. doi: 10.1016/j.transproceed.2009.03.010. PMID: 19460571
Cutaneous reactive angiomatoses: patterns and classification of reactive vascular proliferation.
Rongioletti F, Rebora A
J Am Acad Dermatol 2003 Nov;49(5):887-96. doi: 10.1016/s0190-9622(03)02100-5. PMID: 14576670

Therapy

Pseudo-Kaposi's sarcoma because of suction-socket lower limb prosthesis.
Trindade F, Requena L
J Cutan Pathol 2009 Apr;36(4):482-5. doi: 10.1111/j.1600-0560.2008.01064.x. PMID: 19278437

Prognosis

Papillary Endothelial Hyperplasia (Masson Tumor) of the Hand. Surgical and Pathological Consideration from Seven Cases Using New Vascular Markers.
Patai BB, Peterfy N, Szakacs N, Sapi Z, Hetthessy JR
Pathol Oncol Res 2020 Oct;26(4):2083-2090. Epub 2020 Jul 15 doi: 10.1007/s12253-020-00838-8. PMID: 32671676Free PMC Article
Cutaneous vascular proliferations. Part III. Malignant neoplasms, other cutaneous neoplasms with significant vascular component, and disorders erroneously considered as vascular neoplasms.
Requena L, Sangueza OP
J Am Acad Dermatol 1998 Feb;38(2 Pt 1):143-75; quiz 176-8. doi: 10.1016/s0190-9622(98)70237-3. PMID: 9486670
Spindle cell hemangioendothelioma exhibits the ultrastructural features of reactive vascular proliferation rather than of angiosarcoma.
Imayama S, Murakamai Y, Hashimoto H, Hori Y
Am J Clin Pathol 1992 Feb;97(2):279-87. doi: 10.1093/ajcp/97.2.279. PMID: 1372149
Cutaneous histopathologic findings in 'antiphospholipid syndrome'. Correlation with disease, including human immunodeficiency virus disease.
Smith KJ, Skelton HG 3rd, James WD, Angritt P, Scherbenske J, Vaughan K, Lupton GP
Arch Dermatol 1990 Sep;126(9):1176-83. doi: 10.1001/archderm.126.9.1176. PMID: 2118749
A clinical histologic, and immunologic study of a case of metastatic malignant melanoma undergoing spontaneous remission.
Bodurtha AJ, Berkelhammer J, Kim YH, Laucius JF, Mastrangelo MJ
Cancer 1976 Feb;37(2):735-42. doi: 10.1002/1097-0142(197602)37:2<735::aid-cncr2820370221>3.0.co;2-z. PMID: 943226

Clinical prediction guides

Spindle cell hemangioendothelioma exhibits the ultrastructural features of reactive vascular proliferation rather than of angiosarcoma.
Imayama S, Murakamai Y, Hashimoto H, Hori Y
Am J Clin Pathol 1992 Feb;97(2):279-87. doi: 10.1093/ajcp/97.2.279. PMID: 1372149
Cutaneous histopathologic findings in 'antiphospholipid syndrome'. Correlation with disease, including human immunodeficiency virus disease.
Smith KJ, Skelton HG 3rd, James WD, Angritt P, Scherbenske J, Vaughan K, Lupton GP
Arch Dermatol 1990 Sep;126(9):1176-83. doi: 10.1001/archderm.126.9.1176. PMID: 2118749
Mucinous ovarian tumors with giant cell mural nodules. A report of two cases.
Russell P, Wills EJ, Schweitzer P, Bannatyne PM
Diagn Gynecol Obstet 1981 Fall;3(3):233-49. PMID: 6276116
A clinical histologic, and immunologic study of a case of metastatic malignant melanoma undergoing spontaneous remission.
Bodurtha AJ, Berkelhammer J, Kim YH, Laucius JF, Mastrangelo MJ
Cancer 1976 Feb;37(2):735-42. doi: 10.1002/1097-0142(197602)37:2<735::aid-cncr2820370221>3.0.co;2-z. PMID: 943226

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