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Metatypical basal cell carcinoma

MedGen UID:
362831
•Concept ID:
C1883040
•
Neoplastic Process
Synonym: Skin Metatypical Carcinoma
 
Monarch Initiative: MONDO:0002938

Definition

A skin carcinoma displaying cytological characteristics intermediate to nodular basal cell carcinoma and squamous cell carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetatypical basal cell carcinoma

Professional guidelines

PubMed

Pathophysiology, Histopathology, and Differential Diagnostics of Basal Cell Carcinoma and Cutaneous Squamous Cell Carcinoma-An Update from the Pathologist's Point of View.
Cocuz IG, Popelea MC, Niculescu R, Manea A, Sabău AH, Tinca AC, Szoke AR, Budin CE, Stoian A, Morariu SH, Cotoi TC, Cocuz ME, Cotoi OS
Int J Mol Sci 2024 Feb 13;25(4) doi: 10.3390/ijms25042220. PMID: 38396897Free PMC Article
Reappraising basosquamous carcinoma: a summary of histologic features, diagnosis, and treatment.
Shukla S, Khachemoune A
Arch Dermatol Res 2020 Nov;312(9):605-609. Epub 2020 Mar 12 doi: 10.1007/s00403-020-02058-1. PMID: 32166375
Some further features for differential diagnosis between squamous cell carcinomas and basal cell epitheliomas.
Tosca A, Varelzidis A, Bassioukas K, Hatzis J, Nicolis G, Stratigos J
Dermatologica 1985;171(1):21-6. doi: 10.1159/000249381. PMID: 2411609

Recent clinical studies

Etiology

Metatypical Basal Cell Carcinoma: A 6-Year Retrospective Study.
Chaabane A, Bacha D, Ayachi K, Kilani H, Kanchel F, Douggaz A, Nechi S, Chelbi E
Skinmed 2019;17(1):24-28. Epub 2019 Mar 19 PMID: 30888944
Relapsing advanced metatypical basal cell carcinomas (MTBCC) of the face: surgical modalities.
Tchernev G, Chokoeva AA, Penev PK, Ananiev J, Nowak A, Bayyoud Y, Philipov S, Cardoso JC, Wollina U
Wien Med Wochenschr 2014 Dec;164(23-24):529-35. Epub 2014 Oct 2 doi: 10.1007/s10354-014-0314-9. PMID: 25274011
Basosquamous carcinoma and metatypical basal cell carcinoma: a review of treatment with Mohs micrographic surgery.
Allen KJ, Cappel MA, Killian JM, Brewer JD
Int J Dermatol 2014 Nov;53(11):1395-403. Epub 2014 Jun 25 doi: 10.1111/ijd.12587. PMID: 24961583
Basosquamous carcinoma.
Garcia C, Poletti E, Crowson AN
J Am Acad Dermatol 2009 Jan;60(1):137-43. doi: 10.1016/j.jaad.2008.09.036. PMID: 19103364
Metatypical basal cell carcinoma: a clinical review.
Tarallo M, Cigna E, Frati R, Delfino S, Innocenzi D, Fama U, Corbianco A, Scuderi N
J Exp Clin Cancer Res 2008 Nov 7;27(1):65. doi: 10.1186/1756-9966-27-65. PMID: 18992138Free PMC Article

Diagnosis

Basosquamous Carcinoma: Comprehensive Clinical and Histopathological Aspects, Novel Imaging Tools, and Therapeutic Approaches.
Murgia G, Denaro N, Boggio F, Nazzaro G, Benzecry V, Bortoluzzi P, Passoni E, Garrone O, Marzano A
Cells 2023 Nov 30;12(23) doi: 10.3390/cells12232737. PMID: 38067165Free PMC Article
Metatypical basal cell carcinoma: from the primary tumour to a generalized metastatic process - description of diagnostics and combination therapy of an extremely rare skin cancer.
Madej-Czerwonka B, Korga-Plewko A
Ann Agric Environ Med 2022 Mar 21;29(1):152-156. Epub 2021 Apr 9 doi: 10.26444/aaem/134660. PMID: 35352920
Metatypical Basal Cell Carcinoma: A 6-Year Retrospective Study.
Chaabane A, Bacha D, Ayachi K, Kilani H, Kanchel F, Douggaz A, Nechi S, Chelbi E
Skinmed 2019;17(1):24-28. Epub 2019 Mar 19 PMID: 30888944
Basosquamous carcinoma.
Garcia C, Poletti E, Crowson AN
J Am Acad Dermatol 2009 Jan;60(1):137-43. doi: 10.1016/j.jaad.2008.09.036. PMID: 19103364
Metatypical basal cell carcinoma: a clinical review.
Tarallo M, Cigna E, Frati R, Delfino S, Innocenzi D, Fama U, Corbianco A, Scuderi N
J Exp Clin Cancer Res 2008 Nov 7;27(1):65. doi: 10.1186/1756-9966-27-65. PMID: 18992138Free PMC Article

Therapy

How to spot a basosquamous carcinoma: a study on demographics, clinical-dermatoscopic features and histopathological correlations.
Sgouros D, Apalla Z, Theofili M, Damaskou V, Kokkalis G, Kitsiou E, Lallas A, Kanelleas A, Stratigos A, Nikolaidou C, Bobos M, Panayiotides I, Rigopoulos D, Katoulis A
Eur J Dermatol 2021 Dec 1;31(6):779-784. doi: 10.1684/ejd.2021.4178. PMID: 34933836
Basosquamous Carcinoma: Controversy, Advances, and Future Directions.
Tan CZ, Rieger KE, Sarin KY
Dermatol Surg 2017 Jan;43(1):23-31. doi: 10.1097/DSS.0000000000000815. PMID: 27340741

Prognosis

Basosquamous Carcinoma: Comprehensive Clinical and Histopathological Aspects, Novel Imaging Tools, and Therapeutic Approaches.
Murgia G, Denaro N, Boggio F, Nazzaro G, Benzecry V, Bortoluzzi P, Passoni E, Garrone O, Marzano A
Cells 2023 Nov 30;12(23) doi: 10.3390/cells12232737. PMID: 38067165Free PMC Article
Metatypical basal cell carcinoma: from the primary tumour to a generalized metastatic process - description of diagnostics and combination therapy of an extremely rare skin cancer.
Madej-Czerwonka B, Korga-Plewko A
Ann Agric Environ Med 2022 Mar 21;29(1):152-156. Epub 2021 Apr 9 doi: 10.26444/aaem/134660. PMID: 35352920
The curious case of a forehead metatypical basal cell carcinoma.
Florescu IP, Turcu EG, Carantino AM, Cocoşilă LC, Enache V, Neagu TP, Jecan CR
Rom J Morphol Embryol 2018;59(1):345-352. PMID: 29940648
Basosquamous carcinoma and metatypical basal cell carcinoma: a review of treatment with Mohs micrographic surgery.
Allen KJ, Cappel MA, Killian JM, Brewer JD
Int J Dermatol 2014 Nov;53(11):1395-403. Epub 2014 Jun 25 doi: 10.1111/ijd.12587. PMID: 24961583
Basosquamous carcinoma.
Garcia C, Poletti E, Crowson AN
J Am Acad Dermatol 2009 Jan;60(1):137-43. doi: 10.1016/j.jaad.2008.09.036. PMID: 19103364

Clinical prediction guides

Mohs micrographic surgery in rare cutaneous tumors: a retrospective study at a Brazilian tertiary university hospital.
Buffo TH, Stelini RF, Serrano JYM, Pontes LT, Magalhães RF, de Moraes AM
An Bras Dermatol 2023 Jan-Feb;98(1):36-46. Epub 2022 Nov 8 doi: 10.1016/j.abd.2022.01.009. PMID: 36369200Free PMC Article
How to spot a basosquamous carcinoma: a study on demographics, clinical-dermatoscopic features and histopathological correlations.
Sgouros D, Apalla Z, Theofili M, Damaskou V, Kokkalis G, Kitsiou E, Lallas A, Kanelleas A, Stratigos A, Nikolaidou C, Bobos M, Panayiotides I, Rigopoulos D, Katoulis A
Eur J Dermatol 2021 Dec 1;31(6):779-784. doi: 10.1684/ejd.2021.4178. PMID: 34933836
The Use of a Polyetheretherketone (PEEK) Implant to Reconstruct the Midface Region.
Hussain RN, Clark M, Berry-Brincat A
Ophthalmic Plast Reconstr Surg 2016 Nov/Dec;32(6):e151-e153. doi: 10.1097/IOP.0000000000000345. PMID: 25393902
Basosquamous carcinoma.
Garcia C, Poletti E, Crowson AN
J Am Acad Dermatol 2009 Jan;60(1):137-43. doi: 10.1016/j.jaad.2008.09.036. PMID: 19103364

Recent systematic reviews

Basosquamous Carcinoma: Controversy, Advances, and Future Directions.
Tan CZ, Rieger KE, Sarin KY
Dermatol Surg 2017 Jan;43(1):23-31. doi: 10.1097/DSS.0000000000000815. PMID: 27340741

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