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Diskitis

MedGen UID:
3866
•Concept ID:
C0012624
•
Disease or Syndrome
Synonyms: Discitides; Discitis; Diskitides; Spondylodiscitides; Spondylodiscitis; Spondylodiskitides; Spondylodiskitis
SNOMED CT: Intervertebral discitis (2304001); Inflammatory discitis (2304001); Discitis (2304001)
 
HPO: HP:0025679

Definition

Inflammation of an intervertebral disk or disk space. [from HPO]

Professional guidelines

PubMed

Atypical Mycobacterial Infections of the Spine: Evaluation and Management.
Wessell NM, Krieg B, Damioli L, Kleck CJ
Orthopedics 2024 Mar-Apr;47(2):e61-e66. Epub 2024 Jan 25 doi: 10.3928/01477447-20240122-05. PMID: 38285551
Management of vertebral diskitis and osteomyelitis.
Khan IA, Vaccaro AR, Zlotolow DA
Orthopedics 1999 Aug;22(8):758-65. doi: 10.3928/0147-7447-19990801-07. PMID: 10465488
Epidemiology, etiology, diagnostic evaluation, and treatment of low back pain.
Borenstein DG
Curr Opin Rheumatol 1997 Mar;9(2):144-50. doi: 10.1097/00002281-199703000-00011. PMID: 9135919

Recent clinical studies

Etiology

Image-Guided Biopsy in Acute Diskitis-Osteomyelitis: A Systematic Review and Meta-Analysis.
Chang CY, Pelzl C, Jesse MK, Habibollahi S, Habib U, Gyftopoulos S
AJR Am J Roentgenol 2023 Apr;220(4):499-511. Epub 2022 Oct 12 doi: 10.2214/AJR.22.28423. PMID: 36222488
Whipple's arthritis.
Puéchal X
Joint Bone Spine 2016 Dec;83(6):631-635. Epub 2016 Aug 5 doi: 10.1016/j.jbspin.2016.07.001. PMID: 27502365
Spinal infections.
Tay BK, Deckey J, Hu SS
J Am Acad Orthop Surg 2002 May-Jun;10(3):188-97. doi: 10.5435/00124635-200205000-00005. PMID: 12041940
Management of vertebral diskitis and osteomyelitis.
Khan IA, Vaccaro AR, Zlotolow DA
Orthopedics 1999 Aug;22(8):758-65. doi: 10.3928/0147-7447-19990801-07. PMID: 10465488
Diskitis in children.
Crawford AH, Kucharzyk DW, Ruda R, Smitherman HC Jr
Clin Orthop Relat Res 1991 May;(266):70-9. PMID: 2019071

Diagnosis

Image-Guided Biopsy in Acute Diskitis-Osteomyelitis: A Systematic Review and Meta-Analysis.
Chang CY, Pelzl C, Jesse MK, Habibollahi S, Habib U, Gyftopoulos S
AJR Am J Roentgenol 2023 Apr;220(4):499-511. Epub 2022 Oct 12 doi: 10.2214/AJR.22.28423. PMID: 36222488
Whipple's arthritis.
Puéchal X
Joint Bone Spine 2016 Dec;83(6):631-635. Epub 2016 Aug 5 doi: 10.1016/j.jbspin.2016.07.001. PMID: 27502365
Imaging in Spondylodiskitis.
Prodi E, Grassi R, Iacobellis F, Cianfoni A
Magn Reson Imaging Clin N Am 2016 Aug;24(3):581-600. doi: 10.1016/j.mric.2016.04.005. PMID: 27417402
Pyogenic spinal infections.
Tali ET, Oner AY, Koc AM
Neuroimaging Clin N Am 2015 May;25(2):193-208. doi: 10.1016/j.nic.2015.01.003. PMID: 25952173
Childhood diskitis.
Early SD, Kay RM, Tolo VT
J Am Acad Orthop Surg 2003 Nov-Dec;11(6):413-20. doi: 10.5435/00124635-200311000-00005. PMID: 14686826

Therapy

Image-Guided Biopsy in Acute Diskitis-Osteomyelitis: A Systematic Review and Meta-Analysis.
Chang CY, Pelzl C, Jesse MK, Habibollahi S, Habib U, Gyftopoulos S
AJR Am J Roentgenol 2023 Apr;220(4):499-511. Epub 2022 Oct 12 doi: 10.2214/AJR.22.28423. PMID: 36222488
Whipple's arthritis.
Puéchal X
Joint Bone Spine 2016 Dec;83(6):631-635. Epub 2016 Aug 5 doi: 10.1016/j.jbspin.2016.07.001. PMID: 27502365
Childhood diskitis.
Early SD, Kay RM, Tolo VT
J Am Acad Orthop Surg 2003 Nov-Dec;11(6):413-20. doi: 10.5435/00124635-200311000-00005. PMID: 14686826
Management of vertebral diskitis and osteomyelitis.
Khan IA, Vaccaro AR, Zlotolow DA
Orthopedics 1999 Aug;22(8):758-65. doi: 10.3928/0147-7447-19990801-07. PMID: 10465488
Diskitis in children.
Crawford AH, Kucharzyk DW, Ruda R, Smitherman HC Jr
Clin Orthop Relat Res 1991 May;(266):70-9. PMID: 2019071

Prognosis

Whipple's arthritis.
Puéchal X
Joint Bone Spine 2016 Dec;83(6):631-635. Epub 2016 Aug 5 doi: 10.1016/j.jbspin.2016.07.001. PMID: 27502365
Anterior thoracolumbar spine exposure: critical review and analysis.
Ballard JL, Carlson G, Chen J, White J
Ann Vasc Surg 2014 Feb;28(2):465-9. Epub 2013 Dec 28 doi: 10.1016/j.avsg.2013.06.026. PMID: 24378244
Neurosurgical aspects of central nervous system infections.
Heth JA
Neuroimaging Clin N Am 2012 Nov;22(4):791-9. doi: 10.1016/j.nic.2012.05.005. PMID: 23122267
Childhood diskitis.
Early SD, Kay RM, Tolo VT
J Am Acad Orthop Surg 2003 Nov-Dec;11(6):413-20. doi: 10.5435/00124635-200311000-00005. PMID: 14686826
Diskitis in children.
Crawford AH, Kucharzyk DW, Ruda R, Smitherman HC Jr
Clin Orthop Relat Res 1991 May;(266):70-9. PMID: 2019071

Clinical prediction guides

Health Care Utilization and Associated Economic Burden of Postoperative Surgical Site Infection after Spinal Surgery with Follow-Up of 24 Months.
Dietz N, Sharma M, Adams S, Ugiliweneza B, Wang D, Bjurström MF, Karikari I, Drazin D, Boakye M
J Neurol Surg A Cent Eur Neurosurg 2023 Jan;84(1):21-29. Epub 2021 Apr 12 doi: 10.1055/s-0040-1720984. PMID: 33845504
Sleep quality in adult hospitalized patients with infection: an observational study.
Manian FA, Manian CJ
Am J Med Sci 2015 Jan;349(1):56-60. doi: 10.1097/MAJ.0000000000000355. PMID: 25319438
Evaluation of the acutely limping child.
Leet AI, Skaggs DL
Am Fam Physician 2000 Feb 15;61(4):1011-8. PMID: 10706154
Evaluation of lower back pain with bone scintigraphy and SPECT.
De Maeseneer M, Lenchik L, Everaert H, Marcelis S, Bossuyt A, Osteaux M, Beeckman P
Radiographics 1999 Jul-Aug;19(4):901-12; discussion 912-4. doi: 10.1148/radiographics.19.4.g99jl03901. PMID: 10464798
Bone and joint infections caused by Kingella kingae: six cases and review of the literature.
de Groot R, Glover D, Clausen C, Smith AL, Wilson CB
Rev Infect Dis 1988 Sep-Oct;10(5):998-1004. doi: 10.1093/clinids/10.5.998. PMID: 3055196

Recent systematic reviews

Image-Guided Biopsy in Acute Diskitis-Osteomyelitis: A Systematic Review and Meta-Analysis.
Chang CY, Pelzl C, Jesse MK, Habibollahi S, Habib U, Gyftopoulos S
AJR Am J Roentgenol 2023 Apr;220(4):499-511. Epub 2022 Oct 12 doi: 10.2214/AJR.22.28423. PMID: 36222488
Imaging of low back pain in children and adolescents.
Faingold R, Saigal G, Azouz EM, Morales A, Albuquerque PA
Semin Ultrasound CT MR 2004 Dec;25(6):490-505. doi: 10.1053/j.sult.2004.09.005. PMID: 15663319

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