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Pyogenic granuloma

MedGen UID:
39085
•Concept ID:
C0085653
•
Neoplastic Process
Synonyms: Lobular capillary hemangioma; PG
SNOMED CT: PG - Pyogenic granuloma (39629007); Capillary hemangioma of granulation tissue type (17372009); Lobular capillary hemangioma (17372009); Granuloma pyogenicum (17372009); Pyogenic granuloma (17372009); Granuloma telangiectaticum (17372009); Pyogenic granuloma (200722003)
 
Monarch Initiative: MONDO:0022096

Definition

A friable, benign vascular neoplasm with lobular capillary architecture that presents as a raised red skin growth. [from NCI]

Professional guidelines

PubMed

Evaluation and management of benign tumors of the eye and eyelid.
Brown R, Fard S, Feng P, Kerr PE
Clin Dermatol 2024 Jul-Aug;42(4):343-350. Epub 2024 Jan 26 doi: 10.1016/j.clindermatol.2024.01.005. PMID: 38281689
Management of Bleeding Pyogenic Granulomas in Acute Care Settings.
Gaw CE, Treat JR, Friedlaender EY, Del Pizzo J
J Emerg Med 2022 Sep;63(3):339-347. Epub 2022 Oct 6 doi: 10.1016/j.jemermed.2022.04.031. PMID: 36210284
S2k guideline: Laser therapy of the skin.
Paasch U, Zidane M, Baron JM, Bund T, Cappius HJ, Drosner M, Feise K, Fischer T, Gauglitz G, Gerber PA, Grunewald S, Herberger K, Jung A, Karsai S, Kautz G, Philipp C, Schädel D, Seitz AT, Nast A
J Dtsch Dermatol Ges 2022 Sep;20(9):1248-1267. Epub 2022 Sep 13 doi: 10.1111/ddg.14879. PMID: 36098675

Recent clinical studies

Therapy

Physiology of pregnancy and oral local anesthesia considerations.
Zhou X, Zhong Y, Pan Z, Zhang J, Pan J
PeerJ 2023;11:e15585. Epub 2023 Jun 29 doi: 10.7717/peerj.15585. PMID: 37404472Free PMC Article
Topical beta-blockers in dermatologic therapy.
Filoni A, Ambrogio F, De Marco A, Pacifico A, Bonamonte D
Dermatol Ther 2021 Jul;34(4):e15016. Epub 2021 Jun 21 doi: 10.1111/dth.15016. PMID: 34075667Free PMC Article
Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails.
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Drug-related nail disease.
Piraccini BM, Alessandrini A
Clin Dermatol 2013 Sep-Oct;31(5):618-26. doi: 10.1016/j.clindermatol.2013.06.013. PMID: 24079591
Oral pyogenic granuloma: a review.
Jafarzadeh H, Sanatkhani M, Mohtasham N
J Oral Sci 2006 Dec;48(4):167-75. doi: 10.2334/josnusd.48.167. PMID: 17220613

Prognosis

Pediatric melanoma update.
Mccormack L, Hawryluk EB
G Ital Dermatol Venereol 2018 Oct;153(5):707-715. Epub 2018 Feb 26 doi: 10.23736/S0392-0488.18.05924-2. PMID: 29485257
Nail tumors.
Richert B, Lecerf P, Caucanas M, André J
Clin Dermatol 2013 Sep-Oct;31(5):602-17. doi: 10.1016/j.clindermatol.2013.06.014. PMID: 24079590
Kaposi sarcoma.
Radu O, Pantanowitz L
Arch Pathol Lab Med 2013 Feb;137(2):289-94. doi: 10.5858/arpa.2012-0101-RS. PMID: 23368874
Pyogenic granuloma.
Lin RL, Janniger CK
Cutis 2004 Oct;74(4):229-33. PMID: 15551715
Tumors of the cornea and conjunctiva.
Spraul CW, Grossniklaus HE
Curr Opin Ophthalmol 1996 Aug;7(4):28-34. doi: 10.1097/00055735-199608000-00006. PMID: 10163636

Clinical prediction guides

World Workshop on Oral Medicine VII: Relative frequency of oral mucosal lesions in children, a scoping review.
Hong CHL, Dean DR, Hull K, Hu SJ, Sim YF, Nadeau C, Gonçalves S, Lodi G, Hodgson TA
Oral Dis 2019 Jun;25 Suppl 1:193-203. doi: 10.1111/odi.13112. PMID: 31034120
Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails.
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Systemic alterations and their oral manifestations in pregnant women.
Silva de Araujo Figueiredo C, Gonçalves Carvalho Rosalem C, Costa Cantanhede AL, Abreu Fonseca Thomaz ÉB, Fontoura Nogueira da Cruz MC
J Obstet Gynaecol Res 2017 Jan;43(1):16-22. doi: 10.1111/jog.13150. PMID: 28074549
Drug-related nail disease.
Piraccini BM, Alessandrini A
Clin Dermatol 2013 Sep-Oct;31(5):618-26. doi: 10.1016/j.clindermatol.2013.06.013. PMID: 24079591
Periungual and subungual pyogenic granuloma.
Piraccini BM, Bellavista S, Misciali C, Tosti A, de Berker D, Richert B
Br J Dermatol 2010 Nov;163(5):941-53. doi: 10.1111/j.1365-2133.2010.09906.x. PMID: 20545691

Recent systematic reviews

Acitretin-induced periungual pyogenic granulomas and review.
Thomas M, Shon W, Truong AK
Dermatol Online J 2021 Jul 15;27(7) doi: 10.5070/D327754369. PMID: 34391333
Beta-Blockers for Pyogenic Granuloma: A Systematic Review of Case Reports, Case Series, and Clinical Trials.
Dany M
J Drugs Dermatol 2019 Oct 1;18(10):1006-1010. PMID: 31584779
Therapeutic approaches to pyogenic granuloma: an updated review.
Plachouri KM, Georgiou S
Int J Dermatol 2019 Jun;58(6):642-648. Epub 2018 Oct 21 doi: 10.1111/ijd.14268. PMID: 30345507
Reactive oral lesions associated with dental implants. A systematic review.
Atarbashi-Moghadam F, Atarbashi-Moghadam S, Namdari M, Shahrabi-Farahani S
J Investig Clin Dent 2018 Nov;9(4):e12342. Epub 2018 May 11 doi: 10.1111/jicd.12342. PMID: 29752778
Conjunctival autograft for pterygium.
Clearfield E, Muthappan V, Wang X, Kuo IC
Cochrane Database Syst Rev 2016 Feb 11;2(2):CD011349. doi: 10.1002/14651858.CD011349.pub2. PMID: 26867004Free PMC Article

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