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Oral Cavity Plasmablastic Lymphoma

MedGen UID:
396465
•Concept ID:
C2698832
•
Neoplastic Process
Synonyms: Oral Mucosa Plasmablastic Lymphoma; Plasmablastic Lymphoma of the Oral Cavity; Plasmablastic Lymphoma of the Oral Mucosa

Definition

A plasmablastic lymphoma that arises from the oral mucosa. It is usually associated with HIV infection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOral Cavity Plasmablastic Lymphoma

Professional guidelines

PubMed

Primary extranodal non-Hodgkin's lymphoma of oral cavity--a single centre retrospective study.
Sirsath NT, Lakshmaiah KC, Das U, Lokanatha D, Chennagiri SP, Ramarao C
J Cancer Res Ther 2014 Oct-Dec;10(4):945-50. doi: 10.4103/0973-1482.136024. PMID: 25579534
Minimum diagnostic criteria for plasmablastic lymphoma of oral/sinonasal region encountered in a tertiary cancer hospital of a developing country.
Kane S, Khurana A, Parulkar G, Shet T, Prabhash K, Nair R, Gujral S
J Oral Pathol Med 2009 Jan;38(1):138-44. Epub 2008 Jul 21 doi: 10.1111/j.1600-0714.2008.00673.x. PMID: 18647219
AIDS-related non-Hodgkin's lymphomas: from pathology and molecular pathogenesis to treatment.
Carbone A
Hum Pathol 2002 Apr;33(4):392-404. doi: 10.1053/hupa.2002.124723. PMID: 12055673

Recent clinical studies

Etiology

Hematologic cancers in individuals infected by HIV.
Carbone A, Vaccher E, Gloghini A
Blood 2022 Feb 17;139(7):995-1012. doi: 10.1182/blood.2020005469. PMID: 34469512
Lymphoid neoplasms of the oral cavity with plasmablastic morphology-a case series and review of the literature.
Bhattacharyya S, Bains APS, Sykes DL, Iverson BR, Sibgatullah R, Kuklani RM
Oral Surg Oral Med Oral Pathol Oral Radiol 2019 Dec;128(6):651-659. Epub 2019 Aug 19 doi: 10.1016/j.oooo.2019.08.001. PMID: 31494113
Primary extranodal non-Hodgkin's lymphoma of oral cavity--a single centre retrospective study.
Sirsath NT, Lakshmaiah KC, Das U, Lokanatha D, Chennagiri SP, Ramarao C
J Cancer Res Ther 2014 Oct-Dec;10(4):945-50. doi: 10.4103/0973-1482.136024. PMID: 25579534
HIV-negative plasmablastic lymphoma: not in the mouth.
Castillo JJ, Winer ES, Stachurski D, Perez K, Jabbour M, Milani C, Colvin GA, Butera JN
Clin Lymphoma Myeloma Leuk 2011 Apr;11(2):185-9. Epub 2011 Apr 8 doi: 10.1016/j.clml.2011.03.008. PMID: 21575922
Oral and extraoral plasmablastic lymphoma: similarities and differences in clinicopathologic characteristics.
Hansra D, Montague N, Stefanovic A, Akunyili I, Harzand A, Natkunam Y, de la Ossa M, Byrne GE, Lossos IS
Am J Clin Pathol 2010 Nov;134(5):710-9. doi: 10.1309/AJCPJH6KEUSECQLU. PMID: 20959653

Diagnosis

CD138- Plasmablastic Lymphoma: A Multi-institutional Study and Review of the Literature.
Choudhuri J, Pan Z, Yuan J, Chen M, Wu X, Zheng G, Zhao C, Yuan Y, Agarwal B, Liu J, Ma MY, Wang Y, Shi Y
Arch Pathol Lab Med 2023 Jun 1;147(6):643-654. doi: 10.5858/arpa.2021-0462-OA. PMID: 36161544
Clinical, pathological and molecular features of plasmablastic lymphoma arising in the gastrointestinal tract: A review and reappraisal.
Sanguedolce F, Zanelli M, Zizzo M, Martino G, Rossi C, Parente P, Ascani S
Pathol Res Pract 2020 Jun;216(6):152973. Epub 2020 Apr 25 doi: 10.1016/j.prp.2020.152973. PMID: 32370987
Non-Hodgkin's lymphoma of the oral cavity and maxillofacial region: a pathologist viewpoint.
Abdelwahed Hussein MR
Expert Rev Hematol 2018 Sep;11(9):737-748. Epub 2018 Aug 21 doi: 10.1080/17474086.2018.1506326. PMID: 30058399
HIV-negative plasmablastic lymphoma: not in the mouth.
Castillo JJ, Winer ES, Stachurski D, Perez K, Jabbour M, Milani C, Colvin GA, Butera JN
Clin Lymphoma Myeloma Leuk 2011 Apr;11(2):185-9. Epub 2011 Apr 8 doi: 10.1016/j.clml.2011.03.008. PMID: 21575922
Plasmablastic lymphoma: a systematic review.
Castillo JJ, Reagan JL
ScientificWorldJournal 2011 Mar 22;11:687-96. doi: 10.1100/tsw.2011.59. PMID: 21442146Free PMC Article

Therapy

Oral plasmablastic lymphoma: A case report.
Zizzo M, Zanelli M, Martiniani R, Sanguedolce F, De Marco L, Martino G, Parente P, Annessi V, Manzini L, Ascani S
Medicine (Baltimore) 2020 Sep 25;99(39):e22335. doi: 10.1097/MD.0000000000022335. PMID: 32991445Free PMC Article
Case of plasmablastic lymphoma of the sigmoid colon and literature review.
Haramura T, Haraguchi M, Irie J, Ito S, Tokai H, Noda K, Kitajima M, Minami S, Inoue K, Sasaki Y, Oshima K, Eguchi S
World J Gastroenterol 2015 Jun 28;21(24):7598-603. doi: 10.3748/wjg.v21.i24.7598. PMID: 26140010Free PMC Article
Plasmablastic lymphoma of the oral cavity in a human immunodeficiency virus-negative patient: a case report with literature review.
Choi SY, Cho YA, Hong SD, Lee JI, Hong SP, Yoon HJ
Oral Surg Oral Med Oral Pathol Oral Radiol 2014 Feb;117(2):e115-20. Epub 2013 Jun 21 doi: 10.1016/j.oooo.2013.04.017. PMID: 23791544
HIV-negative plasmablastic lymphoma: not in the mouth.
Castillo JJ, Winer ES, Stachurski D, Perez K, Jabbour M, Milani C, Colvin GA, Butera JN
Clin Lymphoma Myeloma Leuk 2011 Apr;11(2):185-9. Epub 2011 Apr 8 doi: 10.1016/j.clml.2011.03.008. PMID: 21575922
HIV-associated lymphomas and gamma-herpesviruses.
Carbone A, Cesarman E, Spina M, Gloghini A, Schulz TF
Blood 2009 Feb 5;113(6):1213-24. Epub 2008 Oct 27 doi: 10.1182/blood-2008-09-180315. PMID: 18955561

Prognosis

Clinical, pathological and molecular features of plasmablastic lymphoma arising in the gastrointestinal tract: A review and reappraisal.
Sanguedolce F, Zanelli M, Zizzo M, Martino G, Rossi C, Parente P, Ascani S
Pathol Res Pract 2020 Jun;216(6):152973. Epub 2020 Apr 25 doi: 10.1016/j.prp.2020.152973. PMID: 32370987
Non-Hodgkin's lymphoma of the oral cavity and maxillofacial region: a pathologist viewpoint.
Abdelwahed Hussein MR
Expert Rev Hematol 2018 Sep;11(9):737-748. Epub 2018 Aug 21 doi: 10.1080/17474086.2018.1506326. PMID: 30058399
Plasmablastic lymphoma: a systematic review.
Castillo JJ, Reagan JL
ScientificWorldJournal 2011 Mar 22;11:687-96. doi: 10.1100/tsw.2011.59. PMID: 21442146Free PMC Article
Plasmablastic lymphoma of the oral cavity: a review.
Sarode SC, Sarode GS, Patil A
Oral Oncol 2010 Mar;46(3):146-53. Epub 2010 Feb 6 doi: 10.1016/j.oraloncology.2009.12.009. PMID: 20138565
HIV-associated lymphomas and gamma-herpesviruses.
Carbone A, Cesarman E, Spina M, Gloghini A, Schulz TF
Blood 2009 Feb 5;113(6):1213-24. Epub 2008 Oct 27 doi: 10.1182/blood-2008-09-180315. PMID: 18955561

Clinical prediction guides

Oral plasmablastic lymphoma: A clinicopathological study of 113 cases.
Fonseca FP, Robinson L, van Heerden MB, van Heerden WFP
J Oral Pathol Med 2021 Jul;50(6):594-602. Epub 2021 Jul 1 doi: 10.1111/jop.13210. PMID: 34091967
Clinicopathological analysis of oral plasmablastic lymphoma: A systematic review.
Rodrigues-Fernandes CI, de Souza LL, Santos-Costa SFD, Silva AMB, Pontes HAR, Lopes MA, de Almeida OP, Brennan PA, Fonseca FP
J Oral Pathol Med 2018 Nov;47(10):915-922. Epub 2018 Jul 5 doi: 10.1111/jop.12753. PMID: 29917262
Case of plasmablastic lymphoma of the sigmoid colon and literature review.
Haramura T, Haraguchi M, Irie J, Ito S, Tokai H, Noda K, Kitajima M, Minami S, Inoue K, Sasaki Y, Oshima K, Eguchi S
World J Gastroenterol 2015 Jun 28;21(24):7598-603. doi: 10.3748/wjg.v21.i24.7598. PMID: 26140010Free PMC Article
HIV-negative plasmablastic lymphoma: not in the mouth.
Castillo JJ, Winer ES, Stachurski D, Perez K, Jabbour M, Milani C, Colvin GA, Butera JN
Clin Lymphoma Myeloma Leuk 2011 Apr;11(2):185-9. Epub 2011 Apr 8 doi: 10.1016/j.clml.2011.03.008. PMID: 21575922
Diffuse large B-cell lymphomas with plasmablastic differentiation.
Teruya-Feldstein J
Curr Oncol Rep 2005 Sep;7(5):357-63. doi: 10.1007/s11912-005-0062-5. PMID: 16091196

Recent systematic reviews

Clinicopathological analysis of oral plasmablastic lymphoma: A systematic review.
Rodrigues-Fernandes CI, de Souza LL, Santos-Costa SFD, Silva AMB, Pontes HAR, Lopes MA, de Almeida OP, Brennan PA, Fonseca FP
J Oral Pathol Med 2018 Nov;47(10):915-922. Epub 2018 Jul 5 doi: 10.1111/jop.12753. PMID: 29917262
Plasmablastic lymphoma: a systematic review.
Castillo JJ, Reagan JL
ScientificWorldJournal 2011 Mar 22;11:687-96. doi: 10.1100/tsw.2011.59. PMID: 21442146Free PMC Article

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